Antiandrogen
Reviews
4.1
1326 Reviews
Antiandrogen
Efficacy
68%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Antiandrogen
Side Effects
High
Antiandrogen
Acne.org’s Real World Take
“Spiro” has been shown to work in a real and noticeable way most of the time. However, messing with hormones is messing with hormones and it’s best to proceed with caution.
Antiandrogen
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Spironolactone
Compare To Other Treatments
5
51.1%
4
28%
3
10.1%
2
4.9%
1
5.9%

Used Spironolactone? Rate It:

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October 27, 2009

Pros:

Works wonders!!! Cleared up my skin in less than 3 months of use! So far the best thing I have tried!

Cons:

As others, I do have to pee more day and night but I got used too. I also feel more tenderness on my breast and the first month acne was worse before clearing up, but appart from that I haven't had any major side effects.

I have been on spiro for almost 3 months so it might be too early to make comments on possible long term side effects but so far it has work amazing! I have struggle with acne all my life, taking antibiotics, topical creams and gels, I even tried Accutane wich work for about a year when I started to break again. My dermatologist suggested I might have hormonal acne so she started me on this pill. I've barely noticed any side effects other than my skin clearing remarkably. I will suggest if you have the chance to try it, it has change my life!
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October 26, 2009

Pros:

Spiro has cleared up my skin on just 75 mgs. I also haven't noticed any problematic side effects that drinking more water doesn't take care of. I don't get stomach aces or other problems like I did with antibiotics.

Cons:

I need to drink a lot of water. I do have to pee more ... but I have always been somewhat like that. I initially got dry eyes and dry mouth ... but drinking more water fixes this.

If you have hormonal acne, this will likely work. You don't know until you try. And everyone has different side effects, so again you don't know until you try. It took 2 months or 8 - 10 weeks for this medication to start working for me ... 3 months before I had tapered off my antibiotic because of the stomach aches ... which caused my skin to flare ... but also showed my derma that my acne was likely hormonal. For me, it is important to control my acne which is pretty severe even if there are some side effects b/c I have a problem with picking my skin when I get stressed out -- which happens a lot because I'm in grad school and am a perfectionist. I regret the day when I was a teenager when I thought picking would fix my face and get it out. That was a bad idea ... especially because my acne seems to be permanent (I am now 27). This forum helped me when I was starting out using this. It gave me hope that it might work. Thanks everyone.
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October 23, 2009

Pros:

EASY! I just take a pill, wake up with clear skin and I can end the day without a breakout. The best part is I can finally use a simple wash (cetaphil) and a simple moisturizer (oil of olay) and that's it!! And bigger boobs which is fantastic!

Cons:

It did make me dizzy so I had to stop taking it in the morning/afternoon and started taking it at night but don't find that I have to wake up to pee a lot as others complained about. It also made me a little more emotional for the first couple months

I'm very pleased with the results of this medication. I'm in my mid-20's and have suffered moderately severe acne/cystic acne since I was 14 and have tried EVERYTHING! I've been on 50mg. for about 4 months now and have finally started seeing results (it does take a while to kick in) I'm very hesitant about increasing my dosage and can't take birth control because it makes my emotions go haywire but did need something else to go along with it so my doctor put me on retin-A (the non-drying form) once a day which is amazing as well. Sooooo....bottom line- give it time!
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October 22, 2009

Pros:

Amazing!, after 11 years of dealing with acne and trying everything, I finally found a doctor that had me try this. It took about 3 months for it to start working for me but once it did I couldn't believe it (absolute miracle!!!!!)

Cons:

it does make you pee alot, my boobs grew a full cup size. Nothing bad like all the other things I've tried in the past. I am terrified to get off this when I want to get pregnant since it seems everyone gets acne again once off it

I wish I would have found a doctor who put me on this years ago! now my only issue is all the horrible scars from before.
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October 19, 2009

Pros:

Cleared up my acne when nothing else workedl. I am 56 and have suffered with cystic acne for many years. I'm currently on 75 mg. daily and I am very satified with the results. It took several months to kick in. Good luck!

Cons:

none

It's been amazing for me!
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October 19, 2009

Pros:

It will clear up your female hormonal acne and yes, your boobs get more full. My mood is elevated.

Cons:

light-headed occasionally due to lower blood pressure (stand up slowly and take care of yourself-pretty simple)

I began taking spironolactone at the beginning of 2009 along with birth control. My face cleared up within a month and I enjoyed nice skin until this summer when I stopped taking after I lost my health insurance. Went to see a P.A. at my University and told her I wanted spironolactone and YAZ because the combination is very effective for me. Back on 50 mg of spironolactone along with YAZ as of the beginning of this month. Guess what? SKIN IS CLEAR AGAIN! This works-it is the only think that has worked for my hormonal acne. Yes, the first week is tough with adjusting to the BC and Spiro-you are moody and tired but realize that the meds are not making you crazy. Your hormones are balancing which EQUALS CLEAR SKIN!! Good luck everyone.
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October 16, 2009

Pros:

Cleared up my skin.

Cons:

Dry hair and hair loss.

Gee, too bad it's having an effect on my hair. I've been taking it for 6 or 7 months now and noticed the effect it was having on my hair in just the last several weeks. At first it was just dryness, but now it's literally shedding quite a bit. It's done really well for my skin, but my hair is just as important. Looks like I'm going to have to pull myself off it.
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October 12, 2009

Pros:

It has cleared my acne. I've been on it for years now at a low dose. I have tried to go off it but break out when I try so I don't try anymore.

Cons:

I don't have any

People have no idea I have an acne issue. I have had to hide from mirrors/pictures for years and now I only worry about my hair. This drug has given me a normal life. I would highly suggest you try it.
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October 11, 2009

Pros:

This stuff works! Cleared up my cystic acne in a couple of weeks. Appetite suppressant: after taking it for a couple of months I really lost my appetite and lost several pounds (could also be a con depending on your perspective).

Cons:

Frequent urination, anxiety about using a chronic oral medication for acne that really isn't indicated to treat acne, worry about blood pressure/potassium levels.

I developed adult cystic acne in my mid-thirties. I developed cystic zits that would be huge, red, and would last for weeks, and would scar when they finally resolved. My dermatologist put me on spironolactone and topical Differin and Yaz and I noticed a huge difference after about one month. After taking the medication for two months, I had zero breakouts. I stopped taking the medication for a couple of months because I was afraid of taking a chronic medication for acne, but within 2 months my face was back to bad breakouts. So, I started taking it again last week hoping that my face will clear up again. Having clear skin is more of a priority to me right now than worrying about the side effects of long-term usage.
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October 11, 2009

Pros:

It took about 2-3 months, but my face looks better than it has in a very long time.

Cons:

none

I am 39 years old and have suffered from adult acne since I quit taking birth control pills 2 years ago. I truly recommend this product. I was really oily and have cyst acne, now I am no longer oily and my acne has nearly cleared up. This is really affordable, at about $8 a month. Which is great compared to the topical treatment I was using at $200. I do not have any side effects from this medicine. Highly recommended!

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.