Diane-35 : Oral Contraceptive

912 Reviews

Active Ingredients:
Cyproterone acetate 2 mg and Ethinyl estradiol 0.035 mg.

Inactive Ingredients:
Cornstarch, Lactose, Magnesium Stearate, Povidone, and Talc.

Tablet Coating:
Calcium Carbonate, Ferric Oxide Yellow, Glycerol, Polyethylene Glycol, Povidone, Sucrose, Talc, Titanium Dioxide, and Wax.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.


Used Diane-35 : Oral Contraceptive? Rate It:

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January 2, 2023
do it🫶🏼
lost weight, grew a cup size and haven’t had a pimple for like 2 months, absolute W
June 20, 2018
I think it is great! I originally got put on this with accutane (and my acne wasn't reaally that bad, but you need to take birth control with accutane and this is what my doctor put me on). I've been on it for 4 years now and had no regrets (yes the articles about people dying from blood clots freak me out every now and then). Not only has it completely cleared, and kept my acne at bay, but it reduced my facial hair (not that it was crazy). I think it is great. Made my gain weight a little bit (in places I'm okay with), and I don't think it has affected my mood. All in all, I am happy and recommend.
January 11, 2018
Give it time!!
I've had moderate acne all over my face ever since I hit puberty, and literally nothing I ever did or used made the slightest impact. On Jan 2017 I decided to switch from Levlen to Diane. For 6 months I saw little to no improvement, although I did notice that my skin would be clearer at the end of my cycle and that I was getting more cystic acne rather than lots of smaller pimples. On June 2017 my skin was at its worst- I had 4 giant cystic pimples on my birthday and I was so miserable. I was almost ready to quit but every cycle after that month my skin kept improving! Now I'm at the point where I can barely recognise my skin-its so smooth and soft, I don't have a single pimple on my face at the moment (something I haven't experienced since I was 12). I feel like a new person, and have finally ditched the heavy foundation and concealer I would always hide behind. So if anyone on this pill is frustrated or convinced it won't work for them, BE PATIENT!! I've honestly never felt better in my life and still can't believe I actually found something that works for me :)
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5 user(s) found this helpful

July 6, 2017
So many benefits, if you're patient!
Had my IUD removed after a year as I had nothing but bad experiences using it... acne, weight gain (8kg/ 17lbs) terrible mood swings and extremely low libido. I started Diane about a month after IUD removal. At first my acne got slightly worse and was quite moody and sad. I wanted to throw Diane out and stop taking it.. but I have heard to give it a few months to work and i'm so glad I did! About 2-3 months in my acne started disappearing, my periods are SO light and haven't had any cramps since taking Dianne. I have had no weight gain with Dianne and haven't had any trouble losing weight while on it. Not only that but my mood has changed dramatically. I feel happy and calm and so pleased I stuck it out and gave this pill a chance.
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5 user(s) found this helpful

June 1, 2017
Be Patient! It takes a while for it to start clearing you up.
Hi Ladies I have been using this pill for 5 months now. For the first month I did'nt see any changes to the acne until second and third month which were the worst. The acne worsened during those two months, cystic pimples which were red and puss filled were all over my chin and jawline. Not forgetting the scarring that came with those cysts. I was so tempted to ditch this treatment and look for an alternative therapy. But due to reading a lot of posts with similar stories, I was hopeful that maybe I needed to give the diane a little bit more time. Its not until I hit the end of month 4 mark did I start seeing some clearing on my skin. Its now end of month my and I am completely clear. So one needs to be very patient with diane, clearing of the acne takes a while. But its worth the wait.
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19 user(s) found this helpful

January 6, 2017
Seeing results takes time but it's worth it
It took 3 months for me to see an improvement but now my skin is the best it's been in years. I used to constantly get large, painful cysts around my mouth and chin but I haven't had one for about a month. This month I didn't even get a breakout on my period. This is the only medication that has worked for my hormonal acne. I did not have any side effects and I finally feel comfortable going out without makeup! I just hope that my skin doesn't get worse after I stop taking it.
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7 user(s) found this helpful

