11 minutes ago, cnb30 said:

Except no doctor I talk to will report such things. And also wouldn't mass hysteria atleast bring such issues more towards attention

Believe me, i feel as you do.

Make your doctors report it. Make your parents report it.

Are you not also angry at all the guys who might have stopped you taking accutane but were unable to because they kept quiet!!!

5 minutes ago, cnb30 said:

11 minutes ago, hatetane said:

Just out of interest - would you speak out in the media about this?
Men are silent. We are all supporting merck with this silence.

Kudos Accuity and Indigo who have spoken out but unfortunately the message is not strong enough.

Am I on my own with this way of thinking or does anyone else agree?

I'd be down to speak about this though my psychologist and psychiatrist would probably try to discredit me and make me shut up

You have a voice, use it. If you are strong others will follow you and speak out too.
You must have local member of government - department of health you could talk to.
Go to the papers - they are always looking for a story.
How do you feel about young innocent teenagers being giving this drug everyday while all we do is visit this forum.

Shame on all of us for not doing everything we can to stop others taking accutane!

19 minutes ago, cnb30 said:

24 minutes ago, hatetane said:

Just out of interest - would you speak out in the media about this?
Men are silent. We are all supporting merck with this silence.

Kudos Accuity and Indigo who have spoken out but unfortunately the message is not strong enough.

Am I on my own with this way of thinking or does anyone else agree?

I'd be down to speak about this though my psychologist and psychiatrist would probably try to discredit me and make me shut up

You have a voice, use it. If you are strong others will follow you and speak out too.
You must have local member of government - department of health you could talk to.
Go to the papers - they are always looking for a story.
How do you feel about young innocent teenagers being giving this drug everyday while all we do is visit this forum.

Shame on all of us for not doing everything we can to stop others taking accutane!

Look Fchawk, you are not the only one who suspects TBI. PFS guys considering it too.
https://www.facebook.com/PFSFoundation/

If you guys haven't yet, it be a good idea to get a copy of your medical records from your dermatologist. Showing the dosage, duration and age when you took accutane.

Speaking of hyperbaric oxygen chamber.

14 minutes ago, guitarman01 said:

If you guys haven't yet, it be a good idea to get a copy of your medical records from your dermatologist. Showing the dosage, duration and age when you took accutane.

Just got those.
Same with all blood tests etc - keep your own records.

I have said before - doctors overlook high/low within range and even results that are slightly out of range - you can't trust them!
Got to take charge of your own health - we have all learnt that.

1 hour ago, TrueJustice said:

As far as I'm concerned me going in to see multiple doctors and specialists over the years - I've lost count how many and briefing them on my tane experience is my reporting. As to what they all do with the info provided is anyone's guess.

I only recently debated the madness of this drug with my doctor, she said unfortunately most patientswho come to see a doctor retain about 10% of info provided to them, her point being she could warn of the dangers of Accutane till she's blue in the face - many ( not all ) will still decide they want to go on tane it to fix up their acne. This ex applies not just to Roaccutane.

For me back in 1998, if you were to give me a comprehensive list of side effects I'd of looked at other options to fix persistent acne that was only on my back....absolutely no doubt about it!!

Well you got to remember that most doctors are supporting accutane and still calling a miracle drug.
I saw 3 doctors on route to accuatne, knew about associated suicide but all three doctors dismissed this and said nothing had been proven.
Even now, so many years later, I just can't accept their ignorance.

I personally think that if the extreme sexual sides were cautioned in the packet and also stated that could be permanent - that would be a deal breaker.
Do you all know that propecia/fin sexual sides are now listed as a side effects but only as a temporary side effect.

I spoke to a pharmacist the other day who was telling me that liriam is safe to take.
Not only that but she said every side effect of medication will cease upon stopping medication.
A different pharmacist said the same thing to me many years ago.

ignorance at it's finest
loving pharmacist Ben Fuchs who says 'No' to medication!

This guy went on TV, did a hunger strike outside merck and is taking legal action - why are accutane guys not doing this?

Demyelination seems like a real probability that could effect everything from muscle weakness, nerve sensitivity, digestive tract, brain fog.,depression . Even if this didn't show up on a mri as multiple sclerosis like, there could still be slowed nerve impulses.

I would encourage everyone to keep the talk constructive. Saying we should commit suicide to get attention is simply crazy, and this forum loses volumes of credibility with such talk. I advise those individuals suggesting such things to see a psychiatrist.

