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8 minutes ago, ehohel said:Yeah my ibudilast came in today, I feel shot awake on it, going to see if it gets better with continuous use. And I'm gonna continue the memantine, might as well as I already have it.
Great, I may actually wait until allergy season to try it since Ibudilast is supposed to help with that too. I bought Memantine a year ago, but was too scared to try it. I have actually heard of people getting stuck in that brain fog phase long after quitting the drug. That's obviously rare, but my experience with Accutane makes me take fringe anecdotes more seriously than I once did. I'm still tempted to take the plunge though. Let me know how it pans out.
2 hours ago, ACCUiTy_drANE said:Great, I may actually wait until allergy season to try it since Ibudilast is supposed to help with that too. I bought Memantine a year ago, but was too scared to try it. I have actually heard of people getting stuck in that brain fog phase long after quitting the drug. That's obviously rare, but my experience with Accutane makes me take fringe anecdotes more seriously than I once did. I'm still tempted to take the plunge though. Let me know how it pans out.
Will do, I'm in a pretty good place right now, I think anastrozole really did fix basically everything for me, and anything else I'm trying right now is just to try and further enhance my life.
Hello.
I noticed big improvements with 5gr day creatine for ED, Creatine and L-Carnitine are best supplement that i've found in these years. I see that Zink is one of the most popular supplement but Zink worsened seriuosly my sides. with creatine sebum return in my face, with zink my face is dry, inexistend sex drive and p***s death, what does it mean?
Next I would test Iodine and Calcium d-glucarate, these are new for me but i think can help my condition with sexual problems, no weight gain and muscle loss that I experienced after accutane.
8 hours ago, Ruvik said:Hello.
I noticed big improvements with 5gr day creatine for ED, Creatine and L-Carnitine are best supplement that i've found in these years. I see that Zink is one of the most popular supplement but Zink worsened seriuosly my sides. with creatine sebum return in my face, with zink my face is dry, inexistend sex drive and p***s death, what does it mean?Next I would test Iodine and Calcium d-glucarate, these are new for me but i think can help my condition with sexual problems, no weight gain and muscle loss that I experienced after accutane.
My cock can literally cut diamonds after a few days ofanastrozole.
12 hours ago, Ruvik said:Hello.
I noticed big improvements with 5gr day creatine for ED, Creatine and L-Carnitine are best supplement that i've found in these years. I see that Zink is one of the most popular supplement but Zink worsened seriuosly my sides. with creatine sebum return in my face, with zink my face is dry, inexistend sex drive and p***s death, what does it mean?
Seems some have high DHT and respond well to zinc, and things that are a good source of zinc (i.e. pumpkin seeds). I'm in this group. Others have low DHT and respond well to things that raise it, namely creatine. Not sure if you've had bloods done, but presumably you'd have low DHT.
I've just got some sustain alpha so I'm going to see if that helps. It should raise LH and FSH (as it blocks E2), and I'm low with those and in turn lower SHBG (mine is high-ish), and that will increase free testosterone.
On 30.12.2016 at 10:09 PM, Nicholas Ross said:Your hair loss could be due to stress.
It is different. My hair thinned and I can clearly say the texture of my hair changed. I lost lots of my hair too.
It is a side effect of Accutane.
"According toWebMD, there are two types of hair loss induced by medications: telogen effluvium and Anagen effluvium. Typically, a healthy hair passes through two phases of growth: the anagen phase and telogen phase. The anagen phase is the period of continuous hair growth, and it lasts for three to four years. Following that it enters the telogen phase, which lasts about three months a period of rest. At the end of the telogen phase, the hair falls out and is replaced by a new hair.
Telogen effluvium is the most common type of drug-induced hair loss. In this, the patient starts losing hair within two to four months after taking the drug. The drug causes the hair follicles to go to the telogen phase and fall out too early. Typically patients suffering from this type of hair loss shed 100t o 150 hairs a day.
Most common drugs that induce Telogen effluvium include Vitamin A drugs containing retinoids, antibiotic and antifungal drugs, antibiotics and antifungal drugs, antidepressants, birth control pills, epilepsy drugs, drugs that treat high cholesterol and high blood pressure, anti-clotting drugs, nonsteroidal anti-inflammatory drugs (NSAIDs), and Parkinsons disease drugs."
http://www.hairfear.com/hair-loss/21-understanding-drug-induced-hair-loss.htm
Hello to any fellow Accutane users,
I am wondering if many people out there have had their gut bacteria looked at or tried a 10 day antibiotic course of metronizadole and paromomycin?
Alot of lawsuits over Accutane have been to do with gut health. It seems that a 10 day antibiotic course is a very simple thing to try.
Anyone else out there apart from the two guys Ive come across in the threads?