June 29, 2017
Hey did u get acne after u stopped taking this pill? Cos i am on this pill right now for more two months! Please help.
August 20, 2016
Before I start taking Diane 35, I was very skeptical about it, especially after reading all those negative side effects. To give you an idea of the severity of my acne problem, I had tried out a handful of different oral antibotics for almost a year, all the tropical treatments, and almost the OTC remedy/skincare/vitamin etc. You name it, I have tried it!!!!. My dermatologist was happy to prescribe me with Accutane, in fact, he even said that it would be a good option for me if I want my skin to clear up forever. I have consulted him about taking oral contraceptive, yet he said it wouldn't be too useful/permanently clear up my face. Above all, tho my period are not very regular, I dont have much cysts but mainly tons of small=medium pimples all over my face except my nose area. They do not really look like hormonal acne. I have struggled with acne for so long, it has ruined my social life and self-confidence, and almost turned me into a difference person. I can't stand it anymore, and before going into Accutane, I decided to give this a try. And GUYS THIS STUFF IS AMAZING!!!!! My face is cleared up within 3 months!!!!!! I felt like I have waited too long to try this out! I still have small pimples here and there, whiteheads, redness and all that. But at least my skin is smooth again! Regarding the side effects, yes, there are some side effects but it's not as scary as it may sound. For first month, I have experienced continuous spotting for like a good 10-15 days, sore (and bigger) breast, a bit migraine for a couple days and during the 7-day breaks (but nothing a painkiller couldn't deal with) , and just some pretty bad mood swing. However, there's no major discomfort of any sort. And my skin was better than ever. Plus most of the side effects got better once your body are well-adjusted to the drug. I didn't gain any weight at all, in fact, I started to work out more while I was on the drug. I lost some weight and now have slightly bigger boobs. For any girls who's suffering adult acne out there (ATTENTION: ADULT ACNE), give this drug a try before taking Accutane. Maybe it would take some time to work, maybe it's might not a permanent solution (touchwood), it did help regulate your hormone level and that really helps with your acne.
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34 user(s) found this helpful

July 20, 2018
Hi Nancy , your review as seem to be the best and most honest .Everyone as been saying that you will have hair loss , please tell me if this is true ? I currently going through the most with my skin and I've been advised to try out Diane, but I'm so so scared if the hair loss fact is true .
August 30, 2018
Hi Nancy, Thanks for your honest review. I need some help. It has been 15 days that I have been on Doxycycline and topical retinoid treatment. My dermatologist wants me to continue Doxycycline for another 15 days and then start Accutane. My gynecologist has prescribed me Diane35 for hormonal treatment. Can I intake Accutane and Diane35 at the same time? Thanks in advance.
June 19, 2016
Looking to forward to trying this out. Diane 35
OK so I haven't tried this yet, but I'm currently on 50 MG of spiro, depo provera and estrofem 1mg. OK here's the thing: Hormones circulate through our blood. So once you stop taking an synethic hormone your body is going to whack. I think if you just detox your body (blood) this would help you a lot in cleansing out the hormones. Even just in general. Also, Im assuming that this bc doesn't contain a progestin? I'm currently on depo provera so that I can take some form of estrogen. I live in the US so I'll have to get it some other way. I was going to get a packet of EE, stay on spiro and depo. But I think Ill switch Spiro for Diane 35 so I'll have the EE and a different form of anti androgen. f.y.I I've read that if you have too much estrogen it can turn to testosterone? This is from a forum: However, if you are not on androgen blockers and start to put oestrogen into your system your body may respond by producing more testosterone.   The higher the E possibly more response to produce T.   Some clinics and some professional are in a habit of reporting information in an inaccurate way to 'receive' your attention. I'll post an update once I start taking it. Wish me luck.
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1 user(s) found this helpful

