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Welcome back BRD 🙂 i hope you update us with your results and the latest protocol you're following.v_singh, do you have any letters or a neat document which describes the adult stem cells procedure clearly. I would also like to share it with my dermatologist. I'm not sure if she will be interested or not, but I would like to try. Anyway, let me know please if you or any1 else has something good to share with doctors. Thanks a lot 🙂
Hi unknown,
I am basically performing the very same procedure I described before. Long term I am considering the use of gene therapy (ie: Wnt pathway regulation), although this will be something that I will not incorporate commercially for at least another 3-5 years, if ever. After all, surprises in the form of new discoveries are almost always hidden behind every corner and they're revealed to us at an increasing pace, which makes it that much more difficult to accurately extrapolate current trends and likewise use them to predict the future. Most of the time new scientific developments allow us to incrementally improve the way we treat patients, but sometimes they completely shock us and cause a paradigm shift. Regenerative medicine as a field is experiencing an exponential growth of its knowledge base coupled to an unparalleled technological convergence rate. This means (pardon for stating the obvious) that what we know today is very limited relative to what we'll know tomorrow. You can read about new advances every single day of the week. Sometimes what seems like an incredible solution in 2009 may be replaced by something far more potent in say 2013 that was likewise discounted as pure science-fiction or even impossible just a decade earlier. Such are the times we live in. It's going to get pretty wild as the passing scenery becomes nothing short of dizzyingly blurry... Mark my words. 😉
BRD is there anyway you could PM me with the exact steps and procedures involved. I am seeing someone in 2 weeks and would like to provide them with this to see if they would consider implementing it?Would really appreciate any guidance as I do not want to raise something without really having any idea and right now I could not explain it myself without something set out.
Cheers
Hi otis20,
Did you get a chance to see what I wrote in post #551? I believe it may contain the information that you're looking for.
Dear Bulgarian Doctor,do you think your recommended therapy would bring other or better results when you use stem cells won from fat? Isnt the concentration of mesenchymal stem cells in fat higher than in blood?
Thanks for answering, loulu
Hi Loulu77,
I actually use adipose derived mesenchymal stem cells, although a small number of peripheral blood stem cells are also indirectly involved in the enhanced procedure I've been talking about.
Hi BRDCould you please PM me. I have the notes of my preocedure that I would like to discuss with you.
My skin was not red after treatment as was the case with the two other patients on this board. In fact I could leave the house immediately after, no prob, except I was puffy. I stayed with a doctor friend after the treament and he even said there were no injection sites other than where the fat was inserted.
So to answer your question there was no:" ( a ) needling, ( b ) subcision and ( c ) PRP injections before transplanting the ADMSC."
Remember, I was one of the very first to get treated so perhaps the doctor was still trying out new procedures. It is all trial and error with these new procedures.
Thanks very much!
Hi heidi55,
I'll PM you tomorrow and we'll go over a few things. Bye for now.
An update for those considering Stem Cell Treatment... get it done!It's been almost 2 months since I had my treatment and I'm very pleased with the results. My skin isn't perfect and I still have some red marks but there is a huge improvement to both the look and texture of my skin. Apparently the best results are seen after 3 months but even at this stage I would say it's well worth it. With makeup on I don't even think about/stress over my skin anymore. I'll do a full report in a couple of months with some before and after photos.
A note to someone on here who discredited Dr Khan... his clinic isn't a charity! It's in Harley street so the rent alone on that place must be astronomical. He also has to pay for time spent in hospital for surgery, equipment etc and for the excellent staff he hires. He's got to where he is for a reason. He's damn good at what he does and he does care for his patients, unlike a lot of others who are just in it for the money. That's not to mention the long hours he works including nights and weekends. So I'm glad he gets paid well for what he does. I'd rather pay a higher price to someone with a good success rate and friendly nature than someone who doesn't care and is just interested in money. There's no need to be spiteful. If he wants to use my money to buy a new car then good for him, he deserves it.
