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Posted (edited)

well i have a 2 month supply of 10 mg tane sitting on my desk for a week now. i decided to give vitamin c megadosing a shot before the plunge after seeing a post on here about someone doing a fruit fast which cured their acne in about a year. and the results have been incredible. solid 60% improvement in skin but also my digestion and sleep have improved so much. it turns out vit c is crucial for transformation of cholesterol to bile acids and adrenal steroidogenesis (cortisol- antinflamatory and regulates blood sugar) as well as fighting infections..we could all just be experiencing subclinical scurvy. im sure it can only help pas sufferers. 

i have my base cholesterol and trigs from end of last year (was on high end) and plan to test every month including vitamin c, even though blood tests dont account for tissue/organ ascorbate saturation it will be interesting. im so hopeful and excited.

i have been taking 6 grams of sodium ascorbate/day and will increase to 10 grams. in addition i have been freshly squeezing 1 whole pack (3kg) of oranges and eating up to 12 kiwis a day and eat 2 normal meals/day for lunch and dinner.

Edited by pimple pimp

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Posted

i dunno, i feel like were making progress. the good side of everything is that we are aware of how the system works and how important taking care of our own health is.

I've learned quite a few things about the fungi kingdom recently and its proven results in aiding the brain and body. Look up Lion's mane. And read up on the properties of different mushrooms.

Also, Did you know that over 40% of pharmaceuticals are created from mushrooms. The more you know. The closer you are to finding a solution. I quite enjoy finding an alternative treatment to my ailments. Quite a task, but i'm up for it.

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Posted
12 hours ago, ailaeshiz said:
13 hours ago, Gladiatoro said:

For people who have sexual disfunction after istotretinoin exposure , here is a re-cap .
https://rxisk.org/accutane-30-years-of-trading-our-sex-lives-for-clear-skin/

The worst part of all this is no matter how many people come forward with their symptoms the medical community still refuses to acknowledge it as a problem.
They obviously don't think CHEMOTHERAPY has any long term effect on the human body lol... 

Another re-cap for nebs ....

https://www.thehealthyhomeeconomist.com/say-no-to-accutane/

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Posted (edited)

For people considering isotretinoin  I would recommend to stay far away from caring and loving derms  , your taking a huge gamble with your health and what kind of debilitating side effect will you have down the road ???? That is the question , if this drug shortened my life I will be severely pissed off . 30 years later they still don't know how it works hmmm... , I think I know more about this drug than any derm  after years of extensive study it goes something like this...
another re- cap .....

I want to begin this by saying that i was in your position. I had bad acne. I'm writing this to provide some insight to what it's been like the last 3 years after my course of accutane (some information that i would have eaten right up before i started treatment). Let me start off by saying - this drug works. For most, if not all of middle/high school, I had very bad acne that was resistant to doxycycline, minocycline, proactiv, Murad products, benzoyl peroxide, sailicylic acid, and all the wipes i could get my hands on. You more than likely will be free from acne at least for a few years after treatment, and it's absolutely wonderful! Being able to walk around without having to check mirrors for a new red/white bump on your face is as great as you think it would be. Looking back it seems like i was a completely different person. You're probably thinking: if it works so well, why the lackluster rating then?! This drug works wonders but there is absolutely a reason as to why they're so serious about prescribing it. They are very cautious because this stuff is freaking legit - it alters your body in a permanent way. Once you've finished your course there is no going back. In fact, at the time of writing they still do not understand exactly how it works - but it affects acne. This was originally made to be a drug for cancer patients (yeah, people that had nothing left to lose and were willing to try something that could potentially debilitate them if it meant surviving! crazy right?) So I went on the medication and throughout the course felt nothing but the normal side effects of dry lips, skin, nosebleeds, dry eyes and easily scarring (just a scratch on accutane can turn into a permanent scar hah, i have a few reminders). Things went through without a hitch and i was acne free! I would notice people staring at me, and if i could guess what they were thinking it would be "How in the hell did that pizza face get porcelain clear skin?!" Strangely, the side effects of this medication slowly ease their way into your life after treatment (the effects are permanent after all). Expect something along the lines of joint pain, gastrointestinal issues, and mental health dips. These tend to be the most serious. When people get these issues they disregard it as natural, how in the world could they be associated with something they took 3, 5, even 10 years ago? Long story short in convincing you this are legit, the original manufacturers of accutane (Roche) went out of business due to lawsuits and had huge payouts of millions upon millions of dollars to peoples lives they had negatively changed (mostly focusing on permanent gastrointestinal issues). I could talk about this for hours but to avoid making it THAT lengthy, here's the summary: I can't stress enough how EXTREMELY important it is for you to consider these potentially permanent side effects. When i took it i couldn't care less about side effects, all i wanted was my acne to be gone! But there are people who used to play sports, ran, and workout - now experience severe pain by simply walking due to joint issues (and it's seemingly permanent unfortunately). If your acne isn't really that bad, or could go away within a couple of years normally, it is up to YOU to consider taking this drug. There are dermatologists out there who will prescribe this to people with just a few pimples, which is unecessary given how serious the side effects could be. Read up on peoples experiences years after their treatment and make an informed decision!!! God bless :)  definently  NOT  my story , I had very mild acne ....  but you get the point , " people with a few pimples " would be my story .
Let me finish off in saying that in the NEAR future any kind of chemotherapy treatment will be considered and ACT OF CRIME against humanity , mark my words .

