Topical Retinoid / Topical Antibacterial
Reviews
3.7
579 Reviews
Topical Retinoid / Topical Antibacterial
Efficacy
67%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid / Topical Antibacterial
Side Effects
Low-Medium
Topical Retinoid / Topical Antibacterial
Acne.org’s Real World Take
A way of using benzoyl peroxide in combination with the topical retinoid, adapalene, that studies show works a bit better than benzoyl peroxide alone. Comes with side effects for the first weeks and can bleach fabric. Note: When used correctly, benzoyl peroxide on its own can completely clear the skin.
Topical Retinoid / Topical Antibacterial
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Adapalene / Benzoyl Peroxide (Epiduo®)
Compare To Other Treatments
5
38.2%
4
27.3%
3
11.1%
2
8.6%
1
14.9%

Used Adapalene / Benzoyl Peroxide (Epiduo®)? Rate It:

Choose from 1 to 5 stars
February 7, 2015
Finally!!! :)
Hi. I was struggling with getting cystic pimples nonstop (especially in my chin area) for past two years. I tried to eat healthier, cut out dairy for a period of time, sugar, got my hormones tested... anything I read online I tried to no avail. I was getting very frustrated and somedays I wouldn't leave my house to see my parents because of the state of my face. It really lowered my self esteem. Went to doctor and he thought I had peri oral dermatitis so he put me on deoxycycline. No change. He then put me on tactuo. Wow! After two month my face is now always clear. I don't want to jinx it but I love this. I only use once a week now. I get compliments and I love my skin (haven't said that in awhile)! Be careful not to put too much on, you will look windburned and skin will peel like crazy. After awhile, doesn't burn anymore :)
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January 21, 2015
Wow.
Okay, so I've been struggling with acne for 7 years. Technically 9 years, but that doesnt matter. I tried everything. I learned my skin was allergic to salicylic acid which stinks because a lot of treatments use it. My skin would be so oily because it made my skin so dry... I bought expensive treatments, I bought cheap treatments, AND I used natural alternatives. (I always start with natural because I hate western medicine) Nothing ever worked. I changed my eating habits, my sleeping patterns, everything you would read in a magazine and a book... I swear I tried everything. Sometimes it would work for a week then get really bad. I went to the dermatologist once and it never helped, so I refused to go and just tried to live with it, which was a bad idea because my face was covered with bumps and scars and blackheads. So so so embarrassing, especially surrounded by people who have actual flawless skin. The pressure is so high these days, so one thing I learned is thag you can't ever judge a person on the outside because they usually can't help it! Anyways- My mom took my sister to the dermatologist because her acne was pretty bad as well. I refused to go, but my mom told the doctor about me and he prescribed my sister EpiDuo. He said I could just it if I wanted to. Knowing stubborn old me, I didn't want to use it. Weeks passed, and my sister' skin started to clear up. She just did the instructions and her skin was flawless. I was so jealous. And of course, my mom bugged me everyday how I should use it. So one night, I was so tired if my embarrassing acne that I had everywhere and I had been dealing with it for SO long, that I gave in. I used it. And I washed my face with Cetaphil every morning and night and applied EpiDuo every night. I think I started in November. I also stopped wearing makeup, because I'm a ballet dancer and I have no need to wear it because it just settles in my pores... SO, I've used it basically every single day and it's January now, and my skin is changed! It's BEAUTIFUL. It started out very dry- My skin is very sensitive. I think my acne made it even more sensitive. It was never "worse before it gets better" (which is strange because that's how I always was) Also, DO NOT APPLY AT THE BEACH BECAUSE YOUR SKIN IS ASKING FOR A BURN. I applied it at the beach, only once, at night, and the next day my skin fried. It was awful. I couldn't even make facial expressions because it was so sore. I learned to use a lighter cleanser (Cetaphil) and moisturize with the Heavy Cetaphil moustrizer. Now, my skin is clear and I can run my hand over my forehead and not feel bumps! I haven't had that in such a long time. It's also not as oily which is rare for me. I am so grateful it has worked for me. I can't even tell you how much more confident I feel in myself now. The only thing is, I had awful blackheads and they're better because they come out easily, but they're still there.... But I can't complain because it's cleared up my skin!
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November 15, 2014
expensive and left me with scars
I've used Epiduo for 7months. I suffer from cystic acne and didn't see much improvement, on the contrary, after I started using this medicine my skin is now full of indented scars, they look like holes pockmarks and I never got scars from my acne before using epiduo. These scars can't be concealed with make-up, my skin is ruined. The only thing I can say positive about this drug and will give 2 stars is that it helped me to get rid of black spots mainly on the nose and chin but it did nothing for my cystic acne and it was very expensive. Unfortunately it didn't work for me but it might help you.
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August 14, 2014
Excellent product!
My derm recommended it to me just few days ago and so far it has been an excellent product. Doesnt make my skin red like other bp products, but it does tend to dry your skin a lot so after applying a thin layer of it I use Hyalix (in my country it has that name) that is a very simple hypoallergenic hidratation gel.
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August 3, 2014
Worked like a miracle!
I have tried so many products but when a new derm gave me a sample, I could not believe how it worked overnight. I use it for spot treatments, both of existing bumps and some that I could only feel coming up, and in the morning - gone. You need very, very little for this to work. When I read reviews that say it felt greasy, you're using too much. I can't believe my old derm never suggested it. I would definitely recommend trying this - just use as directed, or less.
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October 30, 2013
Works with persistence

