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Caloric Intake and Acne

How Changes in Caloric Intake Can Hypothetically Influence Acne

Last updated: December 20, 2018

Article Summary

Why do so many "acne diets" seem to work only temporarily? The answer may be quite simple. Decreasing calories may help clear acne in the short term, while increasing calories may make acne worse in the short term. So, that "acne diet" you were on might have worked at first because removing supposed "bad" foods really just meant you initially lowered your calories. When you started eating normally again the acne most likely reasserted itself.

Since we can't go low-calorie forever, the smartest way to eat is to consume sensible portions of low glycemic (low sugar), whole foods alongside colorful fruits and vegetables when you can. In other words, eat healthy to support your skin instead of chasing that miracle "acne diet."

Note: Even though going low on calories might help clear up the skin in the short term, it is unhealthy to do this long term. It is much better to eat an adequate amount of healthy foods than it is to restrict calories.



There is a growing body of scientific evidence to support the idea that diet and acne may be, at least in part, connected. Perhaps the most overlooked dietary factor that may affect acne development is a person’s caloric intake. 

Research has shown that a high calorie diet affects hormones that are associated with acne, hypothetically leading to more acne. On the flip side, lowering calories might have the opposite effect.

So when people eliminate foods they heard were bad for acne, their acne may improve, and they may give credit to the "acne diet" they are on for their clearer skin, when in fact, they are simply inadvertently reducing their total calorie intake.

However, the science is not yet conclusive on this topic. Whether or not increased calories directly cause acne, and whether reduced calories could help clear up acne is still up for debate and will require further research.

Let's have a look at how calories affect hormones in the body, specifically insulin, and how this might be associated with acne.

Warning: Deep science ahead! (but it's kinda interesting actually). 

Insulin May Be Associated with Development of Acne

Acne and Insulin Hormones

Researchers have associated three insulin hormones with acne development. These hormones include insulin, insulin growth factor 1 (IGF1), and IGF1 binding factor (IGFBP-1). Researchers have identified that the connection between insulin hormones and acne is due to the action of two proteins called FoxO1 and mTORC1. FoxO1 acts to suppress skin oil production and mTORC1 acts to promote skin oil production. Researchers have found insulin acts by decreasing the amount of FoxO1 and increasing the amount of mTORC1 in the body. When FoxO1 levels are decreased and mTORC1 levels are increased, this leads to a large increase in skin oil production that likely plays a role in acne development.1-3  

British Journal of Dermatology

In support of these findings, a 2016 study compared the IGF-1, FoxO1, and mTORC1 levels in acne and healthy patients. The researchers found that acne patients had higher IGF-1 and mTORC1 levels compared to healthy patients.4

Caloric Intake and Insulin Hormones

As scientists believe that insulin level changes may lead to acne development, researchers have begun investigating whether a person’s caloric intake affects the level of insulin, insulin growth factor 1 (IGF-1), and IGF1 binding factor (IGFBP-1). 

Two studies have been performed in order to better understand the connection between high caloric diets and insulin hormone levels. After completing the studies the scientists ultimately concluded that patients consuming the low-calorie diets had decreased blood insulin levels and an increase IGFBP-1 levels, which acts by binding to IGF-1 in the blood.  With these findings, scientists believe that consuming a high-calorie diet will lead to greater insulin and IGF-1 levels, which then causes a decrease in FoxO1 and an increase in mTORC1. Decreased FoxO1 and increased mTORC1 would lead to more skin oil production that could potentially lead to acne development.2

Hypothesis Connecting High Caloric Diets and Acne

Extreme Low-calorie Diets Result in Less Sebum Production

Going extremely low on calories is, of course, not a sustainable way to live. However, two studies done in 1970 and 1972 showed that severe caloric restriction decreased skin oil secretion dramatically.5,6 This is interesting from a scientific standpoint since increased skin oil production is directly related to acne. If fasting creates significantly less skin oil, would excess calorie consumption create significantly more skin oil? This remains to be seen.

Expand to read details of studies 

Journal of Investigative Dermatology

The first study, performed in 1970, looked at the response of the sebaceous (skin oil-producing) glands to caloric restriction in 18 overweight patients for 4 to 8 weeks. They found an average decrease of sebum production of 40%.5

The American Journal of Clinical Nutrition

The second study, performed in 1972, followed 4 patients who fasted for 10 days. After 5 days of fasting, all fats in the skin oil on the forehead were reduced, except for a type of fat called squalene. When normal diet was resumed, the change reversed.6

The Bottom Line

When it comes to diet and acne, one of the most overlooked variables is calorie consumption. Lower calories may temporarily decrease acne and higher calories may temporarily increase acne. Therefore, when people remove "bad" foods from their diet in an attempt to help with their acne, they might see a temporary reduction in acne and believe it is due to eliminating those "bad" foods, when in fact, it is simply that by eliminating those foods the person reduced his calorie intake. 

While a potential link exists between caloric intake, insulin levels, and skin oil production, more research is needed to determine if low-calorie diets would actually clear acne. In the meantime, rather than eating an extreme diet of very low calories, eating sensible portions of nutritious, low glycemic foods will contribute towards keeping both your body and skin healthy and in good condition. 

Eat Sensible Portions of Nutritious, Low-Glycemic Foods

The Experts at Acne.org

Our team of medical doctors, biology & chemistry PhDs, and acne experts work hand-in-hand with Dan (Acne.org founder) to provide the most complete information on all things acne. If you find any errors in this article, kindly use this Feedback Form and let us know.


  1. Pasiakos SM, Caruso, C. M., Kellogg, M. D., Kramer, F. M. & Lieberman, H. R. Appetite and endocrine regulators of energy balance after 2 days of energy restriction: insulin, leptine, ghrelin, and DHEA-S. Obesity 19, 1124-1130 (2011).
  2. Henning, P. C. et al. “Effects of acute caloric restriction compared to caloric balance on the temporal response of the IGF-1 system.” Metabolism 62, 179-187 (2013).
  3. Melnik, B. C. Western diet-induced imbalances of FoxO1 and mTORC1 signaling promote the sebofollicular inflammasomopathy acne vulgaris. Exp. Dermatol. 25, 103-104 (2016).
  4. Agamia NF, Abdallah, D. M., Sorour, O., Mourad, B. & Younan, D. N. Skin expression of mammalian target of rapamycin and forkhead box transcription factor O1, and serum insulin-like growth factor-1 in patients with acne vulgaris and their relationship with diet. Br. J. Dermatol. 174, 1299-1307 (2016).
  5. Pochi, P. E., Downing, D. T. & Strauss, J. S. Sebaceous gland response in man to prolonged total caloric deprivation. J. Invest. Dermatol. 55, 303-309 (1970).
  6. Downing, D. T., Strauss, J. S. & Pochi, P. E. Changes in skin surface lipid composition induced by severe caloric restriction in man. Am. J. Clin. Nutr. 25, 365-367 (1972).

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