Ziana : Clindamycin (1.2%) and Tretinoin (.025%) Gel

When I was around 18 my skin became extremely sensitive and I got a lot of white heads and small pimples daily. It wasn't so bad but it was just all over my cheeks and easily coverable but I could never leave the house without makeup. I went through that for about two years and finally decided to go to the dermatologist. She prescribed me Ziana and I started using every other day before I went to bed for the first three weeks and then after that every night. The first month or so it calmed my existing white heads but I noticed a few new ones. It wasn't as bad as many others have experienced but I did get pimples (bigger ones than when I wasn't on the medication) but they would go away quickly. I also noticed they scarred darker than my acne in the past. I also noticed by face burned a bit when I washed it or when I went to the gym and sweat because the medication does make it sensitive for the first couple of months. I also did experience some minor flaking and peeling. I've now been using it for about 6 months and I've never seen my face so clear! It cleared up all the marks, and I haven't got any acne for the last month. The only annoying part is that around my chin it still flakes a bit (but that can be fixed easily with lotion) and my t-zone is a little oily (which was never the case before). But in my opinion those things can be fixed so easily and I love my skin now. I would definitely recommend this for anyone!! I have mild-medium acne and It definitely worked wonders for me.

After trying every over the counter topical and a variety of topical's prescribed by my dermatologist, they decided to put me on ziana. I have light to moderate acne and it is very hormonal. The ziana helps maybe a little, but not very much. I get chemical peels. Laser treatments, I use the Emergency spot treatment, I'm on an oral antibiotic and yet I still continue to have breakouts. I have exhausted all my options and have decided to try birth control(mircette). I feel like out of all the things I do to help my breakouts the ziana only helps 10%.

I was breaking out a little bit while on Differin so the dermatologist recommended I try out Ziana. What a bad idea! Three weeks non stop of breakouts! And Ziana breakouts leave reddish/brown spots on the skin. After 3 weeks of suffering, I gave up. Now I'm back on Differin and my skin is slowly clearing up. What a nightmare. Also - Ziana made my skin oily and when I wore makeup it would 'sit' on top of my skin. I would not recommend.

I have moderate acne and use this project twice or three times a week at night.

After stopping birth control, I developed acne unlike any I had ever had in my life (including my teenage years when I had mild acne - I am currently 37 years old). I knew that my hormones would take a while to get back to normal but after two months of dealing with a completely acne covered face (bumps all over as well as a few cysts), I went to the dermatologist who prescribed this. I have somewhat sensitive skin and had used Retin-A in the past (teen years). It had dried out my skin and made my acne much worse before it got better, so I was skeptical. I use this once a day at night after I wash my face. In the interest of full disclosure, I also use PCA Skin acne gel in the morning after I wash. Additionally, I use a light moisturizer in the morning after the acne gel dries. (FYI - My doctor had suggested I start out using this every other night, but I didn't need the adjustment time as my skin was SO oily and I did not fear it getting too dry.) This drug has worked wonders for me. After 5 weeks, my skin is 99% clear (a few very minor bumps - pretty normal for me on or off birth control), and it looks better than it has in years. My doctor had said that my skin could get worse around the 4-6 week mark, but I have experienced an overall general improvement as the weeks go by. The box insert said a worsening of the acne around 2-4 weeks, and I didn't see a major improvement until about 4 weeks, although I didn't think the medicine ever made my skin worse at all. I would highly recommend this to anyone with acne for whom Retin-A, alone, is too drying. The added benefit at 37 years old is that I might see some improvement in skin tone and prevention of wrinkles:)

I suffered from acne for 2 years and it's been a pain in the butt. I tried everything and when I say everything, I mean almost everything. I tried retin-a micro 0.25% and 0.4%, epiduo, solodyn, acanya, aczone, minocylcine and finally ziana. I was really afraid to try ziana because I read about how it had really bad purging and I was afraid. However, I decided to give it a try since I was losing hope. I saw a difference in 1 day. It was amazing. I put it on at night and woke up with less bumps on my temples. I had no purging whatsoever and it's only been little over a week and it has done amazing to my skin. The pimples are slowly clearing up and I'm hoping it can fade my acne scars. All I have to say is, give it a try. I love ziana and I feel confident again (:

