Topical Retinoid / Topical Antibacterial
Reviews
3.7
579 Reviews
Topical Retinoid / Topical Antibacterial
Efficacy
67%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid / Topical Antibacterial
Side Effects
Low-Medium
Topical Retinoid / Topical Antibacterial
Acne.org’s Real World Take
A way of using benzoyl peroxide in combination with the topical retinoid, adapalene, that studies show works a bit better than benzoyl peroxide alone. Comes with side effects for the first weeks and can bleach fabric. Note: When used correctly, benzoyl peroxide on its own can completely clear the skin.
Topical Retinoid / Topical Antibacterial
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Adapalene / Benzoyl Peroxide (Epiduo®)
Compare To Other Treatments
5
38.2%
4
27.3%
3
11.1%
2
8.6%
1
14.9%

Used Adapalene / Benzoyl Peroxide (Epiduo®)? Rate It:

Choose from 1 to 5 stars
June 29, 2010

Pros:

Heals acne fast.
Helps fight bacteria (Benzoyl Peroxide)
Helps with spots.

Cons:

Makes your skin dry, so only use it where you need it.

I have been using Differin for about a year and a half, along with Tetracycline. The Differin was okay, it made my skin heal faster, but it wasn't doing anything to help with the bacteria that was contributing to the acne in the first place. So about a month ago my doctor told me to start using Epiduo. He also told me to take the Tetracycline more frequently (2 in the am and 2 in the pm) I was really surprised at how fast it cleared my breakouts. My skin breaks out because of my hormones, so I can't do much to prevent the acne ( I still get a few pimples here and there) but they are small and are gone within a day, thanks to Epiduo. I never had the "purging" effect either, probably because I was already using Differin, and my skin had already been purged with an increase in breakouts. But I'm glad I went through it because now my skin is so much better. It took a while to figure out what my skin needed. And I learned what irritates it and what helps it. Be smart when you try products to help your skin, a little goes a long way. I also found that eating right, drinking lots of water and exercising helps too. I ONLY drink water and I make sure to eat plenty of vegetables. I also run every morning I get (nothing too extreme). Sometimes you can't just sit back and expect a little cream to do everything for you. Take care of your body, inside and out, and you will be beautiful :)
This Was Helpful

15 user(s) found this helpful

Report
June 29, 2010

Pros:

Clears Acne

Cons:

stings

I've tried EVERYTHING to clear my acne. I had taken antibiotics for a month and endured stomach problems (and the acne still didn't go away). This stuff actually works! Right away my acne cleared up. The stinging of the gel (for the first 15 minutes or so) is definitely worth having clear skin for a change! Especially since I'm 43 and really shouldn't have acne!!!
This Was Helpful

19 user(s) found this helpful

Report
June 29, 2010

Pros:

-helped reduce the size of the acne
-toned the redness
-helps prevent new acne

Cons:

-if not used properly it will dry/burn skin

I've had acne severely for the past 3 years and nothing I have tried has helped. I've been to the dermatologist quite a few times, she wanted to put me on accutane but my mother read reviews and well... that's just not going to happen. So she gave me these samples of epiduo(so I could see if it worked before we paid $200.00 for it) that I have been using for the past 3 weeks every night and I have seen a big difference in my skin. It's slowly but surely going away it's just taking its sweet time. Hope this helped!
This Was Helpful

28 user(s) found this helpful

Report
June 18, 2010

Pros:

-It's a product made with two products that are considered the best in the treatment of acne.
-Your acne really go away.
-Skin without spots.

Cons:

-Skin a little bit dry.
-You can't go out without sun block, because you can have burns.

My skin was terrible. I didn't know what to do. So, I decided to go to my dermatologist and see what I can do to improve my skin. When I buy this product and I started to use, I can saw clearly an improvement in my skin. I bought make products without oil too, because we have to use products to our tipe of skin, and skin with acne problems usually are oily. I really recommend this. My skin know is pretty good and I improve my self steem again.
This Was Helpful

12 user(s) found this helpful

Report
June 12, 2010

Pros:

Got rid of almost all pimples
Got rid of red acne marks

Cons:

Made skin pretty dry
Pretty expensive (There is a coupon online...use it!!)

