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How old are you out of curiosity? Have you shown hair loss at all before supplementing?
The body is complicated. I just was explaining one example of the possible interactions that caused it.
I'm 19 now, was 17 when I took it. Never had hair loss or shedding before. I had very nice full hair before. After 1 week of B5 it was like a switch was turned and my hair started to shed dramatically. 90% of my hair loss is around the hairline. Generally I only shed in androgen-sensititive areas.
I don't take a B-Complex but my multivitamin contains all the B-vitamins (including B5). It's 50mg. Not sure if it has sped up my hair loss though. It contains a lot of other important nutrients that support healthy hair.
As for minox/RU, no I haven't tried either. I have some Minox lying around the house but I'm hesitant to use it. It doesn't work too well on the hairline and there is a decent chance it will make your hairline worse permanently as the hairs/follicles there are so sensitive. I'm putting off on Minox until I have hair loss all over my head and not just on the hairline.
Also it can cause dark circles under the eyes which I already have thanks to Propecia. I took that stuff for 3 weeks and I'm still experiencing minor side effects 5 months later. I'd seriously suggest everyone to avoid Finasteride. It's just hair, it's not worth it
me too elemachanico, three days of about 7 tablets, then 2 days of about 3 tablets, and for a whole year now- incredibly shedding. It's crazy what you get semi used to I guess but its still a daily confidence decreaser 
it annoys me that there must be some way of reversing it but we will never be able to figure it out.
This is possibly the biggest mistake I've ever made. I've receded sooo much it's incredible. And to find out that there hasn't been a single person who's experienced regrowth is extremely depressing.
Hermetics and discomfortzone reversed their hair loss. Take another read, if you start taking colostrum at 10g + per day, and thyroid supplements you might surprise yourself, my hair is currently growing.
This is possibly the biggest mistake I've ever made. I've receded sooo much it's incredible. And to find out that there hasn't been a single person who's experienced regrowth is extremely depressing.
Hermetics and discomfortzone reversed their hair loss. Take another read, if you start taking colostrum at 10g + per day, and thyroid supplements you might surprise yourself, my hair is currently growing.
Thanks man. So your hair has started growing back as well? I'm now taking colostrum 10g+ a day and Raw Thyroid. Is it fine to take more than 1 pill a day?
SMVT is the protein that is responsible for the metabolism of biotin and pantothenic acid. [1] Conversely, the regulatory aspects with the sodium-dependant multivatmin transporter is mediated by the direct intracellular concentration of biotin causing an internally allosteric regulation. The biotin concentration is directly related to the expressed transduction activity of the active transporter. [2]
Now having a supraphysiological concentrations of only one key vitamin(s) that directly rely on the gene expression controlling the transduction activity can produce a chromatin-mediated remodeling that leads to cell receptor internalization. [2] The regulatory actions of SMVT is thought to be mediated by a DNA binding factor belonging to the transcription factor family. [3]
Just like the synergistic/antagonistic nature associated with trace mineral absorption for example zinc and copper metabolism. Having a supraphysiological concentration of one trace mineral without the other causes a compartmental displacement leading to diminished interactions from their respective metalloprotein transporter. [4] (Zinc and copper molecules both rely on the same metalloproteinase enzyme as a catalyst for absorption)
So here is everything summed up. Abnormal concentration of pantothenic acid could have caused endocytosis-mediated cell internalization. This means that the subsequent upregulatory actions from the supraphysiological presence of a vitamin is mitigated once the need for additional proteinase is unnecessary. The cellular biomechanical activity with B5 predominantly accounts for most of the enzyme activity and this leads to the displacement of the lesser vitamer causing a lower affinity for coupling to the ligand. The body undergoes degredation of the receptor site (a protein) and eventually undergoes the recycling of cellular receptors called endocytosis. (lysosomal digestion within the organelle golgi apparatus is the final step)
The gene that is coincidentally labeled as a "major involvement" is known as the SLC5A6 gene. [5][6]
Biotin deficiency can cause brittling of the hair. Conversely, biotin concentration is a contributing factor to the regulatory actions that control the transporter's receptor density.
