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Someone should really make an introduction thread or an explanatory opening post of these promising scar treatments that is available now or near in the future if there isn't one already. Especially for people like me whose mother language is other than English it would be much easier to seek information compared to reading a thread which has over 100 pages. I know this http://www.acne.org/scars.php but it's rather narrow.
I agree. But isn't there one in the first post of this thread? Or do you mean something else?
Btw, are you Dutch? 
I want non denatured ECM, but if this improved the defects I'd do it.
Well, this ECM has one difference so it's probably 99% non-denatured or something like that. You could look for people in your vicinity who also have it and are willing to use it? Or you could tell surgeons about it and suggest to them to use it? If only on you? They're using RGTA-OTR4120 which is made by OTR3 from France. RGTA stands for "ReGeneraTing Agent" and they've got access to this ECM through a collaboration with Prof D. Barritault who is from OTR3. I've posted a link to OTR3's website a few posts back.
In any case, stay tuned for more updates from me in the very near future. I didn't have time to call anybody today and tomorrow I won't have time either, so it will be next week that I'll continue my research.
Someone should really make an introduction thread or an explanatory opening post of these promising scar treatments that is available now or near in the future if there isn't one already. Especially for people like me whose mother language is other than English it would be much easier to seek information compared to reading a thread which has over 100 pages. I know this http://www.acne.org/scars.php but it's rather narrow.
I agree. But isn't there one in the first post of this thread? Or do you mean something else?
Btw, are you Dutch?
Yes there is but it provides only a little information whereas that pdf is a bit too precise.
And no, I'm not Dutch. I'm from Finland. 
Yes there is but it provides only a little information whereas that pdf is a bit too precise.
And no, I'm not Dutch. I'm from Finland.
I agree; the pdf is very large! lol It's very useful, though. But yeah, an explanatory post could be a good idea. One thing I also think is that maybe they could post a warning regarding that pdf because it contains some photos which can be disturbing for some. I know I got startled a bit..
Anyway, you're English is very good, Mies! Mies is also a popular Dutch name so that's why I thought you might have been Dutch.
Scarless healing gives me an idea that when the healing process is still in progress it's possible to prevent a scar from forming so that the damaged tissue can be healed completely. However, when we talk about our scars at this moment they are already formed. So when this new revolutionary cure will be available how those existing scars will be treated? And one more question: do you think that this scarless healing will be available to public by 2011?
BTW Mies means the same than english word "man" in Finland.
Scarless healing gives me an idea that when the healing process is still in progress it's possible to prevent a scar from forming so that the damaged tissue can be healed completely. However, when we talk about our scars at this moment they are already formed. So when this new revolutionary cure will be available how those existing scars will be treated? And one more question: do you think that this scarless healing will be available to public by 2011?
BTW Mies means the same than english word "man" in Finland.
well we have to remove our scars first. Like have them surgically cut out. I have a question for everyone though: how deep is scar tissue? Apparently it extends into the dermis but I don't know how deep that is. But if you cut out your scar and you bleed does that mean you have extended beyond the dermis? Can you bleed if you don't cut your dermis?
Anyone here? I do not...have you made any more calls? I'd love to hear about them.
As it happens, I was meaning to post today! lol But I wanted to post here today saying that due to circumstances in my life, I have not been able to make any calls this week...
I also need some time to prepare for the next calls so the next call will be on Monday, most likely. Like I said earlier; I mean to call a plastic surgeon and ask him/her what he/she thinks of what seabs135 says regarding decorin. I'll also ask him/her about the possibility of complete regeneration as opposed to partial regeneration which the previous person I spoke to sort of said was what that RGTA he has achieves. The results may have been "very beautiful" in the cases it worked to an extent but if complete regeneration is possible, then of course we're going to be even more interested in an approach which achieves that, now won't we? Anyway, I'm going to talk to him/her about all of that, in any case. I'll see if I can get some clear answers.
After that, I'll probably ask the University of Twente (of whom I posted videos earlier) what they're developing, exactly. Should be interesting, too.
And after that, I don't know who I'll contact yet... But maybe before then I'll have found the people who are able to fix scars! haha Wouldn't that be cool? lol Or maybe I already have... Who is to say? I mean that RGTA that is out there now and that people can get treated with may just be what we've been looking and hoping for. I'm not excluding the possibility, personally. But there is still no evidence of this, so..... And there are many, many people here doing things in terms of tissue regeneration which I intend to look into one by one. So stay tuned for more updates from me, I'd say.
Scarless healing gives me an idea that when the healing process is still in progress it's possible to prevent a scar from forming so that the damaged tissue can be healed completely.
Exactly.
