What Is It?
Augmentation uses temporary, semi-permanent, or permanent dermal fillers that replace volume of soft tissue that is lost. All fillers also stimulate collagen production, which helps build up the skin, thus evening the skin’s surface.
Good or Excellent Response
Strength of Evidence
66% of patients achieved a good (>50%) or excellent (>75%) improvement in scarring after 1 - 4 sessions
Strength of Evidence
72% of patients achieved at least a moderate (>25%) improvement in scarring after 1 - 4 sessions
- Solomon, P., Ng, C. L., Kerzner, J. & Rival, R. Facial soft tissue augmentation with Bellafill: a review of 4 years of clinical experience in 212 patients. Plast Surg (Oakv) 29, 98–102 (2021).
- MacGillis, D. & Vinshtok, Y. High-velocity pneumatic injection of non-crosslinked hyaluronic acid for skin regeneration and scar remodeling: A retrospective analysis of 115 patients. J Cosmet Dermatol 20, 1098–1103 (2021).
- Elsamongy, M., Ayad, H., Eid, M., Gheida, S. & Latif, A. A.-. The efficacy of autologous nanofat versus enhanced nanofat with adipose-derived stem cells transfers in the treatment of atrophic post acne scars. Journal of Advances in Medicine and Medical Research 17–31 (2020) doi:10.9734/jammr/2020/v32i2430748.
- Koren, A. et al. Efficacy of a combination of diluted calcium hydroxylapatite-based filler and an energy-based device for the treatment of facial atrophic acne scars. Clin Exp Dermatol 44, e171–e176 (2019).
- Joseph, J. H. et al. Polymethylmethacrylate collagen gel-injectable dermal filler for full face atrophic acne scar correction. Dermatol Surg 45, 1558–1566 (2019).
- Dierickx, C., Larsson, M. K. & Blomster, S. Effectiveness and safety of acne scar treatment with nonanimal stabilized hyaluronic acid gel. Dermatol Surg 44 Suppl 1, S10–S18 (2018).
- Mohammad, L., Elgarhy, L. H., Saad, D. & Mostafa, W. Fractional ablative CO2 laser treatment versus scar subcision and autologous fat transfer in the treatment of atrophic acne scars: New technique. Journal of Surgical Dermatology 1, 29–36 (2016).
- Goodman, G. J. & Van Den Broek, A. The modified tower vertical filler technique for the treatment of post-acne scarring. Australas J Dermatol 57, 19–23 (2016).
- Sarkate, A., Ghate, S. & Dhurat, R. Split-face placebo-controlled study to evaluate the efficacy of type A botulinum toxin in postacne facial scars. British Journal of Dermatology 173, 21–76 (2015).
- Sapra, S., Stewart, J. A., Mraud, K. & Schupp, R. A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring. Dermatol Surg 41, 587–594 (2015).
- Karnik, J. et al. A double-blind, randomized, multicenter, controlled trial of suspended polymethylmethacrylate microspheres for the correction of atrophic facial acne scars. J Am Acad Dermatol 71, 77–83 (2014).
- Munavalli, G. S., Smith, S., Maslowski, J. M. & Weiss, R. A. Successful treatment of depressed, distensible acne scars using autologous fibroblasts: a multi-site, prospective, double blind, placebo-controlled clinical trial. Dermatol Surg 39, 1226–1236 (2013).
- Solomon, P., Sklar, M. & Zener, R. Facial soft tissue augmentation with Artecoll(®): a review of eight years of clinical experience in 153 patients. Can J Plast Surg 20, 28–32 (2012).
- Sage, R. J. et al. Subcuticular incision versus naturally sourced porcine collagen filler for acne scars: a randomized split-face comparison. Dermatol Surg 37, 426–431 (2011).
- Epstein, R. E. & Spencer, J. M. Correction of atrophic scars with artefill: an open-label pilot study. J Drugs Dermatol 9, 1062–1064 (2010).
- Beer, K. A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella. Dermatol Surg 33 Suppl 2, S159-167 (2007).
- Varnavides, C. K., Forster, R. A. & Cunliffe, W. J. The role of bovine collagen in the treatment of acne scars. Br J Dermatol 116, 199–206 (1987).
- Stegman, S. J. & Tromovitch, T. A. Implantation of collagen for depressed scars. J Dermatol Surg Oncol 6, 450–453 (1980).
Medium side effects and adverse reactions