Topical Retinoid
Reviews
3.2
1910 Reviews
Topical Retinoid
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Prescription and over-the-counter adapalene share the same efficacy percentage due to non-specific research, but prescription strength likely performs better.
Topical Retinoid
Side Effects
Low
Topical Retinoid
Acne.org’s Real World Take
This topical retinoid medication provides partial relief at higher prescription dosages, but don’t look for complete clearing, especially at over-the-counter strength. Relatively affordable and comes with less side effects than tretinoin, the other affordable topical retinoid. As a bonus, it improves the look of skin and reduces fine lines and wrinkles a bit too.
Topical Retinoid
How to Get It
This is an over-the-counter treatment. Here are some places you can find it online.
Read All About Adapalene (Non-prescription)
Compare To Other Treatments
5
17.5%
4
30.4%
3
22.6%
2
17.1%
1
12.4%

Used Adapalene (Non-prescription)? Rate It:

Choose from 1 to 5 stars
January 7, 2007

Pros:

uhhh

Cons:

uhhh

question: does this really help with spot scars? and does it cause them? i noticed when i used this that the old spot scars SORT of faded away, but then after i get new pimples (and they turn into huge whiteheads because of the differin) when they finally heal they just turn into spots...and i do not want any of those...someone please answer
January 5, 2007

Pros:

My skin does seem clearer, though not perfect. After years and years of bad skin, "clearer", for me, means, "better."

Cons:

A little dry and itchy at first, but get a good moisturizer during the day to counteract it.

It's not a miracle medication, but it helps.
November 24, 2006

Pros:

Very good results

Cons:

dry skin, reallly itchy, red spots acne a bit worse horrible for the first week

Take it for more then a week and your will see great results, give it a chance
October 5, 2006

Pros:

HealthNet covers it as a medicine not a cosmetic - otherwise it is $100 a tube or so out here.

Cons:

No measurable improvement after 9 months.

I'm in my 30's, mixed race with olive skin. I don't have "pimple" acne, mostly blackheads, blocked pores, etc. I don't use makeup. After using Differin for several months, I got scaly, red almost painful hive-like lesions on my chin and the skin around my hairline got bumpy and the skin peeled and now I have more scars. In the months prior to this nightmare, my skin was as oily and blotchy as when I started. My skin is so dry now that even with lotion, skin flakes and lifting scabs are visible. My doctors didn't even tell me the "worse before better" line, they just keep telling me to use it. I just got a prescription for topical Clyndomiacin today since I have so many raw patches - I don't scratch, the skin rubs off - and will use that while I look for another dermatologist. It is impossible to think that this is the only and best acne medicine out there.
January 1, 2012

Pros:

None, really

Cons:

Didn't clear up acne

I've been using this for 4.5 months, with no real noticeable results. Unlike many, I didn't really experience a noticeable IB - however it hasn't reallly worked either. I may give it a little more time, but at 5-6 months will be quitting. You get a lot of medicine per tube, though, so I don't view it as being prohibitively expensive. I'm on my first (and only) tube so far.
September 6, 2011

Pros:

Doesn't make your skin worse

Cons:

You have to avoid sunlight
You can only use peasize amounts when putting it on your skin
No change in acne

Didn't work for me. Used it for 6 weeks.
December 10, 2009

Pros:

none

Cons:

I went to the dermatologist for my acne and he gave me a little sample tube of differin 0.3. My skin became dry and peely after a couple of days...

My skin became very very dry and was flaking off. Even made me have big red splotches on my face... used it for about 2 weeks but i couldn't stand it anymore! Went back to the dermatologist and he gave me Retin-A. Been using that for about a week and my skin is much better! :)
October 31, 2009

Pros:

None

Cons:

same sh*t

I'm starting to think that there is no such thing as an acne treatment. I have tried everything and nothing works. Most acne 'Treatments' are commercial shills, thought up by evil f**k bag salesman, that don't have a clue what we're going through. They don't understand how much acne hurts our mental state. They don't care what we feel, they're in it for the money and that's it. The only thing I recommend is, stop eating sugar and dairy products. That helped me.
October 19, 2009

Pros:

none

Cons:

burning skin, redness, it doesn't work

the worst product I've used, i used this stuff for long time but never worked for me, produce redness and irritation, burns my skin, and never saw good results, this stuff sucks
September 15, 2009

Pros:

Its available nearly all over the world. The price is relatively cheap in
this country. The gel is easy to use.

Cons:

After about 3 days it may peel off. If applied everyday it may peel or acne may flare up.

After 1 year of suffering acne, I was introduced to this infamous dermatologist in my hometown Korea. I received a 1:1 consulting and I asked some questions. After the doctor looked at my skin, she prescribed me Differin. I applied it for two days straight and my skin started to peel! I thought I should just use it once per two/three days.. Till now its working out for me but I would recommend this to people who actually received a prescription from a dermatologist. Everyone has different skins so nooone can tell you whats good for your skin unless they actually see it and know something about different types of skin and acne. I live in Dubai, UAE

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.