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Stem Cells for Acne Scar Repair (SCIENCE FACT, not science fiction!)

 
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(@aplaceinthesun)

Posted : 06/18/2010 1:00 am

Where is BRD ? his really helpful pls come back, even only for once in a while.

I've been browsing but haven't been active here for a long time.

I really want to try this but caught impetigo which keeps on recurring and

giving me more scars.

 

Also where is icaretohelp, maybe he has good results and don't need to

come here anymore. Anyway miss them both because they really gave

me hope when i was feeling down !

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(@prague)

Posted : 06/22/2010 1:52 am

Where is BRD ? his really helpful pls come back, even only for once in a while.

I've been browsing but haven't been active here for a long time.

I really want to try this but caught impetigo which keeps on recurring and

giving me more scars.

Also where is icaretohelp, maybe he has good results and don't need to

come here anymore. Anyway miss them both because they really gave

me hope when i was feeling down !

Icaretohelp went to khan and had good results. Follow his thread. I'm waiting for BRD myself..He is to return sometime this month.

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(@epcortek)

Posted : 06/24/2010 2:25 am

Where is BRD ? his really helpful pls come back, even only for once in a while.

I've been browsing but haven't been active here for a long time.

I really want to try this but caught impetigo which keeps on recurring and

giving me more scars.

Also where is icaretohelp, maybe he has good results and don't need to

come here anymore. Anyway miss them both because they really gave

me hope when i was feeling down !

Icaretohelp went to khan and had good results. Follow his thread. I'm waiting for BRD myself..He is to return sometime this month.

 

I have a feeling we wont see bird anytime soon. Im sure we would have read a medical journal or article about him by now if his treatments showed great results.

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(@v_singh)

Posted : 06/30/2010 2:29 pm

BRD - If you are still reading this thread, please could you post the before and after photos with facial features blocked out. You mentioned to me that you would do this in June (1 year after your patients had the treatment). If you could post those photos up as soon as possible i would really appreciate it. Thanks

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(@lavish-habits)

Posted : 06/30/2010 9:52 pm

does anyone have his email?

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(@prague)

Posted : 06/30/2010 10:29 pm

Today is the last day in June; still no BRD. I hope he shows. We have all patiently been waiting. Even if the results aren't perfect we would still love to know.

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(@zante)

Posted : 07/01/2010 7:28 am

Been following this thread in a cautiously optimistic capacity for a while now, registered just to post.

 

I sincerely hope we all get some closure on this. Life is full of broken promises which is why I make it my business not to invest too much emotion in this sort of thing. I can't deny, however, that I find it difficult to turn a blind eye in this case.

 

I will continue to watch this thread and, for the first time in a while, hope for the best rather than prepare for the worst.

 

Kind regards

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(@epcortek)

Posted : 07/01/2010 6:43 pm

Been following this thread in a cautiously optimistic capacity for a while now, registered just to post.

I sincerely hope we all get some closure on this. Life is full of broken promises which is why I make it my business not to invest too much emotion in this sort of thing. I can't deny, however, that I find it difficult to turn a blind eye in this case.

I will continue to watch this thread and, for the first time in a while, hope for the best rather than prepare for the worst.

Kind regards

I think in regards to stem cell treatment of scars we should be watching out for progress made by a scientist named Hans clevers. Clevers it isolating the parent stem cell that forms all the components of skin including pores ,hair folicles and not fat tissue. He has dubbed it the lrg6 stem cell.

From what i know of bird, he is simply using fat and trying to culture stem cells from that. This would simply create, volume and really be best used on maybe mega deep scars and some rolling scars. But you will never get the surface of the scar to look right. Am i correct in my assumptions of birds methods. if not post here and keep this thread roling .

In anycase, we would like to see you post back bird, for better or for worse 🙂

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(@epcortek)

Posted : 07/02/2010 1:39 am

Scientists find aoemothera

of all skin cells

LONDON (Reuters) a Scientists have found the

aoemother,a or origin, of all skin cells and say their discovery

could dramatically improve skin treatments for

victims of serious wounds and burns.