Edited by Gladiatoro

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Posted

One derm put it this way , it’s the lesser of the evil , it saves more lives than it takes.  I’m not so sure.

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Posted

My derm didn’t put it anyway, either way she lead me down a horrible path....

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Posted (edited)

This is a newer company out of silicon valley. This sort of reminds me of 23andme. This is a project that might grow and develop with time.
https://ubiome.com/

Your microbiome is the unique collection of trillions of microorganisms in and on your body. 


uBiome uses machine learning, artificial intelligence, and advanced statistical techniques, as well as our patented precision sequencing™ process to analyze the microbes in your sample. Test once, or track your microbiome over time – the choice is yours.

Something to keep in mind is its not just bacteria in your gut, but on your skin as well. 

Isotretinoin and lymecycline treatments modify the skin microbiota in acne

http://onlinelibrary.wiley.com/doi/10.1111/exd.13397/full
First published: September 2017

 

And then looking even further.
https://news.heart.org/gut-bacteria-hold-clues-to-heart-health/
 

Gut bacteria hold clues to heart health

By AMERICAN HEART ASSOCIATION NEWS

 hereditary factors can account for only about 15 percent of cardiovascular risk, meaning environmental causes account for the rest, said cardiologist Stanley Hazen, M.D., Ph.D., chair of the Department of Cellular and Molecular Medicine at the Cleveland Clinic’s Lerner Research Institute.

“I think the magnitude of the importance of the gut microbiome is far greater than we ever anticipated,” Hazen said.

These bacteria and other microbes, known collectively as the gut microbiota, or microbiome, are influencing heart health in previously unseen ways, research is showing.

“People are still getting their head around how something in the gut can affect the heart,” 

preventing or treating cardiovascular disease will not be as straightforward as simply using probiotics to make complex communities of gut microbes match a “healthy” profile. “We have to get to the function of bugs,” Hazen said, “and how that is leading to a change in host physiology.”

Edited by guitarman01

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Posted

How do you know when your gut health is ok??

Probiotics ✔️
Mutaflor ✔️
Sauerkraut ✔️
Kombucha ✔️
Vit K ✔️
seen specialists inc gastroenterologist✔️

What else is there left to do??


 
 

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Posted
On 1/2/2018 at 11:42 PM, Colinboko said:

Been having slight prostate pain quite often lately... 

It’s not excruciating and generally goes away after some time but it’s still there. Usually after masturbation 

Oh man, I have exactly the same issues for over a year now. I'm after accutane "treatment" for about 3 years now.

I experience strong pain, cramp-like after masturbation (doesn't always happen but often), after wet dreams. It generally occurs in the night, where I wake up with the pain that won't go away for 20-40 mins and then subsides. If I abstain from masturbation I get none of these pains.
I googled it and found this which explains it well - https://en.wikipedia.org/wiki/Proctalgia_fugax

Seeing your post surprised me a lot, maybe it's not related to Accutane hehe.

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Posted
2 hours ago, AccuNate said:
Oh man, I have exactly the same issues for over a year now. I'm after accutane "treatment" for about 3 years now.

