Topical Retinoid
Reviews
3.4
1969 Reviews
Topical Retinoid
Efficacy
50%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid
Side Effects
Low
Topical Retinoid
Acne.org’s Real World Take
Works about the same as the other two topical retinoids, tazarotene and adapalene, and lands in the middle of those two when it comes to side effects. Should provide partial clearing, but comes with sensitivity when you first start using it. It probably won’t be a total game changer but it should help reduce acne.
Topical Retinoid
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Tretinoin
Compare To Other Treatments
5
22.1%
4
32%
3
21.6%
2
14.9%
1
9.4%

Used Tretinoin? Rate It:

Choose from 1 to 5 stars
May 11, 2018
Went from mild to severe
I wish I did my research before putting it on my face! My derm prescribed me this and didn't really tell me much about it other than to use sunscreen. I have never had acne this bad before, I'm eating all the right things... I cut out everything like (dairy, meat, gluten, anything you can think of that causes acne) all I eat is vegetables and fruits with salads and salmon w beans. Still wonder why I get really bad cysts, and pimples in places I never had before such as my neck and forehead. My skin is so sensitive to the sun now! And it's super red. With summer around the corner I decided to stop using it. Hope this diet calms my active acne. Good luck to those who are using this. Not for me.
September 16, 2017
Mild acne and sensitive skin
I used Retin A 0.05% cream for two weeks and got clear skin after one week. I didn't have harmful effects, except that my face got darker and red, even though I took every precaution (sunscreen/hat). I live in a very sunny place, so definitely not worth it. Advice: I've been using Glycolic Acid 10% Lotion. Its not abrasive, I dont wear sunscreen and my skin is amazing.
December 5, 2017
U got darker as u got inflammed because of it's strength or u might applied more than what it was recommend (pea size for the whole face!) .. the darkness is a sign of a healing process after the inflammation .. try using it once a week and see how it goes at first, if u can handle it move to twice a week max as u r having sensetive skin type.. when u use it once a week at the beginning don't apply it for the second time unless u have stopped peeling from the previous application and you are not having any sign of irritation.. i learned doing this in a hard way
December 5, 2017
And yeah while using it don't use any other harsh product.. even the soap or the cleanser, use a gentle one
April 2, 2017
Side Effects massive and no clearing
Hi everyone! I am writing on behalf of my 16 year old daughter who would never in a million years write a review herself! But I have to say that this product has been the bane of my existence for the last year+. But I have a very head strong daughter who somehow has it in her head that she should keep using it. The background is that like most teens, around 13, my beautiful fair skinned (blue eyes, blond hair) daughter started breaking out. We immediately started trying everything, first Proactive for a while but there was literally no change at all with that stuff. After about 2 months on Proactive, she stopped altogether and just started using bar soap. One day she asked me to go to the dermatologist - I think she had been talking to someone at school about it. So we went and they prescribed Retin A. I was 100% against a prescription of any type but I was better with a topical prescription than an oral antibiotic. she started with Tretinoin 0.025%. Again, there was no visible change in her acne but there was a visible change in her face. Her pores all over her face got much larger, so that I could see them from 5+ feet away and I started noticing scarring which, as a mom, I absolutely hate to see. Around that same time, my younger daughter, who was now 13, began to get acne as well but had heard of another product at her school called Ninja Skincare. As kids do, she wanted to do what her friends were doing so we bought it. It was very affordable and had incredible customer service so I was pretty impressed. Her acne went away in a heartbeat. Literally within a month it was entirely gone. Obviously, I was pressing my older daughter to try it too but she wasn't having it. She blindly believed that the doctors should know the best and wanted to go the route of the dermatologist. Sorry - long story short, we continued with Retin-A because that is what the dr told her to do. But the doctor didn't tell us about the side effects even after we asked about the pores and the scarring. I should have done more of my homework. The breaking point was when we went on a family trip to Mexico over Thanksgiving and even with sunscreen, her face turned BEET red to the point where strangers on the beach came up to me and pointed it out and suggested I get her out of the sun. I had no idea what was happening. We went home and iced her face, put aloe vera on it and her face remained burnt for over a week, sensitive to the touch. I felt so bad for her. Needless to say, the beach trip was completely ruined for her which sucked but at least she finally agreed that Retin-A was a bad choice for her. Now after about 4 months on Ninja, she is entirely clear and her scars from that period are starting to face with the help of Salicylic acid every day. I have read all of the reviews here and am happy that some people got relief from this product but I honestly don't understand why it worked for some people without these horrific side effects while for others it doesn't? I guess everyone has their own sky types. I am just glad we are finished with the prescriptions and dermatologists!
