Topical Retinoid
Reviews
3.2
1910 Reviews
Topical Retinoid
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Prescription and over-the-counter adapalene share the same efficacy percentage due to non-specific research, but prescription strength likely performs better.
Topical Retinoid
Side Effects
Low
Topical Retinoid
Acne.org’s Real World Take
This topical retinoid medication provides partial relief at higher prescription dosages, but don’t look for complete clearing, especially at over-the-counter strength. Relatively affordable and comes with less side effects than tretinoin, the other affordable topical retinoid. As a bonus, it improves the look of skin and reduces fine lines and wrinkles a bit too.
Topical Retinoid
How to Get It
This is an over-the-counter treatment. Here are some places you can find it online.
Read All About Adapalene (Non-prescription)
Compare To Other Treatments
5
17.5%
4
30.4%
3
22.6%
2
17.1%
1
12.4%

Used Adapalene (Non-prescription)? Rate It:

Choose from 1 to 5 stars
December 24, 2007

Pros:

i dont think theyre are any

Cons:

my face is red, and peeling, and swollen, and my acne is wayyy worse than before.

I've only used this for two months, and i know its supposed to get better before it gets worse, but this bad?? i dont think its worth it. i guess i'll keep using it, but im not expecting anything to come of it. dont buy this
December 21, 2007

Pros:

skin cleared up after few months, it takes a while to work, but i used to have a severe case of acne or 5 years, but now they are all gone!

Cons:

my skin got dried and irritated especially over the winter time. When it was the most severe, it was red, rashes visible, swollen, chapping and peeling, stinging and burning...

it works if you give it a few month to do its thing, but if you have a sensitive skin like mine, it does other damages such as drying and peeling.... but these side effects seem to get better after a while
December 14, 2007

Pros:

Didn't have a strong or undesirable smell

Cons:

IMMENSELY DRYING, Causes Flakiness/Redness, Stinging Feeling Throughout the day

Even though some of my acne 'cleared up', my skin hurts so much. I do not recommend this product for anyone... especially with dry skin. My skin feels and resembles chapped lips. It's horrible and very painful.
October 6, 2007

Pros:

Well it worked for the first 6 mothns the last 6 it hasnt been doing sh*t. Im switching to proactive

DOSENT WORK IN LONG LONG TERM
September 8, 2007

Pros:

helps clear up exsisting pimples and prevents new ones from forming, closes open pores,no more whiteheads forming, prevents wrinkles, gets rid of some red marks left by acne,

Cons:

skin feels raw, bad breakouts, tightness feeling, which is also associated with dry skin, peeling, redness but usually goes away after two months of CONTINUAL usage.

I believe that Differin works. The thing is you have to use it continually cause if you miss a day your skin may breakout and you will be at point one again. You have to put it ALL over your face NOT just on the zits.PUT DIFFERIN ALL OVER YOUR FACE,besides the mucous membranes!! this is very important for differin to work. The way i used differin is i applyed a thin film(layer) for the first weeks then build up each month to a little thicker layer. Also on the package it says NOT to put on the corners of the nose( the part on the sides of the nostrils) Personally i put it there because i build a tolerance to differin, some peoples skin in that area may be sensitive, so try to avoid that area if that is you. This is not approved by the FDA, but my dermatologist said it may prevent and get rid of wrinkles on skin, because it is similar to a r-tena(forgot how to spell it). I wouldn'tknow if it cleared up wrinkles because im only seventeen.
August 4, 2007

Pros:

Dramatically cleared my skin within one week and it just kept getting better, 2 months later, I looked great

Cons:

When I first started I had a small dry patch along my jaw line, later the dry patches got worse and pretty soon all around my chin and mouth were all scaly and flaky, it was gross.

I have moderate to servere acne and I was first put on clindamycin phospate (AM), minocycline(1oo mg) and differin (PM. Everything seemed to be working and I felt great but then when my skin started to get really dry my dermatologist took me off differin and I started to break out a lot. So a couple months later, she put me back on differin and my skin burned, itched, and was really red and scaly. It didn't improve my skin at all and now I look terrible. It may work for you if you don't have sensitive or dry skin, but if your skin it sensitive at all, be carefull!
July 30, 2007

Pros:

Helped in treating my minor breakouts and temporarily haulted breakouts all together.

Cons:

dry itchy skin, reacted with almost all lotions i used. Left my skin feeling like it was on fire

For the price of this product, it may be useful to some. But for me it had little affect in my cystic acne.
May 29, 2007

Pros:

easy to use. cheap-ish. doesn't ruin your clothes.

Cons:

it has made the problem worse...still waiting for when it all gets better.

I am 31 and starting to get wrinkles but the acne has come back in force which is a cruel irony. I had used the contraceptives Brenda and Diana in my 20s which were fantastic but affected my libido so badly, it almost cost me my marriage. I promised not to go there again so my doctor prescribed differin which has made the problem so bad, I am almost embarrassed to go out. I am waiting for it to 'get better' as it is meant to take 8 weeks or so to show an improvement. But I am tempted to go the hard stuff and get a course of roaccuatane which I used in my teens and was fantastic.
January 11, 2007

Pros:

Seems to work well

Cons:

Very dry skin

Ive been using this for just over a week with erythromycin, it seems to work better than any other thing ive tried including just erythromycin, benzyl peroxide, and shop brought stuff, im hoping that using a moisturiser will improve things. It must be alot cheaper in england as it is only about £7 per tube.
January 9, 2007

Pros:

Covered by insurance after prior authorization from MD. Easy to use.

Cons:

If have to pay out of pocket...horribly expensive. Worked ok at first. Dried out skin around my eyes even though not applied there.

not worth it for this 36 year old acne sufferer for 25 yrs! Have Tried EVERYTHING! over the counter and RX. except Proactive, which is next.

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.