Pros:

Gets rid of redness
Flattens bumps

Cons:

Burns for few days
Must be used every day
Makes skin dry, flaky, and tight

Epiduo is a fine product, at first I didn't think it was working, all it did was sprout more acne in some places. But after a few months it does its job nicely. For the first few days it will also burn your skin, but you get used to it. It should probably be used with a cleanser to get maximum effects. It flattens bumps and also takes away redness which is great! I haven't used it for that long but it has shown results and other people have told me of its effect. It also makes your skin very dry and flaky and makes it feel tight.
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October 8, 2013
Great for moderate acne!

Pros:

Clears acne

Cons:

Expensive
Smells horrible

I got epiduo when I was 16. My doctor prescribed me epiduo because I was getting moderate acne on my chin and T-zone. It didn't work very well the first two weeks or so, but it started working after that. The only reason I'm giving this 3 stars is because it's $70 WITH insurance, and it smells HORRIBLE, I don't recommend putting this anywhere near your nose, because you'll be able to smell it all day. Other than those two things, it's a great product!
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August 2, 2013
So far, I'm loving it!

Pros:

Works well
No burning, stinging, itching
Efficient

Cons:

Expensive

To start this off, I am 15 years old, and I have had mild-moderate acne since age 12. My dermatologist recommended Epiduo, and so I have been using it for about 3.5 months now, and I really like it. I've been using little sample sizes every night, but when I went to the pharmacy the other day to get the full size, they said it costed over $200, and there's no way I'm paying for that. My derm said with insurance, it'll cost me about $25-30, which is pretty good. But as for results, I am pretty much clear, probably about 90%, whereas before I was around 30%. Also, no stinging, itching, burning or sensations for me. Probably because my skin is so used to benzoyl peroxide after using it for years. If you get the chance to use Epiduo, I would highly recommend it.
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July 16, 2013
Oh the frustration

Pros:

No more forehead whiteheads
No more bangs

Cons:

Irritation
Doesn't work for my entire face
Losing hope

So I started getting acne around 14 and for years I used OTC products to control it and had relatively nice skin. Over time the product ingredients I was using (benzoyl peroxide, tea tree oil, salicylic acid, etc) lost their effectiveness and so almost a year ago I realized that they no longer worked for me. I am now 20. I began getting breakout after breakout which left much scarring. So after about 6 months of trying all kinds of remedies I decided that I needed to go to a dermatologist. I went and was prescribed epiduo and clindamycin 1% pads. What can I say? Epiduo has mostly been a huge disappointment to me as it has not really changed anything. I have been using it for two months. I went through the initial breakout,dryness, flaking, redness, and irritation in hopes that by the end of it all my acne would be better. However all that effort was to no avail as my acne on my jaw has only gotten worse even after the initial breakout. I had a horrible ib for two to three weeks. After that my skin got better but only briefly. Now my skin is absolutely awful and epiduo hasn't done much to help it. I use it religiously every night to no avail. No change. The dermatologist said epiduo should help with the inflammation and whiteheads I keep getting but no. The only positive is that I don't get much forehead whiteheads now and so I have resorted to growing out my bangs as I no longer need them to cover my forehead acne. However my cheeks look ridiculous as they're covered in scars and new pimples. As soon as one zit goes away two or three more form so it's a constant cycle. Epiduo does seem to help slightly with scarring though but it doesn't do what it's supposed to do for me. I guess my acne is more stubborn than I thought. After all the positive reviews I was hoping it would work for me but at this point I doubt it. I hope it works for you guys though.
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May 20, 2013

Pros:

Clears up skin

Cons:

Redness,dryness
not consistent or permanent
Very painful to use (burning sensation)

I got prescribed epiduo 9 months ago and it started working almost immediately. There was a pretty bad initial breakout and the dreaded flaking of the skin but after about 2 weeks I could tell it was working and by month 3, I was completely cleared up. I was incredibly happy with the results, I stopped worrying about my skin and I felt like a changed person. HOWEVER about a month ago I started to notice my skin gettting progressively worse and worse. At first I thought it was just a breakout but nothing seemed to be improving so I went to my derm and he prescribed me Tazorac. My skin is currently horrible but I'm hoping to find a more permanent and consistent treatment than epiduo. I think one of my mistakes while on epiduo was maybe that I used too much of it and my skin eventually became resistant to it but who knows.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.