Topical Retinoid
Reviews
3.4
1972 Reviews
Topical Retinoid
Efficacy
50%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Topical Retinoid
Side Effects
Low
Topical Retinoid
Acne.org’s Real World Take
Works about the same as the other two topical retinoids, tazarotene and adapalene, and lands in the middle of those two when it comes to side effects. Should provide partial clearing, but comes with sensitivity when you first start using it. It probably won’t be a total game changer but it should help reduce acne.
Topical Retinoid
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Tretinoin
Compare To Other Treatments
5
22.1%
4
32%
3
21.6%
2
14.9%
1
9.4%

Used Tretinoin? Rate It:

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April 4, 2011

Pros:

shrinks zits
lightens scars
soft skin

Cons:

dry skin
kinda itches
hard to tell if inital breakout?

My doctor suggested this to me for me to unclog my pores and lighten post acne hyperpigmentation. At first I was hesitant to use this because of the intial breakout I read about, I was already breaking out 1000x's worse than usual and couldn't deal with more acne. However, much to my suprise I didn't notice much of an I.B. at all. Yes, I still got new pimples, but nothing crazy like I thought. It made my current zits less red, imflammed, and smaller. I was so excited! Make sure you wait 20 minutes after washing your face to apply this. It is a little drying but not too bad. I notice it after a while, but doesn't 'flake off'. My scars are lightening, finally! And overall my skin looks healthier. I've only been using this for about two weeks, so I'm excited for the future!
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October 18, 2010

Pros:

- no more DEEP PIMPLES that Benzoyl Peroxide does nothing to (in my case)
- It is very effective and does work eventually
- Smooths out and brightens my skin with regular use
- Apparently slows the development of wrinkles as a bonus

Cons:

- It makes your skin worse before it makes it better, use it for 2-3 months before giving up on it
- It causes mild skin flaking (I use it over night and exfoliate gently in the morning), if you're getting too much of this reduce usage
- It can take a while to build up a "tolerance" to the effective strength (may need to build up to the proper strength, skin may be red and irritating until it gets used to it)

This in combination with Clindoxyl (antibiotic infused Benzoyl Peroxide - great for the "surface" pimples), and a red/blue light therapy lamp, has fully cured my once severe acne. Retin-A is necessary because it is the only part of my routine which addresses the painful deep pimples I get. Now people compliment me on my skin! Try it! I use the high concentration 0.1% cream (as opposed to the 0.05%) and dilute it with some vitamin-k cream to reduce irritation.
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July 16, 2010

Pros:

I just started using it but I can feel it drying out my acne!

Cons:

Don't have any complaints yet

The bottom line is that I really have high hopes for this and hope that this is the answer to my prayers, because its been hard lately to have so much acne!
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April 12, 2010

Pros:

Smooths skin texture, reduces blotchiness, prevents pimples, helps pimples heal faster

Cons:

Takes a full 3 months to have effectivenss and causes initially breakout for the first 3 months (the most acne I have ever had at one time), dry and flaky skin but adjustment occurs through time (I used Retin A micro to decrease this), thinner skin which requires sunblock

Did not totally cure my presistant adult acne, but much reduced it, enough so that it doesn't bother me when I wear a little makeup. The acne is smaller and easier to address. My skin is glowing and smooth. It is the best exfoliator out there plus it has anti-aging benefits. It is the backbone of any mulitple regimen acne plan because it helps other products penetrate the skin better.
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February 21, 2010

Pros:

-Cleared up small pimples around nose area
-Face looks less red the morning after

Cons:

-Has done nothing for blackheads around nose
-Make breakout on forehead bigger and worse
-Bigger and more red pimples are emerging

I started using the 0.05% early in December. I used it for around two months and it didn't help me very much. It cleared the pimples in my nostril creases, but essentially made my forehead break out much more. I went back to the doctor, and she gave me a higher dosage, 0.1%. I have been using that for around a week or so, and I haven't noticed a difference. I use it at night, and the morning after my skin does look less red. I do experience some minor peeling around my nose, on my chin, and a bit on my forehead. To combat this I use Aveno Clear Complexion Moisterizer, more than I did before I started this treatment. Even though my first two months of the lowest dosage didn't do anything, I am hoping that if I stick with this dosage my skin will clear up.
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February 13, 2009

Pros:

Shrinks Pores, No more pimples after time, great product, no cysts

Cons:

