What Is It?
Topical silicone treatment involves the application of a silicone-containing gel or gel sheeting on the hypertrophic (raised) scar for at least 12 hours a day, usually for about 2 months. Silicone sheets can be cut to fit the size of the scar. It is suggested that the effect results from hydration of the skin via silicone. Another proposed mechanism of action includes silicone leading to a reduction or transformation of growth factors present in the scar.
Scar Height Reduction
Strength of Evidence
Average 53% reduction in scarring
Success Rate
Strength of Evidence
Average 25% reduction in scarring
Mean improvement in VSS total score
Strength of Evidence
Average 52% reduction in scarring
Mean improvement in VSS pigmentation score
Strength of Evidence
Average 52% reduction in scarring
Mean improvement in VSS height score
Strength of Evidence
Average 88% reduction in scarring
Mean improvement in VSS pliability score
Strength of Evidence
Average 39% reduction in scarring
Mean improvement in VSS vascularity score
Strength of Evidence
Average 45% reduction in scarring
Side Effects
Low-Medium
Low-medium side effects and adverse reactions