Thank you for your time,
MoreTwine
Interesting conversation I cam across.
https://raypeatforum.com/community/threads/idealabs-recommendation-overcoming-post-ssri-sexual-dysfunction.14449/
12 hours ago, hatetane said:Interesting conversation I cam across.
https://raypeatforum.com/community/threads/idealabs-recommendation-overcoming-post-ssri-sexual-dysfunction.14449/
Good spot, that threads worth keeping an eye on, some interesting points made on there!
15 hours ago, MoreTwine said:Hello to any fellow Accutane users,
I am wondering if many people out there have had their gut bacteria looked at or tried a 10 day antibiotic course of metronizadole and paromomycin?
Alot of lawsuits over Accutane have been to do with gut health. It seems that a 10 day antibiotic course is a very simple thing to try.
Anyone else out there apart from the two guys Ive come across in the threads?
Thank you for your time,
MoreTwine
I haven't heard of these 2 antibiotics till now. My specialist who I just finished up with had me on Rifaximin & Vancomycin for 3 months, did nothing really other than I had less stomach aches during this time.
Please, if you know of lawsuits etc from Accutane/stomach issues pls post links - this would be very helpful as I could share with specialist.
He dismissed my case ruling out anything sinister but I know my gut health just isn't completely right. I'll be very pissed off if those 2 you've mentioned were to work and he didn't think to put me on those next.
Why specifically did you bring them up? Do you know if Accutane victims have successfully used them??
Thx for info.
2 hours ago, TrueJustice said:Please, if you know of lawsuits etc from Accutane/stomach issues pls post links - this would be very helpful as I could share with specialist.
The above link discusses how these lawsuits brought to light evidence of clinical trials and patient memos, which helped to demonstrate a causal link between Accutane and IBD. Accutane appears capable of damaging the intestinal lining. Even Roche acknowledged Accutane's capability to do this, but they backpedaled as time went on. Note how the article talks about how sometimes issues arise after quitting treatment. Unfortunately, these clinical trials are not in the public domain. However, it is common practice for drug companies to suppress clinical trials that yield unfavorable results, as half of all clinical trials are not published and 80% of clinical trials are outright fabricated in China. This context is important to provide before talking about Accutane specifically, as people need to be aware that this is a systemic problem that happens to be relevant to Accutane as well.
Also, be sure to show your specialist this study:
http://www.ncbi.nlm.nih.gov/pubmed/22239608
"Systemic isotretinoin and antibiotic treatments in acne patients precisely caused variations in the microbial floras of several sites of the body, while isotretinoin was commonly more responsible than antibiotics."
In regards to the correlational studies done that examined the link between Accutane and IBD, many failed to find a link. That is because they are utter TRASH. For example, in one I looked at, the proportion of Accutane users who developed IBD on Accutane was LESS than the general population, which almost implies a protective characteristic of Accutane. These skewed numbers are EASILY explained by under-reporting and the delayed onset of the disease, which the study fails to acknowledge. For the issue of depression and suicide, it is estimated that actual instances of these side effects are 10 times higher than what is reported. For the issue of IBS and IBD, there is obviously something similar going on as well. Multiple sources acknowledge that actual reported adverse drug events need to be multiplied in order to reflect the actual numbers.
All that being said, I repeat that LDN and Magnesium Citrate have been a godsend in managing post-Accutane IBS.
2 hours ago, TrueJustice said:I haven't heard of these 2 antibiotics till now. My specialist who I just finished up with had me on Rifaximin & Vancomycin for 3 months, did nothing really other than I had less stomach aches during this time.Please, if you know of lawsuits etc from Accutane/stomach issues pls post links - this would be very helpful as I could share with specialist.
He dismissed my case ruling out anything sinister but I know my gut health just isn't completely right. I'll be very pissed off if those 2 you've mentioned were to work and he didn't think to put me on those next.
Why specifically did you bring them up? Do you know if Accutane victims have successfully used them??
Thx for info.
http://www.propeciahelp.com/forum/viewtopic.php?f=1&t=10897
I found one case for you Truejustice
Thx for info - I definitely know about the bowel lawsuit cases, I did want to know however if there were stomach issue lawsuits specifically. You'd have to assume though that anyone with bowel issues surely would have some gut issues going on too.
I'm at the point where I should just print off every bit of info on negative Accutane issues, put it all in a massive file and take it with me to any doctor or specialist ready to retrieve when I get a nauseating/ignorant response. "Oh you've never heard of roaccutane causing that have you?"
Well let me show you something from my file idiot - fuckn specialist my arse.....
Please share again your benefits of LDN? Is there less fatigue, does your body feel strong with less stiffness etc. How does it affect depression?
Also with regard to telomere shortening which someone mentioned getting a test recently indicating they were indeed shortened, how do we reverse this?