[1] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406285/
[2] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606921/
[3] http://ajpcell.physiology.org/content/292/4/C1305.long
[4] http://www.traceelements.com/Docs/Nutrient%20Interrelationships-Minerals-Vitamins-Endocrines.pdf
[5] http://www.ncbi.nlm.nih.gov/gene/8884
[6] http://www.ncbi.nlm.nih.gov/pubmed/25809983
I feel I supplied enough reference material for my proposed theory of micronutrient-induced deficiency leading to acute hair loss. I don't spew statements without having a conscientious acknowledgement that I feel I adequately possess sufficient sourcing material. I'm open to challenging the plausibility of any other contradicting information provided. I usually don't get this technical, but if someone feels that information is being circulated without representation than I'll satisfy their beckoning.
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DHT related side effects expressed by the high affinity for androgenic activity is generally a more gradual contributor to hair loss. Doesn't mean a rapid shedding incident has never happened, but the affinity for producing these side effects relies on the hormone's concentration that is directly mediated by the 5au-reductase enzyme. This is responsible for being the catalyst associated with testosterone>dihydrotestosterone conversion.
To the member asking about B-Complex usage, I have used an I.M form of the B-Complex for years now. The most effective route leading to the highest bioavailability and diminished incidences with malabsorption/vitamer degration is either intramuscular, subcutaneous, or in bizarre solutions some nutrients can be successfully introduced via intravenous. I don't recommend this practice though to everyday people.
-To Bashido,
Members here can gladly ignore my personal advice about using DHT antagonists. I'm just another user trying to help others and everything on the internet should be taken with a grain of salt. With that said I can attest to my reputable knowledge that I've accrued over the years in the field of pharmacology. I'm also highly versed on the activities in our endocrine system in comparison to the majority of contributors.
I know for a fact that the steroidal inhibitors generally used for DHT inhibition produces a great deal of undesirable side effects. The 5au-reductase enzyme not only is a catalyst for testosterone>dihydrotestosterone conversion, but also reduces the effective inhibitory activity on the GABA receptors. (GABA is a neurotransmittor that affects sexual desire, alcohol response, brain development. also has an antidepressant mechanism along with a few others..)
Most don't know the extent of inhibitory activity with their ointment. (3 isoenzymatic contributors. some inhibit 2 out of 3 for a partial inhibitory response while others inhibit the activity of all 3 5au-reductase isoenzymes) They aren't suicide inhibitors resulting in irreverisble modulation to the receptor, but the extent at which the expression continues to function can take at times 4-6 months. Receptor internalization/alteration can be a slow process. Gene transcription is rate limited by transcripting factors as well as extracellular signal transduction mechanics.
This is possibly the biggest mistake I've ever made. I've receded sooo much it's incredible. And to find out that there hasn't been a single person who's experienced regrowth is extremely depressing.
Hermetics and discomfortzone reversed their hair loss. Take another read, if you start taking colostrum at 10g + per day, and thyroid supplements you might surprise yourself, my hair is currently growing.
Thanks man. So your hair has started growing back as well? I'm now taking colostrum 10g+ a day and Raw Thyroid. Is it fine to take more than 1 pill a day?
Always ask your doctor, I am not taking raw thyroid currently, I am taking Now Thyroid Energy. My hair has been growing, but I am still losing hair every day 
-To Bashido,
Members here can gladly ignore my personal advice about using DHT antagonists. I'm just another user trying to help others and everything on the internet should be taken with a grain of salt. With that said I can attest to my reputable knowledge that I've accrued over the years in the field of pharmacology. I'm also highly versed on the activities in our endocrine system in comparison to the majority of contributors.
