Isotrexin : Erythromycin (2%) and Tretinoin (.05%) Gel

strongly advised! does what it promises :)

Use very small amount only on spotty area. Defo not a morning cream and so not for underneath makeup..it just peels off.

I used it first a couple of years ago and my skin had never been better, I was very impressed. I stopped using it because i went overseas for a year, my skin returned to bad form. However, just started using it again and am once again very impressed.

Ok so most of you might not agree with my results or time period using this product but for me it hasn't done any favours. I have NEVER sufferd with acne as bad this year as I have in the past. A few years a ago I got prescribed "lymacycline" and it did the trick to clear up (or so I think) but this month when I started to develop different signs and more spots than usual I went to the docters for something stronger and he prescribed me this gel "isotrexin". After reading reviews and not finding many good ones I was willing to give it a go and hope that it would work for me. He did specify that it might take a few weeks to work and now I'm three weeks in I refuse to use this gel anymore. After reading reviews I took into consideration that my skin may get worse before it for better, skeptical about using it I had a go for the benefit of my face. However, it has made my face red, sore, dry and uncomfortable. The skin doesn't look healthy and looks inflammed and irritated. I have tried to put moisturiser on to stop the flakiness/dry patches under my makeup but my skin would flake and you can still see the scars. Each day I would wake up with a new painful spot or even a boil under the skin. No matter how much makeup I tried to use it didn't cover or help the situation. I might not have given it long enough to work but during the 3weeks I used it I was in constant pain and discomfort hence why I decided to stop. Everyone is different and will react in different ways. At the moment I'm back using my dermologica products and staying clear of any gels or creams prescribed medically. I hope this don't put you off using it if you do have it, I was just expressing my time whilst using it. Please feel free to ask me any questions x Charlotte 21 :)

I had mild to moderate acne but combination of bad life conditions and habits made it worse. I'm now suffering from moderate to severe acne. I gained weight and I was already prone to pcos. Now I'm diogonised with pcos and I started to take birth control pills. I'm not sure if it's the isotrexin or the pills but my skin is really clearing up. When I first started to use isotrexin, it didn't seem to be working. After 1-2 weeks my skin got worse. I started to have some gigantic pimples that I had rarely had before. I was so upset and I regretted starting the medication. However, after reading some reviews which say it's quite normal at the beginning, I decided to give it a go. Now it's been 3 or 4 weeks since I started to use isotrexin and I can say that there is a dramatic change in terms of acne. All the big, inflamed pimples have become smaller and it is really hard to notice them since they are beneath my skin, not close to the surface. It didn't cause so much irritation. I mean yeah it irritated somehow but it's a quite common symptom in acne topicals. There is only one downside which is the cleaning process. It takes so much time to get rid of the layer it leaves on your skin. I use a face wash called TTO and a lot of water, yet it takes almost 20 minutes to get rid of the gel on my face in the morning. Maybe I should also use a make-up cleaner for that. In conclusion it is really a good topical gel even for severe acne but you must be patient. You will probably breakout more first but it's temporary. Don't forget to apply it only on the legions and it should be a thin layer. I hope this will work for you and you will have the clear skin you are yearning for. Don't make it a big deal though. If you get obsessed with your acne, it only gets worse.

hi! I was prescribed with this treatment after i startedto break out a little bit after 6 months of roaccutane. My breakouts were pretty mild but they wer really stressing me out, so, i have been using this for 4 days and my skin is significantly lesr oily and a few whiteheads are popping out. Also, my inflamed acne is drying up and the spots that are coming througg now are smaller and less inflamed. I would recommend this products for pppl with mild to moderate acne! Its better than panoxyl

it does the job and is effective

It's early day's, this is my second week and so far some parts of my skin look fine and maybe slightly better but it has brought out some horrible sports around my jaw and chin area. I will stay strong though and keep on trying as i know it takes longer than a week to clear up acne! Im also going to try what someone earlier mentioned which is moisturize first then apply. Also id like to add im only using it at night. I will be back in a month to update on how im getting on.

doesnt dry my skin or peel or anything..no side effects worked amazingly well literally all gone lil bit of redness from small spots clearing up never had big ones little ones under eyes and forehead made it smooth jus tiny bit red basicly cleared it all up for 8 weeks now its going back to how it was and not working

use it because it does work. and also persist with it cos im sure it will definetley have some effect. ive been using it 5 weeks and its certainly cleared lots of spots up but has just made them more inflammed. fewer spots but does look worse from the outside. surely after time (say for me another month?) they should go... :D