As for the TBI theory, are you guys saying that our symptoms aresimilarto the long-term effects of TBI, or what? If so, how could we learn from this theory to help us in a proactive way

On 2/27/2017 at 5:31 PM, Justdry said:

You know how you say our immune systems are damaged - Do you get sick more often from minor things such as colds, flu etc... ?

The reason I ask is that i very rarely catch any bugs or anything, even when everyone in my office and household have them, i still don't.

This being the case would LDN still be worth trying ?

On 2/27/2017 at 3:03 AM, asdfghjkl123456789 said:

I'd be down to try naltrexone. Gotta become an alcoholic/heroine addict first though.

On 2/26/2017 at 5:01 PM, TrueJustice said:

Yep so true and why I've been banging on about gut health for ages. Prob is not even a gastroenterologist can do anything for you, sure I had my reflux prob fixed but I'll bet my bottom dollar the "ulcerated esophagus" discovered is not something I was just born with, I'll bet it was started by tane as mentioned on previous page!

I can't be bothered going back to fight it though, you're wasting your time debating anything with doctors or specialists, even if you do have one on your side there's nothing they can do for you.

Thx so much for sharing your LDN success. Just a question, can you get it online or do you have to go through the nauseating process of seeing a doctor to get it??

On 2/26/2017 at 5:06 PM, tanedout said:

This sounds quite promising, and if it's helping with digestive issues I'm wondering if it would help normalise gut flora, and I'm assuming the absorption of nutrients would be improved.

Anyone with sexual sides tried LDN? According to some studies it can be beneficial;

http://www.peaktestosterone.com/Testosterone_Naltrexone_Erectile_Dysfunction.aspx

On 2/28/2017 at 9:00 AM, cnb30 said:

 

I stopped getting sick with flu often once I quit eating gluten. However, the low-dose Naltrexone therapy has almost completely resolved the following issues for me, which have plagued me for many years: Waking up with a sore throat daily (from GERD which may be resolving), waking up stiff and sore muscles every morning, loose stools and irregular bowel movements, low energy, brain fog, generalized anxiety and depression. Oh, and and erections are rock hard for the first time in years (sorry for the graphic information). It's not necessarily a cure-all, but I think it helps normalize immune function, and to boost the body's functioning and overall health. You can obtain it online, through various international pharmacies, however the advantage of having a doctor prescribe for me was so he could monitor my success. Also it is free with my insurance. As I said before, I think getting the 50 mg pills of naltrexone, and then making your own LDN by dissolving them is the way to go...no fillers, no going back to the pharmacy every month, and you can adjust the doseage as you need. My doctor was not going to prescribe it, except that I joked that I would start shooting heroin and drinking alchohol like a fish and then come back to him for Naltrexone. I guess he realized that it was easy enough for him to prescribe Naltrexone for "alcohol use" (not abuse, because that can effect your life insurance down the line, etc.) and if I use it off label then he is absolved from responsibility. Here is how to make your own LDN: [removed] If you must obtain it online because your doctor won't prescribe, etc. here you go: [removed] I should mention that I have been getting these great benefits by taking the lowest of the low dose recommendation (1.5 mg). At that rate, a 30 day supply of Naltrexone will last me almost 3 years (or 1000 days) of low-dose Naltrexone. The immune system seems to be implicated in the overall dynamic of post-Accutane damage. Other glandular cells beyond sebaceous may also be vulnerable to "shrinkage" from Accutane. Just a thought.

On 3/15/2017 at 11:03 AM, CHIRON said:

 

 

I stopped getting sick with flu often once I quit eating gluten. However, the low-dose Naltrexone therapy has almost completely resolved the following issues for me, which have plagued me for many years: Waking up with a sore throat daily (from GERD which may be resolving), waking up stiff and sore muscles every morning, loose stools and irregular bowel movements, low energy, brain fog, generalized anxiety and depression. Oh, and and erections are rock hard for the first time in years (sorry for the graphic information). It's not necessarily a cure-all, but I think it helps normalize immune function, and to boost the body's functioning and overall health. You can obtain it online, through various international pharmacies, however the advantage of having a doctor prescribe for me was so he could monitor my success. Also it is free with my insurance. As I said before, I think getting the 50 mg pills of naltrexone, and then making your own LDN by dissolving them is the way to go...no fillers, no going back to the pharmacy every month, and you can adjust the doseage as you need. My doctor was not going to prescribe it, except that I joked that I would start shooting heroin and drinking alchohol like a fish and then come back to him for Naltrexone. I guess he realized that it was easy enough for him to prescribe Naltrexone for "alcohol use" (not abuse, because that can effect your life insurance down the line, etc.) and if I use it off label then he is absolved from responsibility. Here is how to make your own LDN: [removed] If you must obtain it online because your doctor won't prescribe, etc. here you go:[removed] I should mention that I have been getting these great benefits by taking the lowest of the low dose recommendation (1.5 mg). At that rate, a 30 day supply of Naltrexone will last me almost 3 years (or 1000 days) of low-dose Naltrexone. The immune system seems to be implicated in the overall dynamic of post-Accutane damage. Other glandular cells beyond sebaceous may also be vulnerable to "shrinkage" from Accutane. Just a thought.

