Oral Antibiotic
Reviews
3.4
1734 Reviews
Oral Antibiotic
Efficacy
56%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Should never be used on its own and for a maximum of 3 months.
Oral Antibiotic
Side Effects
Medium-High
Oral Antibiotic
Acne.org’s Real World Take
Antibiotics should be used for a maximum of 3 months, provide only moderate benefit and only to some people, and may lead to side effects and strains of resistant bacteria. Studies do show doxycycline can reduce severe acne in the short term, and as far as oral antibiotics are concerned, it’s usually the go-to, but approach with caution and stay your own advocate.
Oral Antibiotic
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Doxycycline
Compare To Other Treatments
5
20.7%
4
32.9%
3
22.1%
2
12.7%
1
11.5%

Used Doxycycline? Rate It:

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February 21, 2007

Pros:

moderate acne, doxy maybe dropped it down to mild

Cons:

stop taking it and acne comes right back

doesnt work well enough to try. Once you stop, be prepared for an even worse face.
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October 26, 2006

Pros:

I've been taking it for two and a half months and I notice that I don't get any deep deep zits anymore.

I'm writing this from a mental point of view. I can't believe I am even bringing my fingers to this keyboard to write something on an ACNE site. I've never had mild acne until this summer when it hit me like a ton of bricks. A ton of big, fat, scabby, zitty, bricks. Its only a zit! But it wasn't A zit...I dont smother my face in the pillow and spend my whole summer alone in a bed because of A zit. Go outside and have fun! But you can't have fun when you can't be in control of how you look. I must admit, I still don't have it as bad as other people... but the breakouts that I use to have once or twice a year come to me every week now. I really want to find hope in this medicine. Not to sound ignorant but if we can do amazing things like brain surgery or gastric bypass (spelling?) we should be able to find one pill that helps us. I'm sick of having false hope's and up's and down's. I just hope I can look back on this and laugh or say "Thank God Its over" ya know?!
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April 17, 2018
Hesitated to do prescription and regretted it the entire time I was on it
Where to begin? I took this because nothing else topically worked and at 25 my acne was the worst it ever had been. I was super ashamed to show my skin and my boyfriend even told me that he thought my self confidence was affecting our relationship. So even though I have always been against using drugs for my skin, I just try to avoid prescriptions at all costs generally, I went to the dermatologist and asked for anything other than accutane because I had just heard so many bad things. Short story - I was on it for 4 months, noticed some decrease in the longevity of my pimples decreased somewhat, at least the white heads. My cystic pimples I noticed no change at all and the same for the blackheads that plague my nose and temple. On top of this, my stomach for the first time became a mess. I actually lost 15 lbs while on doxy because I was always so nauseated, I guess that was a nice side effect. But it really was a horrible experience. Once I stopped, my stomach got better almost instantly. My decrease in whiteheads also stopped pretty instantly once I stopped it. They came back within 1 week. My boyfriend's sister told me months ago about a brand she likes called Ninja. I thought it sounded like a silly name and never did anything to follow up. But when I was desperate, I gave them a call and was so surprised to actually get someone on the line and that someone was the owner! She took about 1 hour to talk to me about my skin, gave me a list of products she would recommend for me and asked me to check in if I decided to give them a shot. Best thing I ever did. Within 2 weeks of using the products, I saw more results than I have ever seen from any other treatment and I promise you, I have tried nearly everything. Now 9 weeks in, I am completely clear of cysts (except for one stubborn one on my neck that I have had for 3 months), zero whiteheads and best thing is that once I pulled the existing blackheads, no more have formed. I am totally in shock. My mom, boyfriend and little sister have all commented on my positive attitude and how much happier I seem in general. I guess I had not really realized how much acne had affected me on a deeper level but now that my skin is clear, I feel lighter, happier. And I just keep going back to my original thought that no one should do drugs for acne.
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October 25, 2017
Results don't last
So because this kills the bacteria in your face, the acne does get better. Unfortunately you can't stay on it forever, so once you stop, the acne comes back. At least that's what happened for me! It works, but the results don't last. Also, antibiotics also kill a lot of good bacteria in your gut which may cause long term digestive issues. All in all, not worth it.
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April 24, 2018
Have you had any luck since your course of Doxy? I've been in the same position as you and have finally put my acne cause down to Leaky Gut made worse by Doxy.
October 7, 2017
Temporary fix
This worked well but acne returned as soon as pills stopped. You cannot stay on antibiotics long term as it destroys all the good gut flora and can lead to antibiotic resistance.
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October 30, 2017
Mine came back too after I was off it
September 21, 2017
useless
i have mild-moderate acne, mostly cysts & nodules. i was prescribed with doxycycline, 50mg once a day. i was on it for 2-3 months and it did nothing for my skin. it took out 5 smaller pimples minimum but did nothing for larger ones. i got off the pill and my skin was okay for a while but (like i read in some reviews) it was as if my skin got very angry with me & my skin worsened a tenfold. if i tried 100mg a day maybe i would have different results but i think that is highly unlikely, considering it did almost nothing whatsoever at 50mg. 10 less pimples perhaps? there was minimal effect plus the bad chemicals were not worth it. i truly believe that this is a temporary fix (if it even works) and you should rule it out. there are much better treatments that will give you good results, topical or oral. i tried this without doing research on it because my doctor recommended it to me, which was not a wise idea on my part. you know your skin best. if i had seen these reviews on here, i would not have risked taking the pill.
