Oral Antibiotic
Reviews
3.4
1734 Reviews
Oral Antibiotic
Efficacy
56%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Should never be used on its own and for a maximum of 3 months.
Oral Antibiotic
Side Effects
Medium-High
Oral Antibiotic
Acne.org’s Real World Take
Antibiotics should be used for a maximum of 3 months, provide only moderate benefit and only to some people, and may lead to side effects and strains of resistant bacteria. Studies do show doxycycline can reduce severe acne in the short term, and as far as oral antibiotics are concerned, it’s usually the go-to, but approach with caution and stay your own advocate.
Oral Antibiotic
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Doxycycline
Compare To Other Treatments
5
20.7%
4
32.9%
3
22.1%
2
12.7%
1
11.5%

Used Doxycycline? Rate It:

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September 2, 2011

Pros:

None

Cons:

Hard to take. Must be taken twice a day, without a meal, and can't be taken within 2 hours of a meal.

I took Doxy with Differin for two months. It made my acne a lot worse so my derm switched me to Mino afterwards. Both did absolutely nothing for me but make my skin worse.
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June 30, 2011

Pros:

Cheap

Cons:

Didn't clear up acne/blemishes
Pill is HUGE, almost choked on it
Made me sensitive to sun, gave me nausea

I wouldn't recommend this product, I was and still am kind of scared of accutane side effects, so my dermatologist gave me this, wasn't helpful at all
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December 1, 2010

Pros:

Cleared up acne
Helped with hyperpigmentation

Cons:

Made me really nauseated

I took 2 pills a day for my acne to jump-start the clearing process. I would take it in the day and get a lot of nausea. But it really helped me in the end and now my face looks clearer.
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September 20, 2010

Pros:

Noticeable difference within 4 days
Pretty cheap cost
Easy to take pills compared to a regimen

Cons:

Not a huge difference in amount of acne
Made my stomach hurt a couple of times
An antibiotic, not healthy for prolonged periods of time
Found better options

I took two 100mg pills a day for about 15 days and it really didn't make much of a difference, I switched to AcneFree severe and that has worked much better in just days. The pills still had me producing new acne almost every day. For a prescription I was expecting much better results. For the time that I took the pills I also seemed to be in a bad mood for a major part of the day.
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March 7, 2010

Pros:

No sign of vomiting, sore stomache etc.
No severe breakouts

Cons:

Over time loses its effectiveness

Was really looking forward using first oral treatment Four months now and it really isn't making much difference May give accutane a go
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December 16, 2009

Pros:

Works well, more convenient than slathering creams on your face almost constantly, plus you get to avoid the burning and dryness that comes with most prescription acne creams.

Cons:

Aside from the stomach-based issues that have been mentioned endlessly, after taking doxycycline for a month, I learned that yeast infections were not just the domain of women. Just saying.

Between the constantly upset stomach and the yeast infection, I decided that acne was the lesser of all evils. I stopped taking the doxycycline after the yeast infection turned up, and whenever I would take even one pill, the yeast infection would flare up and I'd have to make sure I was always within close proximity to a washroom. Plus antibiotics aren't a long term fix anyways. I, for one, don't feel all that inclined to disturbing the bacterial balances of my body indefinitely. Further along that grain, replacing a benign skin issue with one that is, ahem, less socially accepted was hardly appealing. The only thing appealing was the cost. I was prescribed Periostat to be taken multiple times daily (20mg 3x/day) and though the sticker price is $3/pill, it worked out to $10 for 90 pills once the insurance kicked in.
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December 11, 2009

Pros:

Instead of paying an estimated 20 bucks a month for brand acne medications that contains benzoyl peroxide which irritates and burns the skin, You can swallow the pill down with no worries its better then relying on topical applications!

Cons:

severe nausea, possible vomiting, mood swings, dry skin,- "so you may look a little white." hypertension, fatigue,

You must take this pill for the duration of time it tells you to on the prescription bottle unless you want the chance of vomiting, also preferably in the morning I suggest you take with food because your body is still "waking up," be cautious if your going out to tan make sure you wear sunblock some people may experience reactions while on that antibiotic, and the answer is "yes, it is ok to go tanning." for the most part I would suggest this product to anyone who is SERIOUS about completely clearing their acne. You will see the difference in about week and a half.
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November 28, 2009

Pros:

its doing its job,clearing up the acne i guess,only been taking it for about 2 days :D

Cons:

TUMMY ACHE (N) eugh pleaseplease take with food ! or you'll start to be sick.

i do recommend it,if you can't stand stomach aches don't be on this drug.
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November 7, 2009

Pros:

Dries up acne fast. Doesn't make me nautious. Used it last year, so I know it will work.

Cons:

Leaves acne scars...Makes me red.

I used to take this medicine last year when I had severeee acne. Red everywhere and huge cysts. I took this with Yaz birth control, Duac Cream, Retin A Micro, and Doxycicline. In 6 months I was completley clear. However, it started to come back this year... So i thought it was the birth control, so now I am taking Tri Lo Sprintec since Ortho was too expensive. Ive been on that for 3 weeks and I'm back to taking Doxy with all the other creams. It dries out my acne but I still get cysts... i have a bunch of horrible scars and hoping they will fade away... Don't give up guys! it takes months for some people to have it be cleared. My acne was so bad that my dermatologist had no hope.. and when it cleared he told me he was completley suprised and in shock. This is my second time going through it.. I know how you all feel but DONT GIVE UP. Its a struggle and it does cause depression but you will get through it :) Ill come back to update in 3 months
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November 5, 2009

Pros:

It is affordable for those people like me without insurance.

Cons:

It causes headaches and nausea (sometimes even taken with food). Does not work well for clearing up my acne.

I have been using this product for more than a year and I have seen very little improvement in my acne. I noticed more of an improvement by being on it than being off of it which is the only reason I continue to take it. I have no insurance and it is more affordable than other products out there so the little bit of control I get with it helps, but not by much. I still have at the very least four blemishes at any given time consistently. I would recommend another treatment if you can afford it.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.