Oral Antibiotic
Reviews
3.2
1954 Reviews
Oral Antibiotic
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Should never be used on its own and for a maximum of 3 months.
Oral Antibiotic
Side Effects
High
Oral Antibiotic
Acne.org’s Real World Take
Antibiotics should be used for a maximum of 3 months, provide only moderate benefit and only to some people, and may lead to side effects and strains of resistant bacteria. Studies do show they can reduce severe acne in the short term, but approach with caution and stay your own advocate.
Oral Antibiotic
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Minocycline
Compare To Other Treatments
5
17.3%
4
27.7%
3
24%
2
16%
1
14.9%

Used Minocycline? Rate It:

Choose from 1 to 5 stars
February 15, 2011

Pros:

Acne... what acne? I used minocycline for approximately 6 months. I went to the dermo in June for the first time... I was cleared by the end of August (in time for my wedding and strapless dress!) Still had some pigmentation issues (serious bacne), but no active acne on either my face or back. At this point I was taking 1 pill every other day.

Cons:

I luckily handled the side effects well. If you take Minocycline, do so with FOOD, and a serving of yogurt once a day. Like so many antibiotics... stomach issues. I also noticed increased staining of my teeth. Which is one reason why I stopped taking it, and am trying out the regimen. So far, so good.

Great in the short term to give you a boost and clear up your acne. Takes longer to absorb into the back, so it took a little longer for the bacne to clear up in comparison to my face. Side effects can be quite problematic (see comment about teeth, and digestive issues in cons). Again, I suggest short term use, and fade off to a topical regimen.
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February 2, 2011

Pros:

Clearned acne somewhat.

Cons:

Terrible side effects- migraines, loss of appatite, dizziness, blurred vision PSEUDO TUMOR.

I was on this antibiotic for about 3-4 months. it worked minimally, no significant improvement. In december i started getting migraines daily at the exact same time. Over christmas break that got so bad i couldn't move from laying down or pass out. I was taken to the ER give a thousand of tests. i had my eyes checked because it was getting very hard to see. I had a pseudo tumor resulting from the minocycline, which is an increase of spinal fluid that gives sever headaches and causes vision impairments. i had to stop it immediately and can never take it again. overall, not worth it even a little bit. the pain i went through as a result was like being tortured. a week straight on the couch because i had a spinal tap to remove the fluid, and the pain only got worse. now, about 2 months later im almost back to normal and acne free!
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December 8, 2010

Pros:

-works great if your body adapts to it
-cleared up my skin

Cons:

-induced lupus

Bottom line it worked great for me for two years. I was on and off. I took it for a year and cleaned up all my acne, I would never break out, only occasionally during my mestrual cycle. The second year I was on and off, only took it when I started having break outs. Three months ago I started having horrible pain on all of my joints and could barely walk or move my fingers. I would get that pain 3-4 days a week. Went to the doctor and they found out this medicine induced lupus and gave me all the symptoms of it so sadly I had to stop taking it. My pain is gone but started breaking out again:( Bottom line this is a great medicine if your body doesnt experience all the side effects, as you can see it worked for me just fine for 2 years. I do recommend it!
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March 22, 2010

Pros:

the first couple of weeks it cleared up my skin really well

Cons:

After 2 weeks my acne stopped getting better
I had some side effects that i wasn't ok with like sever headaches and vaginal itching and swelling

It worked well for the first couple of weeks but for me the side effects weren't worth what it was doing for me. So i am going back to my derm to try something different
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December 15, 2009

Pros:

Reduced bumps, redness, cystic acne, white heads, etc

Cons:

