What Is It?
Topical silicone treatment involves the application of a silicone-containing gel or gel sheeting on the raised scar for at least 12 hours a day, usually for about 2 months.
It is suggested that the effect results from hydration of the skin via silicone. Another proposed mechanism of action includes silicone leading to a reduction or transformation of growth factors present in the scar.
Good or Excellent Response
Strength of Evidence
25% of patients achieved a good (>50%) or excellent (>75%) improvement in scarring
Scar Height Reduction
Strength of Evidence
Average 53% reduction in scarring
Mean improvement in VSS total score
Strength of Evidence
Average 52% reduction in scarring
Mean improvement in VSS pigmentation score
Strength of Evidence
Average 52% reduction in scarring
Mean improvement in VSS height score
Strength of Evidence
Average 88% reduction in scarring
Mean improvement in VSS pliability score
Strength of Evidence
Average 39% reduction in scarring
Mean improvement in VSS vascularity score
Strength of Evidence
Average 45% reduction in scarring
Side Effects
Low-Medium
Low-medium side effects and adverse reactions