Non-ablative Non-fractional Laser

What Is It?

Non-ablative lasers are less invasive but also less effective than ablative lasers. Non-ablative fractional lasers shine a focused beam of light at the skin in a fractional (dot-matrix) pattern, leaving the skin intact.

Good or Excellent Response

Strength of Evidence
12% of patients achieved a good (>50%) or excellent (>75%) improvement in scarring after 3 - 6 sessions

Moderate Response

Strength of Evidence
60% of patients achieved at least a moderate (>25%) improvement in scarring after 3 - 6 sessions
  1. Sarac, G., Kapicioglu, Y. & Cenk, H. An evaluation of the efficacy of a single-session 577 nm pro-yellow laser treatment in patients with postacne erythema and scarring. Dermatol Ther 34, e14611 (2021).
  2. Rathod, D. et al. A cross-sectional, multi-center study on treatment of facial acne scars with low-energy double-pass 1450-nm diode laser. Dermatol Ther 33, e13326 (2020).
  3. Gold, M. H., Wilson, A. & Mordon, S. R. Treatment of acne scarring with a novel dual-wavelength laser. J Cosmet Dermatol (2019) doi:10.1111/jocd.13068.
  4. Kwon, H. H. et al. Novel device-based acne treatments: comparison of a 1450-nm diode laser and microneedling radiofrequency on mild-to-moderate acne vulgaris and seborrhoea in Korean patients through a 20-week prospective, randomized, split-face study. J Eur Acad Dermatol Venereol 32, 639–644 (2018).
  5. Politi, Y., Levi, A. & Lapidoth, M. Integrated cooling-vacuum-assisted non-fractional 1540 nm erbium:glass laser is effective in treating acne scars. J Drugs Dermatol 15, 1359–1363 (2016).
  6. Badawi, A., Tome, M. A., Atteya, A., Sami, N. & Morsy, I. A. L. Retrospective analysis of non-ablative scar treatment in dark skin types using the sub-millisecond Nd:YAG 1,064 nm laser. Lasers Surg Med 43, 130–136 (2011).
  7. Asilian, A. et al. Comparison of Q-Switched 1064-nm Nd: YAG laser and fractional CO2 laser efficacies on improvement of atrophic facial acne scar. J Res Med Sci 16, 1189–1195 (2011).
  8. Min, S. U. K., Choi, Y. S., Lee, D. H., Yoon, M. Y. & Suh, D. H. Comparison of a long-pulse Nd:YAG laser and a combined 585/1,064-nm laser for the treatment of acne scars: a randomized split-face clinical study. Dermatol Surg 35, 1720–1727 (2009).
  9. Lee, D. H., Choi, Y. S., Min, S. U., Yoon, M. Y. & Suh, D. H. Comparison of a 585-nm pulsed dye laser and a 1064-nm Nd:YAG laser for the treatment of acne scars: a randomized split-face clinical study. J Am Acad Dermatol 60, 801–807 (2009).
  10. Uebelhoer, N. S., Bogle, M. A., Dover, J. S., Arndt, K. A. & Rohrer, T. E. Comparison of stacked pulses versus double-pass treatments of facial acne with a 1,450-nm laser. Dermatol Surg 33, 552–559 (2007).
  11. Keller, R., Belda Júnior, W., Valente, N. Y. S. & Rodrigues, C. J. Nonablative 1,064-nm Nd:YAG laser for treating atrophic facial acne scars: histologic and clinical analysis. Dermatol Surg 33, 1470–1476 (2007).
  12. Lipper, G. M. & Perez, M. Nonablative acne scar reduction after a series of treatments with a short-pulsed 1,064-nm neodymium:YAG laser. Dermatol Surg 32, 998–1006 (2006).
  13. Bhatia, A. C., Dover, J. S., Arndt, K. A., Stewart, B. & Alam, M. Patient satisfaction and reported long-term therapeutic efficacy associated with 1,320 nm Nd:YAG laser treatment of acne scarring and photoaging. Dermatol Surg 32, 346–352 (2006).
  14. Yaghmai, D., Garden, J. M., Bakus, A. D. & Massa, M. C. Comparison of a 1,064 nm laser and a 1,320 nm laser for the nonablative treatment of acne scars. Dermatol Surg 31, 903–909 (2005).
  15. Bellew, S. G., Lee, C., Weiss, M. A. & Weiss, R. A. Improvement of atrophic acne scars with a 1,320 nm Nd:YAG laser: retrospective study. Dermatol Surg 31, 1218–1221; discussion 1222 (2005).
  16. Tanzi, E. L. & Alster, T. S. Comparison of a 1450-nm diode laser and a 1320-nm Nd:YAG laser in the treatment of atrophic facial scars: a prospective clinical and histologic study. Dermatol Surg 30, 152–157 (2004).
  17. Sadick, N. S. & Schecter, A. K. A preliminary study of utilization of the 1320-nm Nd:YAG laser for the treatment of acne scarring. Dermatol Surg 30, 995–1000 (2004).
  18. Friedman, P. M. et al. Treatment of atrophic facial acne scars with the 1064-nm Q-switched Nd:YAG laser: six-month follow-up study. Arch Dermatol 140, 1337–1341 (2004).
  19. Chua, S.-H., Ang, P., Khoo, L. S. W. & Goh, C.-L. Nonablative 1450-nm diode laser in the treatment of facial atrophic acne scars in type IV to V Asian skin: a prospective clinical study. Dermatol Surg 30, 1287–1291 (2004).
  20. Rogachefsky, A. S., Hussain, M. & Goldberg, D. J. Atrophic and a mixed pattern of acne scars improved with a 1320-nm Nd:YAG laser. Dermatol Surg 29, 904–908 (2003).
  21. Bernstein, E. F., Ferreira, M. & Anderson, D. A pilot investigation to subjectively measure treatment effect and side-effect profile of non-ablative skin remodeling using a 532 nm, 2 ms pulse-duration laser. J Cosmet Laser Ther 3, 137–141 (2001).

Side Effects

Low-medium side effects and adverse reactions


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