I experience strong pain, cramp-like after masturbation (doesn't always happen but often), after wet dreams. It generally occurs in the night, where I wake up with the pain that won't go away for 20-40 mins and then subsides. If I abstain from masturbation I get none of these pains.
I googled it and found this which explains it well - https://en.wikipedia.org/wiki/Proctalgia_fugax

Seeing your post surprised me a lot, maybe it's not related to Accutane hehe.
No. It definitely is..

something is seriously wrong with my hormones 

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Posted
35 minutes ago, Colinboko said:
No. It definitely is..

something is seriously wrong with my hormones 

Welcome to tane world. Tane affects every hormone there is... from testosterone and thyroid onwards. It is now known it affects pituitary hormones as well. These imbalances could be transient, or permanent. 

Have you tested all hormone levels possible? 

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Posted (edited)
15 minutes ago, fiksi said:

Welcome to tane world. Tane affects every hormone there is... from testosterone and thyroid onwards. It is now known it affects pituitary hormones as well. These imbalances could be transient, or permanent. 

Have you tested all hormone levels possible? 
You comment is right on the money , somehow we are all connecting by one single factor isotretinoin.
It is after all a brotherhood. Edited by Gladiatoro

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Posted
11 minutes ago, Gladiatoro said:
You comment is right on the money , somehow we are all connecting by one single factor isotretinoin.
It is after all a brotherhood.

Let me tell you this... I had a severe reaction to accutane, my basic bloodwork was fine, but I felt like a dying man. 98% strength gone... this is accutane induced myositis, with dizzyiness/ataxia, headache, pain in all muscles and joints. 

The stuff that we test is quite limited... even these basic tests rarely includes CK, ANA or such stuff. 

Doctors will say- side effects not likely. But I think 98% sufferers never report anything. Sometimes they will think you are crazy or say "accutane doesn't cause xyz".

In some cases, autoimmune diseases awaken after accutane as well. 

Latest research I read, says accutane affects pituitary gland "in unknown ways", alters hormone balance there... and that this "likely" helps acne, but what abotu other systems? 

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Posted (edited)
11 minutes ago, fiksi said:

Let me tell you this... I had a severe reaction to accutane, my basic bloodwork was fine, but I felt like a dying man. 98% strength gone... this is accutane induced myositis, with dizzyiness/ataxia, headache, pain in all muscles and joints. 

The stuff that we test is quite limited... even these basic tests rarely includes CK, ANA or such stuff. 

Doctors will say- side effects not likely. But I think 98% sufferers never report anything. Sometimes they will think you are crazy or say "accutane doesn't cause xyz".

In some cases, autoimmune diseases awaken after accutane as well. 

Latest research I read, says accutane affects pituitary gland "in unknown ways", alters hormone balance there... and that this "likely" helps acne, but what abotu other systems? 
It’s heartbreaking what these derms do to kids and young adults. For a few red spots.

Basically traumatizing them for life and messing up their young bodies. Some how this drug went from a last resort drug for severe cystic nodular  acne to hey young man / woman you have a few red spots here is some chemotherapy for you . Edited by Gladiatoro

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Posted
43 minutes ago, fiksi said:

Welcome to tane world. Tane affects every hormone there is... from testosterone and thyroid onwards. It is now known it affects pituitary hormones as well. These imbalances could be transient, or permanent. 

Have you tested all hormone levels possible? 
I need to get testosterone and the whole works done still. My doctor is a pain in the ass and just cause I’m 22, he doesn’t want to test my hormones... 

I truly think my problem is hormone related. I mean I found an article the other day that showed reduced FSH and LH being the cause of vocal weakness and loss of vocal stability. Like I can’t talk over crowds anymore, can’t even sing in my chest voice without it breaking. I had a vocal coach in high school that lost her voice for a while after pregnancy/postpartum due to the hormonal changes. Idk my story just seems very hormonal. 

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Posted
7 minutes ago, Gladiatoro said:
It’s heartbreaking what these derms do to kids and young adults. For a few red spots.

Basically traumatizing them for life and messing up their young bodies.

I will say this- my case was quite tough, years of everything... strong back/scalp acne(interfered with daiyl life)... this is an extremely dangerous drug, which may only be considered in most extreme cases. 