Initial Breakout, Dryness

Im SICK of people giving retin a one star because they dont know how to use it. Use a pea sized amount every night after cleanser your face with a gentle cleanser. IT TAKES TIME YOU SKIN WILL GET WORSE FIRST. It is worth it, stop being impatient people, just stick with it.
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August 20, 2016
Works in due time.
I've had acne for about ten years, and it was bad during high school but has cooled off a lot. I still wanted to see what could be done about the oily skin and few whiteheads that would pop up around the mouth and nose area, so I went to a dermatologist who gave me this and doxycycline. She started me off on the 0.025% which made be break out a little but worked well. It smoothed out any scars and pretty much solved the oil problem. After a few months she put me on 0.05%. This made me break out more and chapped my nose area. It went away after about week 4 and I'm now in week six and things are much better. Not many whiteheads or any of the pigmentation, and it's working better for the oil. If you're struggling through the so called "purge" just know that I did as well, but it will get better. It did for me, and I'm an oily Italian to begin with! Good luck!
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March 29, 2016
it works, but will take a while
The first time I used Retin-A was over a year ago, and I remember using it for about 2 weeks and wondering why nothing was improving. However, my doctor told me to give it another shot, but to wait it out this time. I had moderate acne, mainly just the small red pumps down my T-Zone but especially on my forehead. I started Retin-A around mid October (2015) and began peeling terribly and getting really bad acne (a sign that it is working; it has to get worse first) that peaked around early December. It was really a terrible time for me--I tried so hard to hide my acne and and didn't want to go outside or face people directly because it got so bad. But I stuck with Retin-A and by January, most of the pimples had disappeared, and I just had some darker marks left over from the acne. Now, it's almost April, and the scars have been gradually fading away. TL;DR: Retin-A really works, but you have to be consistent with it even when the acne is getting worse.
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March 5, 2016
Patience is a virtue
I've had mild to moderate acne since I was 14. I'm now 26 and still suffering. I've tried everything under the sun!! I'm on week 8 of Tretinoin .5 cream and let me tell you that you definitely need patience when it comes to this medication. I am red, broken out and dry. I've been using FAB Ultra Repair Cream for dryness and it's pretty helpful. Otherwise I've been super depressed because as we all know living with acne is embarrassing and terrible. Reading your positive reviews is extremely helpful and I'm trying to be patient. Hopefully I'll get some good results soon because I haven't been wanting to leave my house or look at anyone for the past month and a half. I'm just looking forward to the day when I can feel good about myself again.
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April 2, 2016
Just keeping you all updated I'm almost on week 12 of tretinoin and I don't have any active cysts just a few old scars. IT'S AWESOME. I also started spironolactone (100 mg) about 4 weeks ago, so I definitely think that helped and I've noticed my oiliness improving slightly. I honestly started tretinoin to get rid of my cray cray blackheads but haven't noticed much improvement in that department 🙃 So hopefully soon? I have also noticed that a baby laugh line I had is very hard to see now so that's cool. I'll keep updating.
May 8, 2016
I know it's difficult. I wish I found this product when I was only 26. I've had acne my entire life and it took until I was in my 40s for get prescribed Retina. I'm 50 now and still use it every night! I might get one pimple sporadically! I can deal with one zit a month! Hang in there and be patient like everyone says. You will be sooo happy with the results. One another positive note, You skin will stay looking much younger. As I said I'm 50 and do NOT have one, single wrinkle yet. Everyone thinks I'm in my late 40s. Retina is a life saver. Good luck to you hun!!
May 10, 2016
thank you for your encouraging words!!
May 10, 2016
i am almost on month 17 and still not getting the results i want. ive added spiro and birth control for hormonal acne so hopefully that helps!
December 31, 2015
A lot of patience and dedication is needed
I am currently in my mid twenties and have been struggling with moderate acne on and off since puberty (mostly around my mouth and sometimes between my eyebrows, always deep and painful and always leaving red scars that fade after a few months). I have never had amazingly clear skin, but have had times when I was okay with my skin. Unfortunately the past few years have not been showing any signs of getting better, despite my age. I was hoping it would clear up as I got older. I was finally fed up with it and was prescribed retin a micro 0.1% after a recent chain of breakouts. I have been following the instructions of the doctor, pharmacist, and the insert with the bottle. Once a day, at night, 20-30 minutes after I wash my face I use a cotton pad to apply the cream to my entire face. I have the pump form of the cream and I use two pumps per application as directed. FIRST 3 WEEKS: The first three weeks of using this cream have been a struggle, to say the least. I have not noticed much improvement yet. I am most definitely experiencing the purging breakouts that many other people have experienced. As soon as I started using the cream, and until the end of week 3, I have had non stop painful breakouts. This cream is not fun. It is potent and it works quickly. For the past 3 weeks I have had at least 2-3 painful pimples somewhere on my face at any given time. The kind that you are reminded of every time you smile or talk (gah!). Fortunately, I am not experiencing any of the severe dryness, redress, or overall peeling that others have. In fact, my face is much much oilier than usual. I have slightly oily skin normally. Since I've been using this cream, I wake up to my face feeling like butter. I wash with dove sensitive skin soap in the morning and at night, and sometimes I shower (after gym) and rinse my face half way through the day. Most days