Topical Retinoid / Topical Antibacterial
Reviews
3.7
579 Reviews
Topical Retinoid / Topical Antibacterial
Efficacy
67%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid / Topical Antibacterial
Side Effects
Low-Medium
Topical Retinoid / Topical Antibacterial
Acne.org’s Real World Take
A way of using benzoyl peroxide in combination with the topical retinoid, adapalene, that studies show works a bit better than benzoyl peroxide alone. Comes with side effects for the first weeks and can bleach fabric. Note: When used correctly, benzoyl peroxide on its own can completely clear the skin.
Topical Retinoid / Topical Antibacterial
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Adapalene / Benzoyl Peroxide (Epiduo®)
Compare To Other Treatments
5
38.2%
4
27.3%
3
11.1%
2
8.6%
1
14.9%

Used Adapalene / Benzoyl Peroxide (Epiduo®)? Rate It:

Choose from 1 to 5 stars
July 10, 2014
Excellent!!!
This treatment is the one that provides best results for me. It is the only BP treatment which does not dry my skin severely or darken my complexion (I am an Asian Pakistani). You should apply it as directed for optimum results. I apply a pea-sized amount once every evening after using neutrogena pink grapefruit face wash. You may have initial breakouts but you need to give this treatment time to work. This has been the most effective product I have used in treating and preventing my acne, blackheads and reduced hyperpigmentation. If you have tried many products and they have not worked, please go to your doctor and ask for this product.
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July 7, 2014
NOpe Noope Nope
I really disliked epiduo. Had moderate facial acne and a good deal of cystic bacne in my first year of college, and when I finally went to the derm, she prescribed me this along with an oral antibiotic. Epiduo felt greasy and disgusting on my skin, and it absolutely did nothing. Actually made everything worse, since I stopped doing my proactive regimen when I started it. I was on it for five weeks with NO improvement. Finally now I'm on aczone and doing great. IF OTC BENZOYL PEROXIDE DOES NOTHING FOR YOU, PROBS IS A BAD IDEA. Benzoyl peroxide does nothing but dry me out in any form. hate hate hate. However, if otc benzoyl peroxide does SOMETHING for you, this may possibly help. Feels totally gross though.
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July 1, 2014
Love it!!!
I have suffered with mild acne since I was a young teen. I have tried all sorts of topical treatments and nothing seemed to work for me. Finally, I tried a sample of epidou and I really liked it! I have been using it for probably 3 years now and follow my schedule with it religiously. My skin has completely cleared up besides the pimple or two I get around my period. This was a drastic change to when I used to completely break out during that time. I will say it can be a little drying sometimes so I use a moisturizer as well. This is the only thing that has ever worked for me and I highly recommend giving it a try, and give it time. Your breakouts won't go away after a day! A few months my skin was clear and STAYED CLEAR!
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June 28, 2014
Absolutely recommend!
This worked wonders for me! I once had moderate acne, which was greatly helped by a 5% Benzoyl Peroxide cream and a change in my skincare. However, soon it didn't work so well anymore and I was left with mild yet persistent and extremely stubborn acne and red marks from old acne. I tried many home remedies, shop-bought creams, washes, masks, I tried changing my diet but that didn't work for me - and then my Doctor prescribed me Epiduo. The first time I used it, I made the huge mistake of treating it like my old BP cream which my skin could handle quite well. My skin burned so bad I nearly cried! I gave it a miss for a night and tried it again - this time I used literally a pea sized amount for my entire face. It still burned a lot but a little more bearable. I used it every other night whilst my skin built up a tolerance, and then used a moisturiser in the morning. I actually saw results pretty quick...within a couple of weeks I was getting compliments from friends and colleagues on how well I looked. Now I've been using it for 3 months and I only get the odd spot here and there (usually during that time of the month), which are quickly dealt with with Epiduo. It has helped fade red marks a little too which is a bonus. I do still have a few little bumps that it doesn't seem to be helping, but I'm the only person who can notice them. The only drawback I can think of is that after 3 months my skin seems to be getting oily, whilst I usually have normal/dry skin - the only change I can think of is the Epiduo. That said, I have changed my contraceptive pill, though haven't done any research into whether this can cause oily skin. Overall, I would recommend giving this a go. I was reluctant to at first, thinking - if BP didn't fix my skin why would this be any different? - but I'm so glad I tried it. I can now sit in board room meetings without feeling like the token acne-ridden teenager! It's important to understand that everyone's skin is different though, so what works for one person may not work for another.
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June 21, 2014
50%
I'm 17, female, have mild to cystic acne, depending on the season. My experience with Epiduo was good, I'd say. I began using it last summer. At first, I was horrified at my skin. I could not believe that a doctor would prescribe it to someone. What I was also doing was slathering it on, twice a day. More than usual. So of course, because I wasn't using it as prescribed, my skin was dry, irritated, itchy, and I was breaking out more. I kept at it for about two weeks and then put the product away in my medicine cabinet. A few months later, at the end of August, I was fed up with spending money on neutrogena and clearisil products that don't work. I decided to be patient, and give it a try again. I also read the package insert this time. It stated that acne may worsen during the first stages of treatment because it is treating all the acne you can't see. Which actually makes sense. A drug can't stop a blemish in the middle of it's cycle. The pimple has to become a pimple and get rid of the clogged pore, or it will just remain a bump under the skin, which makes the texture of the skin awful. So I stuck it out again for a few weeks. I would use it at night as directed, and not use too much. Using more product doesn't increase absorption. The only was to increase absorption is rubbing in, increasing the surface area that you apply the product, and applying to clean skin. I used it on my back and chest as well. I used a st. Ives lotion on my back and chest after I took a shower the next day to replenish the moisture I lost from using Epiduo. As far as face lotions go, I recommend clean and clear dual action. It has a very small amount of salicylic acid, not enough to overdry your skin. I also recommend yes to grapefruit moisturizer. It works great but it's a little expensive. My back cleared up with no scarring, the same for my chest. It was amazing. The texture of my skin improved immensely. My face cleared too, except I would occasionally get acne on my nose, which I attribute to my large pores in that area. What you have to realize is that acne is ongoing and you're always going to have acne prone skin. The best thing you can do is find a treatment that takes care of the main symptoms of acne: bacteria, oil, and clogged pores. If you don't treat the other symptoms your skin is experiencing, then the treatment won't work. Moisturize! It doesn't matter if your face feels greasy or gross. Do not skip a day of moisturizing or it will upset your skin's balance. Cleanse and exfoliate! Try using pink grapefruit daily scrub or a st. Ives scrub. Even use a gentle cleanser like cetaphil. Although you're not supposed to use salicyclic acid with Epiduo, my skin was clear using neutrogena's pink grapefruit scrub, clean and clear moisturizer, and Epiduo. The other thing that helped was patience. I wasn't looking in the mirror every day looking for results. I wasn't popping my acne, I was just letting it run its course and eventually it stopped showing up. Also, when using makeup, MAKE SURE IT IS NON COMEDOGENIC. I suggest physicians formula mineral wear, the most minimal coverage you're comfortable with, and apply it with a foam beauty round. They come in like 12 packs and are cheap to replace when the old one is nasty. Which is a good idea to minimize bacteria. Use your moisturizer 20 minutes before applying the powder. Use liquid foundation instead of concealer if you need more coverage. Also non comedogenic. Do all of what I just said, make it a routine, and don't watch for results. It will take a while but I promise this product works. The only reason I stopped using it was that my insurance changed and instead of 26$ a month, it was $240. No way I was paying that! Hope this helped.
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June 13, 2014
Great for Mild acne, but if you are a cystic sufferer than STAY AWAY
I started Epiduo + Doxycycline in October 17th 2012, nearly 8 months ago. The first three months were hell, red peeling skin and horrible initial breakout, I had to constantly moisturize and missed out of a couple of social functions because of it. After that my skin started to calm, and somewhat started clearing. This phase lasted about 2 and a half months, in which my acne was getting better but was leaving behind unsightly red marks. The red marks concerned me so I took a trip to the derm, who said they should fade in a matter of months. 2 weeks later I was back at the derms, because my face, chest, and back had EXPLODED in cystic acne and small red hard pimples, the Epiduo stopped working entirely and I am currently making the switch to accutane. If you suffer from cystic acne do not even bother with this, it does NOTHING to stop it. This is for people like young teens with mild acne or minor scarring they wish to heal.
January 20, 2014
Epideo GEL.