Hans Clevers and a team of Dutch and Swedish researchers

conducted a study in mice and found that

the stem cell that gives produces all the different cells

of the skin actually lives in hair follicles.

The findings, which they say will translate for human

use, mean it may be possible to harness these

stem cells to help with wound repair or skin transplants

for burns victims, they said in a study in the Science

journal on Thursday.

aoeThis is the mother of all the stem cells in the skin --

it makes all the other stem cells,a Clevers, of the Royal

Netherlands Academy of Arts and Sciences in Utrecht,

told Reuters in a telephone interview.

aoeThe same stem cells exist in humans, we can see

them, and the promise is that these cells are probably

going to be much better than anything we have had to

date at making new skin.a

The skin has three different populations of cells --

hair follicles, moisturizing sebaceous glands, and the

tissue in between, known as the interfollicular epidermis.

Stem cells are original cells, or drivers, from which

all human cells develop.

Scientists had previously thought that stem cells in

each of these three skin populations were capable of

producing their own cell type, but until now, a aoemothera

stem cell which produces all three types had not been

found.

Cleversa team found that a group of stem cells that

live in hair follicles and which have high levels of a

gene called Lgr6 are the original epidermal stem cells.

In tests on mice with wounds, they found that Lrg6 cells

around the wound drove new skin growth and repaired

the skin.

Scientists are already able to grow new skin in laboratories

using tissue from existing skin cells from patients

who have been badly burned, but the new skin

is often brittle, dry and does not have hair -- making it

look unusual.

Clevers said the advantage offered by the aoemothera

stem cell finding would be that they could grow skin

from its original basis -- allowing it to be aoereal new skina

with moisture from sebaceous glands and the ability to

grow hair.

He said researchers now need to learn how to isolate

the Lrg6 cells from human skin. That could take 2

to 3 years.

aoeWe are learning how to grow the mouse cells in

culture. Once we know how to do this and can isolate

the human variant, we should be able to grow human

cells as well,a he said.

aoeSince there is a lot of experience already with growing

and transplanting skin for burn wound patients, it

should be relatively easy to incorporate the new stem

cells ... and conduct trials in patients.a

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(@jack31)

Posted : 07/03/2010 6:15 am

I always listen miracle things... :think: ‚¿but when this will be avaible for us? 5 years, 10 years? when will can go to the doctor and pay for scars tissue repair treatment 90% or 100% of successful?

 

Wait for the moment....

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(@epcortek)

Posted : 07/03/2010 12:16 pm

Well its already proven effective in mice. So it already exists, like the post says, another 2 year before you will see it used for burn victims and then im sure within another 2-3 years you will see it being used for treatment of scars. Im going to make a guess of 5 years maximum. Dont forget though this stem cell creates only the skin.For deep sunken scars it will only coat a fresh layer of skin on them. You will need something like birds approach in combination.

 

Hey, I do not have acne.....Do you think you could draft up a cunning email to hans clevers and see if he will release photos, and documentation on his findings pertaining to skin regrowth on his lab rats. I ask you because you speak his language from what i have read, and also you have been in contact with so many researcher regarding regenerative medicine.

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(@lapis-lazuli)

Posted : 07/04/2010 4:31 am

Hey, I do not have acne.....Do you think you could draft up a cunning email to hans clevers and see if he will release photos, and documentation on his findings pertaining to skin regrowth on his lab rats. I ask you because you speak his language from what i have read, and also you have been in contact with so many researcher regarding regenerative medicine.

Sure. I'll see what I can do.

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(@epcortek)

Posted : 07/05/2010 1:07 am

Here is the abstract to hans clevers research. Anyone have access to it ?

http://www.ncbi.nlm.nih.gov/pubmed/20223988

 

Here is another abstract by CAdric Blanpain which mentions LRG6 in skin regeneration

http://www.ncbi.nlm.nih.gov/pubmed/20360726

 

And here is an article explaining cedrics findings titled, Stem CellS

Skin regeneration and repair(may 2010) He discusses Lrg6 wound repair

http://blanpainlab.ulb.ac.be/images/pdf/Bl...Nature_2010.pdf

 

I emailed Cedric on the 8th of july. Lets see if he responds.. Hey i do not have acne , did you manage to email clevers about his rats ?