However, I will say we see here people with 3 pimples who get 80mg a day. Basically, near 2mg/kg dose for a young girl. Crazy. Majority of people never need to consider accutane. 

I also think derms don't warn us properly of all consequences. I was so ill from accutane, man, I thought I might end. Also, FYI, I didn't have much side effects until almost 5th month... then this weakness began. I thought I had ALS or some terminal disease. 
6 minutes ago, Colinboko said:
I need to get testosterone and the whole works done still. My doctor is a pain in the ass and just cause I’m 22, he doesn’t want to test my hormones... 

I truly think my problem is hormone related. I mean I found an article the other day that showed reduced FSH and LH being the cause of vocal weakness and loss of vocal stability. Like I can’t talk over crowds anymore, can’t even sing in my chest voice without it breaking. I had a vocal coach in high school that lost her voice for a while after pregnancy/postpartum due to the hormonal changes. Idk my story just seems very hormonal. 

Just pay yourself and do it. Yes... destruction of vocal cords is also an accutane possible effect. Hormonal panel should be done. 

It's just, some docs may say you are crazy- they will give you valium and say to calm down. You are young, nothing is wrong. Yes.

I was on mino for quite some time, and while I had sides, nothing so serious, and also... it's like 20 side effects listed in total. tane is like 1000+. It is very systemic- affecting basically every organ and hormone. 

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Posted (edited)
Not saying lyme has any relevance, just looking further afield to try and understand other conditions and to see what success they might have had. Lyme sufferers also deal  with sexual sides.
To understand Lyme doctors are being told to look at inflammation, infection and immune dysfunction.
Note most test come back clear.

I think we all know by now that we are looking at multi organ disorder just like autism brought on by vaccines.
gastrointestinal, neurological and immunological.  

The doctor here talks about low white cell count, low platelets count and elevated liver functions with the classical symptoms as markers.
Anyone got any tests results to share.

We really need a wide spectrum of test done including skin biopsies - Uk guys really have no excuse to get all testing done.

We really should get a comprehensive list of tests so that doctors could be advise because as we all know they have no clue.

Is there anyone up for going to the GP and demanding complete testing?
If anyone wants some guidance on what test to ask for please state and we can put our heads together.


Lyme + low T Edited by hatetane

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Posted (edited)
2 hours ago, hatetane said:
Not saying lyme has any relevance, just looking further afield to try and understand other conditions and to see what success they might have had. Lyme sufferers also deal  with sexual sides.
To understand Lyme doctors are being told to look at inflammation, infection and immune dysfunction.
Note most test come back clear.

I think we all know by now that we are looking at multi organ disorder just like autism brought on by vaccines.
gastrointestinal, neurological and immunological.  

The doctor here talks about low white cell count, low platelets count and elevated liver functions with the classical symptoms as markers.
Anyone got any tests results to share.

We really need a wide spectrum of test done including skin biopsies - Uk guys really have no excuse to get all testing done.

We really should get a comprehensive list of tests so that doctors could be advise because as we all know they have no clue.

Is there anyone up for going to the GP and demanding complete testing?
If anyone wants some guidance on what test to ask for please state and we can put our heads together.


Lyme + low T

I actually had Lyme man- I really had Lyme. I never knew I ever had a tick... developed malaise, fever, and a rash. Treated with tetras, never done any actual testing because case was clear. 

However, Lyme often quiets down, and then becomes silent striking later things liek brain, heart, nerves, years later. It can be a chimera disease. Lyme does have an active spirochette at work.

Roaccutane damage, I think, is cumulative and then it alters body systems. Everyone gets damaged by tane, the question is how much, and when this will show(or if). Unfortunately, the death of glands like those lubing eyes can be permanent, as can night vision changes etc. 

The damage from tane is from period of taking, and perhaps some time after. The problems appearign later are just the result of altered functioning taking its toll. 

I think tane panel should include thyroid and ANA tests, and all hormones + CK. At minimum. 
  Edited by fiksi

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Posted
3 hours ago, fiksi said:

I will say this- my case was quite tough, years of everything... strong back/scalp acne(interfered with daiyl life)... this is an extremely dangerous drug, which may only be considered in most extreme cases. 

However, I will say we see here people with 3 pimples who get 80mg a day. Basically, near 2mg/kg dose for a young girl. Crazy. Majority of people never need to consider accutane. 