So basically when you talk to your doctor you just ask for Naltrexone?

The low dose is just that - you take a low dose of it?

Any side effects? I'm sure there must be some from long term use?

I know we should stay on track and investigate TBI but I'm also of the belief tane before it caused any brain damage absolutely wreaked havoc on our gut which as we all know is where our immune system starts.

After grinding my teeth for half the night, the first thing I notice in morning is this hunger pain feeling in my gut, this happens every day. It's only made slightly better if I take a probiotic before going to bed.

Just can't heal my gut.....yet.

The studies are there, was just reading keeping vitamin D levels between 50 and 80 decrease the risk of developing multiple sclerosis (a demyelination disease) by 50 percent.

8 hours ago, TrueJustice said:

After grinding my teeth for half the night,

I'd maybe look into getting a mouth guard if you don't have one . Constant teeth grinding can effect your sleep and breathing, chip your teeth, damage your enamel, maybe contribute to gum recession, and cause stress on your jaw which can lead to jaw pain and headaches. Not all of these might happen, but it's a possibility.

17 hours ago, guitarman01 said:

Demyelination seems like a real probability that could effect everything from muscle weakness, nerve sensitivity, digestive tract,  brain fog.,depression . Even if this didn't show up on a mri as multiple sclerosis like, there could still be slowed nerve impulses.

Absolutely. You know what a nightmare it is getting a diagnosis of M.S.? People get test after test, second and third opinions. It's absurd. And people with M.S. speak of experiencing odd symptoms years before the worst took hold. Identifying demyelination from Accutane or Finasteride would be even more difficult because the demyelination would be limited to the scope of what 5-alpha reductase affects. It wouldn't be body-wide like it is for M.S. Nonetheless, this explanation makes perfect sense to me. It may explain why symptoms  can take a long time to show up. (Although neurosteroids have other neuroprotective effects that may have consequences if we lack adequate amounts for months.) Accutane VERY likely depletes neurosteroids like we KNOW Finasteride does. But of course not everyone would manifest symptoms right away, as neurosteroids like allopgregnanolone have long-term duties. There's a reason our bodies regularly produce these neurosteroids. For example, they regulate neurogenesis as well.

Demyelination is a gradual, ongoing process. So is neurogenesis. So this also means that even if we restore 5AR function and neurosteroid levels to EXACTLY as it was before Accutane, we still have to deal with the potential consequences of prolonged neurosteroid depletion. That's why experimentation will never tell us what is definitively wrong, only research will. Lastly, let's remember a PFS doctor (Dr. Crisler) is on record suggesting  demyelination is, in fact, a component of PFS. I have no shame making appeals to authority.
 

21 hours ago, hatetane said:

Kudos Accuity and Indigo who have spoken out but unfortunately the message is not strong enough.

Thank you. I'm in this for a long haul. I am still waiting on word for the documentary pitch I made regarding Accutane. The man who approached me to make it appears to be affiliated with someone who was involved in a high-profile case against Accutane. A cynical part of me thinks I was just being used to make an informational video that would assist someone in pushing a legal case against Roche, but hey, that's life. I was told the final documentary could potentially appear on VIce and Netflix. I am still holding my breath, but I have to acknowledge it may not go anywhere (for either logistical or sinister reasons; sinister being there was no opportunity in the first place). No hard feeling either way, though. You have to do what you can to get what you want, I suppose.
 

On 3/13/2017 at 10:26 PM, TrueJustice said:

For too long now I've been grinding my teeth when I sleep ( wonder why ) so I've decided I'm going to try "Tianeptine" I believe it's good for combating this as well as lifting mood, please share if you've had good results from this product?

