Oral Antibiotic
Reviews
3.2
1954 Reviews
Oral Antibiotic
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Should never be used on its own and for a maximum of 3 months.
Oral Antibiotic
Side Effects
High
Oral Antibiotic
Acne.org’s Real World Take
Antibiotics should be used for a maximum of 3 months, provide only moderate benefit and only to some people, and may lead to side effects and strains of resistant bacteria. Studies do show they can reduce severe acne in the short term, but approach with caution and stay your own advocate.
Oral Antibiotic
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Minocycline
Compare To Other Treatments
5
17.3%
4
27.7%
3
24%
2
16%
1
14.9%

Used Minocycline? Rate It:

Choose from 1 to 5 stars
January 30, 2007

Pros:

Started clearing up skin.

Cons:

Pretty bad headaches for weeks and dizzyness

It started to clear up my skin in the first 2 weeks. But its hard because I sometimes forget to take my pill, dont drink enough liquid when taking it and the whole dairy thing kinda sucks. Its hard not being able to have dairy. I blame myself that I broke out and the pill stopped working. Im gonna ask my doctor to either up my dosage (I take 50mg 2 times a day)or try something else.
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January 28, 2007
I am a 16 year old guy and it is only recently that i have been forced to really find a way to treat my acne. up until about 6 months ago, i really didn't have all that much trouble with acne at all, aside from the occaisonal pimple. After i began to notice that my acne was worsening, i began using Spectro Jel to try and clear up my face a little. after about a month of very little results, i decided to see a doctor, who prescribed me clindoxyl gel. It worked great at keeping away any real noticeable pimples but i was still left with some pimples under my skin for some reason. i went back to my doctor, who prescribed me Retin-A 0.025. It worked great on the pimples that remained under the skin but i stopped using it cause it made my face red and dry. About a week ago, i was perscribed minocin to go along with my regular clindoxyl and spectro gel. So far the only complaint i have is that post-workout recovery seems to be more strenuous than it used to be. Minocin is helping great though
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January 1, 2007

Pros:

Since taking, I have not had any new breakouts and my existing acne reduced in redness and swelling

Cons:

afraid of what will happen when use of this product is discontinued

It is working great right now. I have had no luck in treating my ADULT acne until now.
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December 10, 2006

Pros:

I don't think I was on it long enough for it to work.

Cons:

I developed a bad case of hives, which I am now in my fourth day of, and even though I'm on steroids and Benadryl, they won't go away.

I would not take this medicine if you have ever had a problem with an antibiotic. I am allergic to some other antibiotics and I think that maybe this indicates a hypersensitivity to them. Be careful - hives are no fun!
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October 30, 2006

Pros:

Nothing yet, it's been a month and my skin is very very slowly improving. The minocycline hasn't kicked in yet, improvement probably due to toner used.

Cons:

I think the minocycline is drying out my face and my eyes feel dry. If it is supposed to slow down oil production, that's great because I have oily skin.

It does not work quickly. I was told to wait 2 months for improvement so that is why when I read some of the "it helped in a few days" reviews I was confused. I hope it starts working soon. For the people who have been on it for months, how long was it from the start of taking minocycline to the what seems to be very far away bliss of clear skin?
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October 24, 2006

Pros:

Cleared up my acne and gave me beautiful skin.

Cons:

When I came off it, the acne returned--and no other drug has worked since.

