Topical Retinoid
Reviews
3.2
1910 Reviews
Topical Retinoid
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Prescription and over-the-counter adapalene share the same efficacy percentage due to non-specific research, but prescription strength likely performs better.
Topical Retinoid
Side Effects
Low
Topical Retinoid
Acne.org’s Real World Take
This topical retinoid medication provides partial relief at higher prescription dosages, but don’t look for complete clearing, especially at over-the-counter strength. Relatively affordable and comes with less side effects than tretinoin, the other affordable topical retinoid. As a bonus, it improves the look of skin and reduces fine lines and wrinkles a bit too.
Topical Retinoid
How to Get It
This is an over-the-counter treatment. Here are some places you can find it online.
Read All About Adapalene (Non-prescription)
Compare To Other Treatments
5
17.5%
4
30.4%
3
22.6%
2
17.1%
1
12.4%

Used Adapalene (Non-prescription)? Rate It:

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April 21, 2009

Pros:

does work for some people

Cons:

dries skin, makes red, used it for months and done allmost nothing. cost to much.dissapointing

try it, it may work for you but make sure you put it on befor bed,and use a moisturiser in the morning the reason i recomend this product is that i know alot of people who used it and got great results..as long as you use a moisturizer.
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April 16, 2009

Pros:

Works great! I was using Differin at night,Benzaclin in the morning & taking Doxycyclyne once daily. I had great results right away & my face cleared up in 1-2 months. I took the antibiotics for bout 2 months but I am still using Benzaclin & Differin

Cons:

Differin made my skin tight when I put it on. But I used it at night, so I didn't mind.

Invest in differin!
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April 8, 2009

Pros:

acne eventually clears, drying not terrible, no redness, mild

Cons:

starts out by making acne worse, much worse, drying to the point where it hurts to smile, but not at first

I never had acne, well maybe a tiny un noticible bit. So i used proactiv, after a few years of that it stopped working (my derm. says this is what usually happens) i use differin and after 2 or 3 weeks it started to get worse, and it was for a month or so. It is pushing the bad stuff out and you need to just wait it out. Now i use differin in the morning and evening and ziana in the night and i am gradually healing. To the point where my derm. said it is 50 to 60 percent better. I am pleased. BE PATIENT!!
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March 17, 2009

Pros:

Makes skin softer. I've tried gel and cream; cream doesn't work as good but it makes your skin SOFT+no need for lotion.

Cons:

Didn't do much for my acne. I used it for about 6 months. You're supposed to see results way before then, but I did not. If anything.

Look at the cons. If anything, it made my acne worse. I wouldn't recommend it. Try another retinoid.
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March 14, 2009

Pros:

Works for those who have patience, doesn't dry my skin out, does not smell, no residue

Cons:

Expensive

With Differin gel, your face will get worse before it gets better. You need to use it at least three months before you see results. That said, I was frustrated with the initial breakout, but remained determined to stick it out for at least three months. I'm really glad I did. I'm using Differin with BC pills and antibiotics to great effect. Whereas I used to get 3-4 new pimples a day, now I only get one a week and sometimes none at all. Without new pimples constantly forming, my red spots can properly fade. I'm very happy with Differin and find that I can even use it with BP (at the same time) without my face drying out or becoming irritated.
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March 8, 2009

Pros:

Cleared up acne after a while , not difficult to use, results within a week (varies)

Cons:

a bit on the expensive side unless you are insured.

I had mild acne before Differin. I use differin with another treatment: clindamycin. It really works. I've tried just about everything : neutrogena, clean and clear, bareminerals you name it. While clean and clear did work, it gave me a lot of white heads so as the others. I stopped using bare minerals because it contained sulfur which was not to be used with differin. For the first 3 days it seemed as though my acne got worse, and I was all "this isn't working, I give up." but after the three days, I stuck with it and I started to see change as the pimples shrunk and most of the small ones vanished! I have sensitive skin so I use the 0.1 Differin. For those of you who have said your acne has gotten worse, maybe it just isn't for you and or you have a lot of unseen acne beneath your skin that is being pulled up by differin, I read that this is SUPPOSED to happen so really, stick with it.
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March 4, 2009

Pros:

It's really been clearing up every type of acne that I have. The whiteheads, blackheads and cysts are all drying up

Cons:

My entire face is peeling for the past two weeks and is extremely red

I would recomend the .1% not the .3% that im on it's too drying!
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February 27, 2009

Pros:

Differin took a while to start working, but when it did it was great. It really helped me for the first 1.5 yrs i was on it

Cons:

the effectiveness definitely wears off after a yr and a half, but i guess thats to be expected. My acne came back worse than it had been prior to treatment. I also got sunburnt really bad really really fast on it.

It works well, but definitely not a permenant solution. I would recommed it for people in high school tho, it really helped me thru those yrs!! If u are going to use it you really need a good sunscreen at all times (especially in summer... but in saying that, im in australia so any additional photosensitivity is a problem in summer down here...especially if you're like me and used to never really burn, just tan...that definitely changed!!)
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February 26, 2009

Pros:

CLEANS POURS NO MORE BLACKHEADS SMOOTHS MY SKIN THIS AND IT SO EASY TO USE JUST APLY BEFOR YOU GO TO BED

Cons:

NONE

LOVE IT BOT IT IN MEXICO IT COST UNDER $ 20 AND YOU DONT NEED A PERSCRIPTION
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February 10, 2009

Pros:

It cleared me up 70% after the IB. My insurance covered it 100%

Cons:

I've developed an allergy after 4 months or so. Even a very small amount anywhere on my face made my eyes puff up like a newborn seal within a couple of hours and persisted at least a day. The exact same thing had happened to me with BP, too.

It may cause severe reaction.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.