I know there isn't that much feedback about the treatment yet but everything I've found on the net has been positive, whereas with other treatments, there will be cases of it not working or actually making things worse. As I said, I'll do a full report in a couple of months but for now I just encourage anyone who's considering it to go ahead and do it.
I am very happy for you. 🙂
Hi icaretohelp,The doctor from Japan is only partially correct. On one hand it is true that stem cells tend to aggregate around sites of inflammation. This happens when say blood begins to coagulate in and around injured tissue. As it does this it releases specific growth factors that essentially tell the body that this particular site needs repair. That in turn drives a host of primarily immune, secondarily fibroblast and thirdly stem cells to that site. I've detailed the histological mechanisms in the "blood injection" thread I started about a year ago. Anyway, the doctor is not right about stem cells losing their efficacy during culturing. The reason I say this is that they can be suppressed from differentiating into less potent cell types with a number of growth factors, time management methodologies and critical population controls.
Post culturing, the procedure that I've developed involves four primary steps:
1) I perform subcision and needling at the site of each and every acne scar to be treated. This creates macro and micro damage at the deeper dermis and hypodermis levels. Inflammation occurs immediately.
2) Right after step (1) I inject a customized PRP solution that I've discussed before. The platelets aggregate at the site of injection and coagulate in and around the normal blood scaffold that has formed there from the subcision. As previously said, a concentrated number of growth factors is then naturally released by coagulating platelets that trick the body into thinking that there is a relatively serious injury in that particular area. At the same time additional GFs/proteins (artificially added to the PRP solution: TGF-b3, Thymosin-b4, Fetuin-A and Laminin 511) suppress hyper inflammation, which is itself counterproductive. They also help control the stem cell response. Right before injection the PRP is further enhanced by a injectable ECM solution that contains endogeneic ECM particulates.
3) I perform secondary subcision to recreate what I call endo-dermal pockets right through the already apparent haematoma. I then inject the stem cells into this same site. They are immediately guided by GF signalling in the area. Soon after they begin their work as they integrate themselves in the coagulated blood scaffold that is itself reinforced by the said ECM particulates.
4) 6 hours following the 3rd step I have patients undergo their first post treatment LLLT dose. This continues daily in the comforts of their own homes as they have personal LED panels with red and infrared light output. This helps to stimulate the regenerative histological activities post treatment and at the same time further controls the inflammation.
Some liken my technique to absolute overkill. Of course those who say this have never dealt with serious acne scars.
Cheers. Hope this helps u
Hi everyone I am very interested in this procedure and was wondering hat kind of scarring this would be best for.I noticed that there were some pics on the first page and people have had different opinions on whether they were minor of severe. I figured I would instead post pictures of scarring that is similar to mine. They are not what I believe to be severe but they bother me. They are for the most part indentations caused by larger pimples and a few very small pits almost look like enlarges pores. Would this procedure be beneficial?
Pictures of similar Scarring
hi everyone,
just to let you all know i had stem cell treatment from dr khan yesterday and I found him very caring and understanding as is his staff! After the initial fat was taken from my abdomen the cells were cultivated then injected into my open pores and scars, and most areas of my face he also performed subsicion on some of the scars then went over my whole face with a very fine needle I think he was injecting the fat deep into the dermis (maybe!). at this time my face and stomach are swollen and bruised and i have a few blood spots over my face. i have an appointment 7th dec to go back and get skin taken from my neck he is then going to seperate and cultivate the cells to hopefully give me my pigmentation back on my face, i gather he is going to either dermabrase or laser my face before he injects and sprays the cells onto my face to form new skin. I will keep you all posted on my progress. As I have previously stated I found dr khan and his staff the nicest people I have met on my journey to have normal skin
hi everyone,
just to let you all know i had stem cell treatment from dr khan yesterday and I found him very caring and understanding as is his staff! After the initial fat was taken from my abdomen the cells were cultivated then injected into my open pores and scars, and most areas of my face he also performed subsicion on some of the scars then went over my whole face with a very fine needle I think he was injecting the fat deep into the dermis (maybe!). at this time my face and stomach are swollen and bruised and i have a few blood spots over my face. i have an appointment 7th dec to go back and get skin taken from my neck he is then going to seperate and cultivate the cells to hopefully give me my pigmentation back on my face, i gather he is going to either dermabrase or laser my face before he injects and sprays the cells onto my face to form new skin. I will keep you all posted on my progress. As I have previously stated I found dr khan and his staff the nicest people I have met on my journey to have normal skin
BRD,
I have been trying to talk to you many times. Please can you offer me any advice?
