Topical Retinoid / Topical Antibacterial
Reviews
3.7
579 Reviews
Topical Retinoid / Topical Antibacterial
Efficacy
67%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid / Topical Antibacterial
Side Effects
Low-Medium
Topical Retinoid / Topical Antibacterial
Acne.org’s Real World Take
A way of using benzoyl peroxide in combination with the topical retinoid, adapalene, that studies show works a bit better than benzoyl peroxide alone. Comes with side effects for the first weeks and can bleach fabric. Note: When used correctly, benzoyl peroxide on its own can completely clear the skin.
Topical Retinoid / Topical Antibacterial
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Adapalene / Benzoyl Peroxide (Epiduo®)
Compare To Other Treatments
5
38.2%
4
27.3%
3
11.1%
2
8.6%
1
14.9%

Used Adapalene / Benzoyl Peroxide (Epiduo®)? Rate It:

Choose from 1 to 5 stars
June 18, 2010

Pros:

-It's a product made with two products that are considered the best in the treatment of acne.
-Your acne really go away.
-Skin without spots.

Cons:

-Skin a little bit dry.
-You can't go out without sun block, because you can have burns.

My skin was terrible. I didn't know what to do. So, I decided to go to my dermatologist and see what I can do to improve my skin. When I buy this product and I started to use, I can saw clearly an improvement in my skin. I bought make products without oil too, because we have to use products to our tipe of skin, and skin with acne problems usually are oily. I really recommend this. My skin know is pretty good and I improve my self steem again.
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March 2, 2016
Used to have oily skin(and alot of clogged pores and whitehead break outs) Epiduo saved me!
Used it for 2 months straight every night. At first it burned ALOT but then after 2 weeks i got used to it. After about a week my skin was clear and no problem. I'm not using it anymore and i'm fully recoverd.
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July 20, 2016
I've always had little closed whiteheads around my mouth and chin but I started using epiduo a week ago today and they've tripled and gotten worse. will they clear up?
December 12, 2011

Pros:

Got rid of my severe acne completly
gave me my life back
makes scars and acne go away
cheap to buy
easy to use

Cons:

initial breakout was horrible acne doubled in severety

the initial three months of using this will be bad but if you can break through that you can get amazing results, i used to have tons of scars and red skin with 10 large whiteheads and some cysts on a consistant bases and now i have one small pimple a day! Been using it for a year!
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April 26, 2011

Pros:

worked fast, near perfect skin. very pleased

Cons:

slight burning, some flaking

for me epiduo worked in one week! i was on accutane for 5 months but after i was off of it for a few months, some slight acne came back. dermatologist gave me this and wow....my face is back to being clear. i couldn't be happier. no more worrying about my face. thank you!
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December 8, 2010

Pros:

Kills existing acne quickly, prevents new breakouts, skin is very smooth, fast and easy to apply, lasts a while

Cons:

A little bit of dryness (moisturizer takes care of it though), expensive, smells funny?

Ive been using epiduo for over a month, and I finally found my perfect regimen. it is as follows, and I recommend it to everybody: Morning: Was face with purpose cleanser Apply Rx called Prascion (sodium sulfacetamide and sulfer) Night: Purpose cleanser again Nickel size of epiduo One pump of cerave moisturizer when the epiduo is completely dry Vitamin Regimen: 60mg of opti zinc 2000-3000mg of fish oil/krill oil (GNC) 1000-2000 iu of vit D 2 garlic pills I current do Jiu Jitsu and boxing, both of which my face gets hit, scratched, and rubbed. Doing this regimen I have hardly broken out from this. My face looks better than it has in years, and I feel like epiduo is the staple product. Also, the vitamins are essential to battle acne from the inside out. Seriously consider trying all of these things!
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October 17, 2010

Pros:

It hasn't dried out my skin
It has killed alot of my exsisting pimples
Leaves my skin feeling smooth and has improved the tone of it.

Cons:

Isn't preventing pimples completly but I've only been on it for 3 weeks.
Skin peels alot more, but it's not dry feeling. The skin just peels off over the pimples which can be annoying.

I was prescribed Epiduo along with Solodyn. I had to stop taking the Solodyn because of the horrible side effects, and now I am just using the Epiduo. I get pretty bad breakouts and the Epiduo has significantly decreased the amount of pimples I get, although I still get a few new pimples every week. I have noticed that the pimples I do get, go away alot quicker because of the Epiduo and also they are not nearly as painful. I used to get really deep, painful pimples on my cheeks. They would get really inflamed and have tons of pus in them. I'm so happy that the Epiduo eliminated that type of pimple because there's nothing worse than your face hurting and looking gross. Thanks Epiduo for that. The Epiduo has made my skin peel over the pimples crazily. I guess that is a good thing, because it makes them smaller and that's a sign they are healing. One more thing I want to address is everyone complaining about Epiduo burning and itching. Today I was using it and I accidently got some on my neck, and now I understand the burning sensation. When I use Epiduo on my face, it doesn't burn or itch but on my neck it feels horrible. I don't think Epiduo makes my face burn or itch because I've used so many different acne products on it, and some that are stronger and have a higher percentage of benzoyl peroxide. My face has gotten use to strong acne products but my neck hasn't. Overall I would highly recommend everyone with acne try Epiduo.
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September 6, 2010

Pros:

Works fast, it cleared up my skin in 4 weeks or less while using it daily. It helped fade old/new acne scars.

