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Licochalcone (Licorice Root Extract)

Powerful Molecule Contained in Licorice Root Extract, Isolated for Our Use

Last updated: September 05, 2018

Article Summary

Licochalcone is a molecule derived from a specific species of Chinese licorice root that helps calm acne-prone skin. It is what gives Acne.org Moisturizer and Acne.org AHA+ their characteristic yellow color. 

What Is It?

Licorice root has been used in skin care for millennia. According to the National Cancer Institute it has, "potential anti-inflammatory, antioxidant...activities." Licochalcone is a molecule contained in licorice root extract which helps control oil production, and is anti-bacterial as well as anti-inflammatory. In short, it helps calm and soothe acne-prone skin. It is suitable for sensitive skin, and imparts a natural yellow color to products.

It is a key ingredient in both the Acne.org Moisturizer and Acne.org AHA+.

Licochalcone - A Key Ingredient in Acne.org Moisturizer and Acne.org AHA+

My Bottom Line on It


  I am skeptical of pretty much any extract that comes along, but when I learned about licochalcone at the Society of Cosmetic Chemists meeting 6 years ago, I found it intriguing. I decided it was worth a closer look. After doing more research, I found myself impressed by the company that makes it and by its potential. Several trustworthy mentors of mine in the acne community also espoused its properties specifically for acne-prone skin. But as we all know, the proof is in the pudding. So I worked with our team of biochemists to make some test products with this ingredient, I absolutely adored them and what they did for my skin."


Licochalcone (Licorice Root Extract) - Acne.org

One Challenge It Presents

It is very expensive ($6000 per kilogram), so it increases the cost of products. Thus you will not see it used in many products.

Where to Get It

Our store. Licochalcone is a key ingredient in  Acne.org Moisturizer  and  Acne.org AHA+ (10% glycolic acid plus lichochalcone).

Licochalcone (Licorice Root Extract) Effects in the Skin

The Experts at Acne.org

Our team of medical doctors, biology & chemistry PhDs, and acne experts work hand-in-hand with Dan (Acne.org founder) to provide the most complete information on all things acne. If you find any errors in this article, kindly use this Feedback Form and let us know.


  1. "Definition of licorice root extract." National Cancer Institute Drug Dictionary. 11 Jun. 2008.

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