I was overfilled with fat graft taken from my innerknee to my lips at age 23.
All the fat seemed to take. My lip is too big,and bulky the fat nodules are peppered all
throughout the lip region including under my nose. I have had several attempts at cutting some of these nodules out..some were removed and some may have grown back??
Do you think the constant trauma of trying to cut them out is causing a reaction
where they could actually be regenerating? I just dont understand why my lip is getting worse
and worse. I am assuming I have alot of stem cells in my lip. Do you know any doctors or any procedures that can help me to reduce all these fat graft nodules? I have heard of
a doctor injecting 5fu to reduce the fibroblasts in the f/g but it seems to me that would be
temporary? Then another uses steroid injections,and yet another lipodissolve.
I am desperate for some help here.
I would also like to know is MRI the only test that would show where exactly the fat grafts are
or is there some easier test like ultrasound?
I feel like its just going to keep getteing bigger and bigger since the effect seems
"cumulitive" please respond to me, or pm me.
I have had these grafts for 16 years now.
Hi everyone I am very interested in this procedure and was wondering hat kind of scarring this would be best for.I noticed that there were some pics on the first page and people have had different opinions on whether they were minor of severe. I figured I would instead post pictures of scarring that is similar to mine. They are not what I believe to be severe but they bother me. They are for the most part indentations caused by larger pimples and a few very small pits almost look like enlarges pores. Would this procedure be beneficial?
Anyone?
Hi everyone I am very interested in this procedure and was wondering hat kind of scarring this would be best for.I noticed that there were some pics on the first page and people have had different opinions on whether they were minor of severe. I figured I would instead post pictures of scarring that is similar to mine. They are not what I believe to be severe but they bother me. They are for the most part indentations caused by larger pimples and a few very small pits almost look like enlarges pores. Would this procedure be beneficial?
Yes, in the hands of a skilled doctor who performs a combination of subcision, PRP and stem cells injections you're scars would significantly improve to the point where they would be unnoticable. You could probably get satisfactory improvement with a simpler procedure, but I'm a firm believer in the "overkill" philosophy.
hi everyone,just to let you all know i had stem cell treatment from dr khan yesterday and I found him very caring and understanding as is his staff! After the initial fat was taken from my abdomen the cells were cultivated then injected into my open pores and scars, and most areas of my face he also performed subsicion on some of the scars then went over my whole face with a very fine needle I think he was injecting the fat deep into the dermis (maybe!). at this time my face and stomach are swollen and bruised and i have a few blood spots over my face. i have an appointment 7th dec to go back and get skin taken from my neck he is then going to seperate and cultivate the cells to hopefully give me my pigmentation back on my face, i gather he is going to either dermabrase or laser my face before he injects and sprays the cells onto my face to form new skin. I will keep you all posted on my progress. As I have previously stated I found dr khan and his staff the nicest people I have met on my journey to have normal skin
That's awesome. I'm glad you're happy. 🙂
BRD,I have been trying to talk to you many times. Please can you offer me any advice?
I was overfilled with fat graft taken from my innerknee to my lips at age 23.
All the fat seemed to take. My lip is too big,and bulky the fat nodules are peppered all
throughout the lip region including under my nose. I have had several attempts at cutting some of these nodules out..some were removed and some may have grown back??
