Oral Antibiotic
Reviews
3.4
1734 Reviews
Oral Antibiotic
Efficacy
56%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Should never be used on its own and for a maximum of 3 months.
Oral Antibiotic
Side Effects
Medium-High
Oral Antibiotic
Acne.org’s Real World Take
Antibiotics should be used for a maximum of 3 months, provide only moderate benefit and only to some people, and may lead to side effects and strains of resistant bacteria. Studies do show doxycycline can reduce severe acne in the short term, and as far as oral antibiotics are concerned, it’s usually the go-to, but approach with caution and stay your own advocate.
Oral Antibiotic
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Doxycycline
Compare To Other Treatments
5
20.7%
4
32.9%
3
22.1%
2
12.7%
1
11.5%

Used Doxycycline? Rate It:

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November 26, 2011

Pros:

Clears skin
Low cost

Cons:

Mild nausea
May lose effectiveness
Can't take forever

I was put on a regimen of doxy, benzaclin, and tretinoin and it's worked very well. The idea behind the doxy is not to take it forever, but to mitigate the initial breakout which results from using the tretinoin. Being an antibiotic, the longer you take it, the larger the population of antibiotic-resistant bacteria on your skin (and in your body) will dominate, because you are selecting for their growth (by constantly eliminating non-resistant bacteria). This always results in the drug eventually not working. I don't think many dermatologists prescribe this drug by itself anymore because it's not really a long-term option; they do it to buy you some time. You do get some nausea with this drug. I would say I have a pretty strong stomach, but even I'm reluctant to take this on an empty stomach. But I can't really complain about the results because IT DOES WORK (at least for me). Eventually your dosing will be reduced from twice a day to once a day, and maybe once every other day. The dermatologist doesn't want you on this for a long time because it makes you susceptible to stuff like pneumonia, or if you need antibiotics to treat illnesses in the future.
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November 20, 2011

Pros:

Clears skin pretty quick.
Very Cheap

Cons:

Yeast Infection
Neausea

READ THE DIRECTIONS ON THE PACKET GIVEN TO YOU BY THE PHARMIST BEFORE YOU TAKE THIS MEDICAN!! It says do NOT take it with anything dairy. If it makes you sick when you take it on an empty stomach, eat with it [remember, nothing with any dairy]. Make sure to drink A LOT of water. And also DON'T lie down for 30 minutes after you take it. Wait 2 hours after taking doxy before you take any antacids, vitamins, or calcium products. This is a good drug for acne but no one is taking it correctly and it's getting bad reviews. Take the full prescription until your doctor says so, because if you stop, the infection can come back and you can become immune to the antibiotic. Basically, Doxy worked for me, and I had very sever foliculicus.
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October 26, 2011

Pros:

Clears skin

Cons:

Haven't had any at all

Cleared up my pimples within 10-14 days and break-outs have stopped coming back. I have 2 months left on my prescription so I hope when i've finished it doesn't come back... Overall, great pill and haven't had any side affects as I take it with my lunch sitting up. Alot cheaper in Aus too.. Only $10 per month!
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September 9, 2011

Pros:

None

Cons:

Horrible yeast infections

It didn't clear my acne at all and caused yeast infections that i had to fight for at least 6 months. The worst time of my life. Maybe it does help somebody, but I would never ever recommend it to anyone. Bactrim, in contrast, cleared my acne overnight. But unfortunately, it's also an antibiotic.
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August 7, 2011

Pros:

clears up persistent acne

Cons:

f**ks up your system in the long run, probably the same extent as accutane

try it out. you will purge for a week and half or so but it will clear up. if you don't have the money to go see a derm EVERY DAMN MONTH, go to a travel clinic, tell them you already got all the vaccinations for Nepal, and that you just lost the prescription for malaria pills that the "previous" doctor gave you. tell them you will be gone for half a year. voila. you have a half a year's worth. work the system. otherwise, you'll be paying a sh*t ton if you dont have insurance. its what i do.. :D just got my new prescription last thursday
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July 21, 2011

Pros:

actually worked really well, easy to use, helps a lot with deep painful pimples, clears face 98%.

Cons:

doesn't work forever, body becomes immune to drug, causes nausea if taken on empty stomach, doesn't work if taken with milk before and after 1 hour.

basically I have had acne for a very long time. I've tried a lot of things to at least tame my acne. nothing really worked. I finally decided to seek help from a doctor. I wanted to go onto accutane but my doctor wouldn't let me since my acne wasn't severe enough. he prescribed me doxyclyine. it worked amazingly! I was so happy. my acne was finally under control. it worked all throughout my final year of high school but right around july it started to come back. I recently found out that I've most likely become immune to the drug. very sad! so overall great drug, but not a forever thing which is disappointing to say the least. I am going to try a different antiobiotic and I'm hoping I will have the same results. if not, accutane here I come!
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July 6, 2011

Pros:

none

Cons:

it didn't have any effect on my acne

I've been on doxycycline for a month, and my skin is still breaking out. I took it everyday, used a benzoyl peroxide wash and a moisturizer, and still NOTHING. I really wanted it to work, but sadly it didn't.
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March 9, 2011

Pros:

Clearing up my Acne

Cons:

Nothing yet (only the 5th day so far)

I am 29 years old and i haven't had the best skin in my days. But i will have t say it has been nothing like what i've been going through the past year. I started getting these little tiny bumps under the skin first. And then the cystic ones started popping up around my jaw line. It has been horrible. I haven't wanted to go anywhere or do anything. It has really put a damper on my self esteem.I am hoping this medicine will work. I need to get out of this funk i'm in. I have three kids that need their mommy to be active. The only prblem is now i feel like i'm gaining weight. I have been on this medication for 5 days so far. I have gained 6 pounds since i started. I'm not positive if its the medicine but i do workout and I don't understand why i haven't lost anything. Is anyone else having this problem? If this medication gets better and I start to notice more improvements and lose these love handles i'll rate higher.
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December 10, 2010

Pros:

Kept Me Clear for about 4 Months

Cons:

Natural resistance after a period of time, and then acne came back worse than EVER

I began taking this August of 2009. By September, my light/moderate acne was clearing up. During October, my skin was a dream for the most part, minus one or two persistant blemishes. November, fine again. Then December rolls around. I notice my skin forming small break-out "areas." Not worrying, I kept taking my Doxycycline religiously. It all went downhill from there. I either needed to up my dosage because my acne bacteria had "morphed" and conquered this particular anti-biotic or I had to switch to something stronger. It wasn't until March, after my skin was now covered in SEVERE acne that I stopped taking it, and out of desparation, went to go see a dermatologist and a gynocologist. It has taken me one full year to get my skin back to clarity. I will never treat my acne with antibiotics again.
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April 25, 2010

Pros:

Cleared up my milia

Cons:

acne comes back slowly

I didn't' take this antibiotic for acne but for something else but while i was taking this for a week, i did notice that my forehead acne (milia) was going away. I have acne on my cheeks and my forehead but since my cheek acne was already under control by benzoyl peroxide I was not able to know if it was clearing my cheek acne as well. However i think this was definately affective for my acne. Took this morning and night for a week.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.