April 16, 2016
Good for acne, possibly you will need to switch to other pills after one year
Where I live, this pill is known as "Diane Nova". I began to use it at the beginning of year 2015 (February), at the age of 22 and used them until the start of the year 2016 (also February). I've been suffering from acne since I was 12 years old, and when I was 22 my skin problems had been hurting my confidence for a good 10 years. I've even tried Accutane (at the age of 17-18, known in here as Roaccutan) but the results were not permanent, and my acne returned almost immediately after finishing the 1-year treatment. Because of the price and the unsatisfying results, I did not give it another go. During using these pills I had very little side effects that would be associated with the use of birth control. I experienced that my face and hair started to be less greasy than before. By 6 months of using, my face was pretty much completely clear - I'd no longer get the painful, big bumps that I used to have under my skin several at a time. Now I would only get possibly two tiny pimples at a time, during that time of the month. My mood and confidense improved after this. After almost 1 year of using, I started to experience pain during and after intercourse. I went to the doctor and she told me it was dryness caused by the hormones in Diane pills, and that it was not uncommon. She said that people usually switch to another birth control pill after their acne has cleared, commonly by about a year of using Diane, and prescribed me another pill. I switched to another pill known as "Femoden" and my skin has remained clear after after switching. I'm now 23. My chest and back are finally completely free of acne, too. On my face I only get tiny pimples occasionally. From my experience, I warmly recommend birth control pill as a treatment for acne. It cleared my skin and it takes care of contraception, I plan to use birth control pills until I wish to have children, so I can not speak from experience if the acne will stay gone after quitting birth control - only that I remained clear after switching to another pill. However, because of side effects the same pill/method may not work for everyone. I feared to get side effects, but experienced almost none. For me it did get worse before it got better, the doctor told me that clearing would take 6+ months. I hope you find the treatment that works for you! In my journey I have lost hope at many points. Hang in there!
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18 user(s) found this helpful

June 12, 2016
Helo I'm on dianne and I'm on month 2 and I feel like my acne is worse. How was yours at 2 months. How long did it take to clear
January 6, 2016
best skin in years, used to have severe acne
2015 was my worst skin year. I've battled acne since I was 12 and I turn 20 in 2016. In 2015 I had deep, painful, cystic breakouts all over my temples, cheeks, chin and jaw and whiteheads on my forehead. So I started taking zinc, vitamin d3, and Womensense Saw Palmetto Plus since my acne is hormonal. Saw Palmetto Plus contains vitex and saw palmetto. I also tried evening primrose oil but that didn't help so I stopped that after a month. So I took zinc, d3, and saw palmetto plus for almost two months and that cleared 80 percent of my cysts but I still had a lot of tiny pimples or closed comedones and maybe 5 cysts at once. Then Diane 35, which I started over two weeks ago. I've experienced no side effects so far. I was scared to take it because I didn't want to get an initial breakout. I'm an actor so it's imperative that I have smooth skin. I stopped the saw palmetto plus to take diane 35 which I worried about since the saw palmetto helped my skin so much. But I've had no initial breakout on diane 35! My skin improved further. Now, I only have 4 active spots and they're relatively small compared to what I suffered last year in 2015. I feel my skin with my hands and it's the smoothest it's been in 4 years. I still have a few closed comedones but not nearly as much as before. I have PIE (post inflammatory erythema red marks) and boxcar acne scars. I plan on going on isotretinoin since I know birth control is not a permanent cure. But I am so happy with the skin I have right now. PS I have Asian skin and I eat a pescetarian and often vegan diet. The only difference I've noticed from diane 35 is being even more prone to constipation but it could also be what I've been eating. Flax seeds usually do the trick if you have constipation. I'm still taking zinc and d3.
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7 user(s) found this helpful

January 8, 2016
I have now started isotretinoin/Accutane. Still on diane 35 as well.
June 18, 2016
Quit using that stuff. You are what you eat. I'm half asian. So I know what you're talking about. Eat more probotic foods, drink homemade fruit juice. Look up amla fruit. I use other fruits too and make my own drink. You need to detox your blood. Look up schishandra berries. Know in TCM to detoxify the body. Garden of like vitamins all made with veggies, no animal by products, all have probotics in them. If you can donate your blood so your body can create new blood. Good when you start changing your diet. Also onion and garlic. Water. Lemon water. I'm currently taking Spiro. I will try this diane 35 instead of spiro.