Oral Antibiotic
Reviews
3.2
1953 Reviews
Oral Antibiotic
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Should never be used on its own and for a maximum of 3 months.
Oral Antibiotic
Side Effects
High
Oral Antibiotic
Acne.org’s Real World Take
Antibiotics should be used for a maximum of 3 months, provide only moderate benefit and only to some people, and may lead to side effects and strains of resistant bacteria. Studies do show they can reduce severe acne in the short term, but approach with caution and stay your own advocate.
Oral Antibiotic
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Minocycline
Compare To Other Treatments
5
17.3%
4
27.7%
3
24%
2
16%
1
15%

Used Minocycline? Rate It:

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December 21, 2017
works for a few months
I started taking it in july and it worked great, by september i was only getting about 4 small pimples a month. But once it hit november it started to not work? i started breaking out as much as i would before i started taking it. So i went of it and started spironolactone.
June 13, 2017
Minocycline 50mg (Help?)
I've been taking Minocycline (50mg, oral) for about 2 1/2 months now Worked great at first, 50% of my acne vanished after the first week, and about 95% of my acne was gone by the end of the second week. For the next month and a half, I think I got a grand total of about three zits (which is a very low number for me), and I was very happy with the results. About a week and two days ago now, my acne has come back with one heck of a vendetta- I have twelve new spots on one cheek/jaw, more than that on the other, a few spots on my forehead around my eyebrows, and even a few spots on my cheekbones/under eye area (which is a place I have never previously gotten acne/had a problem with). My diet hasn't changed, I've been exercising exactly the same as I always do, wash my face with the same products as always, and haven't had any increase in stress levels (you know, except for the stress caused by the return of my acne). I was wondering if the minocycline could have stopped working after just 2 1/2 months, or if anybody has any other ideas as to why my acne may have returned? I do plan on going back to my doctor, but he can't see me for a few days, and my graduation/prom is the day before he can see me, and as that event was a big part of the reason I so desperately wanted to get my skin cleared up, I thought id reach out on and see what others have to say. Additionally, if anybody who has had a similar problem could share how they cleared their skin with me I'd really appreciate it. Additional and Background info: 18yo female. I have combination skin (dry/oily) that is pretty sensitive. Until about a year ago, I have never had more than a blemish or two, my skin was pretty 'normal' (perhaps a little on the dry side, but definitely never oily), and minimal redness (I'm pretty pale so my skin was always a bit 'pink' but now half my face is just...red). Out of what felt like nowhere, my skin turned awful, and I suddenly started getting blemishes. At first I'd have about four or five which at the time felt like my face was covered, and then my skin started to get oily too, and eventually more than half my face was covered in spots. More than that, before when I would get the odd blemish/spot, it would disappear without a trace, and now every spot I get leaves a scar...Does anybody know why that is? Anyways, I tried every face wash, acne cream, mask, cleanser etc. I could get over the counter that had worked for other people, I researched diets that were supposed to be good for your skin/help with acne, and I added supplements/vitamins meant to be good for your skin etc. Nothing made even the slightest difference. Skin to about nine months later, I finally went to see my doctor about it, and he prescribed the minocycline. I just want clear skin, and would appreciate any help I can get. Thanks.
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July 6, 2017
It could be that you've managed to cultivate a bacteria that is resistant to that particular antibiotic. Normally the way it happens is you either stop treatment too early, and the only bacteria that are still alive are the resistant ones, and then they multiply, or you forget doses, or don't take the whole prescription.
May 15, 2017
its ok..
My doctor prescribed me minocycline 100mg twice a day for about a month and a half. When I first took it, my stomach ached. After the first week, there was no results. In the second week, my skin broke out like CRAZY but in the third week, all my breakouts disappeared. My skin was clear until I finished taking it. As soon as I stopped taking it, my skin broke out on my cheeks and chin and it stayed like this till I found a new treatment. My forehead stays clear for some reason after I took minocycline. I WOULD RECOMMEND NEUTROGENA stubborn acne face wash. It cleared me up very quickly and did not break me out when I stopped using it!
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March 22, 2017
WORKED THEN STOPPED WORKING
IT WORKED GREAT when I first started taking it a year ago 100mg, I then was told by my Doc to take 50mg every other day to eventually get off of it because my skin was finally clear then it came back again milk nothing crazy so I went back to 100mg everyday and now my skin is the worse ever, zits on cheeks, and jawline this started in Feb this year, im on 200mg MONDAY-WED-FRI AND 100 MG ON TUES-THURS-SAT and so far Nothing my face is horrendous, im 32 years old and can't take Accutane so Im going to see a dermatologist in Toronto I heard shes one of the best so I hope whatever gets done WORKS and I stay clear!=(
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April 5, 2017
Please let us know what she says!
April 12, 2017
