Antiandrogen
Reviews
4.1
1330 Reviews
Antiandrogen
Efficacy
68%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Antiandrogen
Side Effects
High
Antiandrogen
Acne.org’s Real World Take
“Spiro” has been shown to work in a real and noticeable way most of the time. However, messing with hormones is messing with hormones and it’s best to proceed with caution.
Antiandrogen
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Spironolactone
Compare To Other Treatments
5
51%
4
28%
3
10.1%
2
4.9%
1
6.1%

Used Spironolactone? Rate It:

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February 21, 2008

Pros:

better facial skin all around!!!

Cons:

none, except for maybe having to take a pill
1-2 times a day

I have had rally horrible cystic acne on my chin for about the last 10+ years, consistently.....one pops up just as the others recede, and it's a never ending story...... I had tried antibiotic) benzaclin, birth control but NOTHING worked. As everyone else says, within the with 2 months I had a HORRIBLE breakout....probably the worst in my life. But once it cleared up, it cleared up for good! first I was 25mg, then 50 mg, and now 50 mg twice a day. I never thought ANYTHING would heal my acne. Spironolactone is amaizng! A wonder drug for hormonal acne. I reccommend it 105% My new cleansing plan is 50 mg of spiro in the AM along with probiotics & garlic capsules, and the same repeated in the night before bed. And I also wash my face in the shower with Cetephil Antibacterial Soap and the combo works WONDERS!
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February 9, 2008

Pros:

Fewer breakouts, reduced redness and irritation

Cons:

Fatique and dehydration

After trying a variety of acne medications (not only over the counter but also prescribed by my derm), incuding oral and topical, Spironolactone seems to be working the best. My breakouts appeared to be hormonal, however after a year of being on the birth control pill YAZ, my derm concluded that Spironolactone would compliment the effects of YAZ and overall balance my hormones. I stil break out, but episodes are fewer and further between. Does anyone know if consistently taking both YAZ and Spironolactone will eliminate my blemishes all together? Also, I was my face with Neutragena Oil Free face wash, does anyone know of anything better?
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January 22, 2008

Pros:

no more oily skin, smaller pores, no more breakouts

Cons:

makes you pee alot

I have had acne since I was 11. I have tried everything including accutane. once i was off accutane about 1 year and i would get more breakouts. About a year ago i started getting cysts and went to my gyno she put me on 100mg twice a day and lo estrin. This has worked miracles on my skin. I have been on this for a year now and I have not had a breakout in about 6 months. I also use differin gel. Its consistent and your skin is practically flawless. Dont give up this might be the answer for you too.
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January 6, 2008

Pros:

breast size increased, thinner body hair, less oil, diminished almost ALL of my acne

Cons:

took a very long time to see results. must take on a regular basis - if i'd skip a day or two, i would break out. Since it also affects blood pressure, I initially noticed dizziness and trouble exercising (this eventually went away).

I was prescribed spironolactone with differin gel about seven months ago at 50 mg/day. I broke out severely at first. After two months, I saw such little improvement that I went back to the doctor and raised my dose to 100 mg/day. Even then, I still broke out just less severely. It was only recently (about 4 months after raising my dosage) that I saw the improvement I'd heard about. I'm so happy I kept up with the product. I was told I would see full results in three months, but it was really after six. I would strongly encourage anyone battling hormonal acne to try spironolactone for a long period of time! Almost simultaneously, my breasts grew, my face became less oily, and my breakouts had VASTLY improved.
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November 12, 2007

Pros:

THIS IS THE ONLY ACNE MEDICATION THAT HAS EVER WORKED. MY SKIN HAS NEVER LOOKED THIS GOOD!!!

Cons:

took 3 months to really work well. Not easy to find a Dr. to prescribe it.

This medication transformed my skin. I didn't just get rid of my acne, I got BEAUTIFUL skin!!!
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October 30, 2007

Pros:

It is the only drug that ever has worked for me!

Cons:

Was extra tired the first couple mths.

I used to get terrible back acne and chest and cystic acne on my chin and jawline. I am 35. I have been taking 100mg of spiro since Jan 2007. It is a miracle what spiro has done for for my skin. All summer I was in tanks and sundresses! Lovely.
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May 26, 2007

Pros:

My skin is clear, not oily, my period is regular again, and I don't have leg/ankle edema at the end of the day anymore!!!

Cons:

If I drink alcohol, the combination makes me pee like crazy. Sometimes I have to go to the bathroom in the middle of the night.

I had moderate, non-cystic acne in high school. I went on accutane when I was 17 and it cleared my skin up great. No one in my family has had cystic acne. Then, all of a sudden, when i was 24 I started getting cystic acne. I would get 2 or 3 BIG nodulo-cysts a month. They would take 6 months to come to the surface and would scar. I went on accutane again for 8 months, which helped somewhat, but I was still breaking out while on the accutane up until the last month on it. I was really demoralized. I was also having a lot of problems with bleeding when I wasn't supposed to while on birth control pills. Then, 3 months ago my derm put me on 50mg twice a day of spironolactone. This stuff is great!!! My skin is PERFECT again, dry, and my periods are normal again. I've also stopped getting ankle edema by the end of the day. I wish I had tried this sooner. I would recommend this to any woman who has adult-onset cystic acne.
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April 7, 2007

Pros:

IT WORKS!!

Cons:

None. I experienced NO side effects.

I developed some adult onset acne around when I turned 26. It started out a just a couple big ones a month which was traumatic enough. A year later I had cystic acne. I was getting 5 or 6 big cystic pimples a month for a few months and hating my face and my life when I decided enough was enough. The first dermatologist I went to prescribed Sulfamethoxazole/Trimethoprim, Klaron and DIfferin. I was on that regimen for 3 months and my acne was only getting worse. I was ready to go on Accutane when I went to another doctor who prescribed me Spironolactone. Even at the low dose she prescribed (25mg/day) it was unbelievable how fast it cleared up my skin. After a month and a half on it, I went off of the antibiotics altogether. At this point, my skin feels great, just like it did the first 25 years of my life. I haven't gotten a pimple big or small in 3 months! Now I'm just waiting for the scars to fade. And there are no side effects at all!
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March 17, 2007

Pros:

WORKS FOR ME!

Cons:

NONE!! Seriously...no bad side effects for me, except the first few months I had some spotting in between periods

I have NODULAR ACNE...or HAD it...very bad. I thought Accutane was my only choice..but I thought I would give Spiro a chance after praying and praying. I first started with 25mg but didnt seem to do anything, so I asked my doc to up it to 50 mg, so I take that once a day at night w/ food and thats it and I have NEVER EVER been so clear in my life! I'm 21 and suffered since I was 12. I now just get occasional nodules, and my back and shoulders are clear! It took about 3 months to start working, but WOW this is an absolute answered prayer for me. ASK YOUR DOCTOR ABOUT IT! They will let you know if its safe for you (most likely is!) and you just might see a huge change, check it out! Best of luck!
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December 1, 2006
I am 43 and have tried everything under the sun for my acne and very oily skin. The BC pill helped and I stayed on that for years but it gave me migranes. So when i had to get off of them, my skin became more oiler than ever. The acne was bad to. My skin tone is a reddish tint so it never really looked clear. The oil just makes it look worse, so to make a long story short after trying everything else, my dermatologist suggested that we try this, 25mg twice a day and it seems to be a wonder drug. Its been 2 1/2 mos. My skin is ALOT less oily and the acne has cleared. I noticed a real difference after 1 mos. I love this medicine. By all means try this small dose. It does work. Drink lots of water. I have also started using a primer before i apply my foundation and that makes my skin look smoother.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.