Ziana : Clindamycin (1.2%) and Tretinoin (.025%) Gel

This product has not worked right away for me. I am breaking out wose than I was before, but I hope that is part of the process.

I am on week 3 of Ziana. I'm 25, female and just this past few months I've been getting crazy breakouts in areas I've never had before. I think it's stress related. Ziana has worked well so far. It cleared up areas where I had a lot of acne and the scars healed a lot quicker than they have before. I am also taking Doryx everyday (150mg) and washing my face twice a day with a glycolic wash and using Aczone as a daily spot treatment. I haven't seen a huge improvement, but I am seeing some improvement, which makes me want to stick with it. Everyone else on here says you have to be patient. I'm giving it another month. I have a few pimples now but no where near what it used to be so I am thankful for that. I also am getting monthly microdermabrasions from my dermatologist, which is really supposed to help. Have a dermatologist do your microderms, not an aesthetician. Dermatologists can go over your active pimples to suck everything out of them to bleed them out. Aestheticians cannot go over your active pimples. One word of advice to people: Your Acne is never as bad to others as it appears to you! Also, stress is VERY powerful. Your skin reacts to how you feel. Reducing stress should really help!

I mostly have blackheads, & small whiteheads every now & then. I have gone through stages of acne since I was in 4th grade to now (20yrs old) so I have moderate scaring. I have used everything from OTC washes&creams to prescribed pills, gels &washes. My doctor gave me Ziana &said it could take 3 months for it to start working. The good thing was it didn't break me out worse when i started using it. The bad thing was it didn't help me either. After exactly 3 months of use I went back to the dermo, it didn't make a difference at all except make my skin VERY oily. Another thing is if my doctor didn't give me a card to pay $30 for a tube it would have cost around $350! One 60g tube probably lasts 6 months or more though. Even though this didn't work for me doesn't mean it isn't going to work for you. I learned over the years the most important thing is to keep using your meds for as long as prescribed, 2 weeks of dry skin red skin is better then being broken. suck it up and stick with it.

First, I want to share my background. I have never had a problem with acne. I have always had very smooth clear skin, with an occasional outbreak. I started washing with proactive in 2006 when I was 18 for prevention of those minor outbreaks (I don't recommend this because it destroys your skins natural barrier). Two years ago, in 2011, I started getting a cystic pimple every couple months, that I would handle by getting a cortisone injection. Not a big problem. Then Last year, in May 2012, I got my mirena birth control removed. I had an AWFUL outbreak. Huge pimples that wouldn't go away. One swelled up after it popped when I washed my face.. it was half the size of my forhead. I had cystic pimples, surface pimples, and clogged pores. My dermatologist put me on Doxy, spirolactone, and retin-A. After a few months, and a couple deep cleansing facials, my skin was clear... but I still had scars. In August, I decided to stop using Retin-A because my skin was still red. I started using Pro-Active again, and continued taking Doxy and Spiro. My scars went away in less then a month, and I had completely clear beautiful skin for about 6 months. In February, 2013, my skin started looking red and a little oily. By April, I started getting minor clogged pores that would go away fairly quickly, and I started getting cystic pimples every once in a while. I decided to stop washing with Pro-Active In june because I found out that it can cause oily skin. I also stopped taking doxy because it wasn't preventing acne anymore. I started using Jojoba oil to cleanse, but this only lasted a month because it was cause tiny little white heads to surface all over my face. I started using Cerave to cleanse. It doesn't create acne on my face. I did have clogged pores on my chin and forehead from the Jojoba oil. They are skin colored tiny bumps. I had a similar reaction years ago. I've now learned that it just doesn't agree with me. By August, I was getting more and more cystic pimples. Usually only one at a time, but when one would go away, another would appear. My dermatologist prescribed me Klarons. This did nothing for my skin. The cystic pimples kept coming and the clogged pores stayed where they were. I used it for over a month before I stopped. In September I decided to risk using Proactive again. It did nothing. It didn't make it worse or better. My skin was still pink, still a little oily, still had the clogged pores, and I was still getting those dang cystic pimples. This is when the Dermatologist prescribed me Ziana........ On September 25, 2013 I started using Ziana, and also had a bad cystic pimple injected. First week: (9/25) peeling. Red face. surface acne and scars start to go away. No change to clogged pores. Cystic on on left side of nose goes down but still under the surface. Second week: (10/2) less peeling. Red face. Scars fading very quickly. No change to clogged pores. Cystic on on left side of nose starts coming back... Two heads. Cystic appears on right side of nose. Third week: (10/9) (Stopped spirolacton on 10/11) New Small pimples show up but come to a head and go away quickly with in a couple days. Oily skin. Less peeling. Red face. Old scars almost gone. New scars fade quick. Both cystic pimples still present but no pain. One deep clogged pore is gone after popping it, but 8 remain. Forth week: (10/16) Tiny amount of peeling. Red face. Oily skin. Old scars almost gone. New scars still fade quick. Both cystic pimples still present, the one on right is forming a white head. Deep clogged pores still there. I'm getting the two cystics injected tomorrow and I will be back to update how this week goes. I have my fingers crossed...

Within 3 days my face felt as smooth as a babies behind. Texture was consistent and glowing. However the diarrhea is a bit concerning- I will probably have to stop. The warnings speak about colitis- something I dont want to risk. I might have to try something else. But my face feels incredible. I'm 28 and it has not felt like this since I was like 7.

I've been using Ziana for 4 weeks now. I'm really glad I came to acne.org to check the reviews -- I was worried that it wasn't working, but most people below are saying that it takes about 6 weeks to see results. At first, my acne got a tad better...and now, at week 4, it's worse. I'm looking forward to an upswing soon, if everyone else is right! They say to use a pea-sized drop of the stuff, but I find that it's not nearly enough to cover my entire face. I end up using about two peasworth -- one for each half of my face. Everyone else reports excessive drying, but I'm not seeing that. In fact, my derm-o told me to STOP using moisturizer while using Ziana. If my face gets dry, she said, use less Ziana -- don't introduce or increase moisturizer in an attempt to compensate. I only had one of two dry patches near the corners of my mouth, but they went away with a single drop of CeraVe on each patch. I'll report back after 6 weeks!

There are better products on the market but it might be worth a try for light to moderate acne sufferers.

Try it! It works

I have been on this product for a month and a half and I saw improvement. But then I got a sunburn, and my face is peeling, and it is not working as well. I would recommend this but, you have to be patient. I'm a 15 year old female, who has been sruggling with acne for 3 years, and I've learned you just have to be patient. As difficult as it is, just wait it out, and wear LOTS OF SUNSCREEN!

I'm 19 years old and I have delt with acne for 8 years. It has been a battle to keep my skin clear. I have awful cystic acne. It takes about three to four weeks for one of my pimples to go down. I have really sensitive skin so they look blue like bruises. It is very hard to cover these spots and it gets harder when they are really dry all around the cyst. My acne makes me really depressed and keeps me locked up in my dorm room. I have been on Ziana gel for about a month and I have not seen any improvement in my cystic acne and the acne around my mouth has gotten so much worse because of how dry the Ziana makes my skin. It hurts to open my mouth and make expressions. If you don't have severe cystic acne, I would give this gel a try. But if you do, I wouldn't waste your time or money on it. I am going back to the drem to try something new this week. Best of luck to all of you that try this product.