The following side effects are expected to occur with the use of tetracycline. Contact your doctor if these symptoms are severe and/or do not go away:
How Common (based on clinical studies)
|Nausea||Up to 16.8% of all users|
|Diarrhea or watery stools||Up to 8.7% of all users|
|Heartburn or indigestion||Up to 4.8% of all users|
|Pain in the upper part of the abdomen||Up to 3.9% of all users|
|Vomiting||Up to 2.4% of all users|
|Itching and irritation in the rectum or vagina||Up to 2.4% of all users|
|Irritated or sore throat||Unknown|
|Swelling of the tongue||Unknown|
|Black discoloration and hairy coating on tongue||Unknown|
Tetracycline may cause some side effects that are serious. If you experience any of the following, get in touch with your doctor immediately or seek emergency medical treatment:
- Pain in the chest
- Rash on any part of the body
- Swelling of eyes, lips, tongue, throat, or face
- Abnormal bruising or bleeding
- Signs of infection such as a fever or sore throat
- Severe headache
- Changes in vision
- A sudden appearance of swelling and rash (known as hives)
- Trouble breathing or swallowing
- Fever, abdominal cramps, watery stools or blood in stools either during or up to two or more months of treatment with tetracycline
- Swelling or stiffness of joints
Tetracycline may also cause other side effects that are not mentioned here. Contact your doctor if you experience any other troublesome symptoms when using tetracycline.
- UpToDate. Tetracyclines: drug information. Available from: https://www.uptodate.com/contents/tetracycline-drug-information?source=search_result&search=tetracycline&selectedTitle=1~150. Cited 27 February 2017.
- Gratton D, et al. Topical clindamycin versus systemic tetracycline in the treatment of acne. J. Am. Acad. Dermatol. 7, 50-53 (1982).
- Katsambas A, Towarkky AA, and Stratigos J. Topical clindamycin phosphate compared with oral tetracycline in the treatment of acne vulgaris. British Journal of Dermatology 116, 387-391 (1987).
- Norris JFB, Hughes BR, Basey AJ, and Cunliffe WJ. A comparison of the effectiveness of topical tetracycline, benzoyl-peroxide gel and oral oxytetracycline in the treatment of acne. Clinical and Experimental Dermatology 16, 31-33 (1991).
- Ozolins M, et al. Comparison of five antimicrobial regimes for treatment of mild to moderate inflammatory facial acne vulgaris in the community: randomised controlled trial. Lancet 364, 2188- 2195 (2004).
- Burton J, and The Dermatology Research Group. A placebo-controlled study to evaluate the efficacy of topical tetracycline and oral tetracycline in the treatment of mild to moderate acne. The Journal of International Medical Research 18, 94-103 (1990).