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(@nozleb)

Posted : 07/12/2010 5:36 am

hi mates

the stem cells has been in market since 1998 and it was mainly used for scar repair in south korea under the name of: ADIPO CELL, you can search for adipo cell in google.. dont put your hopes so high because, if this was since 1998 and we are now in 2010 so it has been 12 years since that technique has started and if there were excellent results it must have been spread all over the world.\

 

Finally i hope i am mistaken and miss a lot of information but what i am sure of is that to get rid of the scar, first of all we should remove the scar tissue and then proceed with stem cells or whatever else

 

 

Regardssssssssssss

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(@faizalj19)

Posted : 07/14/2010 5:53 pm

Hi Guys,

 

Just about finished 4 months of stem cells and I had no results :(

 

You can see my latest post here:

 

http://www.acne.org/messageboard/Experienc...Tr-t260545.html

 

I am seeing Dr Khan on Saturday. I will keep everyone updated :)

 

Regards

Faizal

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(@mercs22)

Posted : 07/15/2010 3:10 am

please come back BRD :(

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(@epcortek)

Posted : 07/15/2010 4:51 am

hi mates

the stem cells has been in market since 1998 and it was mainly used for scar repair in south korea under the name of: ADIPO CELL, you can search for adipo cell in google.. dont put your hopes so high because, if this was since 1998 and we are now in 2010 so it has been 12 years since that technique has started and if there were excellent results it must have been spread all over the world.\

Finally i hope i am mistaken and miss a lot of information but what i am sure of is that to get rid of the scar, first of all we should remove the scar tissue and then proceed with stem cells or whatever else

Regardssssssssssss

Well the problem i have with your post is that they have created skin using stem cells. It has been used on burn victims in hospitals. It is proven. But past advances in stem cell used to create skin is not effective as the skin created is not really functional, it is dry and brittle because is does not contain all the componets of skin. The latest research done by clevers with stem cells found in the hair follicle is supposed to contain everything from sweat gland, sebacous glands collagen ect. So we will have to wait to see what else comes from this Lrg6 discovery. If anyone finds some new research regarding Lrg6 , please post it here. The only thing i have found is clevers press release statements on march 12, and a article posted by another scientist cedric.

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(@nozleb)

Posted : 07/15/2010 7:57 am

 

Well the problem i have with your post is that they have created skin using stem cells. It has been used on burn victims in hospitals. It is proven. But past advances in stem cell used to create skin is not effective as the skin created is not really functional, it is dry and brittle because is does not contain all the componets of skin. The latest research done by clevers with stem cells found in the hair follicle is supposed to contain everything from sweat gland, sebacous glands collagen ect. So we will have to wait to see what else comes from this Lrg6 discovery. If anyone finds some new research regarding Lrg6 , please post it here. The only thing i have found is clevers press release statements on march 12, and a article posted by another scientist cedric.

 

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(@maldition)

Posted : 07/15/2010 8:30 am

and in the end...

 

science fiction.

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(@mr-president)

Posted : 07/15/2010 8:47 am

and in the end...

science fiction.

lol guys i doubt anything is going to happen in the near future, so why you bother with this thread i do not know. if you want anything to happen in this world - you have to make it happen. all i see is eterna going on about how hopeless it all is and it ending negatively. so much talk and so little action.

the way you keep going on about this treatment, i think you should probably make it yourself. if thats impossible, wait a few years before something new actually comes out.

all you are doing is wasting your time when you should be focusing on present treatments.

otherwise there is a possibility, you could be here forever. how sad 🙁

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(@elevate)

Posted : 07/16/2010 1:57 am

hi sydney,

 

the procedure that the OP describes is in fact a current and real procedure. there have been discussions about it in other threads related to dr. kahn. although it is not living up to people's expectations, people know about it and have seen actual results (albeit not great results) because of this forum. the fact is, even though the results are not profound, we have made a lot of progress since we started talking about it over a year ago. people have tried it, and they have shared their results, and as a result everyone is more informed. their bravery and their participation should be commended.

