Topical Retinoid / Topical Antibacterial
Reviews
3.7
579 Reviews
Topical Retinoid / Topical Antibacterial
Efficacy
67%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid / Topical Antibacterial
Side Effects
Low-Medium
Topical Retinoid / Topical Antibacterial
Acne.org’s Real World Take
A way of using benzoyl peroxide in combination with the topical retinoid, adapalene, that studies show works a bit better than benzoyl peroxide alone. Comes with side effects for the first weeks and can bleach fabric. Note: When used correctly, benzoyl peroxide on its own can completely clear the skin.
Topical Retinoid / Topical Antibacterial
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Adapalene / Benzoyl Peroxide (Epiduo®)
Compare To Other Treatments
5
38.2%
4
27.3%
3
11.1%
2
8.6%
1
14.9%

Used Adapalene / Benzoyl Peroxide (Epiduo®)? Rate It:

Choose from 1 to 5 stars
April 3, 2012

Pros:

Does clear up pimples.
You can get a pimple gone in approximately 3 days.
Works great with oily skin.
Gets rid of blackheads.

Cons:

DRYNESS!
Redness
Scaling and peeling skin
Makes you look like you have chemical burns
Makes your face very tight
Sunlight makes it worse

I have been using Epiduo exactly a year from today. I am a 16 year old male. Overall, the medication is great at getting rid of acne. When I started a year ago, (with moderate acne), it took about 2 weeks to fully clear up. This is a drug you have to be patient with until your skin gets the hang of it. With this medication comes a lot of irritating problems.. If I put it ALL over my face, I never have a breakout. But the thing is, my face gets EXTREMELY dry-- Almost to the point to where I can't even move my face and show facial expressions. If I attempt to smile or laugh, my face gets all cracked and looks horrible. My (now previous) dermatologist suggested for me to use spot treatment, but I have done that and it just makes my acne area look bigger and I have breakouts where ever I'm not putting it on. The dryness isn't such a problem around my forehead, but if you put it anywhere around your mouth, nose, or chin, expect the hideous cracking to take place. I just got back home from a new dermatologist (because my last one was continuing to prescribe me Epiduo, although I have stated I wanted something new), but my new dermatologist has prescribed me SOLODYN and Duac topical gel. I'm hoping it has better affects than Epiduo.
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April 2, 2012

Pros:

Less breakouts
Helps cystic acne

Cons:

Dryness
Only used at night
Doesn't help scarring or redness

Epiduo works and even helps with cystic acne. I had small cyst 6 days ago and within 2 days, it formed the cyst into a head. I've only had 3 cysts thus far and the other two I used the cortisone shot. My dermatologist prescribed Epiduo and Doxyciclene. I know that Epiduo has helped with preventing breakouts but it hasn't helped with scarring or redness. I hope I can get to the point that I don't need to wear foundation.
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April 2, 2012

Pros:

-Clears Acne
-Works Fast
-Reduces Hyper pigmentation

Cons:

-Dries Skin
-Initial Breakout

My dermatologist gave me a prescription for epiduo about four months ago. I was skeptical because I had tried it before (for about 2 weeks) and it did nothing, but I decided to stick with it the second time around. At first it started clearing up my skin, although it was a bit drying, then came the initial breakout. My face looked horrible! But I kept using it faithfully every night. After about a month and a half my skin started clearing up beautifully. Now after 4 months my skin is about 98% clear (I still break out around that time of the month) and my face is sooo smooth (thanks to honey masks). I would definitely recommend giving this a shot and sticking with it!
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March 29, 2012

Pros:

Hasn't dried out my skin.
Seems to work.

Cons:

Burns my face a little when I put it on at night.
Caused extra acne on my face (i guess that's it just cleaning my face out).
Veerrryy expensive!!