Do you think the constant trauma of trying to cut them out is causing a reaction
where they could actually be regenerating? I just dont understand why my lip is getting worse
and worse. I am assuming I have alot of stem cells in my lip. Do you know any doctors or any procedures that can help me to reduce all these fat graft nodules? I have heard of
a doctor injecting 5fu to reduce the fibroblasts in the f/g but it seems to me that would be
temporary? Then another uses steroid injections,and yet another lipodissolve.
I am desperate for some help here.
I would also like to know is MRI the only test that would show where exactly the fat grafts are
or is there some easier test like ultrasound?
I feel like its just going to keep getteing bigger and bigger since the effect seems
"cumulitive" please respond to me, or pm me.
I have had these grafts for 16 years now.
Hi Jaden,
There are some generic procedures that may work, but they are dangerous and unpredictable to say the least. I may have an idea about to help you, but I have to do some research before I say more. I'll get back to you in a week the latest.
BRD what about my post, did you see it?
LOL, you wrote this as I was replying to your post... Anyway, it may be possible to reduce the fat deposits using an ultrasound massager and/or LED photo-bio-inhibition. I'll have a look at some peer reviewed literature to see if there is any reason to believe that my initial conjectures hold up. Bye for now.
dear all
all this science of stem cell fybroblasts has been around for some time, we have seen isolagen failure, now new product vavelta is available (embryonic stem cells), new products are to become available soon (Juvista for scarless healing after scar revision surgery). i am anyway still not at all convinced that all this would really work on large broad depressions. it will certainly improve skin quality and texture but i am remaining firm believer that scars have to be lifted by filler or implant to be kept lifted. I absolutely love the idea of dermal pocket grafting. your own deepithelised skin graft works as a implant, its autologous very long lasting, it will become if taken part of your own tissue. i am sure it will bring some of fresh fybroblasts in as well as theres some fat tissue left on the acctual graft. unfortunately this seems to be largely overlooked procedure in UK. its available by few docs in states and in Australia,here in UK doctors keep using short acting and altogether unsuitable fat transfer. i think one of reasons is you need dermabrader to take the epithel off before you harvest the graft. dermabrasion has disapeared from UK and Europe and therefore graft cannot be properly prepared. as for the most effective lifting agent i think silicone remains the best in terms of natural looks and longevity, but of course one has to live with synthetic substance in face. i cannot help but hope that some dermatologist here will finally wake up and start utilizing dermal pocket grafting.
dear allall this science of stem cell fybroblasts has been around for some time, we have seen isolagen failure, now new product vavelta is available (embryonic stem cells), new products are to become available soon (Juvista for scarless healing after scar revision surgery). i am anyway still not at all convinced that all this would really work on large broad depressions. it will certainly improve skin quality and texture but i am remaining firm believer that scars have to be lifted by filler or implant to be kept lifted. I absolutely love the idea of dermal pocket grafting. your own deepithelised skin graft works as a implant, its autologous very long lasting, it will become if taken part of your own tissue. i am sure it will bring some of fresh fybroblasts in as well as theres some fat tissue left on the acctual graft. unfortunately this seems to be largely overlooked procedure in UK. its available by few docs in states and in Australia,here in UK doctors keep using short acting and altogether unsuitable fat transfer. i think one of reasons is you need dermabrader to take the epithel off before you harvest the graft. dermabrasion has disapeared from UK and Europe and therefore graft cannot be properly prepared. as for the most effective lifting agent i think silicone remains the best in terms of natural looks and longevity, but of course one has to live with synthetic substance in face. i cannot help but hope that some dermatologist here will finally wake up and start utilizing dermal pocket grafting.
Hi askin77,
First and foremost, welcome to the forum.
I am under the impression that you did not read the entire thread, because you seem to be confusing a few terms that have already been discussed at length. For one, you incorrectly equate fibroblasts and stem cells. You then seem to imply that the methodology discussed here would be ineffectual by tying it to what you perceive as the failures of fibroblast based products, traditional adipose transplantation and standalone PRP. All in all this does suggest a lack of familiarity with this thread's central discussion. Therefore I kindly ask that you read it beginning to end in order to inform yourself about the nature of the topic and relevant details herein.