This product has saved my life. Before this product my skin was breaking out like crazy, I had bumps on my skin and pimples on my face and tons of old acne scars. I started using this product every night and noticed results immediately. My skin got pretty dry, so you MUST have a good moisturizer, a gentle cleanser, and a face exfoliator. (I use oil of olay sensitive skin moisturizer, cetaphil or oil of olay cleanser, and Dr. Denese Microdemabrasion scrub) I have tried everything from plain old benzoyl soap, spot treatments, zeno, clydimiacin in pill and topical form and NONE have worked the way this has. It has been a miracle for me..I realized it is pretty pricey for such a small tube but think how much you will save on other acne products..just get one that works! I never write reviews on sites, but this product has astonished me to the point that I have to write one. Your skin will get pretty dry with this product so sometimes what I will do is use it at night for two nights in a row and apply moisturizer in the morning, and then on the third night do not apply the epiduo and put aloe vera gel on my face (I use banana boat...even though it has a fragrance and alcohol in it it works better for me than the pure one)..Hope I have helped any of you thinking of trying it!
This Was Helpful

17 user(s) found this helpful

Report
June 7, 2010

Pros:

helps with post acne marks
helps get rid of all the dirt built up in pores
doesn't bleach clothes, sheets, etc

Cons:

makes skin really sensative to sun
makes you breakout like crazy in the beginning
slow moving process...

so when going to the dermatologist she told me it would be a slow moving process, that it will take time to see results. i didn't really believe her, but shes definitely right! it makes you break out like crazy a few weeks into it and skin is a little red. i had a horrible month where i had huge pimples and i was constantly breaking out. that was really discouraging, but the doctor said thats normal. the medicine is designed to get all the dirt thats built up and surface it.... basically you break out until you can't anymore. i started my treatment in february, and by april my pimples were much smaller, less red, and fewer with every breakout. as time went on it got less and less. and now i hardly have a pimple. every now and then i'll have a small one, but definitely worth it in the end! i have a few post acne marks now, but the cream also helps fade the hyper pigmentation. figured i'd share my experience with it because i know how frustrating it can be, but seriously stick with it. the ending result is so worth it :-)
This Was Helpful

25 user(s) found this helpful

Report
May 29, 2010

Pros:

Easy to use cream, almost gel like.
Keeps my skin CLEAR
No new blemishes!!

Cons:

A little drying at first, fixed that with Cerave lotion
I cant put moisturizer immediatley on after, it burns

Easy to use, apply pea sized amount to each area (nose, chin forehead, ect...) after washing. It is drying, so use a moisturizer! But it can burn if applied directly after, so I put moisturizer on in the mornings, this stuff on at night. This AND bc pills and Bactrim has kept me spot free since I started so I cant say which is doing the most work, but its great! I put severity as light since i dont have acne anymore! LOVE IT. Free so far with my samples, but I'm filling my prescription next week. Hope its not too pricey!
This Was Helpful

4 user(s) found this helpful

Report
May 27, 2010

Pros:

None yet

Cons:

Dries skin out
Stings really bad especially if you put on moisturizer

I've been using this product for about 3 weeks now and I haven't seen any results yet. Right now all it does is just dry my skin out and it my face sting really bad! I can't even put anything on it cause it'll make it worse. I also take 100mg minocycline as an antibiotic 2x a day and I use Cetaphil face wash. Being on this pill has reduced the redness and pain of my pimples so that's the only Pro to my treatment right now. So far Epiduo isn't doing anything I just hope it kicks in soon.
This Was Helpful

3 user(s) found this helpful

Report
May 20, 2010

Pros:

- I guess keeps skin in check for a little bit

Cons:

-Did nothing for me
-Skin probably got WORSE

I used this after I came off accutane and started breaking out again. has really done nothing for my skin, and I think my skin is ACTUALLY WORSE! Not for me I guess...
This Was Helpful

15 user(s) found this helpful

Report
May 20, 2010

Pros:

-Absorbs Quickly
-No Odor/Smell
-Helps Blemishes
-Doesn't Stain(although they told me it would)

Cons:

-Dries Skin Out(Beware)
-Stinging

I was prescribed this to take with my Accutane.I've been using this for about a month.My skin is sensitive,so I only use it every other night cause it dries skin out.I recommend moisturizing every other night and every morning,cause it is drying,and this is coming from someone with very oily skin.I mainly use it along my jawline because that's where I get cystic acne,and it has helped,I have broken out,but not as bad and it dries up my breakouts and has definitely helped my blemishes lighten.I recommend it,just moisturize!
This Was Helpful

17 user(s) found this helpful

Report

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.