Topical Retinoid
Reviews
3.2
1910 Reviews
Topical Retinoid
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid
Side Effects
Low
Topical Retinoid
Acne.org’s Real World Take
This topical retinoid medication provides partial relief at higher prescription dosages, but don’t look for complete clearing. Relatively affordable and comes with less side effects than tretinoin, the other affordable topical retinoid. As a bonus, it improves the look of skin and reduces fine lines and wrinkles a bit too.
Topical Retinoid
How to Get It
Adapalene is available in strengths up to 0.3% by prescription. Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one. Adapalene is also available over-the-counter in 0.1% strength. Here are some places you can find it online.
Read All About Adapalene
Compare To Other Treatments
5
17.5%
4
30.4%
3
22.6%
2
17.1%
1
12.4%

Used Adapalene? Rate It:

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September 16, 2014
1 month in...
I took Accutane and my skin stayed clear for 1.5 years. During this time I was just using normal face wash and Aczone prescription, exfoliating, etc. About a month ago my skin just went nuts. It started getting really oily and I started noticing a considerable increase in "congestion". I had lots of blackheads and absolutely riddled with closed comedones. My skin overall and had an extremely oily and bumpy look to it, but wasn't breaking out into inflammed zits. So like I said, about a month ago I went back to the derm and she suggested Differin. She mention Aczone will not address the bumps under the skin, but Differin will. She suggested I continue using Aczone during the day, but Differin at night. The first week my skin went nuts with large zits and some cystic acne, which I have not had since pre accutance. Now that I am in what I think is week 4 or 5, the big zits are gone, but it's like every single bump on my face is red. Red acne scars have also been taking FOREVER to fade. It's absurd. I've read Differin "purges", but is this normal?
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September 14, 2014
just be patient ^_^
It really works from me, i'm using it for about 2 months (april and may) and stop and my blackheads on my nose came back. Then I decided to use it again I have been it from now for almost 1 week and my face starts to clear it again. I do have oily face and no need to use a moisturizer except for applying non comedogenic sunscreen like cetaphil in morning. For my facial wash, I've been in a trust of benzac daily foaming wash which is supposed to be in acne oily facial skin and its true ^_^ then after washing I apply soothing toner with aloe vera and chamomile extract you should do this every morning afterwards apply sunscreen. In evening just wash your face with your facial wash then apply a thin coat of differin gel.. and thats it ^_^
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September 14, 2014
A friggen miracle
This stuff has worked wonders for my face! This is gonna be a long review (don't say you haven't been warned)! I used to have moderate acne with occasional bouts of cystic acne. I had visited my dermatologist about two years ago and she prescribed me Retin-A. It had worked for my mother when she was my age, so I figured it would be the same for me. I was oh so very wrong. I stuck with Retin-A for almost 3 months, and in that time, my acne not only failed to improve, but got drastically worse. Instead of occasional appearances of cystic acne, it became a regular presence on my face, particularly my cheeks. Eventually, I stopped using the stuff, and I thought my skin would start to heal itself. Unfortunately, Retin-A seemed to have done more than I thought, and normal zits would form on top of deep, cystic zits. I didn't want to start back on Retin-A, and I didn't want to keep doing nothing, so, I called my regular doctor and scheduled an appointment with her. I told her that my dermatologist had prescribed Retin-A and had resulted in the warzone that was my face. My doc told me to try Differin. As skeptical as I was, my skin had gotten to the point where it was painful even when nothing was touching it. So, I picked up a tube. It was the best decision of my (dermatological) life. Within a week most of the surface acne was gone, and some of the cystic acne had started to heal as well. By the end of the third week, the majority of my acne was gone (except for a few blackheads on the nose), and the scars from my disastrous Retin-A experience (both psychological and physical) had even started to fade. I still use Differin today, on and off. Even when I'm not using Differin every night, my skin stays relatively acne free. When I am using Differin, my skin is practically pimple-free. Seriously guys, Differin works (well, for me, anyways).
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September 12, 2014
The worst
I cant stand this gel, it leaves my face burned!! it hurts so much.
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August 24, 2014
Good product, but you have to be patient
Differin or adapaleno is a good product, but You have to be patient, and persistent if you wanna see change. Don't give up and continue using this product if you are in the 3rd month, because is when this product begins to work. I have 8 month using adapaleno and clindamicin and mi face is much better, My acne was moderate, and now I just have a few blackheads. I'm so happy now :D, and remember you are beatifull in your way. Ah! Sorry for my english, I just speak a little bit.
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December 30, 2016
Did you use 0.1 %?
