Topical Retinoid
Reviews
3.2
1910 Reviews
Topical Retinoid
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Prescription and over-the-counter adapalene share the same efficacy percentage due to non-specific research, but prescription strength likely performs better.
Topical Retinoid
Side Effects
Low
Topical Retinoid
Acne.org’s Real World Take
This topical retinoid medication provides partial relief at higher prescription dosages, but don’t look for complete clearing, especially at over-the-counter strength. Relatively affordable and comes with less side effects than tretinoin, the other affordable topical retinoid. As a bonus, it improves the look of skin and reduces fine lines and wrinkles a bit too.
Topical Retinoid
How to Get It
This is an over-the-counter treatment. Here are some places you can find it online.
Read All About Adapalene (Non-prescription)
Compare To Other Treatments
5
17.5%
4
30.4%
3
22.6%
2
17.1%
1
12.4%

Used Adapalene (Non-prescription)? Rate It:

Choose from 1 to 5 stars
March 2, 2010

Pros:

.1% cream:
Reduced existing acne
- Helps prevent flare-ups
- Helps papules & scars disappear quicker
- Fragrance free
- Best Differin option for sensitive skin
- One tube goes a long way

Cons:

- Causes irritation if I use it more than 1x/2days
- Acne has not gone away completely
- Skin is very sensitive to sunlight
- Expensive if you don't have insurance
--> $220-$250 for a 45g tube, that should last 6 months if you apply 1x/2days

After nearly a year of treatment (5 months with Differin), my acne is light and tolerable. At age 21 my my light/moderate face acne worsened and I developed moderate and embarrassing (large papules) back and chest acne. After a year of benzoyl peroxide and salicylic acid OTC treatments, I went to a dermatologist who put me on Minocycline (and Differin, but it took me 5months to finally purchase Differin bc its extremely expensive and I don't have insurance-- bad move though bc it could have helped speed up the process from the beginning). I began noticing results from Minocycline after 2 months, and by month 5 my back acne reduced to maybe 5 zits a week and face acne was back to light/moderate. Then (at 5 months) I began taking Differin too. Now, at 10 months (5 months of Differin) my face has light acne (no big papules any more; still have small bumps a few times a week and blackheads on nose and forehead) and maybe only one or two zits a month on my back. The scarring is starting to clear up a bit too from the Differin. I'm happy with my results and may actually be able to wear tank tops this summer, but my acne has not entirely disappeared. One 45g tube of Differin .1% cream without insurance cost me $250, but lasts about 6 months. (( If I use Acnomel as a spot treatment after applying Differin, the two combined helps dry up the bigger zits quicker, usually gone or minimal in 1-2 days )).
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December 17, 2009

Pros:

Cleared up all acne
made red marks fade faster
no scent

Cons:

zero.

So this is how differin worked for me. I was hesitant to try it at first after reading all the reviews about how it destroyed the faces of so many. I had moderate acne with cysts, blackheads, whiteheads, you name it. So I started on Duac and used it both at night and in the morning. This cleared most if not all of my acne up within two months. About a year later I began to get more and more clogged pores and whiteheads, so I decided what the hell i might as well try it. The first week it brought out an extra maybe four or five little red bumps which dissapeared within three days, after that I haven't had a single zit and it's four months later. The bottom line is try it. It worked wonders for me so it might for you as well.
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December 3, 2009

Pros:

DIdnt do anything but it didnt hurt me

Cons:

Didnt do anything I even used the largest % they had and still NOTHING.

I dont know why but this had no effect on me.
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November 23, 2009

Pros:

Cleared up my Acne, easy to use, does not dry out my face

Cons:

Occasionaly still have breakout, but probably due to hormones.

Would definetly recommend to anyone who has had trouble with acne. I started using Differin while I was taking Minocycline and slowly went off the Minocycline and never broke out, which was a miracle.
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November 18, 2009

Pros:

Needless to say, my acne and overall skin condition has improved dramatically. No inital breakout AS OF YET. My fingers are crossed

Cons:

By using a pea sized amount, no cons to report. Does not necessarily help cure pustules.

DO NOT USE THIS IN LARGE AMOUNTS. For all who are complainning that it burns or stings, your using too much. 4 pea sized amounts is all you will need. I recommend this drug.
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October 25, 2009

Pros:

it made my skin very soft and clear.

Cons:

it made my skin very dry at first and actually burned my face really bad due to puting way to much on. so be light on the amount.

it works! i would love to have more but i cant afford it right now
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October 1, 2009

Pros:

Acne Vulgaris under control

Cons:

Intial flare up of acne at the begginning.It gets worse first and then slowly the acne disappears.
I am bown skin.So my face looked terrible with the peeling and subsequent tanning.

It works well with acne. But on brown skin , you need to avoid sun (flouroscent indoor lighting) completely.My scars were very visible while I was using it. I used it for 3 months and stopped because my scars were getting worse.
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June 17, 2009

Pros:

This product is awesome... had been trying various products for the past eight years and my acne just didn't settle...But after using this product for the past three months my skin has cleared ur tremendously! I recommend it to everyone.

Cons:

Makes skin dry, but its not anything a moisturizer cant fix!

Use it!
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June 8, 2009

Pros:

Actually works but it takes so long for it to take effect

Cons:

God it takes forever to see results

May very well be worth it because it actually works for being so expensive
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May 23, 2009

Pros:

it worked

Cons:

takes sort of a long time

I broke out in the beginning, but it did eventually get better. I found something that works. not breaking out like before, and WAY better skin.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.