Ziana : Clindamycin (1.2%) and Tretinoin (.025%) Gel

Brand:
Reviews
3.5
397 Reviews

Active Ingredients:
Clindamycin Phosphate (1.2%) and Tretinoin (.025%).

Inactive Ingredients:
Purified water USP, glycerin USP, carbomer 981 NF, methylparaben NF, polysorbate 80 NF, edetate disodium USP, citric acid USP, propylparaben NF, butylated hydroxytoluene NF, and tromethamine USP.

The list of ingredients above is provided for informational purposes only. Always check the actual product label in your possession for the most accurate ingredient information due to product changes or upgrades that may not yet be reflected on our web site.

5
26.4%
4
33%
3
18.6%
2
12.1%
1
9.8%

Used Ziana : Clindamycin (1.2%) and Tretinoin (.025%) Gel? Rate It:

Choose from 1 to 5 stars
March 1, 2010

Pros:

Affordable, Easy Routine

Cons:

Does not clear Acne

Didn't work for me, I have used in small pea size amount and bigger size amount (noticed it worked somewhat better the less you use) I have been VERY patient as I have used this product for 2 1/2 months and It's basically an on and off thing with ziana. I get clear great looking skin for a week in exchange for 2 or 3 weeks of bad red pimples. Not worth it. I'm going back to the dermatologist in a week, hopefully I'll be put on accutane, this has been my 6th topical treatment and I've had enough!
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March 19, 2010

Pros:

Didn't make my skin any worst.

Cons:

GREASY GREASY SKIN.. Skin Wasn't ever consistently clear. Didn't help with hormonal acne.

it didnt work well enough for me to handle the oily skin. It was just as annoying as keeping up with acne itself
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June 18, 2011

Pros:

Bottle lasts for a long time.

Cons:

-Rather Expensive without rebate card
-Turned Acne breakouts slightly more severe.
_Didn't work as i had hoped/expected
-Doesn't sink in to skin well enough.

Every morning when I woke up and looked in the mirror, where i put the ziana gel i saw a glossy shine covering it, pretty much clogging pores. After 2 weeks, I actually noticed a pretty substantial improvement :) (this was also while taking Solodyn). However, about 5 weeks in, my skin plummeted to levels un-seen before. I had worse acne then I ever had. I got humongous white heads and even a few cystic like pimples. I immediately stopped using it and proceeded to use a very drying face soap (due to intensified levels of oil) and i used bactroban cream as a spot treatment. It luckily cleared ziana's mess. So I wouldn't really recommened this.
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January 7, 2011

Pros:

A little goes a long way.
1 step, once a day
Kinda expensive

Cons:

Didn't help much with acne
non-Stop purging
very drying

Here's my acne story. Around October, got a really bad break out while using Proactiv. Switched to Murad. Made everything worse. Went to dermatologist. Got Ziana. Cleared up the effect of Murad, but didn't help with any acne that i had before Murad, so now I'm back to square one. Ziana has something in it called retin-something lol that causes skin to purge. It is supposed to stop after a while, but my face never stopped purging. It also dried me out really bad, even though I used a heavy moisturizer twice a day too. This product didn't work for me, but it has been a miracle for one of my friends. Everyone is different. If your dermatologist prescribes this, try it. :) P.S.- I am a 14-year old girl. Thought that might help since adult and teen acne IS different.
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March 3, 2015
Not for me
My background: One to two zits in high school, nothing ever serious. Started college and I started getting this huge cysts around my chin and on my cheeks (definitely hormonal acne). Ziana showed really great results for me within the first two weeks and my skin was super soft! After that HUGE cysts came up everywhere. I've never be so self conscious in my entire life, I avoided contact and never went out on the weekend. As a college student, my skin should be the least of my worries, but it started to take over my life. My derm said that the cream would bring everything to the surface and I would see results around 3 months. Well, month 3 came around and my skin was the worst it's ever been. I stopped using Ziana and my skin looked better just after ONE day. (Not clear obviously, but the size in my zits went way down) I'm sure this is the miracle drug for some people, but it's just not for me.
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February 5, 2011

Pros:

It was free because my derm gave me a ton of samples.

None other for me.

Cons:

Provokes break outs, leaves big red blotches and open-sore-like spots, dries out skin completely.