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November 10, 2017
Hey! This happened to two of my friends who had moderate/severe acne that was mainly cysts and nodules! They were then prescribed roaccutane and haven't had a cyst ever since so that might be the case for you (:
June 28, 2017
Worst idea for my skin!
After fighting a skin discolouration on my trunk (stomach and back) and being misdiagnosed all my life I finally discovered what is was - a bacteria that killed the pigmentation in my skin. i was put on doxycycline for 2 months along with light treatment to even out the pigmentation. i was fine and perfect after the 2 months - it was actually the first time i've seen my trunk without discolouration as long as i can remember (I'm 29 now). however, my doctor put me on doxy for an additional month, so in total i was on it for 3 months. my face all my life was perfect - never had acne, i would prob have 5 pimples a year and prob bc of that time of the month. I was also on the ZO Skin Medical Care line - a top skin care line from Dr. Zein Obagi. However, i noticed that while i was on the doxy i would get some bumps on my face and light break outs but it wasn't bad and i thought the ZO line was just purging my skin. However, after 4 months on the ZO line your skin is supposed to be flawless so I ruled this out (as my 4 months on ZO was gone but i was on doxy for about 3 months at this point). After my third and final month of doxy - the week i came off my face blew up with inflamed cystic acne like i've never seen before. Now to be in your late 20's with this after never having acne was my worst nightmare. i was literally going crazy and going into a depression - here i was - someone who always got complimented on my skin now having painful cystic acne at 29. i didn't go into the office, i even felt ashamed for my family to see me. i know this sounds shallow but it was a lot to deal with bc it was so sudden and severe. Doxy fixed one problem (the discolouration caused by bacteria on my trunk area) but caused another. tbh had i known this would happen i would prob choose to live with the discolouration. Luckily my derm is amazing and world renowned- she is trained by Dr. Obagi himself - I'm now on my second month of roaccutane because of this anti biotic and on the ZO line for acne treatment now. i always get weekly extractions and kenalog injections as my skin is still transitioning. there's a major improvement. my first week on roaccutane just purged everything out and my derm also put me on steroid tablets and another anti-b for a week to reduce any inflammation which worked like a charm. after a month of my acne being cystic they finally started to form white heads. also now everything has completely flatten - I'm on day 45 (approx) of the roaccutane. i get the one pesky pimple some days but they quickly turn to a whitehead. But i have alottttt of scarring from my blow up episode post doxy that I'm currently peeling away with the ZO products. its taking a while and I'm being so impatient as i just want to be back to normal again. My derm says i have about a month again - fingers crossed i get back to having clear skin as i have to wear make up to hide my scarring. Please anyone using or about to use doxy- be careful - it was the worst decision I've ever made for my skin! I've been in hiding for 2 months now and well I'm getting better i'm now getting out and being social again (with loads of make up to hide my scars).
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January 4, 2017
not working, yet
I've been on it for about 2months, I don't know if it's psychic but I don't think this is working for my inflammatory acne. if anything, it only made my acne break out the week 2 and 3 of taking it. Thanks to it I have lots more scars to get rid of. My Dr said as there are non-real improvements by now, I will have to take it for more than 3 months. Maybe it gets worse before it gets better. will update later!
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March 18, 2017
This is exactly the same as me, I've been on doxycycline for 2 months now and it hasn't changed my skin, if anything made it worse. I mainly was breaking out in the 2nd and 3rd week also. And yes I never use to scar even though I would always squeeze a pimple when I got one, scarring was just so rare for me. But now every pimple I get scars. But I'm just going to wait it out and hope it eventually gets better
December 19, 2017
Howd it go?
August 19, 2016
Not for me, but maybe worth a shot
I was prescribed this after I had a very bad experience with Minocycline (headaches, and possibly pseudotumor cerebri). I got headaches right off. I tried it for a couple of days, but it still was giving me head pain. I don't know if I'm just not meant to take antibiotics (I've heard doxycycline is related to minocycline) or what, but after what happened with the minocycline I wasn't willing to risk staying on a whole week. It didn't work for me, but that doesn't necessarily mean it won't work for you.
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August 22, 2016
Did you find anything that worked for you? I have peri oral dermatitis and I have to take either minocycline or doxycycline...... I CANNOT tolerate Minocycline and Doxycycline is tolerable but I feel so strange on ti and I don't like it.
June 30, 2016
Didn't work too well
Unfortunately, doxy didn't work too well for me. I was using Dan's BP nightly before I went on doxy (had been on BP for about a year), and still had about 5-10 painful pustules on my face at any given time. I wanted to have something fighting the bacteria from the inside, so my GP put me on 100mg doxy / day. It took a while to notice any kind of difference, but about a month and a half later I noticed that I would only get 1-2 pustules on my face at any given time (along with some small comedonal stuff). I got excited that it was finally working, and for about a month I didn't worry about my face too much. Unfortunately, about 4 months after I started, my acne came back worse. My whole face started breaking out - not in cysts, fortunately, but in small, raised ones with white heads. I had about 30 of them towards the tail end of my doxy treatment. I also developed eczema / dermatitis around my T-zone, near my temples and under my chin. I realized that the doxy was doing more harm than good at this point, so I quit cold turkey. My eczema disappeared within a couple days, and most of my acne was gone within a week. I went back to having 5-10 pustules on my face, but it was better than where doxy got me. Basically, like with all antibiotics - this really is not a long-term fix.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.