Are all the things that people are advocating lately doing anything to fix telomere length or is this telomere theory just bullshit and not worth investigating?
Thx
30 minutes ago, hatetane said:http://www.propeciahelp.com/forum/viewtopic.php?f=1&t=10897
I found one case for you Truejustice
Thx mate - much appreciated:)
Hi TrueJustice,
Try this link
[Edited link out]
I think it was posted on this forum somewhere too.
I'm not aware of any specific gut issues myself but my cousin has had a bunch of problems since taking Accutane. Gas, bloating, cramps, weight gain, struggles to poo. My thoughts are if it effects the gut it may effect the mind. Look into the gut-brain connection. For myself I think I would like to go get my gut flora checked. Other option is really antidepressants for me.
As for lawsuits I am no expert but again if you do some googling you will see that there have been several court cases in the US (Chrohn's/IBD). As for the outcomes of those cases I'm not exactly sure. It certainly puts some sincerity into the argument though.
I understand your pain and frustration with doctors. I have had similar experiences. My view is not to take it out on them; this is a much bigger issue then them - something they have not studied for or learnt in textbooks. We need to get doctors on our side and make change in the pharmaceutical industry.
The reason I brought them up is simply because I read about them. Out of all of the different treatment theories I have read this one seemed quite easy to try and it aligned with one of my own personal theories. The two reports that I found seemed very positive, almost too good to be true though. Low risk to give it a try but.
On 1/3/2017 at 10:15 AM, MoreTwine said:Hi TrueJustice,
Try this link
[Edited link out]
I think it was posted on this forum somewhere too.
I'm not aware of any specific gut issues myself but my cousin has had a bunch of problems since taking Accutane. Gas, bloating, cramps, weight gain, struggles to poo. My thoughts are if it effects the gut it may effect the mind. Look into the gut-brain connection. For myself I think I would like to go get my gut flora checked. Other option is really antidepressants for me.
As for lawsuits I am no expert but again if you do some googling you will see that there have been several court cases in the US (Chrohn's/IBD). As for the outcomes of those cases I'm not exactly sure. It certainly puts some sincerity into the argument though.
I understand your pain and frustration with doctors. I have had similar experiences. My view is not to take it out on them; this is a much bigger issue then them - something they have not studied for or learnt in textbooks. We need to get doctors on our side and make change in the pharmaceutical industry.
The reason I brought them up is simply because I read about them. Out of all of the different treatment theories I have read this one seemed quite easy to try and it aligned with one of my own personal theories. The two reports that I found seemed very positive, almost too good to be true though. Low risk to give it a try but.
Thx MoreTwine but I need more detail pls, post the links to those who've had success using the 2 antibiotics you mentioned on treating the gut specifically!!
Also, if you know how a doctor/specialist knows how to look in detail at ones specific gut health pls let me know????
Sure enough they can do a castroscopy to check for disease etc which I had done back in June - nothing sinister BUT tell me how the can test your flora and gut lining???? To my knowledge they can't be that specific!?
I do know that with "Iridology" they can tell if your gut health is good or bad but again they can't conclude what/if you need antibiotics and which ones!!??
So if you know of any "Gut Health" test that we're unaware of pls let us know.....
cheers.
http://www.freepatentsonline.com/5861389.html
Back to estrogen
On 1/2/2017 at 5:56 PM, TrueJustice said:Please share again your benefits of LDN? Is there less fatigue, does your body feel strong with less stiffness etc. How does it affect depression?
Yeah, my pain symptoms are intermittent, but I haven't had much issues since LDN. I do have more mental energy, although I never had an issue with physical energy. Self-Hacked's article on LDN is my favorite, as you can navigate the page to learn about LDN's impact on the symptoms you're interested in. Long story short, LDN appears capable of helping depression because it manages inflammation in the body. Every immune system cell has receptors for endorphins and enkephalins, therefore LDN's ability to boost production of endorphins, as well as sensitize these receptors, is highly significant. Circling back to pain, LDN has been proven effective to treat several different kinds of pain, including pain from arthritis. The studies are included in the link.
On 1/2/2017 at 5:56 PM, TrueJustice said:Also with regard to telomere shortening which someone mentioned getting a test recently indicating they were indeed shortened, how do we reverse this?
Are all the things that people are advocating lately doing anything to fix telomere length or is this telomere theory just bullshit and not worth investigating?
In theory, a peptide known as Epitalon can increase telomere length. The telomere angle will always interest me because we already have rock solid evidence that Accutane causes apoptosis (cellular death) all over the body, including muscle, bones, and brain. We also know Accutane's metabolite can cause telomere shortening by down-regulating the telomerASE enzyme. (What we don't know it how active the metabolite really is.) Why does telomerASE matter? Because it plays a role in repair functions via adult stem cells and some evidence suggests telomerase dysfunction (begin reading at: "The relevance of telomere shortening induced by dysfunctional telomerase") can cause a wide array of issues. So there are two pieces of evidence that show telomerASE plays a role in more than just exacerbating cancer. Perhaps Accutane screws with normal stem cell operations, which explains why the side effects tend to be delayed, chronic, vague, etc. Our bodies still work, just not as efficiently. On an intuitive level, this angle makes total sense to me.
