Ziana : Clindamycin (1.2%) and Tretinoin (.025%) Gel

Brand:
Reviews
3.4
474 Reviews

Active Ingredients:
Clindamycin Phosphate (1.2%) and Tretinoin (.025%).

Inactive Ingredients:
Purified water USP, glycerin USP, carbomer 981 NF, methylparaben NF, polysorbate 80 NF, edetate disodium USP, citric acid USP, propylparaben NF, butylated hydroxytoluene NF, and tromethamine USP.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

5
24.9%
4
30.6%
3
19.6%
2
12.2%
1
12.7%

Used Ziana : Clindamycin (1.2%) and Tretinoin (.025%) Gel? Rate It:

Choose from 1 to 5 stars
August 4, 2008

Pros:

I have been on it a week, and it has cleared my face up significantly....

Cons:

My face is so dry, it's peeling, cracking, and hurts to the touch or even if I wash it with no soap and just water....

The vote is still out for me....I have dry skin, and peeling up to my eyballs, everything, and I mean everything that I put on my face goes through about twenty to thirty minutes of burning before it will calm down, including water....I have been on it a week, and I can tell my face is clearing up, and I don't really see any color changes with my skin, but I don't know how much of the dryness I can handle...I go back to the doctor in about 2 weeks, and I will see what he says about what kind of facial moisterizers I need to use because this is really really really bothering me....
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July 17, 2008

Pros:

Helps acne a little... not much

Cons:

Causes VERY oily skin and doesn't really help acne that much.

Ziana really wasn't helpful in terms of clearing acne. At first my skin broke out a lot which was to be expected. I was told it could take up to 8 weeks. Even at that point my skin still had acne on it. At 10 weeks I had my dermatologist appointment again and we decided to switch to Differin. It had the same major ingredient but at .3% (opposed to .1%.) I have been using it for a week now and it has been great! I think people who use the major ingredient at .1% don't see good results while at .3% get great results. This will cause your skin to dry out but some moisturizer and you'll be all set. Something else: When using Ziana my skin became very VERY oily. 30 minutes after washing my face the oil was already built up on my face. I'm not sure why Ziana caused this but this incredible oilness made me hate it to begin with. I wouldn't recommend Ziana. I WOULD recommend Benzaclin and Differin in terms of tropical creams. In terms of antibiotics minocylin
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December 31, 2007

Pros:

Not as drying as some topicals

Cons:

Doesn't work, very expensive

Didnt notice any difference at all and it was over $300 dollar without insurance. Now Im stuck with a half used tube of worthless clear gel.
December 31, 2007

Pros:

none really

Cons:

started to clear up after a week or 2 for about a week then took a turn for the worst...hasnt cleared up at all since, only gotten worse

ive been on this for 3 1/2 months. .and my face has only worsened since i started it. and the worst part of it all is im getting married in 5 months--and i was told this would for sure work. so im bummed. :( hoping something else might work....maybe benzamycin?? not too mention i had to pay out of pocket because i have a high deductible and it was $275.00 for me. too much for it not to work. cause if it did work id pay it in a heart beat
October 27, 2007

Pros:

it was free..the derm gave me samples

Cons:

my skin has never felt so unhealthy. Still breaking out. Dry and peeling like crazy!

Nightmare!!!
October 18, 2007

Pros:

It didn't cause me to break out in hives and I noticed no adverse reactions in about 3 weeks of using it.

Cons:

There was a slight drying of skin and a strange odor which left my pillow smelling like the medicine. In the morning, I noticed bits of what looked like dead skin on my face. Not sure what that was!

Don't use a lot of this product if your skin is sensitive! Do the recommended dose or your skin will probably dry out as much as these other people state. I did one limabean-sized (bigger than a pea-size I know) for the "4-dot-areas" on my face, a pea-sized dot for my neck, and then a pea-sized dot for each shoulder and I never suffered extensive peeling or drying. In fact, I'm pretty sure the possible side-effects list the drying, severe redness, and peeling to be a sign to STOP using this product. If you follow the directions on the package (i.e. washing your face before application, waiting until your face is completely dry before applying, and then using the recommended amount) then you will probably use this product with no problems. I used it for a combined 3 weeks before I was told to stop and try something else based on an allergic reaction I had to Minocycline. This stuff was expensive even with good insurance but my doctor gave me a $30 rebate so I was happy
October 13, 2007

Pros:

not AS harsh as it's Retin-a counterpart
If you rub it in, it is invisible

Cons:

It is still pretty abraisive and burns
Isn't really that powerful
Have to apply it to entire face, it HURTS

It may be effective for some acne, but not mine. I have had more luck with OTC than the various Rx's that my dermotologist has prescribed me.
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September 5, 2007

Pros:

Does not burn like Tretinoin Gel/Retin-A Gel.

Cons:

Did not calm down the cystic acne. Not as effective as Tretinoin. Very expensive--my health plan didn't cover it all that much so I paid $112.75 for a tube.

Not worth it, except if you have mild acne. Not good for cystic acne.
August 22, 2007

Pros:

Helps clear up large inflamed zits

Cons:

unbelievably drying and sooo harsh!

My skin is not usually sensitive at all and I have used other retinoids in the past such as tazorac. But this stuff tore apart my face. I followed the directions exactly but after a couple of days my face became so dry that it started to crack! I felt like I was wearing a facial mask for about a week and my skin was as red as a tomato! It hurt so much and I couldn't even go out of the house my skin looked and felt so terrible. I called the derm and he told me to switch to only using it every 3 days and slowly work up to using it every day. Although the irritation has subsided quite a bit it is still making a mess of my face even though it's been nearly a month!!! I only really have a couple of zits left but my skin still looks horrendous because this stuff has left marks that look and feel like burns!!! I'm so afraid they are going to scar! I was so much better off before this. I'd rather have some zits than what looks like chemical burns.....
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June 24, 2007

Pros:

Once-a-day application.

Cons:

High price ($50+ copay per tube, w/list price of $250+)
Causes acne to worsen initially (was warned about this by derm)
Takes 6 weeks to see improvement (according to derm)

This product DID NOT work for me. In fact, it made my mild to moderate acne much worse. When I start using Ziana, I would say my acne was about a 3 on a scale of 1 to 10. After 6 weeks, I'd have to say it's now a 7 or 8. I expected some degree of initial breakout, but after seeing my acne get so much worse during treatment, I now have to try to clear new lesions. To add insult to injury, this product also has made my skin severely oily -- to the point where it is making my hair oily by the end of the day. Definitely NOT recommended.