I will address some of your specific comments below.
askin77: "[...] stem cells fibroblasts have been around for some time [...]"
Response: Technically speaking, fibroblasts are not exactly stem cells. Fibroblasts synthesize connective tissue, glycoproteins, etc (useful for wound healing), but they are generally considered to be near terminally differentiated. Their ability to undergo morphological changes under normal circumstances is very limited. True stem cells on the other hand are much more potent and can rather easily differentiate into fibroblasts and other cell types. That's what makes them effective when they are properly utilized.
Stem cells can be ranked in terms of their potency. Omnipotent stem cells are by far the least differentiated, and therefore the most potent stem cells capable of creating an entire organism. Pluripotent are next in rank, followed by multipotent cell types found in adults. An example of the latter is adipose derived mesenchymal stem cells that are capable of differentiating into cell types found in and around subcutaneous fat. That's why they can be useful when dealing with atrophic acne scars, which are essentially visible on the skin surface due to missing tissue normally found at the dermal and hypodermal levels.
askin77: "I absolutely love the idea of dermal pocket grafting. your own deepithelised skin graft works as a implant, its autologous very long lasting, it will become if taken part of your own tissue."
Response: I also like the idea of dermal grafting. 🙂 When done right it works, just like the methodology I currently employ. When transplanted, adipose derived mesenchymal stem cells can differentiate into various other cell types found at the site of injection/transfer/transplantation. They take their differentiation cues from the surrounding tissue and, in the case of how I use them, from a temporary autologous scaffold composed of blood and extracellular matrix particulates. This, done in combination with an instigated localized inflammation from subcision and needling, can make them rather effective in elevating/flattening skin depressions.
askin77: "[...] doctors keep using short acting and altogether unsuitable fat transfer."
Response: Fat grafting is short lasting only when done improperly. If it is handled incorrectly during the extraction, processing and transfer phases a large a majority of adipose and imbedded stem cells will die, making it next to impossible for most of the transplanted tissue to integrate itself into the transplantation site. Thus the body reabsorbs it over a few months time. On the other hand, when this procedure is done properly, the added tissue can last and even grow for decades to come. Just ask Jaden, who posted about her experience yesterday. (note: I presume Jaden is a female, pardon me if I my presumption is incorrect.) I should also mention that if one can increase the number of stem cells in the transplanted tissue, long term results should be even more apparent. Either way, I only use adipose tissue when I specifically contour the shape of the face and/or fill in large areas of atrophied tissue.
askin77: "as for the most effective lifting agent i think silicone remains the best in terms of natural looks and longevity [...]"
Response: Silicone is in my opinion quite dangerous when used as a lifting agent. One must always face the short, medium or long-term possibility of an immunological reaction to this foreign substance, however "inert" it may be. Localized and systemic effects can never be ruled out. Thus I have stayed away from it.
askin77: "little update on PRP on www.my-cells.net: it will last about 12 months then you need to have top up. for 6. 500 pounds."
Response: We are all at mercy of the natural aging process. Any benefit we get from a procedure will over time be counteracted by the unforgiving winds of time. Nonetheless, PRP in conjunction with subcision, needling and adipose derived mesenchymal stem cells can be an effective weapon in our battles with the realities borne out from our scars, injuries and mortality. The comprehensive procedure I discuss in this forum can benefit us long-term, potentially doing so well into our golden years.
I hope you do not see my reply to your posts as rude and therefore demeaning in any way, form or fashion. I simply want to clarify certain terms and procedures brought up in your original post so that the consequential discussion remain maximally objective.
Once again, welcome to this forum.
BRD
I believe that this procedure can have amazing results but, part of me feels those pics are photoshopped.
