Topical Retinoid / Topical Antibacterial
Reviews
3.7
579 Reviews
Topical Retinoid / Topical Antibacterial
Efficacy
67%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid / Topical Antibacterial
Side Effects
Low-Medium
Topical Retinoid / Topical Antibacterial
Acne.org’s Real World Take
A way of using benzoyl peroxide in combination with the topical retinoid, adapalene, that studies show works a bit better than benzoyl peroxide alone. Comes with side effects for the first weeks and can bleach fabric. Note: When used correctly, benzoyl peroxide on its own can completely clear the skin.
Topical Retinoid / Topical Antibacterial
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Adapalene / Benzoyl Peroxide (Epiduo®)
Compare To Other Treatments
5
38.2%
4
27.3%
3
11.1%
2
8.6%
1
14.9%

Used Adapalene / Benzoyl Peroxide (Epiduo®)? Rate It:

Choose from 1 to 5 stars
July 26, 2011

Pros:

Calms redness really well. Not too drying. Has gotten rid of lots of blackheads.

Cons:

Takes at least 2-3 months before it starts to show improvement - can have nasty breakouts and blackheads galore to start with.

I definitely recommend Epiduo cream. It's not too harsh or drying for the skin and your skin gets used to the BP really quickly. Initially there was a bad breakout and heaps of blackheads came out, but after three months the skin seemed to calm down and most of the blackheads have gone. Give it a go but give it time to work.
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May 6, 2011

Pros:

Haven't seen any

Cons:

None

Bottom line is I am reading these reviews & I have not experienced any of the mentioned pros or for tht matter Cons. In fact my skin is slightly worse. I HAD Light acne & this product has seemed to make it worse. I've been using it for 6 weeks and nothing to report.... perhaps the makers of this product are writing the good reviews lol I will stick with it for another 4 weeks???? We'll see!!
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July 1, 2010

Pros:

clears acne
prevents intense breakouts

Cons:

dries skin out
burns at times

Epiduo has really helped me. My skin looks amazing. I still kind of break out a bit, but that is to be expected. Also, the burning can be unbearable at times, but to wake up to clear skin makes it worth it. USE moisturizer. The dry skin is another reason why the Epiduo burns at times. I am on my third week and i see huge progress. I am also still learning, so hopefully the side effects will get better.
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November 28, 2009

Pros:

Cleared up my acne.. after about 2 months of use

Cons:

Burns, made my skin peel nightly, made me break out

When I first started using this, it made my skin break out worse than I have ever seen; after that, it was just a battle to get it back to how it was originally. Epiduo made my skin burn and peel, but it also managed to remain oily.
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October 24, 2009

Pros:

cleared up skin entirely in about 2 weeks.

Cons:

dry skin at first, went away later

if paired with a moisturizer right before application of epiduo, then results are great and dry skin is less severe
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September 1, 2023
Product used:
Didn't work well and never healed completely
It never completely healed my acne even if my lifestyle was good. However, my acne got worse and i had to take antibiotics(tetracicline) and then i switched to trifarotene. I didn't experience any side effects with Epiduo.
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December 9, 2019
after 20 years I have clear skin!

Im 34 and have had acne for at least 20 years. Ive tried many things including birth control pills, salicylic acid, oil cleansing regimens, benzoyl peroxide, essential oil blends, just all kinds of stuff. I settled on the acne.org regimen with the benzoyl peroxide, and that was the most helpful thing, it kept my acne fairly low but I would still have a zit or two at least at all times as well as many small blackheads and white heads. sometimes it would become very bad, such as it did this past summer when I was almost embarassed to show my face in public. it was bumpy and had sore spots.

I started this medication in July 2019, and my face has gradually gotten better and better, my breakouts less severe. At this point in early December, I have no active zits at all! my skin feels smooth when i run my fingers over it to wash it, and my old spots are healing and lightening. Im so excited that finally I get to have clear skin. I dont know why my skin never got better after my teen years, but Im glad Ive finally found a solution.

It's important to note that I didnt see a significant improvement for about 3-4 months. Also I have very light skin, I see some darker skinned people have had trouble with bleaching, but this isnt an issue for my skin tone.

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April 9, 2019
um ?

this product bleached my face. no joke. 

just because it didn't work for me, does not mean it wont for everyone BUT if you are a darker skinned person (like myself) be wary of the product's bleaching nature. 

sayonara 

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February 25, 2019
Very painful process but worth it

I?ve had adult acne since I was 20 (now 37). I got it under control for years by being on birth control but 4 years ago it came back with a vengeance. My problem has mostly been closed comedones from the cheeks down and jawline. For the last 4 years my doctor and I have tried everything. Different types of birth control, antibiotics, retinol. Nothing worked and my skin would still be bumpy. I got desperate and tried sebaceous gland ablation. This treatment was painful, expensive  and left me scarred. Plus the products they made me use contained ammonium laureyl sulfate which I have only now learnt is a trigger for acne. After two months of ?treatment? my skin was worse than ever. I switched back to my ASAP products which helped a bit but the bumps remained. Given that my acne is hormonal, I decided to try a female doctor. She told me she had suffered with acne herself and epiduo had really worked for her. I was skeptical that a cream could really do anything for my damaged skin but decided to give it a try since her skin was clear. 

First week, less pimples. Skin became dry and scaley.

Second week, skin was terrible. I woke up every morning with 5 inflamed pimples and another 5 would develop through out the day. My skin would burn when I applied the cream. So I stopped using a salicylic acid toner and skin clearing gel with glycolic acid in it. This reduced the burning. However the pimples were so painful that my face was swollen. The glands in my neck even became inflamed because of the acne. At this point I contemplated going on antibiotics but didn?t. 

Third week, skin was less dry and scaley but I was starting to wake up with less pimples. Then one day all the bumps on my chin area and jaw line became huge inflamed pimples. 

Fourth week (now), suddenly I?ve realised that my skin is smoother than it?s been in four years. What the epiduo did is bring every single closed comedone to the surface. And it?s stopped new ones from forming. My skin is pretty much clear now except for red marks. I?m applying aloe Vera gel to the marks to help them fade. I?m hoping I?m on the road to recovery now.

Morning routine: ASAP Daily Facial Cleanser, the Ordinary Zinc and Niacinamide serum mixed with Vitamin C suspension serum, oil free moisturer with SPF.

Night routine: double cleanse with ASAP Daily Facial Cleanser, epiduo, oil free moisturiser. After LED light therapy I apply Aloe Vera Gel to the marks and any healing blemishes. 

Twice per week, after cleansing, I also use a microdermabrasion scrub.

Before and after photos below 

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March 5, 2019

Hi congratulation to your success ! I have a same situation about your skin problem too , my question is how do you apply the product? Is it only on the affected area?

March 5, 2019

Beautiful! I'm so happy for you!

December 21, 2017
IT WORKS!!!
So this is the only treatment that worked for me 100%.It is true,the first 3 months are definitely hard,but I can say,worth the effort.After 5 months of using Epiduo,I HAD NO ACNE,it heals even the marks in the skin.HIGHLY RECOMMENDED!
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February 18, 2018
Hello,
February 18, 2018
Hello, are it still using epiduo and does it continue to work for you?

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.