I am on Adoxa 75 mg twice a day. I've been on it for almost a month, and seen absolutely no improvement. If anything, my acne has spread to new locations on my cheeks and forehead. At first, there was a very small reduce in the redness, but quickly after it fired up again. On a scale of 1-10 (1 being perfect skin), I'm at about a 6.

I will stick to topical solutions, ie: benzoyl peroxide.

Ive been on doxy for 2 months, its the only thing out there that did anything, take it after your biggest meal, i was supposed to continue with like 6 creams, but after years and years of searching, im so sick of creams they havnt been doing anything, so i have been pretty much leaving it up to doxy now that my face isnt so gut wrenching to look at, still wash face everyday, creams might make it work quicker, i cant believe i wasted a year and hundreds of dollars trying to find a cream, i didnt think a pill would work, so if u get anything i recomend this one.!

I've tried dozens of acne products for almost 10 years now (23 yr old female now, all topical medications). from benzyl peroxide, tactuo, spectro, cerave, clindoxyl and even natural things like tea tree oil and witch hazel, and NOTHING worked. All they did was dry out my face and make my acne flare up (not to mention most of them had a less than pleasent scent). My doctor prescriped doxycycline since I was fed up with topical agents, rather than going straight to accutane (which i'm very hesistant about considering the long list of side effects). I'm about halfway through my 90-day prescreption of doxycycline. It didn't do anything for the first month or so, but after the halfway mark, I've noticed that a lot of my larger pimples have dissappeared, and I haven't gotten any of the bigger pimples since about day 30. I still have a lot of the smaller ones that for some ironic reason are a lot more stubborn than the bigger ones, but I can at least easily cover those up with some concealer. Although it's taking a little longer than I had hoped, I'm pretty happy with the results. I still use my tea tree oil cleanser, exfoliator and clay mask (all from the body shop) along with Cerave and Spectro, but only because I don't want all these products to go to waste. My doctor also recommended that I stick with cleansers while on doxy for maximum effect. Even though doxy isn't as fast as accutane might be, I haven't seen any bad side effects (the best of which being NO dry skin! Something I had to CONSTANTLY deal with when on topical medications). Others have said that taking it on an empty stomach gave them really bad nausea but I've only had that happen to me once. I try to take it on an empty stomach since that's how it'll best get absorbed into the body. Make sure you don't take any dairy a few hours before or after either!! But you need to replenish the good bacteria it kills, so I try to eat yogurt earlier in the day with probiotics... apparently doxy will lose its effect if you don't replenish the good bacteria killed. don't forget though that yogurt can cause acne too so tread carefully. Anyways, I guess I'll see how my face will turn out come the 90 day mark (about 45 days in now). If any changes happen, I'll try to update it here.

I took 100mg daily and had clear skin for 6 months. Cleared up my acne within a fortnight. It was amazing. No real side effects unless I took one on an empty stomach - awful nausea would follow. So I only made that mistake a couple of times. Really good treatment but I found they stopped working after 6 months so then it was back to the drawing board...

I have been on this prescription medicine and Retin-A cream for about 7 weeks. The first 6 weeks were tough for me. I definitely went through the "purging" stage and experienced some bad break outs. Once i reached this week, week 7, i can see a HUGE difference in my skin. My acne is mostly small to medium sized white heads on my forehead and around my mouth/chin. This week my entire chin is cleared up along with my forehead being clear but also with a few minimal pimples near my mouth which are hardly noticeable. The only thing that bothers me is the redness and hyper pigmentation that is left behind after each breakout that you get. This is most likely due to the cream i put on overnight because the cream, Retin-A, works with the surface of the skin while doxycycline works with your body internally. Overall i would definitely recommend waiting out on this product even though it may take a few weeks for it to kick in. Seeing this progress with my skin is super encouraging and i can't wait to see what it looks like when it clears completely and all the redness fades. Don't lose faith on this medicine!! Wait it out before giving up too soon.

I have taken doxy for a year now, it did improve the first couple of months, settled my skin but never completely cleared it and i got bad hormonal break outs on my cheeks, jaw line and chin. I combined it with the Epiduo cream which was ok but i feel the retinA cream from iherb tropical cream worked far better along with a fragrance free sensitive skin facial wash the cetaphil is a good brand. I tried dermal rolling and that was ok also but only helped temporarily same with laser treatment. I'm currently on the pill and I'm having good results so far as it is stabling my hormones i feel... but i think in the end I'm going to have to try accutane unfortunately and i wish i had gone on it sooner because everything else seems to be failing and not permanent results like what i hear about accutane. Hope this helps. so in my opinion doxy didn't make it worse, it just settles it and makes it not as bad as what it would have been. I'm 21 years old and had acne since i was 18 it also runs in my family. big cystic acne :(

I began to use Doxy for about two months along with RetinA with no reaction. The Doxycycline did not seem to be affecting my skin as much as the retinol and my dermatologist suggested I go off the Doxy and switch to just RetinA, no oral medication. After my acne seemed to not be improving she advised me to go back on. After about a week I began to become extremely allergic to the sun despite applying sunscreen constantly throughout the day. I developed horrible hives that blistered all along my right hand and arm as well as a little on my left. They were itchy and burned, making it very difficult to concentrate in school. In addition, my face became very red and irritated. This along with my hand took weeks and weeks to finally heal up. Doxy did not work for me, and during my second round with Doxycycline, my acne was not improving.

I had a horrible break out. It lasted 3 months. Just when things were looking up I had an allergic reaction and had to take prednisone. 2 weeks later I was living in hell, twice as bad. The doxy cleared me up in 2 months. Problem is, I lost 25 lbs while I was on it. Couldn't eat dairy products. And your body will get used to it after awhile. It works great but with a price.

Took this from 2010-2012 and again for 2 months this year. The first time I had no side effects and it did seem to help a bit, but it was in conjunction with Duac and Yasmin, so I don't know how much it really helped. This time around, having had no sun sensitivity last time, I popped a pill and some advil for a headache then walked my dog at the park--big mistake! Apparently mixing ibuprofen and doxy exponentially increases your chance of a reaction to the sun. My arms and feet felt intensely prickly, and almost like something cold and wet was on them, then broke out in a rash that stayed till a few days after I stopped the medicine. Still, an okay thing to try short term.