I know for a fact that the steroidal inhibitors generally used for DHT inhibition produces a great deal of undesirable side effects. The 5au-reductase enzyme not only is a catalyst for testosterone>dihydrotestosterone conversion, but also reduces the effective inhibitory activity on the GABA receptors. (GABA is a neurotransmittor that affects sexual desire, alcohol response, brain development. also has an antidepressant mechanism along with a few others..)
Most don't know the extent of inhibitory activity with their ointment. (3 isoenzymatic contributors. some inhibit 2 out of 3 for a partial inhibitory response while others inhibit the activity of all 3 5au-reductase isoenzymes) They aren't suicide inhibitors resulting in irreverisble modulation to the receptor, but the extent at which the expression continues to function can take at times 4-6 months. Receptor internalization/alteration can be a slow process. Gene transcription is rate limited by transcripting factors as well as extracellular signal transduction mechanics.
You spelled my name wrong, I never mentioned anything about side effects, I was challenging your statement on the efficacy of DHT inhibitors to combat this problem. I would never recommend anyone to take a DHT inhibitor. Alas, you are making these long posts on the assumption that this problem follows a typical paradigm / makes logical sense. This problem does not make any sense whatsoever, and its not biotin related either, I guarantee nobody here is deficient in biotin, and I can strictly state I was taking biotin with my b5 and am not deficient. If this problem was relevant to an obvious vitamin deficiency, this forum thread would have died long ago...
Long time since I've been on this thread (or indeed this site) but it seems very few people have had any success with their hair loss since I was last here. For the past few months I've been reluctant to take the Finasteride tablets provided by my doctor but I've decided that i'll start in the next week. The success rate differs from differs from person to person, with lots of success/horror stories but I really feel this is probably the only shot at curing baldness....either that or a super expensive hair transplant (e.g wayne rooney style) 
)
The reviews from my one are spot on and you can book appointments with her too. Mike u got my email stay I'm touch bro. Need to come off here now.
Hey man, not sure if you still come here but I was just wondering if those supplements were helping? There's a been a lot of theories and suggestions in this thread that haven't panned out but the plan your lady suggested sounds promising
The reviews from my one are spot on and you can book appointments with her too. Mike u got my email stay I'm touch bro. Need to come off here now.
Hey man, not sure if you still come here but I was just wondering if those supplements were helping? There's a been a lot of theories and suggestions in this thread that haven't panned out but the plan your lady suggested sounds promising
Hey bud yeh your right I try not to come on here anymore had to give up, most people on here are just obsessed with it being dht so I just can't be bothered to argue anymore. Anyway yes mate my hair is the best it's ever been atm I'm still shedding hair but it's definitely thicker and fuller, also at the front of my hairline there are hairs coming through not sure if it's normal hair cycle or regrowth but there very noticeable as my hair is about 5inches long and these hairs are about 1 inch now, anymore questions bud just private message me because I can guarantee some idiot will say I'm lying haha. Take it's easy bud.
Ok thanks Blue09. Please keep us updated on your hair loss results.
In a previous post I stated when I received the results back from my endocrinologist, she told me my thyroid looked fine but there was an incident years back where it had issues. I guess she could view the timeline of my thyroid from the results. She did say that incident shouldn't have any effect now but I did not see the test results. I was suppose to go back a few months ago to be retested and I will soon.
I have started Detoxadine and Liquid selenium. Will see if this helps and will have tests done to insure it is not messing up my thyroid system.
This is possibly the biggest mistake I've ever made. I've receded sooo much it's incredible. And to find out that there hasn't been a single person who's experienced regrowth is extremely depressing.
Hermetics and discomfortzone reversed their hair loss. Take another read, if you start taking colostrum at 10g + per day, and thyroid supplements you might surprise yourself, my hair is currently growing.
MrBushido, so you're taking NOW Thyroid energy? Looks like this and raw thyroid supplements all contain selenium and iodine (which is what Detoxadine is). Hopefully we are on to something. Thanks!
Thought I'd check in real quick.
