Ziana : Clindamycin (1.2%) and Tretinoin (.025%) Gel

Ziana definitely attacks acne, but there is a huge catch. I was initially prescribed Ziana to cure the whiteheads and blackheads that were stubbornly appearing on my forehead. For that, it worked great. In fact, I should have used it for solely that purpose. In a follow up appointment, my dermatologist recommended it for my whole face. Bad idea. I had pretty mild acne on my cheeks and chin, but this stuff made it a whole new ballgame. I am just weening myself off this stuff and realizing that it made my acne worse in these areas. Might as well have not used anything. Good drug for what I said it cured, but otherwise, forget it. On paper a combination of retinoid + antibiotic should work well, but for whatever reason the results for this medication are mediocre. That's pretty much the gist of it.

I didn't get the dry, red, flaky skin that others have been talking about when using this product. I didn't get that at all actually. What Ziana did was greatly increase the oiliness of my skin overall - yuck! I had oily skin to begin with and now when I wear make-up I have to blot every hour. I have been using Ziana for about 12 weeks and haven't had any large cysts during that time, but still get random pimples that don't come to a head. They annoy me. Oh well.

Great product if you have no side effects. My girlfriend used this once for her acne as well and had horrible diarrhea. I used this with minocycline. It may make your acne much worse if you use it alone. Even with the combination, I started getting minor bumps in places I have never had acne. After about a week or two those went away and my skin is better than it has ever been after 9+ years of acne. If you need more than one big tube it will cost something like 500 dollars. Even if you have decent insurance, why do you think premiums are skyrocketing? People buying things like this with their insurance without considering the cost.

My acne was bad and got progressively worse after I started this medication. I have HUGE bumps on my cheeks and jawline that make up draws more attention to. It's only been a few weeks but I don't see any improvements. My doctor said the cocktail I'm on (Doxycycline, Clenia and Ziana) will get worse because its "flushing the impurities to the surface". This is my 3rd time on this medication, all my doctors insist on giving it to me, after I've said time and time again that it didn't work.

Used this some years ago when I was living down south - it was prescribed by my GP who had no idea about skin but said lots of his patients liked it. It did nothing for me and was expensive, so I stopped after a few months.

ive been using this for almost 3 months now. i was surprised that i didnt break out as bad as i read others did (purging) but it was just normal acne for me. it actually started clearing up in like 1.5 - 2 weeks. my skin looked and felt smoother. i just wash my face with olay face wash and then apply 15-20 min later only a pea-size amount like it says. i read somewhere to apply it like 20 min after u get out of the shower/wash ur face or it causes more drying of the skin. i also put on neutragena moisturizer in the morning. definitely such an improvement. not perfect but pretty darn close. def happy with the results. no more worrying and stressing about pimples and how to cover them! :) its also really cheap with my insurance and the card they give u. and the tube seriously lasts forever. annnnd its clear gel unlike some of the other products i use where they r white and i walk around at nite with white stuff all over my face. anyways, i love it :) and def am so glad i got on it!

I've been using this for about 12 weeks and although it's definitely improved the appearance of my skin in general, I can't say it's improved my acne (which is mostly small, deep zits without a head that I've had for YEARS.) It's definitely worth it if you're prone to painful, cyst-like pimples. I haven't had one since I started using.

I used ziana gel for almost a year and a half an I still use it. My skin has really improved even though I still have acne. The main reason I started to use ziana gel was because I had so much acne on my forehead an now I have nothing there. I suggest not putting it on not affected areas. If you put it on your cheeks and nose, it will bring up new acne. My nose is now the most affected area and then there is just one cheek which is affected. I also suggest using a cleanser such as neutrogena oil free acne was, the cream one.

I extremely recommend this product because it is absolutely an agent that help me have no acne of my face.

I have suffered with large, deep acne cysts for many, many years. The last tretinoin I was prescribed left horrible bulging cysts the size of a quarter and terrible scars. Some surgical removal was required. When my dermi prescribed this, I thought I was in for more of the same. Instead, the cysting stayed minimal and my face has really cleared up overall. I still get large deep cysts from time to time, but this is really the first topical that has kept things from really spinning out of control. My biggest problem is the price. My insurance won't cover it because I'm over 35, and that's just wrong. After all these years of suffering I've finally found something that helps and they won't cover it. It costs $410 a tube here. My dermi is giving me samples, which I greatly appreciate, but I still have to buy a tube every so often.