 

this thing will continue to evolve i think, and scientific progress is always wrought with failure. it's a part of the process. disappointment happens, but i think people can be more positive about the steps we have made directly because of this thread and because of the participation from people on this thread. i don't expect people to be entirely hopeful, but we can certainly be more positive...there's a difference.

 

 

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(@lavish-habits)

Posted : 07/16/2010 5:03 am

yes well said^ and remember that this procedure is still really new

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(@jamesj)

Posted : 07/22/2010 5:38 pm

Hey everyone,

 

I have been reading this thread (and other related threads of which I think there are 2 or 3) for a little over a week now. I'm sure like many of you out there, upon first reading this thread I had a lot of hope. However, that hope is slowly diminishing as the success of this treatment isn't being talked about as much and there is no sign of the research done by BRD. However, logically, the ideas of stem cell treatment make a lot of sense.

 

I have mild to moderate acne scarring on my temples and forehead that I have been trying to clear up for about 8 years now. I've tried chemical peels, cooltouch laser, 1 punch excision and 2 fraxel treatments (with microdermabrasion). I believe (strongly) that the fraxel has damaged my skin as it now has a very rough look to it with enlarged pores and fine lines.

 

I have come to the realization that perfect skin may not be in the cards for me and I'm really ok with that. I would just like my normal texture with some of the more prominent scars being softened. Thus, I have put some faith in stem cell therapy.

 

I live in Los Angeles so going to London to see Dr. Khan is not out of the realm of possibility but would be very difficult to say the least. I thought about seeing some of the Dr.'s mention here in Los Angeles (Newman and Calabria), but am somewhat hesitant after reading some negative reviews for both of them.

 

I really don't know what to do at this point because I don't want to rush into a rash decision but I would also like to move on with my life and put the thought of acne scarring behind me.

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(@michael24)

Posted : 07/22/2010 6:04 pm

Hey everyone,

I have been reading this thread (and other related threads of which I think there are 2 or 3) for a little over a week now. I'm sure like many of you out there, upon first reading this thread I had a lot of hope. However, that hope is slowly diminishing as the success of this treatment isn't being talked about as much and there is no sign of the research done by BRD. However, logically, the ideas of stem cell treatment make a lot of sense.

I have mild to moderate acne scarring on my temples and forehead that I have been trying to clear up for about 8 years now. I've tried chemical peels, cooltouch laser, 1 punch excision and 2 fraxel treatments (with microdermabrasion). I believe (strongly) that the fraxel has damaged my skin as it now has a very rough look to it with enlarged pores and fine lines.

I have come to the realization that perfect skin may not be in the cards for me and I'm really ok with that. I would just like my normal texture with some of the more prominent scars being softened. Thus, I have put some faith in stem cell therapy.

I live in Los Angeles so going to London to see Dr. Khan is not out of the realm of possibility but would be very difficult to say the least. I thought about seeing some of the Dr.'s mention here in Los Angeles (Newman and Calabria), but am somewhat hesitant after reading some negative reviews for both of them.

I really don't know what to do at this point because I don't want to rush into a rash decision but I would also like to move on with my life and put the thought of acne scarring behind me.

It is more than likely that the chemical peels caused those side effects. I have never heard of any type of fraxel causing that. It is however a common complaint of chemical peels.

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(@v_singh)

Posted : 07/23/2010 2:16 am

Hi Guys,

Just about finished 4 months of stem cells and I had no results 🙁

You can see my latest post here:

http://www.acne.org/messageboard/Experienc...Tr-t260545.html

I am seeing Dr Khan on Saturday. I will keep everyone updated 🙂

Regards

Faizal

No results ?!

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