Cons:

Minor irritation, burning when I first started using it, some peeling and dryness.

This product, after using several over the counter acne products, has been the most successful in clearing up my acne. My dermatologist recommended I try this along with the pills Doryx and another topical Aczone and after a year or so of using all three products my skin has never been better. I apply Epiduo every night, it doesn't dry out my skin anymore. It helps fade away my old acne scars and helped lessen the redness of my cystic acne. I love this product and I hardly break out at all anymore. I would definitely recommend Epiduo, it worked for me, it can work for you:)
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June 24, 2017
AMAZING besides a few side effects
I am a teenage girl who has suffered from acne for 5 years (12-17) - I felt like I had tried nearly everything and started to get desperate about clearing my worsening facial, chest and back acne. Finally I tried this stuff and I made the mistake of applying every night for the first week and the more sensitive skin (neck and face) went bright red and felt like it was on fire. As well as this, my skin was so incredibly itchy that I had to excuse myself from class just to get an ice pack to cool down my back. But god was it worth it. About three weeks in and my skin is so silky smooth and nearly completely clear. The only thing I can say is that my skin is still super sensitive to sweat and water but honestly, for me, it is totally worth it.
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December 9, 2016
My skin has transformed!
For the past few years I've had mild acne, a spot here and there most of the time, but major flare ups during certain times of my menstrual cycle. My biggest problem was whiteheads- no redness, just a ridiculous amount of tiny bumbs under my skin mixed with blackheads that just wouldn't go away no matter what scrub, cleanser, or pore strip I used. A few nights a week I'd sit in front of a magnifying mirror and squeeze the crap out of my face (which I know now only made matters worse, as it just pushed bacteria deeper into my skin and left me with scarring that I am still dealing with). Finally after months of frustration and insecurity I went to a dermatologist. I was prescribed an antibiotic (Morgidox), a benzoyl peroxide 10% cleanser, and epiduo forte. During my visit to the dermatologist it was recommended I get a facial before starting the medication to get all the gunk that was in my skin. THIS IS SO IMPORTANT. I see so many people on here complaining about how epiduo broke them out horrendously. Yes, it's a retinoid, it pushes out all the bacteria that's deep into your skin to the surface so you can get rid of it. By getting a facial you can save yourself a face full of zits because you've already extracted everything. Also, the antibiotic Morgidox kills bacteria in the skin and also helps prevent break outs. With these tools you can essentially prevent the horrible flare ups that most complain about upon starting epiduo. Now, I won't deny the first few weeks of the treatment were not easy. I experienced extreme dryness, my face peeled nastily, makeup looked awful, and upon wearing it my face felt excruciating itchy. Upon applying the treatment I felt an extreme burning and stinging that left me with headaches that caused me to loose sleep. It is strong!! But now... 5 weeks after starting epiduo, I couldn't be more happy. I've learned how to deal with the dryness (I've had to change my entire skin routine as my skin was oily and is now dry and sensitive), my scars are fading, and even though I'm still getting facials every 2 weeks to remove blackheads, not a spot in site. My skin is so soft and looks airbrushed in some areas. I'm only on the 5th week and the results are astonishing, the compliments I get on my how much my skin has cleared up are so wonderful. So, my advice is take the precautionary steps before starting this treatment, load up on moisturizer, and watch your skin transform!
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December 24, 2017
hi, what moisterizer do you recommend? :)
May 16, 2016
Epiduo helped my skin so much
I'm 14 years old but I've have acne for about 2 years and it's just slowly gotten worse. Around last year my entire forehead was covered in acne (mostly just my forehead) and I tried everything to get rid of it but nothing worked. About 3 months ago I finally made my first visit to the dermatologist where she recommended me Epiduo since I had mostly comedones. I looked it up and was honestly terrified because almost every review said it burnt very bad, but i tried it anyway bc dermatologist knows best lol. I started every other day and applied a very thin layer so my skin would get used to it ( I think a lot of people forgot this step). I never experienced any burning so I moved on to daily uses after I washed my face with cetaphil, and the next morning I would use cetaphil lotion. My skin did get dry at one point but that cleared up quickly. My pharmacist is also very helpful and told me it would make my skin sensitive to the sun, so on sunny days I put on a little bit of sunscreen. My face has cleared up so much and I'm so happy with the results so far. I really think anyone debating trying this product should take the plunge, it's worth it.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.