I gave this product a rating of two instead of one because yes, it's true, after the hell of my ENTIRE FACE drying out completely, getting break outs in new places, and being red, itchy and burny for like a week, once the skin finally sheds away my "new skin" looked nice. For a few days. Then oil production started again. I don't really have oily skin but I still break out so my derm recommended it and after using it three times weekly for a month and just going through the same peeling cycle I gave up. This was not for me. I can only imagine this helping people with INSANELY oily skin...seriously, it's crazy how strong the stuff is.
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February 4, 2010

Pros:

Rebate card made it affordable.

Cons:

drying, made my face break out worse than before i even went to the dermatologist

Help! I starting taking Ziana about 4 weeks ago. At first, I didnt notice any change at all and now this week all of a sudden my face has been overrun by large cystic acne! Im so embarrassed and depressed and Im tempted to stop taking Ziana--Ill just live with what my skin looked like beforehand! How true is it that your skin gets worse before it gets better and how long is that supposed to last?? I havent even noticed this medication making a difference on blackheads. Will my skin get worse if I just stop cold turkey?!!
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January 28, 2011

Pros:

-might be good for someone with dry skin since it causes your skin to produce so much oil.

Cons:

-did not make skin any better! if anything it is worse!
-DRYNESS. in the winter i developed quarter-sized, itchy spots whenever i was out in the cold for more than 10 minutes!

first, i'm a 22 year old female. i went on accutane when i was 12, and that left me completely clear until about a year ago when my skin became covered with tiny whiteheads/clogged pores/comedones (still not really sure of the difference!). anyway, i had the kind of acne that doesn't look too bad from a distance because there isn't much redness, but makes the texture of your skin look very rough and unhealthy when viewed from close up. i am in college, so first i went to see my derm at home (the same one that prescribed me accutane when i was young) and he said my acne wasn't too severe but that he recommended i go back on accutane since i had a positive experience with it before. however, since i do not live at home, i was required to see a dermatologist near my college since on accutane you must be monitored. my doctor at college recommended i try ziana first before resorting to accutane (which i really respect, since i know all about accutane's side effects that you must deal with while being treated). basically, however, i am really sorry that i spent so much time hoping ziana would work. my doctor said it's great for comedonal acne (and that the retin-a brings your tiny zits to the surface so that they can finally disappear). i spent months believing that my skin was "purging" and that eventually my skin would get better, when in reality it just continued to become more and more covered with acne (both more small bumps and large zits). i'm sure ziana works for some people (and, as with all treatments, it is important to give medications enough time to work). however, i was really disappointed that there was no payoff to my "purging." i am now going on accutane which i hope will finally work.
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August 22, 2007

Pros:

Helps clear up large inflamed zits

Cons:

unbelievably drying and sooo harsh!

My skin is not usually sensitive at all and I have used other retinoids in the past such as tazorac. But this stuff tore apart my face. I followed the directions exactly but after a couple of days my face became so dry that it started to crack! I felt like I was wearing a facial mask for about a week and my skin was as red as a tomato! It hurt so much and I couldn't even go out of the house my skin looked and felt so terrible. I called the derm and he told me to switch to only using it every 3 days and slowly work up to using it every day. Although the irritation has subsided quite a bit it is still making a mess of my face even though it's been nearly a month!!! I only really have a couple of zits left but my skin still looks horrendous because this stuff has left marks that look and feel like burns!!! I'm so afraid they are going to scar! I was so much better off before this. I'd rather have some zits than what looks like chemical burns.....
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May 14, 2009

Pros:

Improves skin tone/texture. Helps with stubborn whitehead. Works relatively quick for a topical retinoid.

Cons:

Can cause a decent amount of irritation even after you've used it for a long time.

I used this for whiteheads that randomly started plaguing me when I turned 28. It honestly works. I've had my ups and downs with it, but the problem has pretty much cleared up after about a year of consistent use. In terms of agreeability, this stuff surprisingly caused virtually no irritation when I first started using it. After over a year, however, I've noticed it giving me a notable amount of redness and flaking on the corners of my forehead. Also, it never worked on my nose. On the contrary, it started giving me rosacea/seb derm-type symptoms (flushing, broken capillaries, severe flaking, red blotchy skin and small red bumps) after using it every night for about 7 months. My derm said this was impossible and prescribed some metrogel thinking I was showing early signs of rosacea. I'm Indian...so...yeah...not likely. Knowing the real problem, I stopped applying the Ziana to my nose and the symptoms are only now beginning to fade. Wasn't a pleasant situation.
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