Antiandrogen
Reviews
4.1
1330 Reviews
Antiandrogen
Efficacy
68%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Antiandrogen
Side Effects
High
Antiandrogen
Acne.org’s Real World Take
“Spiro” has been shown to work in a real and noticeable way most of the time. However, messing with hormones is messing with hormones and it’s best to proceed with caution.
Antiandrogen
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Spironolactone
Compare To Other Treatments
5
51%
4
28%
3
10.1%
2
4.9%
1
6.1%

Used Spironolactone? Rate It:

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November 2, 2014
works only if you have pcos, hormonal acne. no permanent fix
I was diagnosed pcos 2 years ago and they put me on this drug. Worst mistake of my life. I've recently discovered( change doctor)I don't have any pcos( weight 110 lbs, height 175cm, no hirsutism, perfect blood exams,no insulin issues, perfect testosterone and dhea levels even before this cure, no issues with menstrual cycle)and the previous doctor was totally wrong and gave a wrong diagnose. My acne was never completely cured while on this drug despite being on 100 mg per day and despite my acne was mild, never more than 5 pimples/ papules per time. Beware of the side effects which aren't mentioned like drying of the skin and scarring. My skin became superdry in the last few months but my acne is still there. I'm weaning off of it but it's still dry. Scarring, which I never experienced before, is caused by dry skin and the fact that skin wounds take more time to heal if the skin is dry. Acne is not only caused by oily skin but it has to do with the oil and the pores of your skin. That's why you don't cure acne just by suppressing oil, because even the smallest part of oil can get stuck in your pores if they don't work properly. Moreover this drug is not a cure for your acne, because even if it works when you stop it your acne will come back. You'd better give accutane or exfoliators a try, this is just a waste of time and no permanent Fix. My skin has scars now Thanks to a wrong diagnose, a wrong cure and a stupid doctor who told me to stick with it for almost 2 years. I'm considering a lawyer and will start accutane in a few weeks. Even my periods went totally crazy,came every two weeks, and I needed a progestinic 4 days a month to fix it. Stay away unless you have real pcos or you are looking for troubles.
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September 23, 2015
I would never in my life so accutane. That drug messed up everything. I lost my hair and it messed up my digestive system . I have not been able to have proper bowel movement since that poisonous drug. I don't know why that have that crap on the market . Also after getting off k broke out terribly again
June 11, 2014
Spiro=Patience!
Ok so I have had acne since I was a teenager. I'm 23 now so it's been a long time. I went on birth control during high school which managed the problem for a while. When I was in college I went off birth control for about a year, and then started getting horrible cystic acne. They were large, painful cysts which usually came 3 at a time. For a while birth control and antibiotics did the trick. After switching birth control and going off antibiotics, the cystic acne came back. Going back on antibiotics didn't work this time, so I asked my dermatologist about Spiro. Accutane has always been my last possible result so I wanted to try this first. This site was what motivated me to try Spiro and I will say that it has definitely worked for me! Like everyone has said, this med takes time to settle in so don't be discouraged if it hasn't been a miracle after 2 weeks. I'm on my 3rd/4th month and I've started to see big big results. I changed my dosage about 3 weeks ago which has helped too (I'm on 75mg vs 50) so that may be what some people need to do. My breakouts haven't disappeared (I'm superstitious so I feel if I rave about this I'll get some horrific breakout) but they are minor if they happen and are basically pimples rather than giant cysts. Originally I was wary about trying this because of side effects but here's the deal---side effects may happen, they may not and they are different for everyone. If it doesn't work for you, stop taking it. My side effects were muscle aches and lack of appetite during the first few weeks. The muscle aches went away (keep exercising, this really helps) and I really have no complaints about the appetite part, I lost some weight which is always a perk. Some people on here have said they had hair loss, weird menstrual cycles, weight gain. Again, this is possible, but if you are really looking for a solution, Spiro is worth a try.
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August 14, 2013
Spiro 100 mg then 200 mg

Pros:

Reduced cystic acne
Hair did not get oily for days

Cons:

Hair Loss (head)
Initial Breakout/takes time to take effect
Irregular periods at first

Hello, I began using spiro 100 mg in January after BC was not being as effective controlling my cystic acne as it used to be. I had already read about spiro and was interested in the drug before I went to see my doctor and was happy to hear that is what she recommended. My regimen now included Beyaz BC, Spiro 100 mg daily, Cetaphil wash and moisturizer (twice a day), and Aczone Gel (twice a day). After about 5 days of taking Spiro i broke out with a couple of cystic horrors which took forever to heal but after that I did not get any new ones for that first month. I also had an irregular period that lasted for about two weeks, went away, then came back for a week. The doctor said that it could happen and it would be regulated after the first month, especially since I was on BC. After visiting my doctor, who was not happy with my results because I was getting tiny white heads here and there that I wasn't getting before, I was upped to 200 mg a day. At 200 mg, I broke out with 3 huge cystics around my chin area (which is where I always get them) at first. I did not get any big breakouts for two months after that and the small white heads disappeared, however, after a month, I broke out again with two big cystics so my doctor and I decided that I would go on Accutane for 6 months since this wasn't the solution I was looking for. Some other side effects that I experienced are heavy hair loss. My hair thinned so much while I was taking Spiro. I also notice that my breasts were really tender at first and got fuller as I continued to take the medication. I also could go about 4 days without washing my hair without it getting oily. Other than that as I mentioned, irregular (but light) periods at first. I would say that I would def go back on Spiro at a low dose to prevent all the hair loss if the Accutane doesn't work out but I am crossing my fingers that it will! I do believe that spiro greatly helped me control my acne, just didn't eliminate it completely...who knows if it would have if I had stayed on it for longer. This medication def takes a lot of patience that at 26, I just don't have anymore of when it comes to acne! Hope this helps. Lisa
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June 15, 2013
Finally a perfect treatment!!

