Topical Retinoid
Acne.org’s Real World Take
May provide partial relief at higher prescription dosages. Comes with less side effects than the other two topical retinoids, tretinoin and tazarotene, but may also work ever-so-slightly less well. No retinoid is likely to be a game changer, but studies do show a partial reduction in acne.
Topical Retinoid
How to Get It
Adapalene is available in strengths up to 0.3% by prescription. Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one. Adapalene is also available over-the-counter in 0.1% strength. Here are some places you can find it online.
Used Adapalene? Rate It:
Choose from 1 to 5 stars
February 14, 2023
May not help severe acne
As everyone says, you might experience purging, irritation and dryness when starting this treatment before you see any improvements.
For me it took a couple months and a reduction in how much i would apply to see the results, however i would say this treatment is not greatly effective with more severe acne as although it helped with the mild texture on my forehead it wasn’t effective with the more severe acne on my cheeks rather just leaving my skin red and de-hydrated.
January 21, 2018
Not worth it
Works good by increasing skin turnover but has far more sideeffects rather than benefits. Still recovering from redness and bad texture of skin.
September 14, 2017
Scary
I've never had sever acne ( I am 20 year old male)..I do get pimples but not the huge ones ...I tried Adapalene (Differin) and after 4 days I got 4 huge breakouts(Big,Red,) ..The initial breakout is just too scary for me..I stopped it...I'd recommend to use azelaic acid gel or Cream for acne ...It's Far More Effective and It also Cures Pigmentation and scars (It blocks melanin) ...Just research about azelaic acid for acne..Far more Better than Benzoyl peroxide ..
June 10, 2016
Don't know what to think
OK so I started using this in conjunction with Zineryt after Retin A seemingly stopped working.
I am currently 1.5 weeks into treatment (which as I know from former experience with a retinoid is very little time) However I am having the worst breakout ever, even worse than when I had the initial breakout from Retin A. My left cheek is covered in huge red spots and now my forehead is also starting to act up. My social life is taking a hit as I feel reluctant to leave the house looking like the mess I am right now. I'm really having my doubts about this. However I will keep using this as they say it takes a month to see some results. I'll update when I reach the one month mark.
May 15, 2016
no
Was not satisfied at all. it is too irritating to me and no improvement
ScrawnyMints
June 9, 2017
Why the two stars then?
May 11, 2016
Wasnt great
I have oily skin and started this about 3 months ago. It had a very bad effect on my cupids bow area and around my nose as it was very dry and itchy. I didnt see a huge difference in my acne either. Wouldn't recommend
January 8, 2016
3 months nothing happened
I started using differin on the first of October, so the first two months were so bad! I was breaking out like crazy all over my face. But after i saw some reviews i decided to continue using it. Which didnt work at all. And i want to know should i continue using it or no?
P.S I've used bp retin A and many more.
April 21, 2015
Huge let down
I have been on Differin .03% for four months and 2 days and today I am experiencing one of the worst breakouts to date. I had seen improvement but nothing consistent. Looking at my face today, one would never guess I was taking care of my skin. My entire right side mouth/jaw/chin area has several inflamed pus filled acne that is hard to the touch. It looks disgusting. I choose not to wear makeup so everything is out there for the world to see. I usually go through a breakout and then a clear up cycle but I can't foresee this getting any better. The pros I suppose is that Differin is the gentlest retinoid of the lot and will last you forever. I recommend people give it 3-6 months before throwing in the towel just so that they can mark it off their list if it doesn't work. I am going to stick it out until the 6 month mark and will update if my review changes. Hopefully this will not discourage anyone from trying this as different people react differently to different retinoids.
August 5, 2015
Did your doctor prescribe other medication to go with this? Mine gave me doxy for 2 months and then we began a regiment with Differin and Benzaclin (to kill the bacteria quickly).
January 9, 2015
Might work for you, but not for me.
Okay, I had clear skin for a very long time and then I started breaking out, very mild acne. Like any teenage girl, it bothered me. I went to my doctor and she prescribed me Differin. I have been on it now for 7 weeks. My skin is horrible, I am embarrassed to go out with my friends anymore because of how horrible my skin is. I know have cystic acne on my cheek (where I have never broken out, EVER) . My face is very irritated, dry and red. This has not helped my face, instead it has caused me to go a complete 180 turn for the worse. This product did not work for me!
August 16, 2014
Not sure
I'm 24 have had acne on and off since a teenager trying lots of different creams anti-biotics... Last years before Christmas I had an extremely bad break out of acne over my face, chest and back after trying a a couple of different treatments eventually i found the antibiotic Oxytetracyline after about 3 months if being on it my skin cleared I am still carrying it on in fear it will come back. In this time I went to a dermatologist and this is when she recommended differin adapaline to carry on long time during and after my antibiotic course. The problem is I have tried a couple of times to start this product out the longest I have lasted is about a week as my skin seemed to get flaky and try break out even more... Is it worth me sticking it out through this. Also I do used sun beds every other week or so and I will struggle to give this up, help?