Tianeptine is excellent. I was able to use it for a year with no withdrawal symptoms, compared to the time I used Zoloft for a month and had brain zaps for three months and sexual dysfunction for nine months. I can use 25 mg per day and experience effects that last most of the day, including afterglow effects. Although it doesn't necessarily directly influence my brain fog, it addresses the secondary symptoms such as irritability and social withdrawal.This medicine doesn't even give me headaches. I have no idea why it isn't used more often for depression. Oh yeah, because it is off-patent and no one can profit from it. Watch it become a scheduled drug soon, lol. Just never use more than 50 mg in a given day, and stick to the Sulfate version. It has rare addiction potential I guess (but this is likely mitigated by using a slower release version like Sulfate), but I was able to quit cold turkey no problem. I just missed the mood boost, as it IS an antidepressant. Caffeine is way more addicting. Note: LDN and Tianeptine cannot be used together.

On 3/15/2017 at 12:35 PM, TrueJustice said:

So basically when you talk to your doctor you just ask for Naltrexone?

The low dose is just that - you take a low dose of it?

Any side effects? I'm sure there must be some from long term use?

I know we should stay on track and investigate TBI but I'm also of the belief tane before it caused any brain damage absolutely wreaked havoc on our gut which as we all know is where our immune system starts.

After grinding my teeth for half the night, the first thing I notice in morning is this hunger pain feeling in my gut, this happens every day. It's only made slightly better if I take a probiotic before going to bed.

Just can't heal my gut.....yet.

Not really any side effects to speak of, except for vivid dreams for the first week or two...not a bother because the dreams are pleasant or neutral for me, considering that I have had nightmares and unpleasant dreams for years before (if I could remember them at all) with an occasional pleasant dream. I think this may be due to general anxiety reduction with LDN use. Here is some information on LDN. [removed]

It be more extreme, but I wonder if a lumbar puncture would reveal something that isn't showing up on blood test for people showing possible signs of neurological symptoms, or even a mri of the spine. Actually I take that back, it wouldn't be extreme at all if it revealed something, especially if it was something we ended up having in common.

On 3/14/2017 at 9:37 AM, Kynarr said:

Hey guys,

I'll take some time to report back on TRT this week. So far so good. I'm not sure it's the cure I was looking for, but mood wise, I feel like there are improvements. I'm probably getting my hormone levels checked this week, so within a couple days I'll know how its changed since.

Quick question regarding Zinc, as it's always been confusing to me that we'd supplement it when it's a 5-ARI. I finally bought some yesterday, and took 50mg zinc citrate before bed. I feel very odd mentally. Extremely thirsty. Face skin is burning with how dry it is. No libido, at all. Is this common for you guys when taking Zinc? It feels horrible. I'm used to drinking like 20 glasses of water a day... but I'm just.. so thirsty right now...

I am blossoming like a beautiful acne flower.

3 minutes ago, guitarman01 said:

It be more extreme, but I wonder if a lumbar puncture would reveal something that isn't showing up on blood test for people showing possible signs of neurological symptoms, or even a mri of the spine

http://www.curezone.org/forums/am.asp?i=423167
spine degeneration

Support for Iodine protocol restart after accutane.

https://forums.t-nation.com/t/about-the-t-replacement-category/38/2?u=ksman

According to the Textbook of Medical Physiology, essentially all hormone receptors are dependent on iodine to some extent, which increases the sensitivity of the receptor to the hormone it is related to. For example, iodine can increase the sensitivity of insulin receptors, which is of importance for diabetes, and it can increase the sensitivity of the receptors for neurotransmitters in the brain, such as serotonin and dopamine, which affect mood and cognition. Other hormones affected by iodine concentrations include testosterone, FSH, LH and cortisol.

anecdote:

KSman wrote:

But why do we worry about these things in a TRT context? Both hypothyroidism and adrenal fatigue undermine your metabolic capacity. TRT often restores one's metabolism to a youthful state. However, if your adrenals and thyroid levels cannot support that restored metabolic state, you hit the wall, crash or whatever you want to call it. In these cases, guys go on TRT and do not do as well as they should, or simply feel unwell or worse than before they started TRT. So TRT finds these weak links, and surprise! Doctors do not get understand this. So again, you need to be the expert and find a doctor who is not an idiot.

http://www.ijdvl.com/article.asp?issn=0378-6323;year=2016;volume=82;issue=5;spage=587;epage=588;aulast=Uyar

Karadaget al. initiated isotretinoin 0.50.75 mg/kg in 47 acne patients. They found that levels of free triiodothyronine, thyroid stimulating hormone and thyroid stimulating hormone receptor antibody decreased significantly at 3 months of isotretinoin therapy. Karadaget al. stated that there were no significant changes in the levels of thyroglobulin, antithyroglobulin or anti-thyroid peroxidase after commencing isotretinoin treatment.^[7]In contrast to the above studies, our study revealed a statistically significant increase in thyroid-stimulating hormone (P= 0.018).