However, when we talk about our scars at this moment they are already formed. So when this new revolutionary cure will be available how those existing scars will be treated?
They'd have to be cut out or dissolved by an enzyme and then they'd apply the product used. I think the option of cutting the scar out is most likely to be the case, though.
And one more question: do you think that this scarless healing will be available to public by 2011?
I don't know... There is something out there now, like I mentioned earlier which is called RGTA-OTR4120. But it is not 100% sure if it is something that realizes actual scarless healing.
Another thing (Juvista) seems to be in development hell, so to speak; a lot of postponing/delays... So who knows when that comes around, you know? I personally doubt that Juvista will be something that realizes actual scarless healing. But you never know...
Other than that, there might be other approaches (like what seabs135 says, regarding decorin) which, if they work, should be available fairly soon, if you ask me. Because you'd just be able to go to a hospital and get it done. But that is not what I know but what I think.
Also, there seems to be another thing being developed at a Dutch university. I don't know if it works or when it will be available. But like I said earlier; I'm going to look into it and I'll keep everybody updated on my findings
So if it will be available by 2011? I guess the answer is "maybe". 
BTW Mies means the same than english word "man" in Finland.
Really? Cool. What's the Finnish word for "woman" then, Mies?
My name is Alwin. A German name which means "person without acne". Just kidding! haha It means "loyal friend".
well we have to remove our scars first. Like have them surgically cut out. I have a question for everyone though: how deep is scar tissue? Apparently it extends into the dermis but I don't know how deep that is. But if you cut out your scar and you bleed does that mean you have extended beyond the dermis? Can you bleed if you don't cut your dermis?
I don't know. That's a good one. I guess it varies as far as how deep different scars go?
Would it not be better to simply ablate the surface of the scar say for instance a boxcar scar, .5-1.0 mm deep with a laser. Then apply what ever it is ecm or stemcell ect for regeneration. I can only hope something can come soon to repair scars, i really want my confidance back. Life is so bleak walking around with scars. If i could see 70% + improvement i would glady pay 40,000 just to throw a figure out there.
Would it not be better to simply ablate the surface of the scar say for instance a boxcar scar, .5-1.0 mm deep with a laser. Then apply what ever it is ecm or stemcell ect for regeneration.
At least it sounds better option than cutting one's skin with knife before a treatment although the treatment would provide scarless healing.
Really? Cool.
My name is Alwin. A German name which means "person without acne". Just kidding! haha It means "loyal friend".
Finnish word for "woman" is "nainen", Alwin.
"Tekem¤si ty¶ on antanut monelle tietoa. T¤m¤ tieto on antanut toivoa paremmasta, mik¤ on ollut suunnattoman t¤rke¤¤. Kiitos siit¤." It means that the work you have done has given information to many people. This information has given hope for a better future which has been very important. Thank you for that.
Finnish word for "woman" is "nainen", Alwin.
"Tekem¤si ty¶ on antanut monelle tietoa. T¤m¤ tieto on antanut toivoa paremmasta, mik¤ on ollut suunnattoman t¤rke¤¤. Kiitos siit¤." It means that the work you have done has given information to many people. This information has given hope for a better future which has been very important. Thank you for that.
Well, that's what loyal friends are for! haha Seriously, you're welcome, Mies.
Btw, I love that word "suunnattoman". It sounds so cool!
Would it not be better to simply ablate the surface of the scar say for instance a boxcar scar, .5-1.0 mm deep with a laser. Then apply what ever it is ecm or stemcell ect for regeneration.
That's a good idea... I'll ask surgeons about that. But personally, I think it may be so that one really needs to cut the scar(s) out... I mean I think it needs to go away 100% so that your body can fix that entire area... But I'll ask surgeons about this.
I can only hope something can come soon to repair scars,
Well, it's being worked on. Rest assured.
i really want my confidance back. Life is so bleak walking around with scars. If i could see 70% + improvement i would glady pay 40,000 just to throw a figure out there.
I'm of the opinion that life doesn't have to be bleak with scars... But it certainly can be. I've obtained my facial scar 12 years ago and there were times when my confidence was destroyed, as well. Which was very difficult. It caused a lot of anxiety which was a real burden, you know? But in time things got better in terms of this... Now, it's a different story. I mean I don't have those anxieties anymore. It took a long time for me to come to terms with it, though.
Anyway, I'll continue my research next Monday...
If you type "Pixie dust helps finger grow" on YouTube you can see how one kind of powder helped a man grow his finger back. Pretty amazing I would say. This might have been here earlier but if you haven't seen it it's worth watching. I don't see any reason why this wouldn't work on scars too.