BRD or anyone who is familiar with this proceudre have you seen these types of results are those results feasible?
dear allall this science of stem cell fybroblasts has been around for some time, we have seen isolagen failure, now new product vavelta is available (embryonic stem cells), new products are to become available soon (Juvista for scarless healing after scar revision surgery). i am anyway still not at all convinced that all this would really work on large broad depressions. it will certainly improve skin quality and texture but i am remaining firm believer that scars have to be lifted by filler or implant to be kept lifted. I absolutely love the idea of dermal pocket grafting. your own deepithelised skin graft works as a implant, its autologous very long lasting, it will become if taken part of your own tissue. i am sure it will bring some of fresh fybroblasts in as well as theres some fat tissue left on the acctual graft. unfortunately this seems to be largely overlooked procedure in UK. its available by few docs in states and in Australia,here in UK doctors keep using short acting and altogether unsuitable fat transfer. i think one of reasons is you need dermabrader to take the epithel off before you harvest the graft. dermabrasion has disapeared from UK and Europe and therefore graft cannot be properly prepared. as for the most effective lifting agent i think silicone remains the best in terms of natural looks and longevity, but of course one has to live with synthetic substance in face. i cannot help but hope that some dermatologist here will finally wake up and start utilizing dermal pocket grafting.
thank you for warm welcome. i am very happy you have repaired some of my inaccurate descriptions. i was writing that post very fast and i wasnt paying enough attention to the "niceties"in text. i am very well aware of the diference btw adipocyte, fibroblast and stem cell, its anyway my believe that any stem cells we want to inject have to primarily turn into fibroblasts if any collagen production has to be achieved. back to basic as with regards to fat transfer: there are number of renewed dermatologists in united states who consider fat not suitable as such, after you inject it however careful you are fat stars to live its own life in your skin, it can die very fast, it can remain and it can turn bulky big and unsightly.this is very difficult to predict and therefore you never know how you going to end up. there were number of people on different posts with less then satisfactory experience. its my believe that it would have been better to use dermal graft as transporter of either progenitor fibroblasts of stem cells, graft would have filled defect and cells would have effectively improve quality of skin. as for silicone i fully understand your concerns towards safety of this, if you anyway have severe tissue and volume loss and it affects your life to the extend of social suicide, its a good and lasting procedure. there are number of very succesful stories of people who had this done years ago and didnt have any problem at all. at the end of the day is everybodys choice dependent on many factors. thank you in any case for this great post and for all your inteligent comments.
Hi askin77,
First and foremost, welcome to the forum.
I am under the impression that you did not read the entire thread, because you seem to be confusing a few terms that have already been discussed at length. For one, you incorrectly equate fibroblasts and stem cells. You then seem to imply that the methodology discussed here would be ineffectual by tying it to what you perceive as the failures of fibroblast based products, traditional adipose transplantation and standalone PRP. All in all this does suggest a lack of familiarity with this thread's central discussion. Therefore I kindly ask that you read it beginning to end in order to inform yourself about the nature of the topic and relevant details herein.
I will address some of your specific comments below.
askin77: "[...] stem cells fibroblasts have been around for some time [...]"
Response: Technically speaking, fibroblasts are not exactly stem cells. Fibroblasts synthesize connective tissue, glycoproteins, etc (useful for wound healing), but they are generally considered to be near terminally differentiated. Their ability to undergo morphological changes under normal circumstances is very limited. True stem cells on the other hand are much more potent and can rather easily differentiate into fibroblasts and other cell types. That's what makes them effective when they are properly utilized.
Stem cells can be ranked in terms of their potency. Omnipotent stem cells are by far the least differentiated, and therefore the most potent stem cells capable of creating an entire organism. Pluripotent are next in rank, followed by multipotent cell types found in adults. An example of the latter is adipose derived mesenchymal stem cells that are capable of differentiating into cell types found in and around subcutaneous fat. That's why they can be useful when dealing with atrophic acne scars, which are essentially visible on the skin surface due to missing tissue normally found at the dermal and hypodermal levels.
askin77: "I absolutely love the idea of dermal pocket grafting. your own deepithelised skin graft works as a implant, its autologous very long lasting, it will become if taken part of your own tissue."