It's now been exactly 2 years since my little B5 adventure started.
My hair has slowly but progessively thinned out in the temples over that time period.
I still have a lot of hair everywhere else but my hairline is getting worse.
I feel like I still have some vellus hair where my hairline used to be so that gives me hope and makes me think I'd be a good candidate for Minoxidil.
Overall my hair is now a bit darker than before and also often dry. My hair used to be blonde and shiny in comparison.
I currently use a pretty big list of supplements including Biotin, iodine, Cysteine and selenium. Also use aloe vera and some oils on my hair and scalp.
Shedding seems to have normalized, I think I lose an average amount of hair a day. I don't count the hairs but I don't notice excessive hair fall either.
This is possibly the biggest mistake I've ever made. I've receded sooo much it's incredible. And to find out that there hasn't been a single person who's experienced regrowth is extremely depressing.
Hermetics and discomfortzone reversed their hair loss. Take another read, if you start taking colostrum at 10g + per day, and thyroid supplements you might surprise yourself, my hair is currently growing.
MrBushido, so you're taking NOW Thyroid energy? Looks like this and raw thyroid supplements all contain selenium and iodine (which is what Detoxadine is). Hopefully we are on to something. Thanks!
I stopped and switched to selenium, zinc, iodine, it was making me tired (first pill, second pill i felt fine) and felt nauseous sometimes from it. Already take ashwagandha (excuse spelling) seperately too.
Thought I'd check in real quick.
It's now been exactly 2 years since my little B5 adventure started.
My hair has slowly but progessively thinned out in the temples over that time period.
I still have a lot of hair everywhere else but my hairline is getting worse.
I feel like I still have some vellus hair where my hairline used to be so that gives me hope and makes me think I'd be a good candidate for Minoxidil.
Overall my hair is now a bit darker than before and also often dry. My hair used to be blonde and shiny in comparison.
I currently use a pretty big list of supplements including Biotin, iodine, Cysteine and selenium. Also use aloe vera and some oils on my hair and scalp.
Shedding seems to have normalized, I think I lose an average amount of hair a day. I don't count the hairs but I don't notice excessive hair fall either.
Well this is certainly scary, i hope you just recently started the thyroid ones. Not sure why your hair is still dry if you're using oils on your scalp...
Quick update: Been using Iodine, biotin, cysteine, calcium, magnesium, zinc and multivitamin(with a lot of B-vitamins) for a couple of weeks now. My hair quality is definitely better. More shine, softer and just like it was before B5. I buzzed my head twice in the last 4 months and I think it really helped my scalp issues. My scalp was finally able to breathe. I only used shampoo sparingly and lathered my head in aloe vera and different oils. I'd recommend that to a lot of the guys here.
Anyway, it looks like I might be seeing beginning stages of regrowth on my temples. Can't say for certain yet. I will continue with the supps. Also have some colostrum coming in.
Other stuff I've been doing:
-scalp massage every day with one of those prick-ly scalp massage thingies(you know the kind, the one that feels amazing when somebody uses it on you)
-brush hair every day
-use oils to nourish hair and aloe vera gel to calm the scalp and increase cell turnover at a molecular level. Also fights off inflammation.
-dermaroll once a week
-ACV rinse on scalp and drinking ACV every 2nd day
-no alcohol, caffeine, weed etc. basically no bad influences on health. No fast food. Minimal dairy(only in my protein shakes)
-more veggies and fruit in diet
I'm cautiously optimistic at the moment. Also have some colostrum and collagen coming in, curious to see how I fare on those.
Edit: Forgot to mention, shedding is down a lot too. Scalp problems are completely gone. I know that I posted here on Saturday as well but since then my hair has been better every day.
What's really important too is adequate sleep and not stressing about the hair. I use deep breathing, stretching, yoga and exercising to take my mind of things. When I buzzed my hair I was the happiest I had been in months. People said it suits me too. It's really refreshing to not have to worry about your hair.