i saw the dermatologist today, she told me to stop taking minocycline my family dr should have not told me to keep taking it after 3 months, and I should have gone to see a dermatologist when I first started experiencing acne in my last 20's, anyways, she told me I have a severe case of acne, hard to treat which made me really disappointed to hear, I definitely was not expecting that =( she suggested I use her skin care line which I read is great expensive but great, I will stick to that but she also said I should do PHOTODYNAMIC THERAPY FOR ACNE, I read oneline, the super red face, discomfort, pain, swollen, peeling has worried me and pushed me away from even doing this sadly, I work in an office dealing with clients on a daily basis I cant look like I was burned alive it's horrible to even think of that, if there was no downtime I wouldn't be so worried, anyways, I called back and receptionist is going to have Dr (dermatologist) call me back tomorrow for an alternative treatment effective but no downtime if have to do a few more treatmetns than the photodynamic and it will help me I rather do that but I can't bare with pain and the suffering of this treatment, I know everyone is different but from what I have seen everyone turns beat red, sunborn gone bad and pain I just can't im very sad and stressed, I stopped taking minocycline I have since oct and feb was my worst month so I hope it stays the way it is until I find a treatment that wont make me suffer wish me luck=(
December 12, 2016
TC
I am on my fourth day of minocycline, and the nauseousness is at an all time high! I have also had migraine headaches for the few days that I've been taking it; accompanied with canker-like sores in my mouth (all new since starting this medicine). I will say that i have already noticed a small change for the better in the redness on my face, and things seem to be drying up and flaking right off. Now, if only i can deal with these horrible side effects I'm having.
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April 24, 2017
Take Vitamin C to avoid side effects, Cecon would be good to take twice a day.
August 28, 2016
Cystic acne
I've been taking this for several moths now,400mg.a day.I don't break out as much but I need help.I've had this problem for two years and I'm 62yrs old.some say use honey,apple cidar vinegar.HELP.I also take care of a husband with 11yrs in with Alzheimer's
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March 19, 2017
Gosh, I feel for you! That's a tough road. As a health coach, I've been putting my clients on lots of probiotics both topically and for digestive system. (Try VSL #3 or something equivalently strong). Paint face with plain kefir to re-instate good bacteria. Go off conventional dairy. Experiment a couple weeks with other common irritants (eggs, wheat, soy, canola etc). Drinking raw milk homemade kefir finally corrected my cystic acne at age 35! Before I even modified my diet.
June 17, 2016
It changed the color of my gums
I was on minocycline for about three years because my family doc refused to prescribe me anything else and refused to write me a referral for the dermatologist for the longest time. Minocycline worked kind of, but it wasn't any kind of miracle worker. I still had plenty of acne when I took it, but just a bit less. It also changed the color of my gums. It's not enough for me to notice, but it was enough for my dentist to notice the first time I visited him. I didn't notice any other major side effects. Overall it really isn't worth the time.
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April 28, 2016
please answer this question!
I am 13 and have been having acne for about a year. I tried a lot and my doctor just prescribed me solodyn. also onexton in the morning and ziana at night. I have been using this routine for about 10 days. I haven't seen much improvement. but I want to know does this product really work. and should I just give it some time? and if so how much time?
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July 15, 2018
I’m on pretty much the same thing as you! I’m also thirteen! I also take spironolactone and use a retinoid instead of ziana. I’ve been using it for about a month and seen a slow improvement from about 2-3 weeks, so It takes awhile you just need to be patient but if it comes to like 3 months and there’s no improvement talk to ur doc! You should be fine so far though!
April 11, 2016
Allergic Reaction to Minocycline.
I'm 16 and have grade one cystic acne on my face and back. I was just starting to see my acne clear up until 3 weeks into treatment when I had my allergic reaction. I have full body hives. I've had these hives for 2 weeks now, But they have shown a lot of improvement after taking Allegra Gel Caps for the 2 weeks and put on a 5-day 20mg prednisone pill. The hives were my only side effect, and they are virtually gone now, only some redness and heat remaining. I myself have questions on when it will resolve completely, but it can take time to get out of your system. I have also noticed my acne returning. This reaction only happens to one in one hundred people. I hope this is helpful to anyone having an allergic reaction to it or just looking for awnsers.
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April 11, 2016
No more breakouts, but I got sick ):
I started taking minocycline on February 13th of this year. 200mg a day. At first it didn't seem to do anything at all- I didn't even have any side effects from it at the time. It took a few weeks to see any progress but I noticed my cystic breakouts were shrinking and I wasn't getting any new ones. I'd still feel pain under my skin but nothing major. It was working but it wasn't as magical as some people's experiences. Unfortunately, I've been very sick for a while now. I got diagnosed with migraines with aura and on top of that I've been put on another antibiotic for an ear infection. It's hard to tell which of these three things is making me feel worse, but before I got put on the second antibiotic I noticed my tummy started getting upset so it can't entirely be the new antibiotic to blame, but I think it's certainly contributing to me feeling so sick. I take probiotics and eat ginger and nothing is helping the nausea and lack of appetite. I had zofran but even that didn't work so great. I feel awful and I don't know what to do but hey my skin is really smooth but just really red so now all I really need to do is heal. Hopefully I start feeling better once my skin is completely clear and I'm taken off of mino.

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.