Minocycline worked for me the first time, when I was 18-19. But then my dermatologist took me off it for no given reason (my usual doctor was puzzled too, since I'd experienced no side effects --apparently the drug can cause liver problems if taken for too long, but these are usually monitored with blood tests. Dermatologist was, therefore, being over-cautious). I tried other antibis, and the contraceptive pill too, but none of them worked. Eventually, after much begging, I was given Minocycline again--but this time, it didn't work. It seems this drug is effective only when taken regularly. If you can persuade your doctor to give you a permanent prescription, then go for it. Price below is approximate: it's now £6.65 for a prescription on the NHS.
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July 24, 2017
Cleared skin
Definitely take it with a snack when you take it because it might upset your stomach if you don't. Other than that, I had no problems with this med! I was on it for quite some time last year and then stopped taking it because I don't like being on anti-biotics for more than 3 months. My skin was fine though, and I like how if I have a flare-up, I can just take a few and my skin improves quickly!
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July 5, 2017
Not worth it I promise
I was on Minocycline 100mg 1qd for the first week and 1bid for 3 weeks before I developed an allergic reaction which was serum- like sickness. I had swelling and hives that mainly on my joints for 5 DAYYYSS!!! It started on Saturday, On Sunday my bottom lip started to swelling on Sunday and I knew it wasn't a big deal because if it was going to spread to my throat it would have happened fast but everyone insisted I go to the hospital, which I did and they prescribed me Prednisone 60mg 1qd for 3 days and Hydroxyzine 25mg 1tab po every 6 hr prn for itching well its Wed. still itching like crazy! but no cystic acne as of yet it's been 5 days since I've took then antibiotic I do not plan on starting anything like it again.... if this didn't work my derm. Wanted to do Accutane but after this I rather just have acne.
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June 13, 2017
Minocycline 50mg (Help?)
I've been taking Minocycline (50mg, oral) for about 2 1/2 months now Worked great at first, 50% of my acne vanished after the first week, and about 95% of my acne was gone by the end of the second week. For the next month and a half, I think I got a grand total of about three zits (which is a very low number for me), and I was very happy with the results. About a week and two days ago now, my acne has come back with one heck of a vendetta- I have twelve new spots on one cheek/jaw, more than that on the other, a few spots on my forehead around my eyebrows, and even a few spots on my cheekbones/under eye area (which is a place I have never previously gotten acne/had a problem with). My diet hasn't changed, I've been exercising exactly the same as I always do, wash my face with the same products as always, and haven't had any increase in stress levels (you know, except for the stress caused by the return of my acne). I was wondering if the minocycline could have stopped working after just 2 1/2 months, or if anybody has any other ideas as to why my acne may have returned? I do plan on going back to my doctor, but he can't see me for a few days, and my graduation/prom is the day before he can see me, and as that event was a big part of the reason I so desperately wanted to get my skin cleared up, I thought id reach out on and see what others have to say. Additionally, if anybody who has had a similar problem could share how they cleared their skin with me I'd really appreciate it. Additional and Background info: 18yo female. I have combination skin (dry/oily) that is pretty sensitive. Until about a year ago, I have never had more than a blemish or two, my skin was pretty 'normal' (perhaps a little on the dry side, but definitely never oily), and minimal redness (I'm pretty pale so my skin was always a bit 'pink' but now half my face is just...red). Out of what felt like nowhere, my skin turned awful, and I suddenly started getting blemishes. At first I'd have about four or five which at the time felt like my face was covered, and then my skin started to get oily too, and eventually more than half my face was covered in spots. More than that, before when I would get the odd blemish/spot, it would disappear without a trace, and now every spot I get leaves a scar...Does anybody know why that is? Anyways, I tried every face wash, acne cream, mask, cleanser etc. I could get over the counter that had worked for other people, I researched diets that were supposed to be good for your skin/help with acne, and I added supplements/vitamins meant to be good for your skin etc. Nothing made even the slightest difference. Skin to about nine months later, I finally went to see my doctor about it, and he prescribed the minocycline. I just want clear skin, and would appreciate any help I can get. Thanks.
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July 6, 2017
It could be that you've managed to cultivate a bacteria that is resistant to that particular antibiotic. Normally the way it happens is you either stop treatment too early, and the only bacteria that are still alive are the resistant ones, and then they multiply, or you forget doses, or don't take the whole prescription.
March 22, 2017
WORKED THEN STOPPED WORKING
IT WORKED GREAT when I first started taking it a year ago 100mg, I then was told by my Doc to take 50mg every other day to eventually get off of it because my skin was finally clear then it came back again milk nothing crazy so I went back to 100mg everyday and now my skin is the worse ever, zits on cheeks, and jawline this started in Feb this year, im on 200mg MONDAY-WED-FRI AND 100 MG ON TUES-THURS-SAT and so far Nothing my face is horrendous, im 32 years old and can't take Accutane so Im going to see a dermatologist in Toronto I heard shes one of the best so I hope whatever gets done WORKS and I stay clear!=(
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April 5, 2017
Please let us know what she says!
April 12, 2017
i saw the dermatologist today, she told me to stop taking minocycline my family dr should have not told me to keep taking it after 3 months, and I should have gone to see a dermatologist when I first started experiencing acne in my last 20's, anyways, she told me I have a severe case of acne, hard to treat which made me really disappointed to hear, I definitely was not expecting that =( she suggested I use her skin care line which I read is great expensive but great, I will stick to that but she also said I should do PHOTODYNAMIC THERAPY FOR ACNE, I read oneline, the super red face, discomfort, pain, swollen, peeling has worried me and pushed me away from even doing this sadly, I work in an office dealing with clients on a daily basis I cant look like I was burned alive it's horrible to even think of that, if there was no downtime I wouldn't be so worried, anyways, I called back and receptionist is going to have Dr (dermatologist) call me back tomorrow for an alternative treatment effective but no downtime if have to do a few more treatmetns than the photodynamic and it will help me I rather do that but I can't bare with pain and the suffering of this treatment, I know everyone is different but from what I have seen everyone turns beat red, sunborn gone bad and pain I just can't im very sad and stressed, I stopped taking minocycline I have since oct and feb was my worst month so I hope it stays the way it is until I find a treatment that wont make me suffer wish me luck=(

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.