Pros:

clears up your acne
does wonders

Cons:

drys out face
causes redness

Well lets just say it has cleared up some of my acne, but not all. My face is SUPER dry and tight. I'm guessing it's a good thing and getting rid of the acne. You see a different in about 2-3 days. Then it gets dry. moisturize as much as you can, drink lots of water. Hoping it gets better!
January 19, 2014
Epiduo

Pros:

clears acne
less oily

Cons:

dry red itchy skin
painful to wash face

I have really oily skin and I'm prone to breakouts on my forehead so my dermatologist prescribed this for me. I have been using it for a month and my acne has cleared up somewhat. The product makes your face feel like its on fire when washing it or putting moisturizer and medication on. I would highly recommend not using soap but a gentle face cleanser while using epiduo. I have never had dry skin before ever and it is really quite flakey and red on my lower cheeks. Also the few breakouts that I have been getting aren't clearing up at quickly as normal. I wouldn't start using this during the winter and I advise being careful during the summer because I think I will be seeing a lot of painful sunburns in my future due to my now sensitive face. Epiduo served its purpose but not without consequences.
January 14, 2014
Brillant

Pros:

Clear skin
Heals acne scars

Cons:

Sunburn prone
Expensive
Rash

Suffered for severe back acne for years now, it wasn't only staying around, I was sick of it so I went to my local GP and was prescribed epiduo, I had no idea what to expect, 1 month later and I am COMPLETELY clear of my back acne. There was a hiccup as I did break out in a rash that lasted a few days. If I had known about what this medication when I first started breaking out and what it could do for me, without a doubt I would have got it. Try this out if you want results.
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January 8, 2014
Worst of the Worst

Cons:

very harsh
dry and flaky
inflamation

I tried this product when it was very new on the market and my doctor was hopeful it would work on cystic acne. ...she was wrong. My face was inflamed, itchy, rough and INCREDIBLY FLAKY. While new break outs sort of subsided, I wondered if the trade off was worth it? my skin looked all over worse with all the new side effects than it ever did with just pimples. I've been off it for a few months now but I think it might be the cause of my now SUPER sensitive skin. This product is very harsh and damaging.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.