I've only been using epiduo for 3 days now. My doctor prescribed it with clindomycin. I put a thin layer of both of them on at night. So far, i haven't seen much of a change. I have noticed just a few more bumps on my face, but nothing major. When reading these reviews before I started using it, I was scaredto even try it because I didn't want to have the 'major breakout' that most people say you have at the beginning. But I decided to try it while I'm on my spring break so that maybe the breakout would only last the week that I'm on spring break. But anyways, I Am sooo glad that Im not having the initial breakout, knock on wood, and I feel lie this is going to work for me! I hope so.
March 22, 2012

Pros:

Cleared up my back acne
Made my back softer
Got rid of scars on my back

Cons:

None

I use Epiduo on my shoulders and upper back every night after taking a shower. In the shower I also use the Acne.org cleanser on my shoulders and back. I didn't experience any drying and within the first few days I saw results. It has been a month now and my back is 100% percent clear and feeling great. I use Acanya and Atralin gels for my face which have been working well too. I would say giving Epiduo a try on your back is well worth it!
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March 20, 2012

Pros:

couldn't tell any

Cons:

didn't really do anything for me

this product did neither good nor bad things for me
March 20, 2012

Pros:

Clears acne, reduces hyper pigmentation

Cons:

None

This stuff is wonderful. After struggling for a year trying to get my right cheek under control. I went to a dermatologist and he prescribed epiduo. I used it and saw a difference the next morning. My face was less swollen. I have tried everything under the sun to get my cheeks and chin under control and nothing worked until epiduo. The first week my skin was red and dry but nothing a little moisturizer didnt combat now I'm so happy my face looks better every day I've been using it a month and a half and I wish I would have gone to the doctor sooner. If you suffer from acne try epiduo it works!
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March 18, 2012

Pros:

Clears up acne
Doesn't smell like anything
easy to apply
Dries quickly

Cons:

Burns
Gives you dry skin
Makes your skin sensitive
Flaky skin

I used this at night, ONLY. I apply a pea sized amount to each section of my face. It burns a bit but it eventually goes away. At first, I started breaking out a little bit, but then it started getting clearer and clearer. Although it's making my skin dry and flaky, it's worth it cause it's clearing up my acne! I love it but hate how it dries out your skin :*( And I normally have really oily skin... I've been using this for like more than a week consistently. I got it free using medicaid.
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March 18, 2012

Pros:

Clears acne as well as spots

Cons:

severe dryness and redness

I started using Epiduo six days ago. I use a pea-sized drop all over my face once every night. My dermatologist told me to rub Cerave lotion into my skin to help dryness. The Epiduo leaves my skin extremely dry and Cerave, albeit a nice, high quality product, only works for a short time (a few hours). Aloe vera gel only makes my skin sting and redden more. After reading reviews, most people say the redness goes away in 7-10 days. Despite my having only used this product for six days so far, and the annoying redness, my skin is noticeably clearer. I've never had severe acne, it's mostly that my complexion gets spotted from past blemishes with a couple of pimples here and there. Epiduo seems to really be removing these spots, and so quickly too. The redness and dryness is uncomfortable and does appear to make your face look blotchy but I'd say, judging by my results so far, it's worth it. I recommend using this product with Cerave like I am, because it is a smooth cream for the skin and has SPF in it. Also, perhaps some home made masks of things like lavender oil, honey, oatmeal, green/chamomile tea, verbena, and other natural, soothing, nourishing things. I'm not sure how much it costs (I haven't filled my prescription yet, i've been using little bottles my doctor gave me in the mean time), but I think it's on the higher end of the line, between 20-30 dollars.
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March 15, 2012

Pros:

*Completely cleared up my acne
*Cheap
*A little goes a long way

Cons:

*Stains my pillows a little
*Takes a while to dry (before I can moisturise)

I suffered from moderate to severe acne for two years. I had a few cysts and a constant supply of big red painful spots and pustules around my mouth, chin and cheeks. I tried nearly everything. I went to my Derm and asked for Roaccutane. She insisted that I try Epiduo first. I reluctantly agreed. Initially I used this twice a day (against instruction!) and (not surprisingly!) suffered horrendous pain, redness cracking and peeling. I then started using Epiduo as described and saw my acne slowly disappear. It was amazing, I went from having a face dominated by acne to being 100% clear in about three months. I apply Epiduo to the affected areas every night then moisturise with Cetaphil. It's been 9 months since I started Epiduo and I probably won't ever stop using it. Just in case. I currently experience no side effects, I'd wholeheartedly recommend this product to anyone suffering with acne.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.