Antiandrogen
Reviews
4.1
1330 Reviews
Antiandrogen
Efficacy
68%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Antiandrogen
Side Effects
High
Antiandrogen
Acne.org’s Real World Take
“Spiro” has been shown to work in a real and noticeable way most of the time. However, messing with hormones is messing with hormones and it’s best to proceed with caution.
Antiandrogen
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Spironolactone
Compare To Other Treatments
5
51%
4
28%
3
10.1%
2
4.9%
1
6.1%

Used Spironolactone? Rate It:

Choose from 1 to 5 stars
September 20, 2010

Pros:

Cleared Acne, lost some water weight, tolerable side effects.
Cost is CHEAP, compared to other medications.

Cons:

For the first few weeks, I was VERY tired; but then, after the first few weeks, the tiredness went away.
I have to drink lots and LOTS of water so that i don't get dehydrated and get a headache; as a consequence, i pee SO much, like 10 times a day, atleast.
Slow progress; it took me about four months to see any significant results.

I just want to encourage anyone who is just starting spironolactone and don't seem to see any fast improvements... this medication takes some time so please be patient. I read many reviews on this site that told me to be PATIENT, and i am glad that i listened and persisted because after about 4 months in, i am reaping the benefits! :) Spironolactone is working for me; i don't have any 'active' pimples on my face (for the first time in how many months???) and i am now being patient about the scars fading... good luck and hope for the best. acne sucks and i know how it feels.. be patient.
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August 16, 2010

Pros:

-I almost never get acne anymore
-I never get cystic acne anymore
-Lighter body hair
-Lost water weight
-Less oily skin / hair

Cons:

-More light-headedness when I stand up quickly
-Some doctors require that you get your blood drawn regularly to check electrolyte levels (I have only had to do this once in 1.5 years)

I first heard about this in Elle magazine, and I am so glad I asked my doctor about it (though she had to look it up, as she'd never heard of it being used this way). I have been taking 50mg/day for about 1.5 years with no problems and consistent results. Though I've never had terrible acne, I always got it hormonally. And whenever I got acne, I would pick at it (check out [link removed] for more info). This would create a vicious cycle in which picking would lead to more acne, etc. When my skin was bad, I'd get depressed, become a recluse, and buy ridiculous, expensive skin products in hopes that they'd save my skin. Spironolactone is the only thing that has helped me break that cycle (and I've tried everything from OTC washes to extreme diet changes, only to realize that my acne is completely hormonal). My skin is now beautiful all of the time. I no longer wear makeup to bed with my boyfriend, and I don't have to hide in shadows when I walk down the street. I don't dread stores with fluorescent lighting. The list goes on! Why not give it a try? Give yourself a chance to start living your life fully. For $20-$30/3 months, it's well worth it.
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June 10, 2010

Pros:

less oily
smooth skin
loose some weight
1 pill a day = 100mg

Cons:

initial breakout
takes about 3 months to see results

This is the best thing I ever took...l was getting severe large painful cystic acne around my chin. which is mainly hormonal. I've tried everything on the market and nothing seemed to work. I don't use any benzol peroxide or any salycic acid on my face...Just use a mild cleanser now with an oil free moisterizer day and night..It did take 3 months to see a significant improvement but it was worth it. I too was discouraged by the results at first but the postings on this site kept me going..Please do not give up...I have been on 100mg a day now for 4 1/2 months and rarely have any breakout even during that time of the month...
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December 20, 2010

Pros:

Definitely cleared me up!

Cons:

Bit inconvenient to take the pill every single day, but it is worth it
Had to wait couple of weeks to see complete effect

I originally took this along with BC when my doctor and I concluded that my acne was hormone related. I went off Yaz because it was causing weight gain and clots, and I was worried that I would see my acne return even with Spiro, but I went off and hardly saw a difference! actually saw it improve. I use it now along with Atralin cream, and the combo give me perfect skin (breakouts here and there). I paid $0 because my insurance is amazing.
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May 11, 2012

Pros:

-LESS OILY SKIN/HAIR
-STOPPED PAINFUL CYSTS IN THEIR TRACKS AFTER A 2 WEEKS.
-FEELING SO MUCH BETTER ABOUT MYSELF!
- WAY LESS MAKEUP

Cons:

MORE TRIPS TO THE BATHROOM BUT I DONT REALLY MIND THAT TO HAVE THIS ACNE FREE FACE!!!