I also think derms don't warn us properly of all consequences. I was so ill from accutane, man, I thought I might end. Also, FYI, I didn't have much side effects until almost 5th month... then this weakness began. I thought I had ALS or some terminal disease. 
Just pay yourself and do it. Yes... destruction of vocal cords is also an accutane possible effect. Hormonal panel should be done. 

It's just, some docs may say you are crazy- they will give you valium and say to calm down. You are young, nothing is wrong. Yes.

I was on mino for quite some time, and while I had sides, nothing so serious, and also... it's like 20 side effects listed in total. tane is like 1000+. It is very systemic- affecting basically every organ and hormone. 
I had them looked at. It’s not “destruction” necessarily. The hormones just control the amount of muscle. 

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Posted (edited)
10 minutes ago, Colinboko said:
3 hours ago, fiksi said:

 
I had them looked at. It’s not “destruction” necessarily. The hormones just control the amount of muscle. 

Accutane is a known myotoxic drug, and it can destroy/damage muscles(sometimes with elevated CK). So cords can be affected in this way as well. Pure muscle destruction is possibly mostly reversible, but altered hormonal glands may not be. 

There are known death cases from this. A young guy had tane cause extreme stress on muscles, and he hiked and exerted very high effort as well. He collapsed and died later. In absence of tane the stress on his muscles would not have caused this. Cause of death? We coudl say, accutane.

Your case may be different, but tane does affect muscles(and joints) directly. 

However, now when you say this, I also noticed my voice became "hoarser", so to say, on tane.  Edited by fiksi

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feeling pretty backed up after allochol. I suppose I didnt quite reach the bile expulsion stage and Im waiting my liver is waiting stagnantly for it now, although I stopped taking the allochol over a week ago. Trying psyllium husk to get things moving. Will get the remainder allochol tablets I have and see what another week does. Also will try malic acid capsules I have to open things up.

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Posted (edited)
17 minutes ago, fiksi said:

Accutane is a known myotoxic drug, and it can destroy/damage muscles(sometimes with elevated CK). So cords can be affected in this way as well. Pure muscle destruction is possibly mostly reversible, but altered hormonal glands may not be. 

There are known death cases from this. A young guy had tane cause extreme stress on muscles, and he hiked and exerted very high effort as well. He collapsed and died later. In absence of tane the stress on his muscles would not have caused this. Cause of death? We coudl say, accutane.

Your case may be different, but tane does affect muscles(and joints) directly. 

However, now when you say this, I also noticed my voice became "hoarser", so to say, on tane. 
Mine isn’t hoarse. It’s weak.. has no strength. I’m having problems with proper closure. Hoarse has to do with the actual mucosa of the cords being affected. My mucosa is fine (been examined by the best ENT in the country) it’s the muscle that is the problem.  Edited by Colinboko

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Posted
3 minutes ago, Colinboko said:
20 minutes ago, fiksi said:

Accutane is a known myotoxic drug, and it can destroy/damage muscles(sometimes with elevated CK). So cords can be affected in this way as well. Pure muscle destruction is possibly mostly reversible, but altered hormonal glands may not be. 

There are known death cases from this. A young guy had tane cause extreme stress on muscles, and he hiked and exerted very high effort as well. He collapsed and died later. In absence of tane the stress on his muscles would not have caused this. Cause of death? We coudl say, accutane.

Your case may be different, but tane does affect muscles(and joints) directly. 

However, now when you say this, I also noticed my voice became "hoarser", so to say, on tane. 
Mine isn’t hoarse. It’s weak.. has no strength. Hoarse has to do with the actual mucosa of the cords being affected. My mucosa is fine (been examined by the best ENT in the country) it’s the muscle that is the problem. 

I understand. How are your other muscles though? 

The effects of tane are multifold, and through many channels. We may each have a different set of effects, where some overlap. In your case, it could be hormonal. even the dose effect on each person differs(even people of same sex/weight/age etc).

My biggest fear is that some are now known to be possibly irreversible. 

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Posted (edited)

The drug leaves the system in a couple of months derms say of course it does LIARS. I say do NOT insult my intelligence.

We all know it permanently alters the human body . No question.

Edited by Gladiatoro

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