Pros:

Clears skin!
Reduces Oil
Little to no side effects

Cons:

It can take awhile to see results, but worth the wait if your acne is hormonal!

I've been on spiro for 5 months I have been taking 100 mg daily and am currently still at this dosage. I started spiro three months after completing my accutane course. Unfortunatly I broke out after the accutane. I started the spiro and started to clear up after a month of use. Since then I'm not getting cysts or big pustular acne. I get a couple white heads here and there but the full benefits of spiro can take up to 9 months to show themselves. So I'm looking forward to having clear skin long term!! UPDATE: I've now been using Spiro daily for 14 months now. Still at the 100mg dose. It's managing to keep my skin nice and breakout free. I can't thank this medication enough. It completely rid me of the paranoia and fear of looking in the mirror in the morning and not knowing what I was going to face. I will admit I get a white head every couple of months. That's nothing to complain about! I do not have any side effects from the medication at all. All my blood results have come back perfectly. I love it!
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April 9, 2013

Pros:

Clears skin.

Cons:

Takes a while to work. I had an initial breakout. My skin seemed red and irritated at first.

I had a hard time finding a review that seemed to cover all the bases when I was debating going back on spironolactone. So here is my review.. I hope to help someone looking for answerers. So Last summer starting at the end of August I was prescribed Spironolactone, doxycycline, and epiduo gel. I didn't use the gel much but I took the pills everyday like I was prescribed. 75 MG of spironolactone a day and 100 MG of doxycycline. My acne just got a lot worse and I had it in places where I never really broke out (which seems to be pretty common) the breakouts were near my jaw, chin, cheeks, and neck. Which seemed strange because those areas are a popular area for hormonal acne. (and hormonal acne is what spiro is suppose to help with). Nonetheless it made mine worse. I was on it for a month or two..I'm not sure exactly how long it was, at the time the pimply days just seemed like forever but now looking back I think it was less than two months. Anyways, I stopped taking it because I thought it just wasn't the pill for me. While I was off the medication my initial breakout that I got from spiro went away but my skin was still not the clear skin I was seeking out in the first place. In February, after reading MANY reviews that mentioned an initial breakout I decided I would give it another try. So its been roughly 1.5 months and my skin had improved a lot. Within the first 3 weeks I may have experienced a small initial breakout but nothing like the first time. I still had slightly irritated skin within that time as well. However my skin is glowing now. I still have a few pimples but nothing like before and I am still in the beginning phase so I know I will still see improvement. I am also on tretinoin cream as well. I should also mention I am not taking the doxy.. I just don't feel I needed it and plus now I have a backup when a UTI hits me hard. ANYWAYS. Spironolactone works, maybe not for everyone but for many it does. If you look through the revi
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October 20, 2012

Pros:

WORKS!

Cons:

potassium deficiency

Ok, so I had REALLY bad hormonal acne. I never had acne until I had PCOS... and then all hell broke loose on my face. After struggling for a while, my dermatologist put me on doxycycline first and then spironoactone before putting me on accutane...10 Luckily for me, the combo of spiro+doxy+birthcontrol pill WORKED PERFECTLY. I no longer break out.. what so ever. I get maybe one pimple a month. I'm so relieved I didn't have to take accutane!
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September 23, 2012

Pros:

Cheap, small pill easy to take
can be on it long term.

Cons:

broke me out in places Ive never broke out before

I had a very stupid dermatologist that anything I asked about she would tell me its ok to go on. Thats how I ended up trying spiro. I started with 25 mgs for 2 weeks then 50 for two weeks then finally 75 for about a week. I didnt seen any improvements and I didnt see improvements in my oily skin either so I decided to stop. BIG MISTAKE. A week after, which just so happened to be right around my period, I broke out like I never broke out before my period ever, I broke out on my neck and chin and upper lip( my chin and upper lip are places I never ever broke out before especially my upper lip area.) It's been a little past a month since I stopped and I'm still getting breakouts on my chin especially around my period. I'm not totally against this drug if you have a dermatologist that knows what they are doing and if you stick with it. I recommend that if you go off of it to slowly do it and not do it cold turkey.
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January 22, 2012

Pros:

Cleared large zits on back of neck and back

Cons:

Broke out at first for 2 weeks
Severe nausea after working out

Started taking 3 pills a day but after 3 weeks was not seeing a lot of improvement. Dr upped my dose to 5 a day(125) and I started getting really nauseous after running. Did start to clear my acne however. Anyone else get nauseous?
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November 3, 2011

Pros:

Cleared up acne pretty well
Worked better than antibiotics

Cons:

Fatigue
Taking pills every day
Frequent Urination

I have tried EVERYTHING for my acne. I have had stubborn acne (pretty frequently cystic) for about 13 years. I am now 26 years old and have also gone through the torture of accutane about a year ago. Accutane was pretty difficult to get through, but in the end it worked dramatically. I have now been off of it and everything else for about a year now and my acne is now coming back (not as badly, but it's back, even cystic acne). I now have depression, anxiety and am on medication for that also. My doc thinks its probably from the accutane, but no one can be sure. I just started treating my acne now with Spiro and so far, so good. I've been on it for about three weeks so far and its cleared it up I'd say about 60% already. Hopefully this works completely, but everyone's feedback about it gives me hope. Thanks guys. Any questions about my accutane experience, let me know.
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July 8, 2011

Pros:

Don't know yet

Cons:

Initial breakout?

I recently started this medication. Went from 25 mg up to 75 mg where I am currently at now. I have only been on it for three weeks and I am havig the WORST breakout !! Has anyone experienced this ??? Is it normal ? How long does it last? Please give feedback. The derm says to stick it out but this is horrible.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.