I'v struggled with acne since i was 12... It really has taken a toll on my confidence. I always felt like i had this permanent ugly mask on, it really sucked to feel so disgusting & having no control over it. I have been on accutane, doxy, mino, bactrim, proactiv, acanya, atralin, ETC ETC ETCCC!! drank tons of water, ate healthy great hygiene bla bla bla NOTHING worked like spironolactone. accutane helped for about 2 years when i was 19 then boom full blown acne came back at 21. it was so bad. so embarrassing, even to show my dermatologist i even seen in her face she knew it was so bad... she would do chemical peels and stick me with those needles to try to get it to go down & THEN i broke down in tears. --i know things can be ALOT worse-- you must always remind yourself that!!!!! but emotionally & physically i was hurting. it took over my life. i am a young happy outgoing girl with pretty friends and a handsome boyfriend, & it doesn't bother them at all but it kills me to be seen with acne all over my face i just wanted to hide from everyone. I even became petrified of little kids because they would always ask what it was. just always felt like a freak show deep down but did a great job acting like it didnt take over my life and like didnt become obsessed with it and trying to cover it 24-7. and then i was like enough is enough. i refuse to let this friggin acne win and take away my social life and my confidence and my beauty and everything else i read acne.org reviews almost everyday hoping to find some help. AND I DIDDDDD!! I went to a new derm & he prescribed me it on the spot, 100 mgs a day. THANKS TO EVERYONE WHO WROTE ABOUT SPIRO!!!! THANK YOU SO MUCH FOR REVIEWING! I felt so helpless in my world full of friends & family with normal skin! i'm so thankful for this website & everyone else like me... ***GIRLS DONT GO ON ACCUTANE GO ON SPIRO!!!! PLEASE!!!!! TRUST ME.*** & accutane can cause women to be
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February 14, 2012

Pros:

*it works!!
*severely lessens cystic acne/milia/pimples
*easy to take
*reduces oiliness
*minimum/no side effects
*also helped get rid of my migraines??
*gave me my confidence back!

Cons:

*must be PATIENT- this is key!!! for me it took almost 4 months to see results
*thirsty a little more often
*pee more (it's a diuretic)
*weight loss (although this may not really be a con)
*get your pottasium levels checked just in case

I have had mild/moderate acne on my face, chest, and back since high school. I had always been able to pretty much keep it under control... and then I turned 21. WOW. New blemishes every day, painful, huge, take-months-to-disappear cysts on my forehead and jawline, as well as tiny little skin-colored bumps (milia) along my cheeks and T-zone. It was miserable-- I would not be seen without makeup on, if I forgot my concealor at home I would freak out, I was terrified of pools, looking at my reflection in the car window, sweating... I know there are people out there with much more to stress about but it literally made me hate my life. I tried everything, from proactiv/tazorac/ anti-biotics/birth control/glytone/$$acid peels/microderm... NOTHING worked. Finally I took the time to research other options out there, thinking I would have to resort to Accutane. Thankfully I discovered this, went to the doctor, and got prescribed 25 mg/day (I am 5'5 105 lbs) along with retin-A gel to use at night. Over the course of a couple months, I moved up to 100 mg/day (50 at morning 50 at night). I didn't really see any significant change until about week 8. I still had massive gross cysts, but they healed quicker.. I was discouraged that it wasn't really working yet, but decided to wait it out and continued to take the spiro religiously. Well, now I am in my 4th/mo of taking it, and the difference in my face is night and day, and only getting better!! I used to have about 15-20 blemishes on any given day; now I have 2-3 at MOST. My pores are smaller, my skintone is more even, NO blemishes on my back or chest. My face still gets oily from time to time, but much much less than before- nothing face blotters can't fix. I must give some of the credit to the retin-A, which has definitely helped with the scarring and redness, but I know 90% of the change happened on the INSIDE, where spiro starts to work. PLEASE give this a chance, and be PATIENT, it won't happen over-night!
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May 2, 2010

Pros:

Gets rid of acne...period!!!

Cons:

None

I've been on every acne treatment under the sun, minus Accutane. Every antibiotic, every topical product, both over the counter and RX. Finally, after suffering for years with what I suspected was acne caused by hormonal problems, I went to a new dermatologist. She said, your acne is on the lower half of your face, you break out more just before your period, no other acne med's have worked...you have hormonal acne and need Spironolactone. I started with 25 mg/day for one month. Then went to 50 mg per day after that. Within 2 months my acne had began to clear and I'm now acne free! For the first time in years! I had no problems with this medication. This was about 5 years ago. I took it for about 2 years. Then went off it as I had been free of acne the entire time. I continued to be acne free until I had a stressful event. At that point I began getting a few acne cysts again. So, I went back to my dermatologist who put me back on Spironolactone and again...I'm acne free! My suggestion is...find a dermatologist who will give you this. I kept thinking, "Why are all these doctors treating my symptoms and not trying to treat the cause?" I knew my acne was related to hormones in some way! Especially since I never had acne until I went on a specific birth control and after that I developed acne cysts, mostly on the lower half of my face. And these would get much worse during PMS. This drug is the absolute best! It's cheap and it works. Who could ask for more?!
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November 13, 2010

Pros:

Drastically clears up skin
Face and hair significantly less oily
Decreases water weight/bloating
Improvement after 2 weeks of use
Inexpensive

Cons:

Occasional irregular heart beat and tightness in chest
Spotting in between periods
Fatigue and headaches (first few weeks)

