Topical Retinoid
Reviews
3.2
1910 Reviews
Topical Retinoid
Efficacy
54%
Based on All Available Studies
Strength of Evidence
1
2
3
4
5
Note: Prescription and over-the-counter adapalene share the same efficacy percentage due to non-specific research, but prescription strength likely performs better.
Topical Retinoid
Side Effects
Low
Topical Retinoid
Acne.org’s Real World Take
This topical retinoid medication provides partial relief at higher prescription dosages, but don’t look for complete clearing, especially at over-the-counter strength. Relatively affordable and comes with less side effects than tretinoin, the other affordable topical retinoid. As a bonus, it improves the look of skin and reduces fine lines and wrinkles a bit too.
Topical Retinoid
How to Get It
This is an over-the-counter treatment. Here are some places you can find it online.
Read All About Adapalene (Non-prescription)
Compare To Other Treatments
5
17.5%
4
30.4%
3
22.6%
2
17.1%
1
12.4%

Used Adapalene (Non-prescription)? Rate It:

Choose from 1 to 5 stars
March 23, 2009

Pros:

acne bumps gone
nice skin!

Cons:

takes up to 3months to see change
dries skin out at first
makes skin worse BEFORE better

overall, it will make skin seem worse but its just getting all the gross acne out. over time it will make skin seem much more better and you will see an improvement...
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November 16, 2008

Pros:

None

Cons:

Made me breakout even worse, each day a couple of new cysts would surface.

I tried to be patient and gave differin the benefit of the doubt and stuck with it for 2 months. My skin got worse and I continued to use it because I thought that it might get worse before it got better. I would never use differin again!!!
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October 23, 2008

Pros:

it doesnt smell

Cons:

increases breakouts like cyistic acne

i have had acne for 8 yrs.. ive tried almost everything. u name it. accutane worked the best on my skin for 3 months, i had severe depression, and horrible nosebleeds i dont reccomend it. plus nw i have acne AGAIN. im trying differin but it got worse! and it isnt getting better... honestly, birth control pills work marvels compared to all these "miracle" creams. and some work for some. skins are all different.
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October 20, 2008

Pros:

the first 2 weeks i saw my acne get a little better but after that most of it went within the next 4 weeks. got it free from a prescription

Cons:

redness increases in the first week. some scars visible.

use it with another acne treatment product and it works great. use it by itself and it works ok but not that good.
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June 16, 2008

Pros:

Is a mild acne product that will not irritate sensitive skin. Clears not only pimples but also blackheads.

Cons:

If too much of the product is used if will lead to excessive scaling and dry skin. Initially causes additional pimples.

I have been using Differin on and off for several years. I am now using in every night. I love the product! It is the only acne product I have used that has kept my face clear. I would, and do, recommend the product to anyone. However, don't give up during the first few weeks when your skin begins to break out-stick with it.
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May 16, 2008

Pros:

none

Cons:

made acne worst broke in cysts i never had made face greasey

if you have sensative skin that gets irrated easily don't use i felt i wasn't strong enough
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May 5, 2008

Pros:

Been only using it for over a month and I've been seeing significant improvement.

Cons:

It can dry out your skin quite a bit for the first couple of weeks.

I've been suffering from acne for a very long time and this medication is the best I've used so far. I use Differin XP at night and Neostrata Toning Solution with Clindamycin in the morning. I use a very gentle cleanser (Clean and Clear Facial Cleanser for sensitive skin) and a very light moisturizer(Neutrogena Moisture Oil-Free for sensitive skin). My skin is really clearing up and if I do get any pimples, they are very small and barely noticeable. My scars are also fading. I am very satisfied with the results so far and I look forward to the next couple of months. I recommend it to everyone who has been suffering from acne for a long time like myself.
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April 25, 2008

Pros:

Great. Great. Great. Cleared me up when nothing else worked

Cons:

None really. It dried me around the mouth at first but nothing major.

I used sooo many products and wasted so much time. My derm gave me a sample of this and I demanded a presciption the next day.
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March 23, 2008

Pros:

affordable, effective but it takes too much time so you have to wait and see the effects U_U

Cons:

lot of pimples for the first weeks

It's been my 5 weeks already from the time when I started using differin, at first --- geez all of my pimples worsened than usual, I got lot of pimples (bigger and smaller ones) no space on my chin that doesn't have a pimples and I thought they got irritated or what. Then I've tried to read all of the reviews here on this site, and my doctor was true ' at first it will become worsened and afterwards it will become clear already. Well I've patiently waited for that time even I lose my hope already and tried to give up on that product and use another types of medication. Somehow I've thought that those breakouts caused also by the soap that I'm using ' before I'm using the kojic soap to clear the dark spots, and I've switched to the previous soap that I'm using ' Clearasil daily wash soap and changed the clindamycin to 2% clindamycin, and at last all of my pimples got dried and right now I cannot see any visible pimples ^_____^ im soooo happpppy right now........
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January 29, 2008

Pros:

It gets rid of the little pesky pimples that i hate the most and it helps those stupid ice pick scars or whatever you call them1!!!!

Cons:

makes my face super oily, takes a long time to kick in,

I would reccomend it for people who have patience. This product took many months to work.
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Finding a Doctor

The right dermatologist can make a big difference to your patient experience and the success of your acne treatment plan. Here are the steps to find a dermatologist who is a good fit:

  1. Use the search feature on the American Academy of Dermatology website to look for board-certified dermatologists in your area, and filter the search results for doctors with a special interest in treating acne.
  2. Read online patient reviews of any dermatologists you are considering and ask people you know whether they have any experience with these dermatologists.
  3. Do your research and go to your first appointment with questions prepared.
  4. Listen to what your gut feeling tells you once you see a dermatologist in person. If you are not completely comfortable, try a different dermatologist.

Finding a Doctor

Only a select few plastic surgeons specialize in acne scar revision surgery. Be certain to find a provider who specializes in acne scar repair and who is passionate and experienced in this area.

Be sure to:

  • Look at before and after photos, the more the better, especially patients with similar scarring to your own.
  • Be realistic about results. Look for improvement, not a cure.

Questions to ask a potential scar revision specialist:

  • Are you board certified? Be certain that they are board certified.
  • How long have you been performing these procedures? Normally, the more experience the better, however, some younger surgeons may be more on top of the latest procedures.
  • Can I speak to some of your other patients? Ask for references for several patients who had similar scarring and speak to them about the process and their satisfaction with results.

Red flags:

  • Their story changes: As you discuss different treatment options, if they tend to change their mind easily, or agree with whatever you say, consider this a red flag. A confident, experienced surgeon will possess strong, unwavering opinions.
  • Your gut tells you "no": Trust your gut. If you just don't feel that the doctor is the right fit, trust that and move on. On the other hand, if you feel they are the perfect specialist for you, trust that feeling.