Adapalene / Benzoyl Peroxide (Epiduo®)
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Side Effects

Usually known by its brand name Epidu®, this topical treatment is a combination of adapalene, which is a type of medication called a...

Usually known by its brand name Epidu®, this topical treatment is a combination of adapalene, which is a type of medication called a retinoid that reduces inflammation in the skin and helps promote skin cell turnover, along with benzoyl peroxide, which kills acne bacteria and dries/peels the skin. 

It is usually applied once a day before going to bed.

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3.7
496
Read All About Adapalene / Benzoyl Peroxide (Epiduo®)
Compare To Other Treatments
5
39.1%
4
29.2%
3
10.3%
2
7.9%
1
13.5%

Used Adapalene / Benzoyl Peroxide (Epiduo®)? Rate It:

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November 5, 2012

Pros:

Clears up spots
Helped heal a small cyst within a couple days
Doesn't burn or make me peel

Cons:

It makes me flake a little- which I don't really mind much

I got a bag of samples from my dermatologist. So far its working great. I just rub it in to my areas with acne at night and then the pimples slowly fade within the next couple days. I use a really good moisturizer recommended by my dermatologist that prevents the dryness of Epiduo. CeraVe Moisturizing Cream...it's great.
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October 27, 2012

Pros:

This product works great. I was starting to think there was no way to clear my skin but the my doctor suggested this topical cream. It starts to work within a week and by 2 weeks my skin was completely clear with just a couple acne scars left.

Cons:

There is no downside to this topical acne treatment except that it makes your face incredibly dry, which can be treating with a tiny bit of moisturizer. Also the price of the cream is really expensive

I would recommend this product to anyone. After years of suffering acne I finally found a product that has cleared up my skin. Even though the price is quite high here in Canada it is defiantly worth the results.
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September 29, 2012

Pros:

-Can be used as Treatment on the regiman

Cons:

-Expensive for the amount that you get

I didn't have health insurance when I got Epiduo from my dermatologist and paid double what I probably could have. I used a tiny pea size for a few months for moderate results. When I started the Regiman, I used the Epiduo I already had as my BZ product, and it completely cleared up my acne! However, I made the mistake of ramping up to the full amount in a week (because I'd already been using BZ for a few months, so my skin is used to it, right?) WRONG. DON'T DO THIS. If you've never had a chemical burn, this is not the way to find out what it feels like! Be careful when increasing dosage of BZ, even if you've been using a tiny bit for a long time - this stuff is powerful and it will feel incredibly unpleasant. Be patient, I promise you the results are worth it. But with that said, Dan's product is just as good, for much less money.
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September 23, 2012

Pros:

Within the first few weeks it did clear my acne, then it all changed --- look at the con's....

Cons:

- Dried up skin so bad
- Burned my skin for the first few weeks
- soar-ness of skin and burning sensation.
- Made my acne 10 times worse!...
- not worth it!.

I went to my GP about my acne, i was getting down about having 10 spots roughly.. I was prescribed this treatment i regret the day i purchased this. The first couple of weeks i did see a massive improvement then the 2 week in initial break out occurred and i thought ok..fine!...then i thought it would go away and it did sort of but then 4 weeks in i went from 10acne spots roughly to 40!...left me with horrific scarring and my skin has been thinned out so much. I went back to my gp and she told me to use it still so i did for another 4 weeks and each morning i would wake up to another new spot that would only add to the scars. To me this product is not worth it anymore, it might be great for others but for my skin is was not... it made my acne 10 times worse then before, left with scarring and little open pores on my cheeks. I use this product only once a day and within 2 months my skin feels destroyed.
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September 23, 2012

Pros:

Gets rid of spots
You can feel it working

Cons:

Skin Peeling
Slight Burning

Basically, I've been struggling with light acne since I was about 15. I'm 19 now and for the first time in those 4 years, my doctor prescribed Epiduo for me. I read a lot of reviews and was apprehensive about using it. I used it initially and it was burning my skin, so I stopped. However, I restarted using it and my skin cleared up within a week. Not entirely cleared, but only a few minor, tiny spots remained. It made my skin feel a lot more smooth. It burns a little when you put it on, but you can feel it working on your skin and that's a real plus for me.
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September 14, 2012

Pros:

Cleared up skin

Cons:

Was a little drying

This is one of the best products out there its the only thing that cleared up my skin and I have very hard to get rid of acne.
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September 9, 2012

Pros:

No redness
No peeling

Cons:

Oily skin
Breakouts worse

I had success with Benzaclin for about 7 years. When I was 22, I started noticing "bumps" under the skin on my cheeks. No amount of exfoliating I did could get rid of them. I went to the dermatologist. She prescribed me Epiduo. I was happy with this choice, as I new I needed a retinoid to solve my skin issues. The first 2 months my skin broke out pretty horribly. Like, worse than I've ever seen. But I research everything and was well aware that this was going to happen initially. Well, I've now been on Epiduo for 5 months. The "initial breakout" never stopped. My skin is bumpy all over, oily (my skin is usually dry), and a complete mess. It NEVER looked this bad before using Epiduo. I know Epiduo helps some people. I have friends with beautiful skin because of it. However, Epiduo is not for everyone. I hate that I have used this for so long, as I know it's going to take a long time to repair the damage that has been done.
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September 5, 2012

Pros:

Gets rid of acne!
Use one time a day, huge time saver

Cons:

Redness
Burning
Drying
Peeling
Takes a bit of time

Epiduo works very well. I have been suffering from acne for 2 years. It was only on my forehead, but when it started showing up on my cheeks is when I went to the doctor for Epiduo. I have tried EVERY product for my acne. NOTHING worked except for Epiduo. The acne on my forehead cleared completely in under a week, my cheeks however have not cleared completely. I do however see massive improvements in it. When I first started using it, it burned and itched horribly. After a bout a week the burning stopped, but it stills leaves my face a little dry. But it has worked for me better than anything else, and I would recommend it to everyone!
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September 4, 2012

Pros:

Exfoliates your skin as all the dead skin falls off
Clears acne up

Cons:

Intense drying and flaking
Burns and stings when you put it on
Face gets real dry to the point when it hurts to smile sometimes

I havent been using epiduo very long but i can tell that its working. Besides the dryness the acne does clear up and it will burn and sting but you just gotta take the pain! Good luck to everyone out there fighting with their acne problems :)
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September 1, 2012

Pros:

light, clear, not that expensive

Cons:

has not cleared my acne

I use a gentle wash, and light moisturizer afterward every day before going to sleep. It doesn't work for me.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.
Find a Doctor Using The American Acacemy of Dermatology Website

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.
Find a Doctor Using the American Society of Plastic Surgeons Website