Antiandrogen
Reviews
4.1
1326 Reviews
Antiandrogen
Efficacy
68%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Antiandrogen
Side Effects
High
Antiandrogen
Acne.org’s Real World Take
“Spiro” has been shown to work in a real and noticeable way most of the time. However, messing with hormones is messing with hormones and it’s best to proceed with caution.
Antiandrogen
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Spironolactone
Compare To Other Treatments
5
51.1%
4
28%
3
10.1%
2
4.9%
1
5.9%

Used Spironolactone? Rate It:

Choose from 1 to 5 stars
January 7, 2008

Pros:

It seems like my skin is producing less oil. The pimples I get are more towards the surface of the skin, and not as deep and cystic as they were before.

Cons:

Amount of pimples hasn't really changed, just the size. Also a few pimples developed on my forehead...where I never break out.

I've had acne since 12, mild hirsuitism since 16, and I'm now 25. I was on spironolactone about five years ago, and it worked until I went off of it. Since about six weeks ago, I started out with 25 mg/day and didn't see any significant improvement, maybe a slight decrease in irritation/redness. I also got my period on time, which is rare. Then,a few weeks later I got the dosage bummped up to 50mg/day. Again nothing amazing. So about a week ago my doctor put me on 50mg/twice a day. I still haven't seen any major improvement yet, but I have hope since this drug worked before. Question for anyone who has taken this drug long-term and at a higher(>50)dosage. How long did it take to start showing a significant improvement in acne and/or hirsuitism?
January 7, 2008

Pros:

decreased oil production,controlled acne, lost 5 lbs!

Cons:

felt dehydrated

This is the ONLY thing that has ever helped my skin. Significantly regulated my oil production and lessened my body hair. Nearly eliminated the cystic acne I had suffered from for 15 years. Would get small whiteheads (which I never had before), but these would clear quickly. Since this is a diuretic, as an added bonus I usually lose 5lbs each time I restart this prescription (have been on it 2x). The formula that worked for me was 100mg spiro, solodyn, retin-a micro & washing with Glytone essentials. Did cause me to be extremely thirsty.
January 7, 2008

Pros:

clears skin and minimizes hair growth (esp. on chin, etc.)

Cons:

tired, peeing a lot, taking a pill everyday

If nothing else has worked for you (especially topical) and if you've developed acne post-adolescence (like me), it's definitely worth a try! I am back on it after about 6 months off (due to moving, changing doctors, insurance, etc.) but it works for me, and I can't imagine going back. It makes me sad to read about other peoples' experience, looking in the mirror and wanting to cry, avoiding social situations...but there's hope!
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January 6, 2008

Pros:

breast size increased, thinner body hair, less oil, diminished almost ALL of my acne

Cons:

took a very long time to see results. must take on a regular basis - if i'd skip a day or two, i would break out. Since it also affects blood pressure, I initially noticed dizziness and trouble exercising (this eventually went away).

I was prescribed spironolactone with differin gel about seven months ago at 50 mg/day. I broke out severely at first. After two months, I saw such little improvement that I went back to the doctor and raised my dose to 100 mg/day. Even then, I still broke out just less severely. It was only recently (about 4 months after raising my dosage) that I saw the improvement I'd heard about. I'm so happy I kept up with the product. I was told I would see full results in three months, but it was really after six. I would strongly encourage anyone battling hormonal acne to try spironolactone for a long period of time! Almost simultaneously, my breasts grew, my face became less oily, and my breakouts had VASTLY improved.
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January 1, 2008

Pros:

Flat stomach

Cons:

Make me feel thirsty all the time. Have to drink tons of water to not feel dehydrated, Taking a pill every day.

I have been taking spiro for about three weeks. I definitely saw my belly get super flat but I havent notice much improvement in my acne. I was taking 100mg every day but I upped my dose to 200mg. I will probably slow downt to 150mg baceuse 200mg might be too much and I think a higher dose will not accelerate the process. I will defenitely keep taking it since it seemes like it starts working after month 3. Im also having the Smooth Beam laser done every month. I had my first treatment last month so I'll wait to see how things work all together. I was thinking about getting a prescription for Yaz since I will need the birth control.
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December 23, 2007

Pros:

I have lost some weight since I started taking it...

Cons:

my face is breaking out worse than ever

I started taking it 3 wks ago and have upped the dose to 100mg this past week. I had to go off birth control pills 6 months ago because of melasma and my face has been getting worse since. I heard about spiro and asked my doc for it to see if it helps me because my acne seems to be hormonal. Within the 1st week of taking it, I got a ton of bumps on the lower half of my face, big and small - and they seem to be multiplying and not getting any better. Before taking it, the most pimples I would have on my face were about 4-7. My face looks worse than ever! I have read that some of you have had the same problem - but haven't seen any posts from the same people with an update on it it has gotten better. Please - any input would be helpful because I am so depressed right now - I don't even want to leave the house. Is 100mg a good dose to be on?
December 22, 2007

Pros:

i have noticed drier skin and my chin flakes now every day.

Cons:

Haven't noticed an improvement. I have been on it for 3 weeks and I'd say things have only gotten worse.

I am open to giving it more time, but after 3 weeks, I can say I don't feel it's working.
December 7, 2007

Pros:

Helps a lot with oil

Cons:

had a tiny breakout when I first started, peeing a lot, taking it every day

I really liked this stuff. I liked not having to wash my hair all of the time. My oil was helped, but it didn't dry me out. I really didn't mind peeing all of the time since I felt like I was losing weight. I was also taking Yaz so I was taking 125mg of spiro all together.
December 1, 2007

Pros:

Works!

Cons:

Took a few months to start working/irregular periods/diuretic/hard to find a doctor that will prescribe.

Only thing that has worked long term for me. Tried everything (homeopathic/retin-A/antibiotics/accutane etc.)-nothing worked except spiro (100mg/day). Now trying to get pregnant and need to go off of it-looking at the site for alternative treatments.
November 16, 2007

Pros:

Spironolactone works great. After having acne in my teens, then in my thirties with the deep "undergrounds" sprironolactone cleared my skin beautifully. I couldn't believe it after I used laser treatment, years of actibiotics and topical creams.

Cons:

The downside, it caused severe breast tenderness. But I found if I took 500 mg of vitamin e along with the pill, I experienced no breast tenderness at all.

I think it is really short of a miracle. I have been taking it four a few years now. Intially I began with 25 mg have worked up to 100 mg then down to 25 mg. I don't know how long one can take this medication.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.