First, I want to share my background. I have never had a problem with acne. I have always had very smooth clear skin, with an occasional outbreak. I started washing with proactive in 2006 when I was 18 for prevention of those minor outbreaks (I don't recommend this because it destroys your skins natural barrier). Two years ago, in 2011, I started getting a cystic pimple every couple months, that I would handle by getting a cortisone injection. Not a big problem. Then Last year, in May 2012, I got my mirena birth control removed. I had an AWFUL outbreak. Huge pimples that wouldn't go away. One swelled up after it popped when I washed my face.. it was half the size of my forhead. I had cystic pimples, surface pimples, and clogged pores. My dermatologist put me on Doxy, spirolactone, and retin-A. After a few months, and a couple deep cleansing facials, my skin was clear... but I still had scars. In August, I decided to stop using Retin-A because my skin was still red. I started using Pro-Active again, and continued taking Doxy and Spiro. My scars went away in less then a month, and I had completely clear beautiful skin for about 6 months. In February, 2013, my skin started looking red and a little oily. By April, I started getting minor clogged pores that would go away fairly quickly, and I started getting cystic pimples every once in a while. I decided to stop washing with Pro-Active In june because I found out that it can cause oily skin. I also stopped taking doxy because it wasn't preventing acne anymore. I started using Jojoba oil to cleanse, but this only lasted a month because it was cause tiny little white heads to surface all over my face. I started using Cerave to cleanse. It doesn't create acne on my face. I did have clogged pores on my chin and forehead from the Jojoba oil. They are skin colored tiny bumps. I had a similar reaction years ago. I've now learned that it just doesn't agree with me. By August, I was getting more and more cystic pimples. Usually only one at a time, but when one would go away, another would appear. My dermatologist prescribed me Klarons. This did nothing for my skin. The cystic pimples kept coming and the clogged pores stayed where they were. I used it for over a month before I stopped. In September I decided to risk using Proactive again. It did nothing. It didn't make it worse or better. My skin was still pink, still a little oily, still had the clogged pores, and I was still getting those dang cystic pimples. This is when the Dermatologist prescribed me Ziana........ On September 25, 2013 I started using Ziana, and also had a bad cystic pimple injected. First week: (9/25) peeling. Red face. surface acne and scars start to go away. No change to clogged pores. Cystic on on left side of nose goes down but still under the surface. Second week: (10/2) less peeling. Red face. Scars fading very quickly. No change to clogged pores. Cystic on on left side of nose starts coming back... Two heads. Cystic appears on right side of nose. Third week: (10/9) (Stopped spirolacton on 10/11) New Small pimples show up but come to a head and go away quickly with in a couple days. Oily skin. Less peeling. Red face. Old scars almost gone. New scars fade quick. Both cystic pimples still present but no pain. One deep clogged pore is gone after popping it, but 8 remain. Forth week: (10/16) Tiny amount of peeling. Red face. Oily skin. Old scars almost gone. New scars still fade quick. Both cystic pimples still present, the one on right is forming a white head. Deep clogged pores still there. I'm getting the two cystics injected tomorrow and I will be back to update how this week goes. I have my fingers crossed...

THIS STUFF IS AMAZING!! my (short) story: my birth control broke me out in cystic acne all over my chin.. which if it wasn't a nightmare enough, the cysts got infected. my chin was scabbed, swollen, disgusting. I was so embarrassed i went home for the weekend to heal. i was given the medication on friday.. it is now sunday and my SKIN LOOKS AMAZING!! it looks even better than it did before i got the cysts. my red marks are fading, my skin looks almost perfect and it's only been 3 days. i have only been using this stuff and i cant believe the effect that it's had. this has done more for me than 3 microderms and 5 chemical peels have. i was using way too much of it at first (applying it like 3x a day) and my skin is really dry and flaky now. WHATEVER! i'd so much rather have that then the marked up mess i was dealing with before. i'm only applying it at night now. i can't wait to keep on seeing the improvements oh and i got no initial breakout!

>be 30 year old guy. Struggled with cystic acne so much and for so long that I even went off the deep end and turned my diet upside down and took Vitamin A pills like some people in the forums. Decided to break down and go to a new dermatologist though I was fearing she would give me the nuclear option: accutane. To my surprise (she was attractive), and secondly she didn't recommend accutane at all. Instead she said my cystic acne should be helped by Ziana. She also told me to wipe the silly coconut oil off my face to eat like a normal human - though I choose to avoid diary wherever possible. 2 weeks into it I could feel and see a difference. My face felt softer. I feel like almost immediately upon using that the cystic acne didn't hurt as much but disappeared at their normal slow pace. Once gone, I didn't get another one. I used to get 1 per week - and sometimes as much as 4 at a time. I would gladly pay $500 per tube of Ziana - luckily insurance prevents me paying more than $20. I love this stuff and I would brush my teeth with if it wasn't frowned upon by the warnings inside the packaging.

I've been battling adult acne for about a year and a half now. I have on and off breakouts and finally my doctor prescribed this gel. It's probably the best acne cream I've ever used. It reduces inflammation very well. It's not a MIRACLE drug, but it has noticeable effects in just a week or two. I'm still battling acne but on a much much smaller scale than a few months ago. Has kind of a sticky texture, so I put on lotion a few minutes after it dries so my skin feels nice. I would recommend this to any 20-somethings battling cystic jawline and cheek acne like I was. Also, with a rebate I got it for FREE! Even better!