August 24, 2014
Pointless
I honestly do not know why I was prescribed this medication; it literally did nothing for my acne; made my acne worse. Caused more blackheads/clogged pores.
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August 19, 2014
Drastically Worsened Acne
I have suffered on and off with acne for my whole life. I had previously cured my (relatively mild) acne with gentle skincare regime and benzoyl peroxide. Eventually I stopped using the benzoyl peroxide treatment and in 5-6 months my acne started to return in the form of bumps under my skin which I initially thought was a reaction to a product. This progressed to a few active spots and breakouts; seeing that my acne may be returning I went to my GP. He was concerned that either my acne was returning or I had a bacterial infection and so prescribed my a Tetracycline antibiotic and Differin. I used Differin for around 6 weeks before I couldn't take it any more. I know this product is a retinoid and can cause skin "purging" but this was way beyond that. I would wake up to increasingly inflamed, reactive skin and cystic acne and whitehead breakouts in area's I had never previously broken out in my life. Eventually the amount of scarring and hyper-pigmentation this stress on my skin was causing became too much and I quit the treatment. After a gap of around 2 weeks I have since begun treatment with Duac 5% Benzoyl Peroxide cream. It has been 3 weeks and already my skin is starting to show some improvement. Please be careful with Differin, it ruined my skin.
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August 16, 2014
Not sure
I'm 24 have had acne on and off since a teenager trying lots of different creams anti-biotics... Last years before Christmas I had an extremely bad break out of acne over my face, chest and back after trying a a couple of different treatments eventually i found the antibiotic Oxytetracyline after about 3 months if being on it my skin cleared I am still carrying it on in fear it will come back. In this time I went to a dermatologist and this is when she recommended differin adapaline to carry on long time during and after my antibiotic course. The problem is I have tried a couple of times to start this product out the longest I have lasted is about a week as my skin seemed to get flaky and try break out even more... Is it worth me sticking it out through this. Also I do used sun beds every other week or so and I will struggle to give this up, help?
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August 14, 2014
Wonderful
I'm not one for writing reviews so bare with me; this might be long. I have suffered with acne since the end of my freshman year of high school. I went to the derm. right away because I did not want to go through having severe acne for years. Right away he prescribed Epiduo. That wrecked my skin and made it dry, itchy, RED, and bumpy. It was horrible. So he the prescribed Ziana. This was not aggressive enough and made my skin oily and pores huge. Next he prescribed Aczone and Solodyn (the pill). I had such high hopes and unfortunately this treatment didnt work either. I then took birth control for personal reasons and I knew people whose skin cleared up from taking it. Unfortunately this made my hormones crazy and my acne worse. By this time I was a junior in high school still struggling with mild/moderate acne and I felt like nothing would work for me. I decided that the derm. couldnt prescribe anything that would get rid of my acne so I was going to make my own treatment. I started eating better and using only organic face products. I realized that the problem was likely hormonal/genetic so i would either have to use some type of prescribed treatment or just wait it out until I grew out of my acne. I was feeling so insecure and I absolutely hated my skin. My whole high school experience was plagued with this embarrassing thing I had on my face. I felt like no one would want to talk to me because of it. Of course now I realize that acne doesn't make a person. Often times we see our flaws as much worse and if you are struggling with acne you need to understand that your acne should not control you. The summer before my senior year I made a goal for myself: clear my acne! I went to the derm and he said that Differin Adapalene would benefit my skin. So I believed him and began using that every night on my face as well as taking the pill Doxycycline. Let me tell everyone, the first month for me was very rough. I struggled a lot with even leaving the house. My acne was the worst that it ever had been but since it was summer I didn't have many obligations. The hardest part for me was not the acne itself but it was my confidence. I had zero confidence and I didn't want anyone to see me. Luckily, after that first month my acne began improving! This happened slowly. The acne marks and scars started to fade and any bumps I would get were very small and would heal quickly. I am still dealing with some scars but I am happy with the results and I truly believe that it will clear my skin all the way. Be patient with this product! Don't give up on it because if Differin is right for you it will all be worth it! Hang in there.
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August 10, 2014
8 weeks in
I'm 20. My doc prescribed me Differin and Doxycycline Antibiotics for my mild acne. Well. It's been 8 weeks and my acne has moved from mild to moderate and I have more pimples than when I started the Differin. The doc said to take it for 3 months but I doubt that it will start producing any results in the 4 weeks I have left. This has left me extremely frustrated. I really thought this would work because for the last 4 years I have been using over-the-counter products like Benzoyl Peroxide and this was the first time a doctor looked at my acne. I feel like these last 2 months on DIfferin were a waste of time, money and effort.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.