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April 19, 2017
Hi has your daughter experienced any improvement or found remedies for your skin texture and pores? I endured the same exact unfortunate experience with retin-a. It's tough to watch skin transform for the worse when we were only trying to be pro-active and make positive changes.
November 8, 2017
Just a note for the future, ice will make sunburn much, much worse. Tretinoin has side effects, but is actually helpful in fading scarring.
November 23, 2017
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March 31, 2017
Don't use it if your acne is mild!
My dermatologist put me on Retin A for keritosis pilaris on my face and it wasn't too bad before. I had around 3 - 5 little bumps on my face that came and sometimes I even had none. Well I wanted to fix the bumps anyways so my dermatologist put me on Retin A. This broke me out so bad, but I kept using it because I was told it would get worse before it got better. Well, then my skin started peeling and it was red and inflamed and painful. And now my face is covered in the little bumps and cystic acne - and I NEVER had acne before using this medication! It looks terrifying - my face has never been this bad before! There's little to no smooth surface on my face, it's just tiny little bumps and giant red cystic pimples all over my face. I've been using it for almost 4 months now and I don't see it getting any better from here. I would rather deal with what I had before.
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October 13, 2016
Hair loss after 2 months use
After a little over 2 months of use, retin a started causing my hair to shed abnormally. I have used retin a in the past, but never seriously, I'd use it here and there when I remembered but I was breaking out especially bad (I realized it was due to MAC waterproof foundation) so I was going back and forth between .5 and .25 every night. After a month or so my hair started shedding more than usual, and I tried contributing it to anything I could bc I had no idea retin a could cause hair loss. When I got close to 2 months of use I started reading around and realized hair loss was indeed a side effect of retin a, maybe rare but it exists. Retin a is essentially just Accutane you are applying to your skin, which afterall is your largest organ and main way you detox. Slathering it with Accutane would seem to lead to side of effects of regular Accutane. Since stopping I believe the shedding is slowing, but I am taking all sorts of supplements meant for hair and got special shampoos. If you start shedding while using this, don't dismiss that retin a may be the culprit. I have been using the Skin Cueticals acne kit with great results thus far (only a week). I have a derm apt soon and I might ask for Azeliac acid.
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July 9, 2016
Not a miracle, but still hopeful
Please see the update that I posted under comments. This stuff has destroyed my skin. I am not sure if it will ever recover. Please note that I didn't have red, peeling, or irritated skin while using it every other day. I followed all of my derms instructions and followed up with them monthly. I can't believe that I am writing this, I really thought this would work for me. I am 36 years old, female and have sensitive, acne-prone, oily skin. I have been using Tretinoin 0.025% Gel for 6 months for moderate inflammatory acne caused by taking oral steroids for a medical condition. OK, so, the Initial Breakout was brutal and lasted much longer than I expected, started at about week 3 and lasted for months! My skin is not yet better than it was before treatment (getting there though, hopefully, I don't know, it seems like acne comes in waves, right?). My pores appear larger than before and I am getting indented scars frequently, my skin has always been acne-prone and I have never scarred before. My Dermatologist says that this does not promote scarring, but I am not so sure. These scars may have happened anyway, I don't know, my acne has never been this bad before. I tried to use this every day, but ended up with an irritated-orange-peely texture, this is much better after switching to every other day, though the texture still is not normal. It definitely peels a thin layer of skin off and reveals newer skin with every use, a very good thing. It also brings closed comedones to the surface quickly. This is definitely not a miracle cure, but it just doesn't seem like there is one when it comes to acne... I do see glimmers of hope with this, but I think that it takes a very long time and must be used in combination with other treatments, especially for people that have something internally driving their acne.
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September 25, 2016
Hi, how is your skin now. I'm just going through just the exact thing and i tend to think it's not working and wondering about quitting it. Please let me know how is your skin now
October 8, 2016
Hi Archana_ess. I just wanted to add an update. Retin A has destroyed the texture of my skin, enlarged looking pores, orange peel texture, reactive skin. This is just plain ugly. I don't know if it will ever improve. This is not listed as a side effect but others have had this same experience. My skin was never cleared of acne on Retin A, it only got worse and worse. It also made my skin scar much more easily. I discontinued it 9 weeks ago. I will say that Spironolactone has cleared the acne by about 90%. I used to get it all over my face, now it is mostly on my chin, is much smaller and is much easier to deal with. This texture though, I don't know what to do and I am much more depressed about this than I was with the acne. It just doesn't seem possible that this could ever go away. I know lots of people have great success with Retin A, but I cannot recommend it. I wish that it had never touched my face. I hope everyone else has better luck than I did.