Thx for the detailed info ACCUiTy.
Can I asked though, what are your thoughts on working on gut health by addressing with antibiotics? What if that's the key - the whole gut/brain relationship.
I just can't help but think that the gut is the first thing that cops damage when taking tane and as much as I want to work on having less brain fog, better sleep and clarity etc, I just don't think we should overlook gut issues as being the main problem here. Sure some of the things mentioned on this forum will help with brain issues but are we really addressing the main problem by overlooking gut health....I don't know.
Keen I know what you and others think?
Just linking this again for any newcomers.
http://www.protocol-online.org/forums/uploads/monthly_08_2010/msg-19273-027408800 1282061244.ipb
This maybe worth printing and taking to your GP (good luck trying to get them to listen)
9 hours ago, hatetane said:Just linking this again for any newcomers.
http://www.protocol-online.org/forums/uploads/monthly_08_2010/msg-19273-027408800 1282061244.ipbThis maybe worth printing and taking to your GP (good luck trying to get them to listen)
Thank you for reminding me. I've printed it and will present the document to my Andrologist on Jan 30th. This gives me more confidence that going on Androgel would not help me. Now that I know for certain I have low T, LH and FSH.. this kind of gives reason to this whole document.
I had never looked up the propheciahelp website as I thought it may not give me accurate information seeing as I didn't take Finasteride, but reading this right now today.. this is exactly in line with my conclusions from 6 months of experiment. I'm going to keep working on this.
[Edited link out]
6 hours ago, Kynarr said:Thank you for reminding me. I've printed it and will present the document to my Andrologist on Jan 30th. This gives me more confidence that going on Androgel would not help me. Now that I know for certain I have low T, LH and FSH.. this kind of gives reason to this whole document.
Can you ask ( not in a rude way )
why it takes us to have to print off such a document and bring this stuff to their attention??
Why don't they know???
If we didn't rock up with this, we'll prob only get the same dismissive response I'd imagine.....mind boggling!!!!
Its good ammunition this document - let's use it!!!
1 hour ago, TrueJustice said:Can you ask ( not in a rude way )
why it takes us to have to print off such a document and bring this stuff to their attention??Why don't they know???
If we didn't rock up with this, we'll prob only get the same dismissive response I'd imagine.....mind boggling!!!!
Its good ammunition this document - let's use it!!!
I'm 99% confident she doesn't speak english and won't even get to read anything I provide her. This is Quebec City. Very conservative, very old, very close-minded... very dumb. I'm not luring myself, I expect nothing from bringing this except convince myself she's unfit to help.
On 01/04/2017 at 0:13 AM, TrueJustice said:Can I asked though, what are your thoughts on working on gut health by addressing with antibiotics? What if that's the key - the whole gut/brain relationship.I just can't help but think that the gut is the first thing that cops damage when taking tane and as much as I want to work on having less brain fog, better sleep and clarity etc, I just don't think we should overlook gut issues as being the main problem here. Sure some of the things mentioned on this forum will help with brain issues but are we really addressing the main problem by overlooking gut health....I don't know.
Yeah, I think the mind-gut connection is incredibly interesting. You have probably already read the article themselves, but we have literally cured devastating diseases in mice (e.g., Parkinson's) by transplanting certain gut bacteria from diseased mice to healthy mice. We can make a mouse obese by transplanting gut bacteria from an overweight mouse to a healthy mouse, even if diet remains the same. If you Google "gut flora, mice, depression" you'll see similar studies with depression. Depression and cognition are dictated by biological forces just like any other disease, and the role of the microbiome cannot be overstated. The problem is that we don't have equally precise methods of altering microbiome in humans as we do mice. Anything that enhances the immune system probably positively influences the microbiome in some way, and vice versa. That's why I wouldn't immediately write-off anything that ISN'T probiotics/prebiotics/dietary. And that's why LDN appeals to me.
That being said, if you want the best shot of healing of your gut, I think it would be smart to eliminate all of the following: Grains, processed sugars, nightshades, and lectin. Furthermore, total carbohydrate intake should probably be no higher than 100-150 grams, regardless of the source. I recently read many studies that suggest all of the aforementioned foods can increase inflammation. Even non-gluten grains can aggravate inflammation/allergies, because the immune system sucks at differentiating similar-looking proteins once the sensitivity is acquired! Unfortunately, I haven't yet mustered the willpower to implement such a strict diet.