Response: I also like the idea of dermal grafting. 🙂 When done right it works, just like the methodology I currently employ. When transplanted, adipose derived mesenchymal stem cells can differentiate into various other cell types found at the site of injection/transfer/transplantation. They take their differentiation cues from the surrounding tissue and, in the case of how I use them, from a temporary autologous scaffold composed of blood and extracellular matrix particulates. This, done in combination with an instigated localized inflammation from subcision and needling, can make them rather effective in elevating/flattening skin depressions.
askin77: "[...] doctors keep using short acting and altogether unsuitable fat transfer."
Response: Fat grafting is short lasting only when done improperly. If it is handled incorrectly during the extraction, processing and transfer phases a large a majority of adipose and imbedded stem cells will die, making it next to impossible for most of the transplanted tissue to integrate itself into the transplantation site. Thus the body reabsorbs it over a few months time. On the other hand, when this procedure is done properly, the added tissue can last and even grow for decades to come. Just ask Jaden, who posted about her experience yesterday. (note: I presume Jaden is a female, pardon me if I my presumption is incorrect.) I should also mention that if one can increase the number of stem cells in the transplanted tissue, long term results should be even more apparent. Either way, I only use adipose tissue when I specifically contour the shape of the face and/or fill in large areas of atrophied tissue.
askin77: "as for the most effective lifting agent i think silicone remains the best in terms of natural looks and longevity [...]"
Response: Silicone is in my opinion quite dangerous when used as a lifting agent. One must always face the short, medium or long-term possibility of an immunological reaction to this foreign substance, however "inert" it may be. Localized and systemic effects can never be ruled out. Thus I have stayed away from it.
askin77: "little update on PRP on www.my-cells.net: it will last about 12 months then you need to have top up. for 6. 500 pounds."
Response: We are all at mercy of the natural aging process. Any benefit we get from a procedure will over time be counteracted by the unforgiving winds of time. Nonetheless, PRP in conjunction with subcision, needling and adipose derived mesenchymal stem cells can be an effective weapon in our battles with the realities borne out from our scars, injuries and mortality. The comprehensive procedure I discuss in this forum can benefit us long-term, potentially doing so well into our golden years.
I hope you do not see my reply to your posts as rude and therefore demeaning in any way, form or fashion. I simply want to clarify certain terms and procedures brought up in your original post so that the consequential discussion remain maximally objective.
Once again, welcome to this forum.
BRD
i seem to lost my replay so i try again. i am very grateful for warm welcome and sorry for not to be accurate in all the terms. i was writing this very fast and didnt have that much time for all the "niceties" in text. i do acctualy know the difference btw adipocyte, fibroblast and stem cell. its my believe that your stem cells have to primarily turn into fibroblasts if you want any colagen production.anyway back to topic: as for fat transfer number of renewed dermatologists dont recommend this for acne scars simply because the implanted fat starts to very quickly live its own life, it could die or it could live and turn bulky and lumpy no matter how careful you inject it. there were number of people on different posts with less than satisfactory results. in my opinion dermal graft would have been better as a transporter for progenitor fibroblasts or any form of stem cells. graft would have lifted scar and cells improved skin quality. as for silicone i fully understand your concern but, if you have severe scars which affect your life to the point of social suicide all you want is lasting proven and if done carefully safe treatment, thats precisely what silicone is all about. theres special tread here dedicated to this treatment and let me tell you the results are remarkable at least to say. its all about prefferences and needs of different people. i more than anybody else wish for safe autologous and slowly progressive treatment to become reality but unfortunately we are still very far from it right now. future is bright. thank you for this great tread and for all your inteligent comments
askin77 said:little update on PRP on [Removed]: it will last about 12 months then you need to have top up. for 6. 500 pounds. :rolleyes:it brings me back to one and only thing dermal grafting. datura had one round i think, wonder how well it worked...
Does that mean that the procedure ,performed by Dr Khan ,only will last for 12 months? That would be terrible.