Several studies have indicated that isotretinoin and other retinoids affect cell cycle progression, differentiation, apoptosis and cell survival in a variety of cell types.^{[19],[20],[21],[22],[23],[24],[25]}Interestingly, isotretinoin treatment of mice results in both decreased hippocampal neurogenesis and a reduction in the hippocampal volume.^[23],[24]The reason for the increase in thyroid stimulating hormone observed in our study may be a reduction in thyroid volume as a result of the direct apoptotic effect of isotretinoin on the thyroid cells. Isotretinoin is known to increase iodine uptake in thyroid cancers, facilitating therapy.^{[26],[27],[28]}This effect may also have induced volume reduction in the thyroid gland. As a result of the reduction in thyroid volume, free triiodothyronine and free thyroxine levels may have decreased and thyroid stimulating hormone level may have increased.

We enrolled patients with normal thyroid function. None of the patients experienced clinical symptoms of hypothyroidism such as increased sensitivity to cold, unexplained weight gain, puffy face, hoarseness, thinning hair, slowed heart rate or impaired memory after isotretinoin therapy for 4 months. Some of the symptoms were ignored because they might also occur as a result of isotretinoin treatment such as fatigue, dry skin, depression, muscle weakness, elevated blood cholesterol level, muscle aches, tenderness and stiffness and constipation. However, drug usage in patients who have thyroid dysfunction or are clinically hypothyroid may worsen metabolic pathology and induce irreversible hypothyroidism.

The major limitation of this study is the lack of follow-up data after the cessation of isotretinoin therapy. Another limitation is that we could not analyze men and women separately.

In conclusion, the increasing number of studies assessing the effects of isotretinoin on the thyroid gland will help clinicians to predict its side effects and to plan treatment accordingly. The next step in generating such data could possibly be expanding our study to include more patients and a longer follow-up.

Good post on Iodine/receptor relationship!

So has anyone been on Iodine long enough to see noticeable results? Anyone been on Iodine alone so they can say for sure that It was Iodine that gave great results and not something else they might of been taking at the same time!!??

Id like to hear that Iodine by itself is enough, not that we have to have it with LDN or Testosterone boosting drugs or something yeah to get results!?

https://forums.t-nation.com/t/about-the-t-replacement-category/38/2

KS man - thyroid basics explained is worth a read. Don't forget to expand the full message. (Iodine)

1 hour ago, TrueJustice said:

Good post on Iodine/receptor relationship!

So has anyone been on Iodine long enough to see noticeable results? Anyone been on Iodine alone so they can say for sure that It was Iodine that gave great results and not something else they might of been taking at the same time!!??

Id like to hear that Iodine by itself is enough, not that we have to have it with LDN or Testosterone boosting drugs or something yeah to get results!?

I don't think anyone will say iodine is going to solve all you problems.
There is an iodine patch test you can do at home if you want to try that.
You can test you temperature - I just posted, KSman explains what temperature to work with.
and the iodine protocol looks so good because many of the supplements have been tried and have helped individuals along the way.
It is a straightforward easy to implement protocol and not harmful so why not give it a go.
Also we don't want quick recovery which is a temporary fix.
I suggest at least 3 months - slowly helping your body to get back to where it should be.

The protocol was originally posted by a recovered PFS guy.
Remember selenium is important if you are supplementing with Iodine.

https://www.scribd.com/doc/222400050/The-Secret-That-Doubles-Testosterone

Iodine protocol

We still got to find a basic PBI protocol.

I have noted a few supplements but want to find something more conclusive.

It usually involves HRT but I am hoping a kickstart with the basic supplements plus the iodine protocol might be all that is needed.

NAC is a precursor toglutathione and i think that this might be needed as part of any protocol.