April 19, 2017
Hi Sararey, have you experiencedone any improvement or found remedies for your skin texture and pores? I endured the same exact unfortunate experience with retin-a. It's tough to watch our skin transform for the worse when we were only trying to be pro-active and make positive changes.
January 20, 2016
Does not work for everyone. I gave it 8 months, after Doctor follow up.
I will keep this brief. This did not work for me, and I gave it 8 months. I keep my washing regimen simple and I barely use makeup. I am 32 and have had moderately bad acne since I was a teen. Skipping forward, what ended up working beautifully for me was hormonal regulation by birth control and low dose spirolactone to block androgens. Perfect. I was on that from age 29-31 and it cured all my acne. Before that, I tried all sorts of topical and oral antibiotics with no success. I read and tried Retin-A. Gave it 4 months, then another 4 months after talking to a doc. My acne got worse, and worse, and worse. One guy mentioned chemical burns on this board. That was actually what I got!!!! At one point, my chin started pussing and scarring. That was at 7 months. I lessened my usage (every other day) and it never got better. Until I completely stopped. My face went back to baseline and I thought that looked wonderful compared to the horrible acne I had suffered while being "patient" on this. Point is, regardless of wonderful reviews from a majority, it does not work for everyone, even with a clean regimen and patience. Another point is, something else worked. I've stopped birth control / spirolactone because of future family planning. My acne is not ideal but manageable with $10 benzoic peroxide. That good old teenager stuff that works ehhh, but I guess I no longer care as much as I once did. Maybe not caring helped my face.
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January 3, 2016
Did not work for 14 year old female
We have tried Tretinoin, Doxycyline, Onexton, and Epi-Duo. None have made a significant difference, thus the dermatologist prescribing all these products. During these trials, we cut out dairy and reduced sugar. Still no difference. Was told to use Cetaphyl and also CeraVe. I believe, if you have hormonal acne which my kid has... no external product is going to cure acne. It really didn't reduce it that much either.
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September 27, 2015
Help!
Wow, what a disaster. I went to the Derm because of my excessively oily skin and the occasional breakout. Nothing that I would have gone through this for. Within the first week of use my skin broke out on every square inch of where I applied this product. My skin which was once smooth with very few problems (sometimes not even a pimple), now covered, I mean COVERED, in bumps. Literally looks like gravel on my skin. I've read several posts and reviews, trying to stay positive and continue use, thinking this was just my skins initial reaction and that my skin is just "purging". It has been a month and literally looking in the mirror makes me want to cry. My skin is red, inflamed, painful, tight and covered in bumps and whiteheads. I wish I'd never started using this medication. I am not even sure if it will actually eventually clear my skin. Total hell. I feel like it is a waste if I discontinue use as I have come this far but please be aware: if you are using this to tame a few minor breakouts and don't want to possibly be TOTALLY broken out for over a month, I'd steer clear.
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July 23, 2016
This is the beautiful "purge" period. It sucks horrendously and completely ruins your self esteem. I know it all to well. You can survive this period by a) using coconut oil as a moisturizer and b) using tea tree oil as a toner. both of these things have antibacterial properties and help counteract the "purge" period. Also, vitamin E oil is great for the super dry patches.
April 7, 2015
not for sensitive and dry skin
im 16 i've been on this treatment for 2 year but I stopped using this after two day because I got a rash on my face it was red and it hurt really bad. DON'T GET RETIN-A!!!!!!
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May 27, 2015
You've been on this treatment for two years, but stopped using it after two days? Your math does not compute. And yea it does hurt, like a MOFOBITCH. But then you look really awesome. I mean if you stick it out. Don't ruin this for other people because you candle handle it.
October 18, 2016
the other person who commented doesn't get it..this stuff destroys people's faces..maybe not everyone..maybe not even most people...but for some It does..by leaving a negative review, it is not "ruining it for other people because you can't handle it" , it is saving other people from making the same mistake. That comment is utterly ridiculous, besides the fact that that, yea, it doesn't make a whole lot of sense that you got a rash after two years..but I still agree that retin a can be a nightmare for certain people

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.