Antiandrogen
Reviews
4.1
1330 Reviews
Antiandrogen
Efficacy
68%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Antiandrogen
Side Effects
High
Antiandrogen
Acne.org’s Real World Take
“Spiro” has been shown to work in a real and noticeable way most of the time. However, messing with hormones is messing with hormones and it’s best to proceed with caution.
Antiandrogen
How to Get It
Have a dermatologist? Make an appointment to get this medication. Don't have a dermatologist? See The American Academy of Dermatology Physician Database to find one.
Read All About Spironolactone
Compare To Other Treatments
5
51%
4
28%
3
10.1%
2
4.9%
1
6.1%

Used Spironolactone? Rate It:

Choose from 1 to 5 stars
June 13, 2008

Pros:

works in a unique way

Cons:

Did not improve my complexion, but gave me lots of side effects: a lot of breast tenderness and irregular periods (every 2 weeks!)

I was only on the therapy for about 6 weeks because i couldnt tolerate the side effects. During the time i was on it, i didnt see an improvement in my oily skin and/or acne.
May 29, 2008

Pros:

Cleared acne, drastically reduced oil

Cons:

made me slightly dehydrated.

I have tried everything in the book - Birth Control Pills, antibiotics (for years) and every topical cream out there - this finally did it! It took a good 6 months to completely work, although, I did see great improvement prior to the 6-month market. FANTASTIC!!!!!
May 26, 2008

Pros:

It works.

Cons:

Frequent urination the first couple of weeks. Takes some time to work. I didn't notice much difference until after a month. I'm scared of the long term side effects and how it might affect pregnancy. Difficult finding a Dr willing to prescribe it

I've tried everything under the sun for acne and I found out that the best treatment is Dan Kern's regime, Ortho Tri Cyclin, and Spironolactone if you have hormonal acne. The combination of these three medications has made me 95-100% clear. My face used to be 30% covered in acne. Dan Kern's regime does a fantastic job on tiny pimples and decreases the overall number of pimples. However, it couldn't completely get rid of my acne problem. Ortho Tri Cyclin has helped tremendously. My friends commented on how my face was getting nicer and nicer. The combination of these two medications left me with pretty manageable acne, but it was still there and I still had pretty persistent acne on my back. After being prescribed sprironolactone, the acne on my back has completely disappeared and the pimples only appear when I'm stressed or eat badly. I've been prescribed 50mg once a day. Give it some time, it didn't work for me until after a month. Good luck :)
May 14, 2008
I am 39 and have been living with the fight of acne for 25 years. I have tried everything under the sun but nothing works. I switch doctors to try Accutane but he suggested Spironolactone because my hormones were somewhat elevated. I have been on Spironolactone for almost 2 months. I haven't seen much improvment as far as oil and was farirly clear for a few weeks. A few weeks ago I started breaking out really bad with cystic acne all over my chin and forehead. My doctor put me back on my antibiotic for a couple months until Spironolactone kicked in. I still haven't noticed much of a change in oil or the acne. Is this nromal or is this not going to work for me??????
April 8, 2008

Pros:

Godsend for my cystic acne, my skin is 90% cleared up after 4 months

Cons:

may cause dizziness

After my acne graduated to cystic acne thanks to stress... I was at my wits end, finally my dermatologist recommended going to an endocrinologist... she made my life hell but gave me a prescription after 5 weeks... within 24 hours, i saw a huge difference in my face, and within 24, it was a 100% difference i started off with 25mg once a day for two weeks, then graduated to 25mg twice a day for two weeks, then 50mg twice a day... since then, i've come back down to 25mg per day.. thats it... but it was a GODSEND!
April 7, 2008

Pros:

weight loss, less oiliness

Cons:

initial breakout, dizziness, constant thirst

I'm still waiting for Spiro to kick in. I've only been taking it for 11 days so I guess I shouldn't expect much so soon. My derm prescribed 50 mg/day along with 200mg/day of doxycycline. I've had a terrible initial breakout. My acne hurts and itches really bad. I can actually feel when a new zit is forming. I've suffered from cystic acne for about 6 years and have tried a lot of products. Hopefully this will work...It's so embarrassing to have acne! I'm a little worried about this initial breakout...hope it clears up SOON! I will update in a few weeks.
April 4, 2008

Pros:

so far none yet...

Cons:

Mouth is very dry and skin is breaking out Horribly!

I have been on this for about 2=3 weeks. My skin looks horrible! i, just like most of you, dont even want to go out of the house! and it hurts... my face actually hurts from all the acne on it! im just hoping that its just bringing it to the surface and it will all be over soon...
March 7, 2008

Pros:

Clear skin, a bit of weight loss,

Cons:

Excessive tiredness, dizziness and light headed

This works great. I have had acne since I was 12. I had used almost every single acne product on the market and nothing worked. I even did a stint with acutane and that worked at first but eventually the acne came back.I have been on Spironolactone for more than 3 years. I started out with 50 mg doses at 2x/day however am now down at 1x /day. I have noticed my skin has acted up since I have reduced the dosages and has become a lot oilier. I may try going back up 2x/day but then I am worried I will become depended on it. Ovreall, I would definitely recommend it if you are struggling with acne.
January 25, 2008

Pros:

significant oil reduction since i started to use spiro.

Cons:

irregular period...spotting.

ok, so since i started to use spiro, this will be week 3, i have noticed significant oil reduction and less cycstic acne. i had an initial outbreak just after one week, which was really horrible, but i kept my cool and stayed with the program. my face is starting to clear up nicely, with the exception of a few lingering cycstic ones. also, i've noticed blothces on the skin of my arms and abdomen area, i will see my derm on monday about this. if anyone has pics, please post them if you are able to. i would love to see the progress that anyone has made so far.
January 13, 2008

Pros:

Changed my life! Oil production and breakouts ceased within first 3-4 doses. I have only had one cystic zit in 4 months of use.

Cons:

Felt sextremely tired for the first 2 weeks. No other bad side effects.

I am 35 and have been battling my skin ever since I can remember. I suffered from cystic acne mainly on the chin as well as extreme oil production all over the face. There was never a day I didn't have a breakout or didn't have to use numerous oil blotting papers to degrease my faec. Every morning and night, I looked in the mirror to see what new had popped up and also see if the any of the old spots were getting better. No more obsessing over my skin since taking this medication! I can't explain how happy I am. I take 100 mgs per day and also use Differin gel .3%. My skin is drier all over my body, which is not a bad thing for me at all. The palms of my hands and feet, as well as my nails, are drier which is totally fine, too.

Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.