This medicine actually works!!!! Having suffered with acne for 13 years, I have been on every possible medication including 2 rounds of Accutane. When I was 15 I developed a rare skin condition called Gram Negative Folliculitus; caused from taking Tetracyclin for a pro-longed period. The gram negative formed a bacteria combined with severe cystic acne that dis-formed my jaw line and it was so bad, I was out of school for 6 weeks. I was put on Accutane to clear it up and it did, but my regular acne soon came back and never left. After years of tears, scaring and trying every prescription, online and homopathic natural treatment, I went to a new dermatologist for one last try. She prescribed me spironolactone and I could not be happier. I call it my miracle drug...if you have hormonal acne, this WILL work and you will see improvement after just a week. I have never been more happy with my clear skin! Now if only I can find a fantastic product for left over scars ;)
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January 21, 2017
Time and Patience
I am a 38 year old female who has had fluctuating acne for over 22 years. My acne piqued about 4 years ago. I'm talking persistent, mind numblingly painful cystic acne on my chin, jawline and unto my neck, they reproduced and had babies all over my face, forehead and anywhere there was room, including on top of each other (ouchie!!). My face was an oil field requiring face blotting every hour. I had been on the BP regimen for years prior but it did nothing for the the cysts when they came full force seemingly out of nowhere. I still thank the BP regimen for years and years of controlled acne, so no resiment here, it just wasn't a match for for my spastic hormones. I needed a systemic fix, not just topical. A sidebar to reflect on some facts of life: 1) We live in a society that demands a quick fix. You see it all over TV, radio, etc... But the reality is quite different. It took years and years of imbalance for your hormones to turn spastic for a plethora of reasons (age, genes, family history, environment, diet, etc). Your hormonal acne and the underworkings did not just suddenly happen although it feels that way. So give Spirinolactone at least that same amount of time to do its job. It's a systemic drug. It needs to be given months and months of tweaking with the dosage before you can expect it to work. 2) Manage your expectations. This med worked for me but it is not a miracle drug. I had a horrendous initial breakout once the dosage was increased. I was a hermit for months. I started at the lowest dosage and that did nothing for me other than make me go pee a lot. Painfully and slowly, my derm increased the dosage to the max allowed which is 100mg twice a day. That was 8 months ago. I continued to pee a lot, my oil production was cut by 90% , I had headaches, my period was coming every two weeks and my acne decreased by 85%. I was persistent. Even though I wanted to quit because I wanted perfect, glowing skin and microscopic pores right now (see bullet point #1 ;))! 3) At 8 months out with the 200mg daily dose and having been on this med for almost 2 years with incremental dosage increases, I now have zero oil which requires copious amounts a daily moisturizer (because I'm dry now 🙂). I still get a few pimples around ovulation and my period. I still pee a lot but I'm used to it now. Headaches are gone once my body got used to the increase in dosage. My period has normalized although my cycles are shorter but the flip side is that my periods are lighter. Win/win. 4) Quality of life: improved! I still have a few pimples but I'm ok w that. I have improved 90% overall and I can live w that considering where I started. Conclusion: Be patient ladies. Hormonal acne is vicious and soul sucking but you are not alone and you can push through! These blogs and positive reviews inspired me and helped me suck it up on days I just wanted to stay in bed and eat lime flavored chips all day long 🙂. I promised myself I would pay it forward and write a review once my acne was under control. If only to inspire one person to push through and be persistent with the medication, I feel like it was worth it. Each individual person has to reach their own conclusion on the risk/benefit of any drug they are taking. There is no risk-less medication out there, do your due diligence, inform yourself and be comfortable in your decision. Most importantly, remember that you are not alone and there are others out there dealing with the same thing. I'm sending you all happy vibes and a wish for glowing, acne free, with maybe the occasional little pimple 😉 Skin! Persevere, you got this!
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February 6, 2017
Hi! Thank you so much for this amazing review. I was wondering if you got an initial breakout with this and if so did you get it right away or later on? I am 3 weeks in and haven't had one yet.
December 11, 2017
Hi i’m also wondering if you had a purge? Also, do you think this took so long because of the severity of your acne or having to let your body get used to it?
December 28, 2017
Sorry ladies, I apparently don't check this often enough and am just now seeing this 😬. I was started on 25mg and had no purge with that, also had no improvement with that dosage. Once I was increased to 100mg, I had a horrid purge. Embarrassing and painful but I pushed through 💪🏽. I think this took so long to work due to my hormones being really out of whack and getting the correct dosage which took about a year and a half. I was super patient and it was not a fun ride, but it can be done 😁. Hope this helps!
December 28, 2017
Sorry ladies, I apparently don't check this often enough and am just now seeing this 😬. I was started on 25mg and had no purge with that, also had no improvement with that dosage. Once I was increased to 100mg, I had a horrid purge. Embarrassing and painful but I pushed through 💪🏽. I think this took so long to work due to my hormones being really out of whack and getting the correct dosage which took about a year and a half. I was super patient and it was not a fun ride, but it can be done 😁. Hope this helps!
December 27, 2009

Pros:

clear skin, less depressed

Cons:

thirsty & pee alot

I am 25 years old and I have had hormonal acne sine I turned 20. I tried so many things just to be dissapointed and I have so many scars! have been taking 25mg a day for 3 months now. i had deep, painful cysts along with regular acne, but now i am 100% clear! I am so happy, i want everyone to know about Spironolactone! I can leave the house without wanting to cry because i felt like a monster. i will post photos soon!
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.