GLUTATHIONE OVERVIEW INFORMATION

The very frst post on this huge thread..he states these symptoms:

Dry Eyes (Severe)

- E.D/ Low Libido (Started last year and has gone on consistently since)

- Hair-loss (Including eyebrows, facial hair 'gaps' and body hair)

- Slow Healing (Shaving is a pain now - No, it's not my technique)

- Lack of sebum (oil)

- Brain Fog/ Memory problems - Somewhat minor

- Anxiety (mainly because of the other side effects - i.e. dry eyes causing me to feel embarassed about eye contact)

- Excessive hair (Not related to head, but my beard grows high up on cheeks and even on the outside of my nose)

- I believe I look older than I should due to lack of oil

- Joint/Muscle problems - Aches/ Slow recovery

- Excessive sweating.. Terrible if I go running at the gym, for example.

- Dry mouth

- Nosebleeds more than I should

- Fatigue

These are ALL mimics of iodine deficiency and hypothyroidism.

The effects of vitamin A on thyroid hormone production and action have been known for many years. In the 1940s, Simkins demonstrated that patients with hyperthyroidism, were successfully treated with high dose of vitamin A (1) . When treated with vitamin A, these hyperthyroid patients had decreased symptoms of hyperthyroidism as well as decreased metabolic rate. Shadu and Brody studied this effect in euthyroid rats which were fed 30,000 IU of vitamin A per day for 7 days (2). The vitamin A fed rats had a 10% decrease in oxygen consumption and interestingly were found to have a 35% decrease in thyroid weight. The authors hypothesized that vitamin A suppresses pituitary thyrotropic hormone secretion thereby decreasing thyroid hormone production and oxygen consumption. This was the first suggestion that large doses of vitamin A may be affecting thyroid hormone production and function through a central mechanism

All of these could be related to Iodine uptake problems. research NIS transporters and retinoids Vitamin A and or retionids could be covering the goiter problems, but affecting every other system. We could have a NIS transporter problem after accutane that stops the iodine from entering the cells.

The impact of retinoids on the thyroid axis
http://www.eje-online.org/content/170/6/R253.full.pdf

http://ajcn.nutrition.org/content/86/4/1040.full

Vitamin A supplementation in iodine-deficient African children decreases thyrotropin stimulation of the thyroid and reduces the goiter rate1,2,3

and.....

am being treated with Bexarotene and my thyroid stopped working. What is going on?

Bexarotene is a synthetic retinoid X receptor (RXR)-selective retinoid used in the treatment of cutaneous T-cell lymphoma. Bexarotene causes hypothyroidism by reducing levels of both thyroid-stimulating hormone (TSH) and thyroxine, and treatment may require relatively high levels of thyroxine. SeeEtiology, diagnosis, and treatment recommendations for central hypothyroidism associated with bexarotene therapy for cutaneous T-cell lymphoma. Clin Lymphoma. 2003 Mar;3(4):249-52.

and.....

Effects of retinoids on iodine metabolism, thyroid peroxidase gene expression, and deoxyribonucleic acid synthesis in porcine thyroid cells in culture.

So is this stating that thyroid medications wouldn't have an effect then?

Before we get too carried away here. 37 percent of the recommended daily intake of iodine is in one cup of milk. Just one cup. Is the American diet pretty low on Salt these days?

You can reference your thyroid TSH levels here.

https://www.endocrineweb.com/conditions/hypothyroidism/hypothyroidism-diagnosis

• 0.4: normal
• 2.5: at risk
• 4.0: mild hypothyroidism
• 10.0: hypothyroidism.

Today's TSH tests are very accurate and sensitive; they can help diagnose even the mildest cases of hypothyroidism.

What are you getting at..?

like KSman asks people in the TRT thread...go by symptoms.

1. what is your temperature throughout the day? low?
2. what is your resting heart rate? low?
3. did you lose the hair around your ankles and shins after accutane?
4. do you have cold extremities...hands and feet?
5. have you been tested for the MTHFR 677T mutation (two from this thread are homozygous yetanotheraccutane victim and movingonmusicgal)

In a pm from movingon.... she had total joint pain relief from 25 mg a day of lugols iodine)

its very important to take selenium before trying high doses of lugols. Also very important to work your way up. 1 drop 2 drops 3 drops etc of 2% lugols... until you get to 10 (25mg)

active forms of the cofactors would be best in case of a polymorphism i.e. riboflavin 5 phosphate instead of the generic b2.

in theory the lugols should help you produce t4...then the cofacors are needed to convert it to t3 and also mop up any ROS along the way.

read all of the comments from lugols on amazon . kind of crazy.

PFS anecdotes

http://www.propeciahelp.com/forum/viewtopic.php?t=6521