Durante julio comence un tratamiento contra el acné (leve a moderado), la dermatologa me recetó 100mg de doxicilina por día, y un tratamiento tópico de adapleno 3 veces por semanas.  Al principio sentía que si me estaba funcionando, de hecho redujo la inflamación de mis lesiones.  el primer mes me llene de granos gigantes, eran muy dolorosos y mi piel estaba muy sensible, pensé que estaba en la fase de purga, de la que la mayoría de las personas hablaban. sin importar seguí con el tratamiento y mi piel se puso aun peor. Ya en el segundo mes comence a tener dolores de estomago y se hicieron mas frecuentes, mi piel seguia igual, se supone que el tratamiento era por 3 meses, ya cumpli los tres meses pero no veo ninguna mejora, de hecho siento que me dejo peor mi piel en comparación a omo estaba en el inicio. 

I wanted to write this review as you hear so many negatives on this site. A short background, acne since 12. Male. Tried minocycline that worked for approx 1year but had side effects. Went onto doxy at the beginning of December. Acne got worse. Waaaay worse. Kept taking 100mg a day (50 am, 50 pm ) everyday. Whiteheads kept forming. Scares seemed to take longer to heal. Hit 9 weeks and slowly less whiteheads (smaller in size) by week 10 scares started to fade. Week 11 - suddenly seems to be clearing. I think it’s a case of sticking with it as it works so slowly. Derm said deep cystic acne take 3 months to form so treatment takes the same time to heal. The plan is to reduce the dose over the next 3 months. Other changes are lots of water and fruit. Less milk and dairy. Advice: stick with it!

I have been prescribed this countless times over the four year course that I've had acne. This medication has not been successful in clearing my skin. Each time I have been prescribed this it was a three month trial. 

Other things to note are: that you CAN NOT take this while on Accutane. I had gotten an infection while at the beach and my Doc almost prescribed this while on Accutane. Huge hassle!

I had this treatment for cystic acne, but it didn't do anything for me unfortunately.

I was on this for 5 months and it did not clear me up. It gradually made me stop breaking out as frequently, but by the time that happened my dermatologist wanted to take me off of it. After that, my acne became worse and more resistant-- which makes sense now that I think about it  It kills the bacteria except for the resistant strains so after you finish the course, all you're left with is the resistant strain to break you out. This could be a good short term solution to give your skin a break to heal.. but if you don't see quicker results then it is not worth it to stay on it. 

all I gotta say...... is hell no. it rlly messed up my face and left a billion red marks up on me like wtf pill!!!!

I'm writing this review on Doxycyline because after 4 years of trying to cure my on and off cystic acne naturally or with only topical treatments, it has been the only thing to actually help so far. I've tried so many topical treatments as well as natural treatments for my skin. I was insistent on curing it without any pills. I became vegetarian for 2 years, constantly exercised, ate sugar-free, dairy-free, gluten-free, but nothing would completely clear my painful acne. My self-esteem went down and I found myself in situations where I did not want to leave my house. My whole life I've had very clear skin, except for the hormonal once a month zit. When I turned 18, my face began breaking out with small pimples. Skip to 4 years later and I have continued to break out on and off again with pretty bad cystic break outs and then my skin would be clear for a few weeks - then I would break out again. However, over the past 6 months, I had a mostly pimple-free face except that my face was super congested under the surface. I had small milia-like bumps that would not go away no matter what I tried. When I put on make-up, my skin was extremely bumpy and textured. I exfoliated, drank lots of water, tried several different products, cut dairy out and other unhealthy foods - but nothing worked. One day I was surfing the web and came across Retin-A (tretinoin). I started using it and within the first week, all of the bumps under my face surfaced and became these huge, cystic, pus-filled, RAGING pimples all over my cheeks, chin, and jawline. I read about the initial purging stage of tretinoin but I did not expect it to feel like a volcano erupted on my face. After breaking out with at least 2 new cystic pimples everyday for 10 days, I went to a dermatologist and he recommended pairing the tretinoin with Doxycycline. Long story short, I continued breaking out terribly for 2 weeks. During the first 14 days of Doxycyline, I kid you not, I did not leave my house AT ALL. I know this sounds extreme but my acne was THAT bad. By this point, I had at least 35 active pimples all over my face (except my forehead) and I could barely wash my face. I was literally just sitting in my house waiting for the doxycycline to kick in and clear up my face. Thankfully, by the 23rd day of persisting with Doxycyline, the left side of my face was completely smooth and all the small bumps underneath had gone. Yesterday marks 1 month on Doxycyclin and 1 month/10 days on tretinoin and all I am left with are a few tiiiiiny pimples on my right cheek and severe hyperpigmentation. However, my face has never felt this smooth in 4 years. I'm going to be on Doxycyline for another 2 months. I'm using the tretinoin to help with hyperpigmentation and the texture of my skin. I honestly don't know if it's going to come back after I finish 3 months but I'm really praying that it won't! 

Negative side-effects during my first 3 weeks:

1.) Loss of appetite 

2.) Nausea (if taken without food)