my skin (face only) is so oily that I need to use an oil absorbing pad early afternoon to make myself feel clean. What I have noticed is that this cream makes my pimples come and go in about half the time they normally would. For example, I have woken up in the morning and felt no pain and no lumps building under the skin. By 5pm a big deep pimple will have appeared and not only be visible but be painful. I have gone to bed with no pain and woken up in the middle of the night with a massive throbbing lump on my chin preventing me from falling back asleep. With the bad, there is also a good. Pimples tend to clear up faster. They peak in about 12-24 hours on average, and settle down and dry up in about that amount of time as well. So a pimple can come and go in about 1-2 days, which is less than half the time than normal for me. You know when you have some dead skin from a dyeing pimple on your face and you just want to pick it off so your makeup doesn't clump around it? Well this cream makes your skin thin enough (or irritated enough or whatever it is) that it will usually bleed if you pick. And I'm not talking about picking something that isn't ready and needing to use force, I'm talking about dead skin just sitting on top of your face. So you are suck between leaving a chunk of dead skin on your face or picking at it and having the spot bleed. Both look equally as bad when trying to cover up with makeup. And even if you do manage to successfully pick it off without leaving a scab, a new layer of dead skin somehow manages to appear insanely fast.. like before your next bathroom break/face check fast. I have become accustomed to checking my face every hour in an effort to keep it looking alright. It seems that every time I look in the mirror something has changed. That being said, I am only experiencing dryness on the pimples themselves, the rest of my clear skin (cheeks, jaw, nose, and most of forehead) feels great. It actually feels much nicer than before, very soft and smooth. WEEK 4 I am now onto my fourth week and I am trying my best to stay positive and motivated to continue. I know that it can take 8-12 weeks to see results. These past 3 weeks have felt more like 3 months. The breakouts are happening so fast that the previous areas do not have time to heal, leaving my face a nice combination of red irritated lumps and red scars that haven't had time to heal yet. My face looks like an absolute mess without makeup, and it is the first time in a long long time (and there hasn't been many of these times) that I am even embarrassed to face my family without makeup. Above all else, its been tolling on my emotions. It hasn't been fun to constantly feel self conscious about my face, but to also have to feel the pressure of pimples at all times. WEEK 5 & 6 In week five and six I have experienced what I thought was the beginning of better skin... twice. Both times bounced back with painful breakouts. I started using Thyers Rose Petal Witch Hazel (alcohol free and organic) toner at morning and night to try to reduce inflammation. I am noticing that the pimples aren't coming and going as fast. I am also noticing that my forehead, and upper lip/nose area is breakout free, but my chin is still a raging mess. At the moment, my chin is worse than it has ever been. Everywhere else on my face, except my chin, I am only getting tiny little white heads that aren't painful or deep. Still experiencing lots of oiliness. What I have learned so far? I wouldn't take this cream lightly. If you are going to begin using it, make sure you are willing to commit to the full 12 weeks, otherwise you are probably going to go through purging and not see the potential result. If you think your skin can't get any worse, this cream will probably surprise you. If I quit now, I feel that I will never truly know if this cream works or not, so I am keeping my fingers crossed that I will see improvement within the next month or two because it truly is miserable. I will continue to update as the weeks go on. Good luck to everyone trying this cream, hang in there!!
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May 19, 2016
Please keep us updated ma'am!
July 13, 2016
Sorry for the very delayed update! Unfortunately, this cream didn't work for me. I used the .1% religiously, every night, for about 3 months and noticed very little difference in breakouts but very dry skin around my chin, mouth, and nose area. The area under my nose got to a point where it was so red and inflamed from being dry that my Mom actually asked if I was okay. It scarred. I was constantly getting sun burns which stung for 2 or 3 days and lead to a lot of surface level peeling. I had to stop using the cream for a week or two to give my skin a break, and my skin broke out heavily after 2 weeks of not using it. I mean, deep, marble sized, painful, hideous. At this point being at least 12 weeks into using this cream, I asked my Doctor to prescribe a lower dosage as my skin under my nose was literally being destroyed. He prescribed me .05% of retin a (not micro). This cream actually seemed to be a better balance for me. Dryness wasn't a problem, it felt nice, my skin was nice and smooth. However, I was still breaking out and it wasn't showing a world of improvement. My acne also started to venture out to my cheeks and jawline which I have never had a problem with before. I implemented a benzoyl peroxide treatment in the morning (with the retin a at night), I was able to keep the dryness at minimum, but breakouts didn't stop. I used this lower dose retin a for another 3 months. At this point I saw another dermatologist who highly recommended accutane. I try to avoid drugs as much and often as possible. I was very reluctant. I decided to go on birth control (diane 35). I was on it for 2 weeks and felt horrible. Crying spells, sadness, tender body parts, anxiety. Im not saying it wouldnt have gone away with consistent use, but I figured if I were going to go through these side effects I might as well be on accutane. I have now been on accutane for just over 2 weeks (40 mg), and I can tell you that the side effects, for me, are 100x milder than what I felt on diane. I pretty much feel back to myself. I stopped using all acne related creams and topical once I started accutane. I am still experiencing purging. Lips are getting dry but no dryness of the skin yet. Good luck everyone!

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.