Gave me nausea at times

I have tried all the over the counter products, Proactiv/benzil/salycic acid/tee tree oil etc. I recently broke out bad, going from moderate acne, to severe.... and it was really getting me down and depressed (my confidence is usually never low) but I was experienceing very low self esteem. I recently went to the derm and he gave me minocycline and prednisone. I take one 100mg Minocycline and two 20mg Prednisone. I also use topical creams retin-A at night and metro gel, during the day. its my first week and I can see and feel a difference. I can at least now cover some of the redness up with my bare mineral ID (bare essentual) makeup (the only thing that doesnt make me break out). I hope this helpes for people out there wondering what to do about severe acne. I am waiting a few months then may start accutane so my acne goes away for good.
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March 20, 2016
Side effects.
Solodyn (Minocycline) side effects. Had a sebaceous cyst removed. After 14 days, was oozing some and doctor couldn't determine if was infected so gave some samples of Solodyn of 80 mg. Infection seemed to go away but was some seeping after I quit early because of other side effects. Didn't clear up any life long acne. When I quit, the acne got worse for about a month. After approximately 3 months, no change. SOLODYN left a greyish discoloration of the skin on my back of around 10 inches in diameter. Tiredness after approx. 5 days but didn't attribute that to the drug until more symptoms started to occurr including tighter tendons and muscles, the feeling moving fast might cause a charly horse in legs, a short headache (almost never get these), a few seconds of ringing in the ears (rare for me),woozy heavy head, chills(indicates fever) that I sweated out in one day, abnormal achy, spent more and more time in bed dragged down, my knees started to get sore (Not Normal at all), and vertigo when I rose from bed that would go away if I sat on the edge of the bed for a moment. Quit the meds 10 days in because it became clear they were deleterious. Started improving immediately but took about a month to feel totally myself again. I also took Probiotics to avoid diarhea which started to happen with this drug but went away afterwards if I took them daily. I kept taking probiotics for at least a month afterward to correct that. Read the paper that came with the bottle regarding side effects. Not just the back of the bottle! Some of my symptoms listed made me wonder how they line up with their side effects list. Capitals are what I experienced in the listed side effects.: -Intestine infection of watery DIARHEA. It kills all the beneficial bacteria which I found out later is a huge part of immunity. -Liver problems-Causes sleepiness & TIREDNESS. -Central nervous system effects-light headedness,dizziness and SPINNING FEELING(vertigo) -Benign intracranial hypertension-high pressure around the brain(,my WOOZY HEAVY HEAD),blurred vision,loss or UNUSUAL HEADACHES. -Auto Immune system-incl. a lupus-like syndrome'-'JOINT PAIN, FEVER,..MALAISE' And then they recommend testing? Just stop taking the stuff'. When I later read it can cause Lupus symptoms, I chastised myself for not reading the side-effects first. Who wants to gamble with your body like that? Then I read this stuff hasn't been evaluated in the treatment of infections. It's meant for inflammatory lesions of non-nodular moderate to severe acne vulgaris. I'm shocked that so many people are on it long term when the instructions say it hasn't been tested for more than two times at 14 days each with the mean age of the population at 20 years. It says 'The mechanism of action of SOLODYN for the treatment of acne is unknown', 'Long term animal studies have not been performed to evaluate the carcinogenic potential of minocycline. A structurally related compound, oxytetracycline, was found to produce adrenal and pituitary tumors in rats.'
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April 29, 2015
Quite good, Little to no side effects
I used this consistently for about 3-4 months, but my doctor took me off of it because you're not supposed to be on an antibiotic for all that long. I had severe breakouts around my jaw and chin and they were cleared up within a month or two. My Hyperpigmentation then took about 2 months to go away and I still have reddish tint/patch coloration which I know will also go away. Just remember to take it regularly and not to skip dosages. AND PLEASE get it from a real doctor and don't just order it off the internet.
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January 8, 2015
Thrilled
I had no results until about week 4 and I noticed I didn't have any new acne. Now at 6 weeks I am clear with only an occasional tiny pimple. This has been great for me.
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February 13, 2012

Pros:

This completly cleared up my acne. It was only moderate around my skin and forehead but something that I was very annoyed with.I have been trying out treatment for about the last 5 years (am 23). Am left with no scarring. Can go out with no make up. I take it before I go to bed at night. Have been on it for 7 months now.

Cons:

This cannot be taken within the same time period as other pills such as iron supplements. I is rather expensive.Paid €37 for a months supply. There are cheaper alternatives apparently but I'm sticking with what I know

It cleared my acne up withing a couple of weeks. Was told last week I had lovely skin. I haven't had any side effects.
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December 13, 2011

Pros:

Face smoother
Less Acne
Was free for me

Cons:

Seemingly gives me headaches once a day.

I am hardly a pro on this medication but I just completed 1 full week of being on Solodyn so I thought I'd share my story. I am a 29 year old male with adult acne. It was much more severe in my late teen years and a derm put me on Accutane for several months. It pretty much cured me and over the years I would get the occasional zit but nothing major like when I was a teen. Over the last year or so my acne seemed to be getting worse; to the point where I'd get several big zits a week. I got tired of it so I re-visited the same derm I had as a teen and after asking me some questions and looking over my face he prescribed me Solodyn. I have pretty good insurance, plus he gave me a coupon so I ended up paying absolutely nothing for the 30 pill bottle. I was told it didn't matter when I took the pill but I read reviews that it could make you tired so I always take the pill right before bed with some water. Over the first couple days I seemed to break out a lot but I've read that this med pushes all your upcoming zits to the surface so I didn't think much of it. Now after 1 full week my face seems to be more smooth and less red. I still have a couple zits that aren't fully healed/gone but so far nothing new in the last 4 or 5 days. As for side effects, I seem to get a headache in the mid afternoon since starting this med. I take some aspirin and it goes away but its kind of annoying. I haven't felt tired or anything like that but I'm hoping the headaches wear off eventually. Regardless, I'll tolerate a little pain for now as long as it keeps my face clear. I plan on re-reviewing this product after being on it for a full month. So far, I recommened it to those with moderate acne. It looks like most people are only on this drug for 3 months or less so I'm very curious if this will have lasting results like Accutane does. I guess I'll have to ask my derm some more questions on the subject since I'm a little more knowledgable on Solodyn now.
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September 4, 2015
did it work after getting off the medicine?

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.