If you type "Pixie dust helps finger grow" on YouTube you can see how one kind of powder helped a man grow his finger back. Pretty amazing I would say. This might have been here earlier but if you haven't seen it it's worth watching. I don't see any reason why this wouldn't work on scars too.
Yes, I now about that. I think the "pixie dust" is a product called ACell. I remember people here saying that they saw photographs of patients treated with that by doctors and one showed good results and the other didn't as much. But in the latter case, they said, the doctor didn't use it as well as he could. At least that's what they thought.
Personally, I'm not fond of the idea of getting treated with ACell as it is made from bladders of pigs, if I remember correctly. Some organ of a pig, in any case. And that's just a bit too weird for me. I'm a vegtarian, too. lol That aside, I can see it helping... It's just that I don't know to which extent.
I've stumbled upon a site of a company which appears to have used a matrix product made by OTR3 which is the company that made RGTA-OTR4120 which I mentioned earlier. They use another product than RGTA-OTR4120, I think... I'm not 100% sure about that. It might be the same thing.
Anyway, among other things, they have photographs on their site of patients who have been treated with it. The photographs are pretty much all of wounds which are still healing. You can watch them but I should warn you that they can be distressing to see. As, again, some of them are photographs of large open wounds.
Anyway, I'm going to try to call more researchers etc. over the course of the next few days.
Personally, I'm not fond of the idea of getting treated with ACell as it is made from bladders of pigs, if I remember correctly. Some organ of a pig, in any case. And that's just a bit too weird for me. I'm a vegtarian, too. lol That aside, I can see it helping... It's just that I don't know to which extent.
The ECM in pigs is the same as the ECM in your body. And if they used non denatured ECM you'd get, your body flooding it with decorin, and 100% regeneration without scarring wether its from a pig or yourself. To me its all about non denatured ECM. If only they would just use that non denatured stuff, instead of the stuff that gets denatured by the body.
The ECM in pigs is the same as the ECM in your body. And if they used non denatured ECM you'd get, your body flooding it with decorin, and 100% regeneration without scarring wether its from a pig or yourself. To me its all about non denatured ECM. If only they would just use that non denatured stuff, instead of the stuff that gets denatured by the body.
That might be so... But it just doesn't sit well with me, psychologically. Everybody's different. lol
I'll look into this RGTA some more, ok? I'll try to get some confirmation from the people who make it regarding if it's in fact denatured or not.
I already received a reply from OTR3. It was written by Denis Barritault who I mentioned earlier (he's the person through whom that Dutch hospital has access to RGTA). Anyway, here's the e-mail I sent OTR3:
Dear reader,
I was wondering if you could inform me about the following; I've heard that only an ECM which is 100% non-denatured is able to prevent scarring from occurring and therefore able to create an environment in which the body can regenerate tissue completely.
Is this so? And if so, then is RGTA-OTR4120 100% non-denatured?
Kind regards,
Alwin, The Netherlands
In the reply to this, Mr. Barritault said that RGTA mimics an element of the ECM and by doing so is able to induce real regeneration. Which was demonstrated in several in vivo models of which one involved skull bone. But scarring occurs in all tissues, he said.
He said that just like in a scaffold around a building, you have vertical and horizontal bars and the RGTA bridges some bars so that it builds a "ladder" that will allow proper signals to get positioned around the cells, mimicking the environment created by the ECM resulting in the placement of the natural signals in the right doses. It tells the body how the tissue was originally organized.
Anyway, I mentioned decorin to him and what that man from the Dutch hospital said about him not being 100% sure if it works every time for everybody...but I haven't received a reply from Mr. Barritault regarding those things yet.
I just wanted to tell those of you who read what I post that my computer crashed big time. So that's why I haven't been able to post this last week. On top of that I haven't had the time to call anybody this week because of...well...a whole bunch of things that required attention. lol So I'm going to bring my computer back from the dead this weekend and hopefully be calling people all over Holland regarding the regeneration of skin next week.
Btw, does anybody have any thoughts regarding RGTA-OTR4120? I know it's not a 100% non-denatured ECM but it's something which just might have the same effect? Anyway, just curious what you guys think of it.
I just wanted to tell those of you who read what I post that my computer crashed big time. So that's why I haven't been able to post this last week. On top of that I haven't had the time to call anybody this week because of...well...a whole bunch of things that required attention. lol So I'm going to bring my computer back from the dead this weekend and hopefully be calling people all over Holland regarding the regeneration of skin next week.
Btw, does anybody have any thoughts regarding RGTA-OTR4120? I know it's not a 100% non-denatured ECM but it's something which just might have the same effect? Anyway, just curious what you guys think of it.
My computer broke a few weeks ago too.
I've just got around to scanning RGTA-OTR on google I personally do not currently know much about it yet.